Product References
A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases.
The European respiratory journal
Addante A,Raymond W,Gitlin I,Charbit A,Orain X,Scheffler AW,Kuppe A,Duerr J,Daniltchenko M,Drescher M,Graeber SY,Healy AM,Oscarson S,Fahy JV,Mall MA
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Mon May 01 00:00:00 EDT 2023
Inhibition of microRNA-328 Increases Ocular Mucin Expression and Conjunctival Goblet Cells.
Biomedicines
Choo J,Liao CH,Tseng CL,Chen JL,Cheng HC,Liang CL,Juo SH
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Thu Jan 19 00:00:00 EST 2023
Construction of Human Three-Dimensional Lung Model Using Layer-by-Layer Method.
Tissue engineering. Part C, Methods
Akamatsu Y,Akagi T,Sumitomo T,Takahara Y,Akiyama S,Kawabata S,Akashi M
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Wed Mar 01 00:00:00 EST 2023
Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp).
Journal of medical virology
Meng W,Guo S,Cao S,Shuda M,Robinson-McCarthy LR,McCarthy KR,Shuda Y,Paniz Mondolfi AE,Bryce C,Grimes Z,Sordillo EM,Cordon-Cardo C,Li P,Zhang H,Perlman S,Guo H,Gao SJ,Chang Y,Moore PS
MA5-12178 was used in Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin) to suggest that NSP12 may have diminished steady-state expression or extensive posttranslation modifications that limit antibody reactivity during SARS-CoV-2 replication.
Sun Jan 01 00:00:00 EST 2023
Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp).
Journal of medical virology
Meng W,Guo S,Cao S,Shuda M,Robinson-McCarthy LR,McCarthy KR,Shuda Y,Paniz Mondolfi AE,Bryce C,Grimes Z,Sordillo EM,Cordon-Cardo C,Li P,Zhang H,Perlman S,Guo H,Gao SJ,Chang Y,Moore PS
MA5-12178 was used in Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin) to suggest that NSP12 may have diminished steady-state expression or extensive posttranslation modifications that limit antibody reactivity during SARS-CoV-2 replication.
Sun Jan 01 00:00:00 EST 2023
Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp).
Journal of medical virology
Meng W,Guo S,Cao S,Shuda M,Robinson-McCarthy LR,McCarthy KR,Shuda Y,Paniz Mondolfi AE,Bryce C,Grimes Z,Sordillo EM,Cordon-Cardo C,Li P,Zhang H,Perlman S,Guo H,Gao SJ,Chang Y,Moore PS
MA5-12178 was used in Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin) to suggest that NSP12 may have diminished steady-state expression or extensive posttranslation modifications that limit antibody reactivity during SARS-CoV-2 replication.
Sun Jan 01 00:00:00 EST 2023
Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma.
Cell genomics
Koh KD,Bonser LR,Eckalbar WL,Yizhar-Barnea O,Shen J,Zeng X,Hargett KL,Sun DI,Zlock LT,Finkbeiner WE,Ahituv N,Erle DJ
MA5-12178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin) to provide a catalog of cell type-specific genes and regulatory elements involved in IL-13 bronchial epithelial response and showcases their use for therapeutic purposes.
Wed Jan 11 00:00:00 EST 2023
Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.
International journal of molecular sciences
Baumlin N,Silswal N,Dennis JS,Niloy AJ,Kim MD,Salathe M
MA5-12178 was used in Immunocytochemistry-immunofluorescence to test the effects of menthol on parameters of mucociliary clearance (MCC) in air-liquid interface (ALI) cultures of primary airway epithelial cells.
Sun Jan 15 00:00:00 EST 2023
Full thickness 3D in vitro conjunctiva model enables goblet cell differentiation.
Scientific reports
Schwebler J,Fey C,Kampik D,Lotz C
MA5-12178 was used in Immunohistochemistry to develop a full thickness in vitro conjunctiva model that includes a multi-layer epithelium and mucus-secreting goblet cells.
Fri Jul 28 00:00:00 EDT 2023
A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution.
Respiratory research
Prescott RA,Pankow AP,de Vries M,Crosse KM,Patel RS,Alu M,Loomis C,Torres V,Koralov S,Ivanova E,Dittmann M,Rosenberg BR
MA5-12178 was used in Immunohistochemistry-immunofluorescence to support BCi-NS1.1-derived HAE cultures as a valuable tool for the study of airway infectious disease.
Mon Aug 28 00:00:00 EDT 2023
A high-throughput cigarette smoke-treated bronchosphere model for disease-relevant phenotypic compound screening.
PloS one
Beri P,Woo YJ,Schierenbeck K,Chen K,Barnes SW,Ross O,Krutil D,Quackenbush D,Fang B,Walker J,Barnes W,Toyama EQ
MA5-12178 was used in Immunocytochemistry-immunofluorescence to provide insight into the utility of this bronchopshere model to examine human respiratory disease impacted by CSE exposure and the ability to screen for therapeutics to reverse the pathogenic changes caused by CSE.
