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MUC2 Antibody (PA5-103083) in ICC/IF
Immunofluorescent analysis of MUC2 in SW480 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with MUC2 polyclonal antibody (Product # PA5-103083) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-103083
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MUC2(Accession Q02817), corresponding to amino acid residues T594-V644.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852453
Product Specific Information
Antibody detects endogenous levels of total MUC2.
Target Information
Secreted epithelial mucins are large macromolecules which exhibit extreme polydispersity. Mucin 2 is the major intestinal mucin. O-glycans are attached to MUC2 in a potentially diverse arrangement, which is crucial for their interaction with endogeneous and exogeneous lectins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: colonic mucin; Intestinal mucin-2; MCM; MUC-2; muc2; mucin 2, intestinal/tracheal; Mucin-2; mucin-like protein; secreted gel-forming mucin
Gene Aliases: 2010015E03Rik; HH-Muc; MCM; MLP; MUC-2; MUC2; SMUC; wnn
UniProt ID: (Human) Q02817
Entrez Gene ID: (Human) 4583, (Rat) 24572, (Mouse) 17831
O-glycan processing
maintenance of gastrointestinal epithelium
epithelial cell development
apoptotic process
negative regulation of cell proliferation
response to hormone
negative regulation of cell migration
response to lipopolysaccharide
response to vitamin A
positive regulation of apoptotic process
cellular response to tumor necrosis factor
response to transforming growth factor beta
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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