Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Immunogen sequence: LDICSKNPCH NGGLCEEISQ EVRGDVFPSY TCTCLKGYAG NHCETKCVEP LGLENGNIAN SQIAASSVRV TFLGLQHWVP ELARLNRAGM VNAWTPSSND DNPWIQVNLL RRMWVTGVVT QGASRLASHE YLKAFKVAYS LNGHEFDFIH DVNKKHKEFV GNWNKNAVHV NLFETPVEAQ YVRLYPTSCH TACTLRFELL
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AGS; Breast epithelial antigen BA46; EGF/factor VIII; HMFG; Lactadherin; medin; MFG-E8; MFGM; milk fat globule glycoprotein; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; MP47; O-acetyl disialoganglioside synthase; O-acetyl GD3 ganglioside synthase; O-acetyltransferase milk fat globule membrane protein; O-acetyltransferase Milk fat glolbule membrane protein; SED1; sperm associated antigen 10; sperm surface protein hP47; Sperm surface protein SP47
Gene Aliases: AA408458; AGS; AI325141; BA46; EDIL1; HMFG; hP47; HsT19888; lactadherin; MFG-E8; MFGE8; MFGM; MFGME8; MFGMP-E8; MP47; OAcGD3S; P47; SED1; SPAG10
UniProt ID: (Human) Q08431, (Mouse) P21956, (Rat) P70490
Entrez Gene ID: (Human) 4240, (Mouse) 17304, (Rat) 25277
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