Mon Jul 03 00:00:00 EDT 2023
Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
The EMBO journal
Wizenty J,Müllerke S,Kolesnichenko M,Heuberger J,Lin M,Fischer AS,Mollenkopf HJ,Berger H,Tacke F,Sigal M
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry (Paraffin)
Mon Jul 04 00:00:00 EDT 2022
Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells.
PLoS biology
Zhu Y,Chew KY,Wu M,Karawita AC,McCallum G,Steele LE,Yamamoto A,Labzin LI,Yarlagadda T,Khromykh AA,Wang X,Sng JDJ,Stocks CJ,Xia Y,Kollmann TR,Martino D,Joensuu M,Meunier FA,Balistreri G,Bielefeldt-Ohmann H,Bowen AC,Kicic A,Sly PD,Spann KM,Short KR
MA5-12178 was used in Immunocytochemistry-immunoflourescence to show that the nasal epithelium of children supports lower infection and replication of ancestral SARS-CoV-2, although this may be changing as the virus evolves.
Mon Aug 01 00:00:00 EDT 2022
Age-Related Differences in Structure and Function of Nasal Epithelial Cultures From Healthy Children and Elderly People.
Frontiers in immunology
Balázs A,Millar-Büchner P,Mülleder M,Farztdinov V,Szyrwiel L,Addante A,Kuppe A,Rubil T,Drescher M,Seidel K,Stricker S,Eils R,Lehmann I,Sawitzki B,Röhmel J,Ralser M,Mall MA
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Mon May 02 00:00:00 EDT 2022
Age-Related Differences in Structure and Function of Nasal Epithelial Cultures From Healthy Children and Elderly People.
Frontiers in immunology
Balázs A,Millar-Büchner P,Mülleder M,Farztdinov V,Szyrwiel L,Addante A,Kuppe A,Rubil T,Drescher M,Seidel K,Stricker S,Eils R,Lehmann I,Sawitzki B,Röhmel J,Ralser M,Mall MA
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Mon May 02 00:00:00 EDT 2022
Jian-Pi-Yi-Qi-Fang ameliorates chronic atrophic gastritis in rats through promoting the proliferation and differentiation of gastric stem cells.
Annals of translational medicine
Wang P,Xu T,Yan Z,Zheng X,Zhu F
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Jian-Pi-Yi-Qi-Fang ameliorates chronic atrophic gastritis in rats through promoting the proliferation and differentiation of gastric stem cells.
Annals of translational medicine
Wang P,Xu T,Yan Z,Zheng X,Zhu F
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis.
Nature communications
Aguilar C,Pauzuolis M,Pompaiah M,Vafadarnejad E,Arampatzi P,Fischer M,Narres D,Neyazi M,Kayisoglu Ö,Sell T,Blüthgen N,Morkel M,Wiegering A,Germer CT,Kircher S,Rosenwald A,Saliba AE,Bartfeld S
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Wed Oct 05 00:00:00 EDT 2022
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis.
Nature communications
Aguilar C,Pauzuolis M,Pompaiah M,Vafadarnejad E,Arampatzi P,Fischer M,Narres D,Neyazi M,Kayisoglu Ö,Sell T,Blüthgen N,Morkel M,Wiegering A,Germer CT,Kircher S,Rosenwald A,Saliba AE,Bartfeld S
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Wed Oct 05 00:00:00 EDT 2022
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis.
Nature communications
Aguilar C,Pauzuolis M,Pompaiah M,Vafadarnejad E,Arampatzi P,Fischer M,Narres D,Neyazi M,Kayisoglu Ö,Sell T,Blüthgen N,Morkel M,Wiegering A,Germer CT,Kircher S,Rosenwald A,Saliba AE,Bartfeld S
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Western Blot
Wed Oct 05 00:00:00 EDT 2022
Quantifying Intracellular Viral Pathogen: Specimen Preparation, Visualization and Quantification of Multiple Immunofluorescent Signals in Fixed Human Airway Epithelium Cultured at Air-Liquid Interface.
Journal of personalized medicine
Wong SL,Pandzic E,Kardia E,Allan KM,Whan RM,Waters SA
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Fri Oct 07 00:00:00 EDT 2022
Quantifying Intracellular Viral Pathogen: Specimen Preparation, Visualization and Quantification of Multiple Immunofluorescent Signals in Fixed Human Airway Epithelium Cultured at Air-Liquid Interface.
Journal of personalized medicine
Wong SL,Pandzic E,Kardia E,Allan KM,Whan RM,Waters SA
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Fri Oct 07 00:00:00 EDT 2022
Acute infection with Brachyspira hyodysenteriae affects mucin expression, glycosylation, and fecal MUC5AC.
