Product References
Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signaling.
Archives of pharmacal research
Abdelkader NF,Elbaset MA,Moustafa PE,Ibrahim SM
MA5-13590 was used in Immunohistochemistry to explore the potentiality of the selective sodium-glucose cotransporter-2 inhibitor, empagliflozin (EMPA), to ameliorate streptozotocin-induced DPN in rats with insight into its precise signaling mechanism.
Fri Jul 01 00:00:00 EDT 2022
Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signaling.
Archives of pharmacal research
Abdelkader NF,Elbaset MA,Moustafa PE,Ibrahim SM
MA5-13590 was used in Immunohistochemistry to explore the potentiality of the selective sodium-glucose cotransporter-2 inhibitor, empagliflozin (EMPA), to ameliorate streptozotocin-induced DPN in rats with insight into its precise signaling mechanism.
Fri Jul 01 00:00:00 EDT 2022
TGF-β1/SH2B3 axis regulates anoikis resistance and EMT of lung cancer cells by modulating JAK2/STAT3 and SHP2/Grb2 signaling pathways.
Cell death & disease
Wang LN,Zhang ZT,Wang L,Wei HX,Zhang T,Zhang LM,Lin H,Zhang H,Wang SQ
Published figure using MMP2 monoclonal antibody (Product # MA5-13590) in Western Blot
Thu May 19 00:00:00 EDT 2022
Ozone combined with doxorubicin exerts cytotoxic and anticancer effects on Luminal-A subtype human breast cancer cell line.
Revista da Associacao Medica Brasileira (1992)
Karagulle OO,Yurttas AG
MA5-13590 was used in Immunocytochemistry to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations of doxorubicin in Luminal-A subtype of human breast cancer cell line (MCF-7) and compare the results with effects on L929 fibroblast cell line.
Fri Apr 01 00:00:00 EDT 2022
Inhibition of matrix metalloproteinase-2 modulates malignant behaviour of oral squamous cell carcinoma cells.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Celentano A,Yap T,Paolini R,Yiannis C,Mirams M,Koo K,McCullough M,Cirillo N
MA5-13590 was used in Immunohistochemistry to investigate the effect of matrix metalloproteinases 2 (MMP2) inhibition on oral squamous cell carcinoma activity in vitro and assess MMP2 dysregulation in oral cancer samples.
Mon Mar 01 00:00:00 EST 2021
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis.
Biomedicines
Huang SE,Sulistyowati E,Chao YY,Wu BN,Dai ZK,Hsu JH,Yeh JL
MA5-13590 was used in Western Blot to investigate the in vitro anti-inflammatory and in vivo anti-osteoarthritis effects of KMUP-1.
Fri May 28 00:00:00 EDT 2021
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis.
Biomedicines
Huang SE,Sulistyowati E,Chao YY,Wu BN,Dai ZK,Hsu JH,Yeh JL
MA5-13590 was used in Western Blot to investigate the in vitro anti-inflammatory and in vivo anti-osteoarthritis effects of KMUP-1.
Fri May 28 00:00:00 EDT 2021
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Nature communications
Custers L,Khabirova E,Coorens THH,Oliver TRW,Calandrini C,Young MD,Vieira Braga FA,Ellis P,Mamanova L,Segers H,Maat A,Kool M,Hoving EW,van den Heuvel-Eibrink MM,Nicholson J,Straathof K,Hook L,de Krijger RR,Trayers C,Allinson K,Behjati S,Drost J
MA5-13590 was used in Immunohistochemistry and Immunocytochemistry to indicate that combined HDAC and mTOR inhibition mimic alignant rhabdoid tumour (MRT) differentiation.
