Product References
Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease.
Human molecular genetics
Amarasekera SSC,Hock DH,Lake NJ,Calvo SE,Grønborg SW,Krzesinski EI,Amor DJ,Fahey MC,Simons C,Wibrand F,Mootha VK,Lek M,Lunke S,Stark Z,Østergaard E,Christodoulou J,Thorburn DR,Stroud DA,Compton AG
Thu Jul 20 00:00:00 EDT 2023
Deficiency of the mitochondrial ribosomal subunit, MRPL50, causes autosomal recessive syndromic premature ovarian insufficiency.
Human genetics
Bakhshalizadeh S,Hock DH,Siddall NA,Kline BL,Sreenivasan R,Bell KM,Casagranda F,Kamalanathan S,Sahoo J,Narayanan N,Naik D,Suryadevara V,Compton AG,Amarasekera SSC,Kapoor R,Jaillard S,Simpson A,Robevska G,van den Bergen J,Pachernegg S,Ayers KL,Thorburn DR,Stroud DA,Hime GR,Sinclair AH,Tucker EJ
Sat Jul 01 00:00:00 EDT 2023
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Serine palmitoyltransferase assembles at ER-mitochondria contact sites.
Life science alliance
Aaltonen MJ,Alecu I,König T,Bennett SA,Shoubridge EA
Tue Feb 01 00:00:00 EST 2022
Pentatricopeptide Protein PTCD2 Regulates COIII Translation in Mitochondria of the HeLa Cell Line.
International journal of molecular sciences
Baleva MV,Chicherin I,Piunova U,Zgoda V,Patrushev MV,Levitskii S,Kamenski P
Thu Nov 17 00:00:00 EST 2022
Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan.
Aging cell
Richman TR,Ermer JA,Siira SJ,Kuznetsova I,Brosnan CA,Rossetti G,Baker J,Perks KL,Cserne Szappanos H,Viola HM,Gray N,Larance M,Hool LC,Zuryn S,Rackham O,Filipovska A
Thu Jul 01 00:00:00 EDT 2021
Linear Density Sucrose Gradients to Study Mitoribosomal Biogenesis in Tissue-Specific Knockout Mice.
Methods in molecular biology (Clifton, N.J.)
Ruzzenente B,Metodiev MD
Thu Apr 01 00:00:00 EDT 2021
Uniparental isodisomy of chromosome 2 causing MRPL44-related multisystem mitochondrial disease.
Molecular biology reports
Horga A,Manole A,Mitchell AL,Bugiardini E,Hargreaves IP,Mowafi W,Bettencourt C,Blakely EL,He L,Polke JM,Woodward CE,Dalla Rosa I,Shah S,Pittman AM,Quinlivan R,Reilly MM,Taylor RW,Holt IJ,Hanna MG,Pitceathly RDS,Spinazzola A,Houlden H
Mon Mar 01 00:00:00 EST 2021
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Nucleic acids research
Meng F,Zhou M,Xiao Y,Mao X,Zheng J,Lin J,Lin T,Ye Z,Cang X,Fu Y,Wang M,Guan MX
Mon Jan 25 00:00:00 EST 2021
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
Nature cell biology
König T,Nolte H,Aaltonen MJ,Tatsuta T,Krols M,Stroh T,Langer T,McBride HM
Wed Dec 01 00:00:00 EST 2021
Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses.
Genomics, proteomics & bioinformatics
Shi R,Feng Z,Zhang X
Fri Oct 01 00:00:00 EDT 2021
An in vitro system to silence mitochondrial gene expression.
Cell
Cruz-Zaragoza LD,Dennerlein S,Linden A,Yousefi R,Lavdovskaia E,Aich A,Falk RR,Gomkale R,Schöndorf T,Bohnsack MT,Richter-Dennerlein R,Urlaub H,Rehling P
Thu Nov 11 00:00:00 EST 2021
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis.
Journal of cell science
Lee RG,Gao J,Siira SJ,Shearwood AM,Ermer JA,Hofferek V,Mathews JC,Zheng M,Reid GE,Rackham O,Filipovska A
Fri Jul 24 00:00:00 EDT 2020
Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation.
Cell reports
Schneider K,Nelson GM,Watson JL,Morf J,Dalglish M,Luh LM,Weber A,Bertolotti A
Tue Sep 15 00:00:00 EDT 2020
A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement.
Human molecular genetics
Jackson CB,Huemer M,Bolognini R,Martin F,Szinnai G,Donner BC,Richter U,Battersby BJ,Nuoffer JM,Suomalainen A,Schaller A
Fri Feb 15 00:00:00 EST 2019
A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement.