Frontiers in cellular and infection microbiology
Lin SJ,Helm ET,Gabler NK,Burrough ER
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Tue Feb 28 00:00:00 EST 2023
Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures.
Life science alliance
Guo W,Porter LM,Crozier TW,Coates M,Jha A,McKie M,Nathan JA,Lehner PJ,Greenwood EJ,McCaughan F
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Fri Apr 01 00:00:00 EDT 2022
Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures.
Life science alliance
Guo W,Porter LM,Crozier TW,Coates M,Jha A,McKie M,Nathan JA,Lehner PJ,Greenwood EJ,McCaughan F
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Fri Apr 01 00:00:00 EDT 2022
The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.
PLoS pathogens
Holubova J,Stanek O,Juhasz A,Hamidou Soumana I,Makovicky P,Sebo P
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Fri Apr 01 00:00:00 EDT 2022
Pharmacological OGG1 inhibition decreases murine allergic airway inflammation.
Frontiers in pharmacology
Tanner L,Bergwik J,Bhongir RKV,Pan L,Dong C,Wallner O,Kalderén C,Helleday T,Boldogh I,Adner M,Egesten A
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Fri Nov 04 00:00:00 EDT 2022
Substance P/neurokinin-1 receptor pathway blockade ameliorates limbal stem cell deficiency by modulating mTOR pathway and preventing cell senescence.
Stem cell reports
Lasagni Vitar R,Triani F,Barbariga M,Fonteyne P,Rama P,Ferrari G
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Tue Apr 12 00:00:00 EDT 2022
CTNNAL1 participates in the regulation of mucus overproduction in HDM-induced asthma mouse model through the YAP-ROCK2 pathway.
Journal of cellular and molecular medicine
Wu D,Jiang W,Liu C,Liu L,Li F,Ma X,Pan L,Liu C,Qu X,Liu H,Qin X,Xiang Y
MA5-12178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin) to demonstrate that CTNNAL1 plays an important role in HDM-induced asthma, mediating mucus secretion through the YAP-ROCK2 pathway.
Tue Mar 01 00:00:00 EST 2022
Reconstituted basement membrane enables airway epithelium modeling and nanoparticle toxicity testing.
International journal of biological macromolecules
Rofaani E,Huang B,Liang F,Peng J,Chen Y
MA5-12178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin) to generate airway epithelium by using such an artificial basement membrane (ABM) and human-induced pluripotent stem cells (hiPSCs).
Fri Apr 15 00:00:00 EDT 2022
Engineering rotating apical-out airway organoid for assessing respiratory cilia motility.
iScience
Wijesekara P,Yadav P,Perkins LA,Stolz DB,Franks JM,Watkins SC,Reinoso Jacome E,Brody SL,Horani A,Xu J,Barati Farimani A,Ren X
MA5-12178 was used in Immunohistochemistry to describe a robust approach for reproducible engineering of apical-out airway organoid (AOAO) from a defined number of cells.
Fri Aug 19 00:00:00 EDT 2022
Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models.
Disease models & mechanisms
Jeong H,Woo Lee Y,Park IH,Noh H,Kim SH,Kim J,Jeon D,Jang HJ,Oh J,On D,Uhm C,Cho K,Oh H,Yoon S,Seo JS,Kim JJ,Seok SH,Lee YJ,Hong SM,An SH,Yeon Kim S,Kim YB,Hwang JY,Lee HJ,Kim HB,Jeong DG,Song D,Song M,Park MS,Choi KS,Park JW,Seo JY,Yun JW,Shin JS,Lee HY,Nam KT,Seong JK
MA5-12178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin) to provide comprehensive insights into the pathogenic spectrum of COVID-19 using preclinical models.
Tue Nov 01 00:00:00 EDT 2022
Quantification of increased MUC5AC expression in airway mucus of smoker using an automated image-based approach.
Microscopy research and technique
Groiss S,Somvilla I,Daxböck C,Fuchs J,Lang-Olip I,Stiegler P,Leber B,Liegl-Atzwanger B,Brislinger D
MA5-12178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin) to present a simple, image-based, and high-processing computational method that allows determining the ratio of MUC5AC and MUC5B within the overall airway mucus while providing information on their spatial distribution.
Sat Jan 01 00:00:00 EST 2022
Airway surface hyperviscosity and defective mucociliary transport by IL-17/TNF-α are corrected by β-adrenergic stimulus.
JCI insight
Guidone D,Buccirossi M,Scudieri P,Genovese M,Sarnataro S,De Cegli R,Cresta F,Terlizzi V,Planelles G,Crambert G,Sermet I,Galietta LJ
MA5-12178 was used in Immunocytochemistry-immunofluorescence to investigate the effects of IL-17A and TNF-α, two cytokines with a relevant role in CF and other chronic lung diseases.
