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Product Details
PA5-120847
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_0024161)
Conjugate
Form
Liquid
Concentration
3.93 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914419
Product Specific Information
Positive test controls include: BT-474, MCF7, U-251MG, M21. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: PLYNSFTELA QFRLSQDDVN GIQSLYGPPP ASTEEPLVPT KSVPSGSEMP AKCDPALSFD AISTLRGEYL FFKDRYFWRR SHWNPEPEFH LISAFWPSLP SYLDAAYEVN SRDTVFIFKG NEFWAIRGNE VQAGYPRGIH TLGFPPTIRK IDAAVSDKEK KKTYFFAADK YWRFDENSQS MEQGFPRLIA DDFPGVEPKV DAVLQAFGFF YFFSGSSQFE FDPNARMVTH ILKSNSWLHC
Target Information
MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: matrix metallo protease; matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP; MMP-10; MMPs; SL-2; stromelysin 2; Stromelysin-2; Transformation-associated protein 34A; transin 2; Transin-2
Gene Aliases: AV377895; MMP-10; MMP10; SL-2; STMY2
UniProt ID: (Human) P09238, (Mouse) O55123, (Rat) P07152
Entrez Gene ID: (Human) 4319, (Mouse) 17384, (Rat) 117061
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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