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Product Details
PA5-28076
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
Bovine
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 205 and 267 of Human MMP7
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545552
Product Specific Information
Recommended positive controls: A549.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HGNC:7174; Matrilysin; matrilysin, uterine; Matrin; matrix metallo protease; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); Matrix metalloproteinase-7; MMP; MMP 7; MMP-7; MMPs; PUMP 1; Pump 1 protease; Pump-1 protease; uterine matrilysin; Uterine metalloproteinase
Gene Aliases: MAT; MMP-7; MMP7; MPMM; MPSL1; PUMP-1; PUMP1
UniProt ID: (Human) P09237, (Rat) P50280
Entrez Gene ID: (Human) 4316, (Bovine) 286794, (Rat) 25335, (Mouse) 17393
proteolysis
aging
extracellular matrix disassembly
collagen catabolic process
response to nutrient levels
estrous cycle
maternal process involved in female pregnancy
cellular response to mechanical stimulus
antibacterial peptide secretion
antibacterial peptide biosynthetic process
regulation of cell proliferation
response to drug
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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