Tue Nov 22 00:00:00 EST 2022
Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.
Current protocols
Ngan SY,Quach HT,Laselva O,Huang EN,Mangos M,Xia S,Bear CE,Wong AP
MA5-12178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin) to optimize previously published protocols to efficiently generate three developmental stages of the lung model (fetal lung epithelial progenitors, fLEP; immature airway epithelial spheroid, AES; air-liquid interface culture, ALI), and demonstrate its potential for cystic fibrosis (CF) drug discovery platforms.
Sat Jan 01 00:00:00 EST 2022
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.
Cell stem cell
Hawkins FJ,Suzuki S,Beermann ML,Barillà C,Wang R,Villacorta-Martin C,Berical A,Jean JC,Le Suer J,Matte T,Simone-Roach C,Tang Y,Schlaeger TM,Crane AM,Matthias N,Huang SXL,Randell SH,Wu J,Spence JR,Carraro G,Stripp BR,Rab A,Sorsher EJ,Horani A,Brody SL,Davis BR,Kotton DN
MA5-12178 was used in Immunohistochemistry to report the directed differentiation of human iPSCs into airway basal cells ("iBCs"), a population resembling the stem cell of the airway epithelium.
Thu Jan 07 00:00:00 EST 2021
An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells.
The EMBO journal
Lamers MM,van der Vaart J,Knoops K,Riesebosch S,Breugem TI,Mykytyn AZ,Beumer J,Schipper D,Bezstarosti K,Koopman CD,Groen N,Ravelli RBG,Duimel HQ,Demmers JAA,Verjans GMGM,Koopmans MPG,Muraro MJ,Peters PJ,Clevers H,Haagmans BL
MA5-12178 was used in Immunocytochemistry-immunoflourescence to represent an experimental model for SARS-CoV-2 infection and can be applied for drug screens.
Mon Mar 01 00:00:00 EST 2021
Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells.
American journal of respiratory cell and molecular biology
Bodas M,Moore AR,Subramaniyan B,Georgescu C,Wren JD,Freeman WM,Brown BR,Metcalf JP,Walters MS
MA5-12178 was used in Immunocytochemistry to identify NOTCH3 activation as one of the important mechanisms by which cigarette smoke induces goblet cell differentiation, thus providing a novel potential strategy to control GCMH-related pathologies in smokers and patients with COPD.
Thu Apr 01 00:00:00 EDT 2021
Mucus Hypersecretion and Ciliary Impairment in Conducting Airway Contribute to Alveolar Mucus Plugging in Idiopathic Pulmonary Fibrosis.
Frontiers in cell and developmental biology
Peng Y,Wang ZN,Xu AR,Fang ZF,Chen SY,Hou XT,Zhou ZQ,Lin HM,Xie JX,Tang XX,Wang DY,Zhong NS
MA5-12178 was used in Immunohistochemistry to investigate whether the muco-ciliary clearance abnormalities in conducting airway are involved in idiopathic pulmonary fibrosis pathogenesis.
Sat Feb 19 00:00:00 EST 2022
Differential responses to e-cig generated aerosols from humectants and different forms of nicotine in epithelial cells from nonsmokers and smokers.
American journal of physiology. Lung cellular and molecular physiology
Escobar YH,Morrison CB,Chen Y,Hickman E,Love CA,Rebuli ME,Surratt JD,Ehre C,Jaspers I
MA5-12178 was used in Western Blotting to indicate that the e-cig generated aerosols from the humectants, mostly GLY, and the type of nicotine used, cause differential effects in airway epithelial cells from nonsmokers and smokers.
Tue Jun 01 00:00:00 EDT 2021
In well-differentiated primary human bronchial epithelial cells, TGF-β1 and TGF-β2 induce expression of furin.
American journal of physiology. Lung cellular and molecular physiology
O'Sullivan MJ,Mitchel JA,Mwase C,McGill M,Kanki P,Park JA
MA5-12178 was used in Immunocytochemistry to look into whether well-differentiated HBE cells maintained in air-liquid interface is a reliable in vitro system for investigating cellular mechanisms of SARS-CoV-2 infection.
Mon Feb 01 00:00:00 EST 2021
Overexpression of Substance P in pig airways increases MUC5AC through an NF-kβ pathway.
Physiological reports
Sponchiado M,Liao YS,Atanasova KR,Collins EN,Schurmann V,Bravo L,Reznikov LR
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Mon Feb 01 00:00:00 EST 2021
Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells.
STAR protocols
Manna V,Caradonna S
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry (Paraffin)
Fri Dec 17 00:00:00 EST 2021
Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells.
STAR protocols
Manna V,Caradonna S
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry (Paraffin)
Fri Dec 17 00:00:00 EST 2021
Extracellular Vesicles Secreted by Mesenchymal Stromal Cells Exert Opposite Effects to Their Cells of Origin in Murine Sodium Dextran Sulfate-Induced Colitis.