Wed Mar 03 00:00:00 EST 2021
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Nature communications
Custers L,Khabirova E,Coorens THH,Oliver TRW,Calandrini C,Young MD,Vieira Braga FA,Ellis P,Mamanova L,Segers H,Maat A,Kool M,Hoving EW,van den Heuvel-Eibrink MM,Nicholson J,Straathof K,Hook L,de Krijger RR,Trayers C,Allinson K,Behjati S,Drost J
MA5-13590 was used in Immunohistochemistry and Immunocytochemistry to indicate that combined HDAC and mTOR inhibition mimic alignant rhabdoid tumour (MRT) differentiation.
Wed Mar 03 00:00:00 EST 2021
Inhibition of Matrix Metalloproteinases and Cancer Cell Detachment by Ru(II) Polypyridyl Complexes Containing 4,7-Diphenyl-1,10-phenanthroline Ligands-New Candidates for Antimetastatic Agents.
Pharmaceuticals (Basel, Switzerland)
Gajda-Morszewski P,Gurgul I,Janczy-Cempa E,Mazuryk O,Łomzik M,Brindell M
MA5-13590 was used in Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot to show a reduction of metastatic cells escaping from the primary lesion to the surrounding tissue by prevention of their detachment and by influencing the activity of MMP-2 and MMP-9.
Fri Oct 01 00:00:00 EDT 2021
Inhibition of Matrix Metalloproteinases and Cancer Cell Detachment by Ru(II) Polypyridyl Complexes Containing 4,7-Diphenyl-1,10-phenanthroline Ligands-New Candidates for Antimetastatic Agents.
Pharmaceuticals (Basel, Switzerland)
Gajda-Morszewski P,Gurgul I,Janczy-Cempa E,Mazuryk O,Łomzik M,Brindell M
MA5-13590 was used in Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot to show a reduction of metastatic cells escaping from the primary lesion to the surrounding tissue by prevention of their detachment and by influencing the activity of MMP-2 and MMP-9.
Fri Oct 01 00:00:00 EDT 2021
Protective Effects of Kuding Tea (Ilex kudingcha C. J. Tseng) Polyphenols on UVB-Induced Skin Aging in SKH1 Hairless Mice.
Molecules (Basel, Switzerland)
Yi R,Zhang J,Sun P,Qian Y,Zhao X
MA5-13590 was used in Western Blotting to study the protective effects of Kuding tea polyphenols on ultraviolet B-induced skin injury of SKH1 hairless mice.
Wed Mar 13 00:00:00 EDT 2019
The expression of two isoforms of matrix metalloproteinase-2 in aged mouse models of diabetes mellitus and chronic kidney disease.
Kidney research and clinical practice
Rhee H,Han M,Kim SS,Kim IY,Lee HW,Bae SS,Ha HK,Jung ES,Lee MY,Seong EY,Lee DW,Lee SB,Lovett DH,Song SH
Published figure using MMP2 monoclonal antibody (Product # MA5-13590) in Immunohistochemistry
Sat Sep 01 00:00:00 EDT 2018
Myofibroblasts from salivary gland adenoid cystic carcinomas promote cancer invasion by expressing MMP2 and CXCL12.
Histopathology
Guan H,Tan J,Zhang F,Gao L,Bai L,Qi D,Dong H,Zhu L,Li X,Liu T
MA5-13590 was used in immunohistochemistry to determine the role of myofibroblasts in salivary gland adenoid cystic carcinoma invasiveness
Fri May 01 00:00:00 EDT 2015
α11β1 integrin-mediated MMP-13-dependent collagen lattice contraction by fibroblasts: evidence for integrin-coordinated collagen proteolysis.
Journal of cellular physiology
Barczyk MM,Lu N,Popova SN,Bolstad AI,Gullberg D
MA5-13590 was used in western blot to study the role of mechanical strain generated by alpha11beta1 integrin in MMP-13-mediated fibroblast collagen lattice remodelling
Wed May 01 00:00:00 EDT 2013
Expression of matrix metalloproteinase-12 is correlated with extracapsular spread of tumor from nodes with metastasis in head and neck squamous cell carcinoma.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Kim JM,Kim HJ,Koo BS,Rha KS,Yoon YH
MA5-13590 was used in immunohistochemistry to study the relationship between expression of MMP-12 in head and neck squamous cell carcinoma primary tumors and extracapsular spread of lymph node metastases
Fri Mar 01 00:00:00 EST 2013
Matrix metalloproteinase, vitamin A and methylprednisolone effects on experimentally induced amyloid arthropathy.
