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Invitrogen
Reconstitute at 0.5 mg/mL in sterile PBS.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
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Protein Aliases: EGF/factor VIII; Lactadherin; MFG-E8; MFGM; milk fat globule glycoprotein; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; MP47; SED1; Sperm surface protein SP47
Gene Aliases: AA408458; AI325141; lactadherin; MFG-E8; Mfge8; Mfgm; MP47; P47; SED1
UniProt ID: (Mouse) P21956
Entrez Gene ID: (Mouse) 17304
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