Frontiers in immunology
Tolomeo AM,Castagliuolo I,Piccoli M,Grassi M,Magarotto F,De Lazzari G,Malvicini R,Caicci F,Franzin C,Scarpa M,Macchi V,De Caro R,Angriman I,Viola A,Porzionato A,Pozzobon M,Muraca M
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Wed Sep 15 00:00:00 EDT 2021
Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke.
Current research in toxicology
Czekala L,Wieczorek R,Simms L,Yu F,Budde J,Trelles Sticken E,Rudd K,Verron T,Brinster O,Stevenson M,Walele T
MA5-12178 was used in Immunohistochemistry to explore the link between the tobacco harm reduction in different recreational smoking techniques and relating chronic respiratory diseases.
Fri Aug 06 00:00:00 EDT 2021
Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke.
Current research in toxicology
Czekala L,Wieczorek R,Simms L,Yu F,Budde J,Trelles Sticken E,Rudd K,Verron T,Brinster O,Stevenson M,Walele T
MA5-12178 was used in Immunohistochemistry to explore the link between the tobacco harm reduction in different recreational smoking techniques and relating chronic respiratory diseases.
Fri Aug 06 00:00:00 EDT 2021
Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.
Scientific reports
Sweeter JM,Kudrna K,Hunt K,Thomes P,Dickey BF,Brody SL,Dickinson JD
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Tue Jun 22 00:00:00 EDT 2021
Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.
Scientific reports
Sweeter JM,Kudrna K,Hunt K,Thomes P,Dickey BF,Brody SL,Dickinson JD
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Tue Jun 22 00:00:00 EDT 2021
Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.
Scientific reports
Sweeter JM,Kudrna K,Hunt K,Thomes P,Dickey BF,Brody SL,Dickinson JD
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Tue Jun 22 00:00:00 EDT 2021
The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation.
Cells
Bodas M,Subramaniyan B,Moore AR,Metcalf JP,Ocañas SR,Freeman WM,Georgescu C,Wren JD,Walters MS
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Thu Nov 18 00:00:00 EST 2021
Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional.
Nature communications
Stancil IT,Michalski JE,Davis-Hall D,Chu HW,Park JA,Magin CM,Yang IV,Smith BJ,Dobrinskikh E,Schwartz DA
MA5-12178 was used in Immunocytochemistry to illustrate the active mechanisms regulating airway epithelial-driven fibrosis and identify targets to modulate disease progression.
Tue Jul 27 00:00:00 EDT 2021
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.
Cell reports
Mulay A,Konda B,Garcia G,Yao C,Beil S,Villalba JM,Koziol C,Sen C,Purkayastha A,Kolls JK,Pociask DA,Pessina P,de Aja JS,Garcia-de-Alba C,Kim CF,Gomperts B,Arumugaswami V,Stripp BR
MA5-12178 was used in Immunohistochemistry to develop primary human lung epithelial infection models to understand initial responses of proximal and distal lung epithelium to SARS-CoV-2 infection.
Tue May 04 00:00:00 EDT 2021
Paediatric gastric organoids as a tool for disease modelling and clinical translation.
Pediatric surgery international
Jones BC,Calà G,De Coppi P,Giobbe GG
MA5-12178 was used in Immunohistochemistry-immunofluorescence to establish a protocol for deriving gastric epithelial organoids from paediatric gastric biopsies, providing a platform for modelling disease and developing translational therapies.
Mon Mar 01 00:00:00 EST 2021
Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs.
American journal of respiratory and critical care medicine
Carraro G,Mulay A,Yao C,Mizuno T,Konda B,Petrov M,Lafkas D,Arron JR,Hogaboam CM,Chen P,Jiang D,Noble PW,Randell SH,McQualter JL,Stripp BR
MA5-12178 was used in Immunohistochemistry to decipher the transcriptome of freshly isolated epithelial cells from normal and IPF lungs to discern disease-dependent changes within basal stem cells.
Tue Dec 01 00:00:00 EST 2020
Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.
Cell stem cell
Purkayastha A,Sen C,Garcia G,Langerman J,Shia DW,Meneses LK,Vijayaraj P,Durra A,Koloff CR,Freund DR,Chi J,Rickabaugh TM,Mulay A,Konda B,Sim MS,Stripp BR,Plath K,Arumugaswami V,Gomperts BN
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Thu Dec 03 00:00:00 EST 2020
Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.
Cell stem cell
Purkayastha A,Sen C,Garcia G,Langerman J,Shia DW,Meneses LK,Vijayaraj P,Durra A,Koloff CR,Freund DR,Chi J,Rickabaugh TM,Mulay A,Konda B,Sim MS,Stripp BR,Plath K,Arumugaswami V,Gomperts BN
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Thu Dec 03 00:00:00 EST 2020
Vagal sensory neurons drive mucous cell metaplasia.