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Sevimli A,Yağcı A,Bülbül A
MA5-13590 was used in immunohistochemistry to study the effects of vitamin A and methylprednisolone on the expression of MMP-1, -2 and -9 in a chick model of amyloid arthropathy
Thu Aug 01 00:00:00 EDT 2013
Induction of pulmonary fibrosis by cerium oxide nanoparticles.
Toxicology and applied pharmacology
Ma JY,Mercer RR,Barger M,Schwegler-Berry D,Scabilloni J,Ma JK,Castranova V
MA5-13590 was used in immunohistochemistry to study the ability of cerium oxide nanoparticles to induce pulmonary fibrosis in a rat model
Wed Aug 01 00:00:00 EDT 2012
MMP-2 expression in 102 patients with glottic laryngeal cancer.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Mallis A,Teymoortash A,Mastronikolis NS,Werner JA,Papadas TA
MA5-13590 was used in immunohistochemistry to study MMP-2 expression in patients with glottic laryngeal cancer and its potential prognostic value
Wed Feb 01 00:00:00 EST 2012
Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.
Ultrastructural pathology
Omran OM,Thabet M
MA5-13590 was used in immunohistochemistry to study the immunohistochemical expression of MMP2 and MMP9 in colorectal cancer in an upper Egypt population
Sun Apr 01 00:00:00 EDT 2012
Down-regulation of matrix metalloproteinase-9 by pyrrolidine dithiocarbamate prevented retinal ganglion cell death after transection of optic nerve in rats.
Current eye research
Sun MH,Chen KJ,Tsao YP,Kao LY,Han WH,Lin KK,Pang JH
MA5-13590 was used in western blot to study the effects of pyrrolidine dithiocarbamate on MMP2 and MMP9 expresssion and MMP-mediated apoptosis in retinal ganglion cells following transection of the optic nerve
Tue Nov 01 00:00:00 EDT 2011
The effects of interferon alpha2b on chemically-induced peritoneal fibrosis and on peritoneal tissue MMP-2 and TIMP-2 levels in rats.
The Journal of international medical research
Ucar E,Borazan A,Semerci E,Binici DN,Yaldiz M,Aysal A,Altug E,Kuvandik C,Huzmeli C,Yetim T,Canda S
MA5-13590 was used in immunohistochemistry to characterize effects of alpha2b treatment on fibrosis and metalloproteinase levels
Thu Jun 03 00:00:00 EDT 2010
SK-PC-B70M confers anti-oxidant activity and reduces Abeta levels in the brain of Tg2576 mice.
Brain research
Seo JS,Kim TK,Leem YH,Lee KW,Park SK,Baek IS,Kim KS,Im GJ,Lee SM,Park YH,Han PL
MA5-13590 was used in western blot to study the effect of an oleanolic-glycoside saponin on anti-oxidant activity and Abeta levels in the brain of Tg2576 mice.
Thu Mar 19 00:00:00 EDT 2009
GSK-3-specific inhibitor-supplemented hESC medium prevents the epithelial-mesenchymal transition process and the up-regulation of matrix metalloproteinases in hESCs cultured in feeder-free conditions.
Molecular human reproduction
Ullmann U,Gilles C,De Rycke M,Van de Velde H,Sermon K,Liebaers I
MA5-13590 was used in immunocytochemistry to investigate the effect of an inhibitor against GSK-3 on the epithelial-mesenchymal transition process and the maintenance of th pluripotency of stem cells
Sat Mar 01 00:00:00 EST 2008
Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARgamma Dependent and Independent Mechanisms.