Human molecular genetics
Jackson CB,Huemer M,Bolognini R,Martin F,Szinnai G,Donner BC,Richter U,Battersby BJ,Nuoffer JM,Suomalainen A,Schaller A
Fri Feb 15 00:00:00 EST 2019
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
Human molecular genetics
Pulman J,Ruzzenente B,Bianchi L,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD
Wed May 01 00:00:00 EDT 2019
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
Human molecular genetics
Pulman J,Ruzzenente B,Bianchi L,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD
Wed May 01 00:00:00 EDT 2019
Fidelity of translation initiation is required for coordinated respiratory complex assembly.
Science advances
Rudler DL,Hughes LA,Perks KL,Richman TR,Kuznetsova I,Ermer JA,Abudulai LN,Shearwood AJ,Viola HM,Hool LC,Siira SJ,Rackham O,Filipovska A
Sun Dec 01 00:00:00 EST 2019
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.
The EMBO journal
Ferreira N,Perks KL,Rossetti G,Rudler DL,Hughes LA,Ermer JA,Scott LH,Kuznetsova I,Richman TR,Narayana VK,Abudulai LN,Shearwood AJ,Cserne Szappanos H,Tull D,Yeoh GC,Hool LC,Filipovska A,Rackham O
Mon Dec 16 00:00:00 EST 2019
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
Nucleic acids research
Lavdovskaia E,Kolander E,Steube E,Mai MM,Urlaub H,Richter-Dennerlein R
Wed Sep 19 00:00:00 EDT 2018
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
Nucleic acids research
Lavdovskaia E,Kolander E,Steube E,Mai MM,Urlaub H,Richter-Dennerlein R
Wed Sep 19 00:00:00 EDT 2018
Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z.
EMBO reports
Siira SJ,Rossetti G,Richman TR,Perks K,Ermer JA,Kuznetsova I,Hughes L,Shearwood AJ,Viola HM,Hool LC,Rackham O,Filipovska A
Mon Oct 01 00:00:00 EDT 2018
Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z.
EMBO reports
Siira SJ,Rossetti G,Richman TR,Perks K,Ermer JA,Kuznetsova I,Hughes L,Shearwood AJ,Viola HM,Hool LC,Rackham O,Filipovska A
Mon Oct 01 00:00:00 EDT 2018
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.
EMBO reports
Antonicka H,Choquet K,Lin ZY,Gingras AC,Kleinman CL,Shoubridge EA
Sun Jan 01 00:00:00 EST 2017
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.
EMBO reports
Antonicka H,Choquet K,Lin ZY,Gingras AC,Kleinman CL,Shoubridge EA
Sun Jan 01 00:00:00 EST 2017
Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Science advances
Perks KL,Ferreira N,Richman TR,Ermer JA,Kuznetsova I,Shearwood AJ,Lee RG,Viola HM,Johnstone VPA,Matthews V,Hool LC,Rackham O,Filipovska A
Tue Aug 01 00:00:00 EDT 2017
Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Science advances
Perks KL,Ferreira N,Richman TR,Ermer JA,Kuznetsova I,Shearwood AJ,Lee RG,Viola HM,Johnstone VPA,Matthews V,Hool LC,Rackham O,Filipovska A
Tue Aug 01 00:00:00 EDT 2017
Stomatin-like protein 2 deficiency results in impaired mitochondrial translation.
PloS one
Mitsopoulos P,Lapohos O,Weraarpachai W,Antonicka H,Chang YH,Madrenas J
Wed Sep 20 00:00:00 EDT 2017
Stomatin-like protein 2 deficiency results in impaired mitochondrial translation.
PloS one
Mitsopoulos P,Lapohos O,Weraarpachai W,Antonicka H,Chang YH,Madrenas J
Wed Sep 20 00:00:00 EDT 2017
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals.
eLife
Kühl I,Miranda M,Atanassov I,Kuznetsova I,Hinze Y,Mourier A,Filipovska A,Larsson NG
Tue Nov 14 00:00:00 EST 2017
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals.
eLife
Kühl I,Miranda M,Atanassov I,Kuznetsova I,Hinze Y,Mourier A,Filipovska A,Larsson NG
Tue Nov 14 00:00:00 EST 2017
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.
Nature communications
Richman TR,Spåhr H,Ermer JA,Davies SM,Viola HM,Bates KA,Papadimitriou J,Hool LC,Rodger J,Larsson NG,Rackham O,Filipovska A
Mon Jun 20 00:00:00 EDT 2016
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.