The Journal of allergy and clinical immunology
Talbot S,Doyle B,Huang J,Wang JC,Ahmadi M,Roberson DP,Yekkirala A,Foster SL,Browne LE,Bean BP,Levy BD,Woolf CJ
MA5-12178 was used in Immunohistochemistry-immunofluorescence to investigate the role of vagal sensory neurones in mucous production using optogenetics.
Mon Jun 01 00:00:00 EDT 2020
Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.
Development (Cambridge, England)
Sayols S,Klassek J,Werner C,Möckel S,Ritz S,Mendez-Lago M,Soshnikova N
MA5-12178 was used in Immunohistochemistry to assess whether Axin2- and Lgr5-expressing cells are gastric progenitors in the developing mouse stomach.
Tue Sep 15 00:00:00 EDT 2020
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.
American journal of physiology. Lung cellular and molecular physiology
Liao YSJ,Kuan SP,Guevara MV,Collins EN,Atanasova KR,Dadural JS,Vogt K,Schurmann V,Bravo L,Eken E,Sponchiado M,Reznikov LR
MA5-12178 was used in Immunohistochemistry-immunofluorescence to study the effect of early life transient airway acidification on mucus secretion and transport properties.
Fri May 01 00:00:00 EDT 2020
Investigation on Ciliary Functionality of Different Airway Epithelial Cell Lines in Three-Dimensional Cell Culture.
Tissue engineering. Part A
Lodes N,Seidensticker K,Perniss A,Nietzer S,Oberwinkler H,May T,Walles T,Hebestreit H,Hackenberg S,Steinke M
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Wed Apr 01 00:00:00 EDT 2020
Investigation on Ciliary Functionality of Different Airway Epithelial Cell Lines in Three-Dimensional Cell Culture.
Tissue engineering. Part A
Lodes N,Seidensticker K,Perniss A,Nietzer S,Oberwinkler H,May T,Walles T,Hebestreit H,Hackenberg S,Steinke M
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Wed Apr 01 00:00:00 EDT 2020
Airway cholinergic history modifies mucus secretion properties to subsequent cholinergic challenge in diminished chloride and bicarbonate conditions.
Experimental physiology
Liao YSJ,Collins EN,Guevara MV,Schurmann V,Atanasova KR,Bravo L,Sponchiado M,Hoegger MJ,Reznikov LR
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing.
Cell reports
Greaney AM,Adams TS,Brickman Raredon MS,Gubbins E,Schupp JC,Engler AJ,Ghaedi M,Yuan Y,Kaminski N,Niklason LE
MA5-12178 was used in Immunohistochemistry-immunofluorescence to identify the platform-specific effects that support the use of engineered models to achieve the most physiologic differential outcomes in pulmonary epithelial regenerative applications.
Tue Mar 24 00:00:00 EDT 2020
Pancreatic cancer triggers diabetes through TGF-β-mediated selective depletion of islet β-cells.
Life science alliance
Parajuli P,Nguyen TL,Prunier C,Razzaque MS,Xu K,Atfi A
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Mon Jun 01 00:00:00 EDT 2020
Pancreatic cancer triggers diabetes through TGF-β-mediated selective depletion of islet β-cells.
Life science alliance
Parajuli P,Nguyen TL,Prunier C,Razzaque MS,Xu K,Atfi A
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Mon Jun 01 00:00:00 EDT 2020
Host-Pathogen Responses to Pandemic Influenza H1N1pdm09 in a Human Respiratory Airway Model.
Viruses
Pharo EA,Williams SM,Boyd V,Sundaramoorthy V,Durr PA,Baker ML
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Wed Jun 24 00:00:00 EDT 2020
Host-Pathogen Responses to Pandemic Influenza H1N1pdm09 in a Human Respiratory Airway Model.
Viruses
Pharo EA,Williams SM,Boyd V,Sundaramoorthy V,Durr PA,Baker ML
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Wed Jun 24 00:00:00 EDT 2020
Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis.
Genes
Liu Z,Anderson JD,Deng L,Mackay S,Bailey J,Kersh L,Rowe SM,Guimbellot JS
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Fri May 29 00:00:00 EDT 2020
Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis.
Genes
Liu Z,Anderson JD,Deng L,Mackay S,Bailey J,Kersh L,Rowe SM,Guimbellot JS
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Fri May 29 00:00:00 EDT 2020
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.
bioRxiv : the preprint server for biology
Mulay A,Konda B,Garcia G,Yao C,Beil S,Sen C,Purkayastha A,Kolls JK,Pociask DA,Pessina P,de Aja JS,Garcia-de-Alba C,Kim CF,Gomperts B,Arumugaswami V,Stripp BR
MA5-12178 was used in Immunocytochemistry to provide a relevant platform for studying COVID-19 pathobiology and for rapid drug screening against SARS-CoV-2 and future emergent respiratory pathogens.
