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Product Details
MA1-771
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
F15 P3 B6
Immunogen
Synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_889472
Product Specific Information
MA1-771 contains 100 µg of in vitro produced, protein A purified antibody (1 mg/mL) in PBS containing 1 mg/mL BSA and 0.05% sodium azide.
MA1-771 detects MMP-1 from human samples.
MA1-771 has been successfully used in Western blot applications. By Western blot, MA1-771 detects a ~50 kDa band representing MMP-1 from A431 and K562 cell lysates.
The MA1-771 immunogen is a synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagenase; Fibroblast collagenase; Interstitial collagenase; matrix metallo protease; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; Matrix metalloproteinase-1; Matrix metalloproteinase1; MMP; MMP-1; MMPs
Gene Aliases: CLG; CLGN; MMP1
UniProt ID: (Human) P03956
Entrez Gene ID: (Human) 4312
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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