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Invitrogen
MPST Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-51548
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MPST. Recombinant protein control fragment (Product #RP-91349).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644090
Product Specific Information
Immunogen sequence: AVSLLDGGLR HWLRQNLPLS SGKSQPAPAE FRAQLDPAFI KTYEDIKENL ESRRFQVVDS RATGRFRGTE PEPRDGIEPG HIPGTVNIPF TDFLSQEGLE KSPEEIRHLF QEKKVDLSKP LVATCGSGVT ACHVALGAYL CGKPD
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.
Target Information
This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; MST; testicular tissue protein Li 200; tRNA thiouridin modification protein 1
Gene Aliases: MPST; MST; TST2; TUM1
UniProt ID: (Human) P25325
Entrez Gene ID: (Human) 4357
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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