Mon Jun 29 00:00:00 EDT 2020
Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.
Cell stem cell
Han S,Fink J,Jörg DJ,Lee E,Yum MK,Chatzeli L,Merker SR,Josserand M,Trendafilova T,Andersson-Rolf A,Dabrowska C,Kim H,Naumann R,Lee JH,Sasaki N,Mort RL,Basak O,Clevers H,Stange DE,Philpott A,Kim JK,Simons BD,Koo BK
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunofluorescence
Thu Sep 05 00:00:00 EDT 2019
Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.
Cell stem cell
Han S,Fink J,Jörg DJ,Lee E,Yum MK,Chatzeli L,Merker SR,Josserand M,Trendafilova T,Andersson-Rolf A,Dabrowska C,Kim H,Naumann R,Lee JH,Sasaki N,Mort RL,Basak O,Clevers H,Stange DE,Philpott A,Kim JK,Simons BD,Koo BK
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunofluorescence
Thu Sep 05 00:00:00 EDT 2019
A New Ophthalmic Pharmaceutical Formulation, Topical Sulglycotide, Enhances the Ocular Mucin Secretion in Desiccation Stress-Mediated Dry Eye Disease.
Investigative ophthalmology & visual science
Lee H,Jeon S,Kim CE,Park YJ,Yang J
MA5-12178 was used in Immunohistochemistry-immunofluorescence to suggest that topical sulglycotide enhances the ocular mucin secretion in dry eye disease and can be used as a new ophthalmic pharmaceutical material to treat dry eye disease.
Fri Mar 01 00:00:00 EST 2019
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Cellular and molecular gastroenterology and hepatology
Wang Y,Kim R,Sims CE,Allbritton NL
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunocytochemistry
Mon Jul 20 00:00:00 EDT 2020
Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia.
Nature communications
Krishnamurthy S,Wohlford-Lenane C,Kandimalla S,Sartre G,Meyerholz DK,Théberge V,Hallée S,Duperré AM,Del'Guidice T,Lepetit-Stoffaes JP,Barbeau X,Guay D,McCray PB
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunofluorescence
Mon Oct 28 00:00:00 EDT 2019
Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia.
Nature communications
Krishnamurthy S,Wohlford-Lenane C,Kandimalla S,Sartre G,Meyerholz DK,Théberge V,Hallée S,Duperré AM,Del'Guidice T,Lepetit-Stoffaes JP,Barbeau X,Guay D,McCray PB
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunofluorescence
Mon Oct 28 00:00:00 EDT 2019
IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis via STAT3 Pathway.
Frontiers in immunology
Lai X,Li X,Chang L,Chen X,Huang Z,Bao H,Huang J,Yang L,Wu X,Wang Z,Bellanti JA,Zheng SG,Zhang G
MA5-12178 was used in Immunohistochemistry to propose that IL-19 up-regulates MUC5AC-induced mucin production via the STAT3 pathway in CRS, highlighting the important role IL-19 may play in mucin production in chronic respiratory diseases.
Mon Sep 28 00:00:00 EDT 2020
Annexin A2 Expression in Aerogenous Metastasis of Pulmonary Invasive Mucinous Adenocarcinoma: A Case Report including Immunohistochemical Analysis.
Case reports in oncological medicine
Arai K,Hirose M
MA5-12178 was used in Immunohistochemistry to indicate that ANX A2 near the tumor cell surface was related to alveolar wall attachment.
Thu Oct 01 00:00:00 EDT 2020
Influenza A virus surface proteins are organized to help penetrate host mucus.
eLife
Vahey MD,Fletcher DA
MA5-12178 was used in Immunocytochemistry to show that asymmetric distributions of influenza A virus surface proteins help to promote penetration across host mucosal barriers.
Tue May 14 00:00:00 EDT 2019
Increased expression of ATP12A proton pump in cystic fibrosis airways.
JCI insight
Scudieri P,Musante I,Caci E,Venturini A,Morelli P,Walter C,Tosi D,Palleschi A,Martin-Vasallo P,Sermet-Gaudelus I,Planelles G,Crambert G,Galietta LJ
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Thu Oct 18 00:00:00 EDT 2018
Increased expression of ATP12A proton pump in cystic fibrosis airways.
JCI insight
Scudieri P,Musante I,Caci E,Venturini A,Morelli P,Walter C,Tosi D,Palleschi A,Martin-Vasallo P,Sermet-Gaudelus I,Planelles G,Crambert G,Galietta LJ
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Thu Oct 18 00:00:00 EDT 2018
Expansion of Airway Basal Cells and Generation of Polarized Epithelium.
Bio-protocol
Levardon H,Yonker LM,Hurley BP,Mou H
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunofluorescence
Tue Jun 05 00:00:00 EDT 2018
An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy.
