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Product Details
25990-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MTMR7 Fusion Protein Ag23170 (514-660 aa encoded by BC130577)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RQSVTDYLM AVKEETQQLE EELEALEERL EKIQKVQLNC TKVKSKQSEP SKHSGFSTSD NSIANTPQDY SGNMKSFPSR SPSQGDEDSA LILTQDNLKS SDPDLSANSD QESGVEDLSC RSPSGGEHAP SEDSGKDRDS DEAVFLTA (514-660 aa encoded by BC130577)
Target Information
This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1, 3-bisphosphate. A pseudogene of this gene is found on chromosome 5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781E194; Inositol 1,3-bisphosphate phosphatase; MGC163449; MGC163451; Myotubularin-related protein 7; Phosphatidylinositol-3-phosphate phosphatase MTMR7
Gene Aliases: MTMR7
UniProt ID: (Human) Q9Y216, (Mouse) Q9Z2C9
Entrez Gene ID: (Human) 9108, (Mouse) 54384, (Rat) 306490
phosphatidylinositol-3-phosphatase activity
protein tyrosine phosphatase activity
protein binding
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine/threonine phosphatase activity
JUN kinase phosphatase activity
phosphohistidine phosphatase activity
inositol bisphosphate phosphatase activity
hydrolase activity
phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
inositol-1,3,4-trisphosphate 4-phosphatase activity
NADP phosphatase activity
transmembrane receptor protein phosphatase activity
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
inositol-4,5-bisphosphate 5-phosphatase activity
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
inositol phosphate phosphatase activity
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
inositol-3,4-bisphosphate 4-phosphatase activity
inositol-1,3,4-trisphosphate 1-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity
IDP phosphatase activity
phosphatase
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