PPAR research
He Q,Pang R,Song X,Chen J,Chen H,Chen B,Hu P,Chen M
MA5-13590 was used in western blot to investigate the effect of rosiglitazone on SGC-7901 gastric cancer cells and its mechanism
Thu Jul 14 00:00:00 EDT 2011
The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases.
International journal of cancer
Ou DP,Tao YM,Tang FQ,Yang LY
MA5-13590 was used in western blot to examine the effect of hepatitis B virus X protein on hepatocellular carcinoma metastasis
Thu Mar 15 00:00:00 EDT 2007
Matrix metalloproteinase induction in fibrosis and fibrotic nodule formation due to silica inhalation.
American journal of physiology. Lung cellular and molecular physiology
Scabilloni JF,Wang L,Antonini JM,Roberts JR,Castranova V,Mercer RR
MA5-13590 was used in immunohistochemistry to study fibrosis and fibrotic nodule formation following silica inhalation and the role of MMPs
Fri Apr 01 00:00:00 EST 2005
Cardiac morphogenesis: matrix metalloproteinase coordination of cellular mechanisms underlying heart tube formation and directionality of looping.
Developmental dynamics : an official publication of the American Association of Anatomists
Linask KK,Han M,Cai DH,Brauer PR,Maisastry SM
MA5-13590 was used in blocking or activating experiment to study the role of MMPs in cardiac morphogenesis
Fri Jul 01 00:00:00 EDT 2005
Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease.
Gut
Kirkegaard T,Hansen A,Bruun E,Brynskov J
MA5-13590 was used in immunohistochemistry to investigate the expression and the role of matrix metalloproteinases in intestinal fistulae
Sat May 01 00:00:00 EDT 2004
Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease.
Gut
Kirkegaard T,Hansen A,Bruun E,Brynskov J
MA5-13590 was used in immunohistochemistry to investigate the expression and the role of matrix metalloproteinases in intestinal fistulae
Sat May 01 00:00:00 EDT 2004
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research
Pellikainen JM,Ropponen KM,Kataja VV,Kellokoski JK,Eskelinen MJ,Kosma VM
MA5-13590 was used in immunohistochemistry to study the prognostic value of MMP2 and MMP9 in breast cancer and their relationship to activator protein-2 and HER2
Mon Nov 15 00:00:00 EST 2004
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
American journal of obstetrics and gynecology
Gaiotto MA,Focchi J,Ribalta JL,Stávale JN,Baracat EC,Lima GR,Guerreiro da Silva ID
MA5-13590 was used in immunohistochemistry to study the expression of MMP-2 in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma
Sat May 01 00:00:00 EDT 2004
A comparative study of MMP-2 in vulvar neoplasms.
Gynecologic oncology
Bovo AC,da Silva ID,Takita LC,Fochi J,Stávale JN,Marks G,de Lima GR
MA5-13590 was used in immunohistochemistry to study MMP-2 protein expressin in various vulvar neoplasms
Sat May 01 00:00:00 EDT 2004
Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis.
Acta neuropathologica
Miao Q,Baumgärtner W,Failing K,Alldinger S
MA5-13590 was used in immunohistochemistry to study the phase-dependent expression of MMPs and TIMPs in demyelinating canine distemper encephalitis
Sat Nov 01 00:00:00 EST 2003
Derivation and characterization of a Wilms' tumour cell line, WiT 49.
International journal of cancer
Alami J,Williams BR,Yeger H
MA5-13590 was used in western blot to derive and characterize a Wilms' tumour cell line
Mon Nov 10 00:00:00 EST 2003
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin.
Journal of immunology (Baltimore, Md. : 1950)
Ratzinger G,Stoitzner P,Ebner S,Lutz MB,Layton GT,Rainer C,Senior RM,Shipley JM,Fritsch P,Schuler G,Romani N
MA5-13590 was used in blocking or activating experiment to study the role of MMP2 and MMP9 in the migration of Langerhans cells and dermal dendritic cells from skin
Wed May 01 00:00:00 EDT 2002