Nature communications
Richman TR,Spåhr H,Ermer JA,Davies SM,Viola HM,Bates KA,Papadimitriou J,Hool LC,Rodger J,Larsson NG,Rackham O,Filipovska A
Mon Jun 20 00:00:00 EDT 2016
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Cell reports
Rackham O,Busch JD,Matic S,Siira SJ,Kuznetsova I,Atanassov I,Ermer JA,Shearwood AM,Richman TR,Stewart JB,Mourier A,Milenkovic D,Larsson NG,Filipovska A
Tue Aug 16 00:00:00 EDT 2016
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Cell reports
Rackham O,Busch JD,Matic S,Siira SJ,Kuznetsova I,Atanassov I,Ermer JA,Shearwood AM,Richman TR,Stewart JB,Mourier A,Milenkovic D,Larsson NG,Filipovska A
Tue Aug 16 00:00:00 EDT 2016
Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.
The Journal of cell biology
Richter U,Lahtinen T,Marttinen P,Suomi F,Battersby BJ
Mon Oct 26 00:00:00 EDT 2015
Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.
The Journal of cell biology
Richter U,Lahtinen T,Marttinen P,Suomi F,Battersby BJ
Mon Oct 26 00:00:00 EDT 2015
Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction.
PLoS genetics
Richman TR,Ermer JA,Davies SM,Perks KL,Viola HM,Shearwood AM,Hool LC,Rackham O,Filipovska A
Sun Mar 01 00:00:00 EST 2015
Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction.
PLoS genetics
Richman TR,Ermer JA,Davies SM,Perks KL,Viola HM,Shearwood AM,Hool LC,Rackham O,Filipovska A
Sun Mar 01 00:00:00 EST 2015
Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis.
Cell reports
Antonicka H,Shoubridge EA
Tue Feb 17 00:00:00 EST 2015
Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis.
Cell reports
Antonicka H,Shoubridge EA
Tue Feb 17 00:00:00 EST 2015
A Role for the Mitochondrial Protein Mrpl44 in Maintaining OXPHOS Capacity.
PloS one
Yeo JH,Skinner JP,Bird MJ,Formosa LE,Zhang JG,Kluck RM,Belz GT,Chong MM
Fri May 13 00:00:00 EDT 2016
A Role for the Mitochondrial Protein Mrpl44 in Maintaining OXPHOS Capacity.
PloS one
Yeo JH,Skinner JP,Bird MJ,Formosa LE,Zhang JG,Kluck RM,Belz GT,Chong MM
Fri May 13 00:00:00 EDT 2016
A Role for the Mitochondrial Protein Mrpl44 in Maintaining OXPHOS Capacity.
PloS one
Yeo JH,Skinner JP,Bird MJ,Formosa LE,Zhang JG,Kluck RM,Belz GT,Chong MM
Fri May 13 00:00:00 EDT 2016
A Role for the Mitochondrial Protein Mrpl44 in Maintaining OXPHOS Capacity.
PloS one
Yeo JH,Skinner JP,Bird MJ,Formosa LE,Zhang JG,Kluck RM,Belz GT,Chong MM
Fri May 13 00:00:00 EDT 2016
A bifunctional protein regulates mitochondrial protein synthesis.
Nucleic acids research
Richman TR,Davies SM,Shearwood AM,Ermer JA,Scott LH,Hibbs ME,Rackham O,Filipovska A
Thu May 01 00:00:00 EDT 2014
A bifunctional protein regulates mitochondrial protein synthesis.
Nucleic acids research
Richman TR,Davies SM,Shearwood AM,Ermer JA,Scott LH,Hibbs ME,Rackham O,Filipovska A
Thu May 01 00:00:00 EDT 2014
The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.
Cell metabolism
Antonicka H,Sasarman F,Nishimura T,Paupe V,Shoubridge EA
Tue Mar 05 00:00:00 EST 2013
The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.
Cell metabolism
Antonicka H,Sasarman F,Nishimura T,Paupe V,Shoubridge EA
Tue Mar 05 00:00:00 EST 2013
Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy.
Journal of medical genetics
Carroll CJ,Isohanni P,Pöyhönen R,Euro L,Richter U,Brilhante V,Götz A,Lahtinen T,Paetau A,Pihko H,Battersby BJ,Tyynismaa H,Suomalainen A
Fri Mar 01 00:00:00 EST 2013
Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy.
Journal of medical genetics
Carroll CJ,Isohanni P,Pöyhönen R,Euro L,Richter U,Brilhante V,Götz A,Lahtinen T,Paetau A,Pihko H,Battersby BJ,Tyynismaa H,Suomalainen A
Fri Mar 01 00:00:00 EST 2013
