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Specificity: Human MOG
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: DAQB-92E24.2; MGC26137; MOG alpha 6; MOG alpha-5; MOG alpha-6; MOG AluA; MOG AluB; MOG Ig AluB; MOG Ig-AluB; MOGIG-2; Myelin-oligodendrocyte glycoprotein
Gene Aliases: BTN6; BTNL11; MOG; MOGIG2; NRCLP7
UniProt ID: (Human) A6NNJ9
Entrez Gene ID: (Human) 4340
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