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MUC2 Antibody (PA5-79702) in IHC (P)
Immunohistochemical analysis of MUC2 in paraffin-embedded section of human intestine cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 5μg/mL rabbit anti-MUC2 antibody (Product # PA5-79702) overnight at 4°C. DyLight®488 Conjugated Goat Ant... View More
Product Details
PA5-79702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Horse,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human MUC2 (DDFKTASGLVEATGAGFANTWKAQSTCHDKLDWLDD).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2746817
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Secreted epithelial mucins are large macromolecules which exhibit extreme polydispersity. Mucin 2 is the major intestinal mucin. O-glycans are attached to MUC2 in a potentially diverse arrangement, which is crucial for their interaction with endogeneous and exogeneous lectins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: colonic mucin; Intestinal mucin-2; MCM; MUC-2; muc2; mucin 2, intestinal/tracheal; Mucin-2; mucin-like protein; secreted gel-forming mucin
Gene Aliases: 2010015E03Rik; HH-Muc; MCM; MLP; MUC-2; MUC2; SMUC; wnn
UniProt ID: (Human) Q02817
Entrez Gene ID: (Human) 4583, (Rat) 24572, (Mouse) 17831
O-glycan processing
maintenance of gastrointestinal epithelium
epithelial cell development
apoptotic process
negative regulation of cell proliferation
response to hormone
negative regulation of cell migration
response to lipopolysaccharide
response to vitamin A
positive regulation of apoptotic process
cellular response to tumor necrosis factor
response to transforming growth factor beta
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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