Molecular therapy. Methods & clinical development
Duncan GA,Kim N,Colon-Cortes Y,Rodriguez J,Mazur M,Birket SE,Rowe SM,West NE,Livraghi-Butrico A,Boucher RC,Hanes J,Aslanidi G,Suk JS
MA5-12178 was used in Immunocytochemistry-immunoflourescence to motivate further evaluation and clinical development of AAV6 for inhaled gene therapy.
Fri Jun 15 00:00:00 EDT 2018
Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway.
PLoS biology
Weeden CE,Chen Y,Ma SB,Hu Y,Ramm G,Sutherland KD,Smyth GK,Asselin-Labat ML
MA512178 was used in flow cytometry to determine that human basal stem cells isolated from heavy smokers proliferate extensively, whereas their alveolar progenitor cell counterparts have limited colony-forming capacity
Sun Jan 01 00:00:00 EST 2017
Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation.
American journal of physiology. Lung cellular and molecular physiology
Aguilera-Aguirre L,Hao W,Pan L,Li X,Saavedra-Molina A,Bacsi A,Radak Z,Sur S,Brasier AR,Ba X,Boldogh I
MA5-12178 was used in an ELISA assay to demonstrate the roles of OGG1 signaling in the regulation of antigen-driven allergic immune responses via differential expression of miRNAs upstream of Th2 cytokines and eosinophils.
Fri Dec 01 00:00:00 EST 2017
Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Liu SC,Lin CS,Chen SG,Chu YH,Lee FP,Lu HH,Wang HW
MA512178 was used in western blot to investigate the effects of glucocorticoids and H1-antihistamine treatment on human nasal epithelial cells
Wed Feb 01 00:00:00 EST 2017
The identification of the TRPM8 channel on primary culture of human nasal epithelial cells and its response to cooling.
Medicine
Liu SC,Lu HH,Fan HC,Wang HW,Chen HK,Lee FP,Yu CJ,Chu YH
MA5-12178 was used in Western Blot to demonstrate that TRPM8 is present in the nasal epithelium and its channels are important regulators of mucin production.
Tue Aug 01 00:00:00 EDT 2017
RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.
The Journal of clinical investigation
Lesina M,Wörmann SM,Morton J,Diakopoulos KN,Korneeva O,Wimmer M,Einwächter H,Sperveslage J,Demir IE,Kehl T,Saur D,Sipos B,Heikenwälder M,Steiner JM,Wang TC,Sansom OJ,Schmid RM,Algül H
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Mon Aug 01 00:00:00 EDT 2016
Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect.
PLoS biology
Veit G,Oliver K,Apaja PM,Perdomo D,Bidaud-Meynard A,Lin ST,Guo J,Icyuz M,Sorscher EJ,Hartman JL,Lukacs GL
MA5-12178 was used in immunocytochemistry to study the partial correction of the delta-F508-CFTR functional expression defect by ribosomal stalk protein silencing
Sun May 01 00:00:00 EDT 2016
Gastric Proteins MUC5AC and TFF1 as Potential Diagnostic Markers of Colonic Sessile Serrated Adenomas/Polyps.
American journal of clinical pathology
Khaidakov M,Lai KK,Roudachevski D,Sargsyan J,Goyne HE,Pai RK,Lamps LW,Hagedorn CH
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunofluorescence
Tue Nov 01 00:00:00 EDT 2016
Generation of airway epithelial cells with native characteristics from mouse induced pluripotent stem cells.
Cell and tissue research
Yoshie S,Imaizumi M,Nakamura R,Otsuki K,Ikeda M,Nomoto Y,Wada I,Omori K
MA512178 was used in immunocytochemistry to characterize airway epithelial cells derived from induced pluripotent stem cells
Sun May 01 00:00:00 EDT 2016
Complex APC germline mutation associated metaplasia and intraepithelial neoplasia (CAM-IEN) of the gallbladder.
Pathology, research and practice
Böger C,Haag J,Egberts JH,Röcken C
MA5-12178 was used in immunohistochemistry - paraffin section to report a unique case of familial adenomatous polyposis
Fri Jan 01 00:00:00 EST 2016
Production of 3-D Airway Organoids From Primary Human Airway Basal Cells and Their Use in High-Throughput Screening.
Current protocols in stem cell biology
Hild M,Jaffe AB
MA512178 was used in immunocytochemistry to describe the culture of organoids derived from primary human airway basal cells.
Thu May 12 00:00:00 EDT 2016
Suppressive effects of coixol, glyceryl trilinoleate and natural products derived from Coix Lachryma-Jobi var. ma-yuen on gene expression, production and secretion of airway MUC5AC mucin.
Archives of pharmacal research
Lee HJ,Ryu J,Park SH,Seo EK,Han AR,Lee SK,Kim YS,Hong JH,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study the inhibition of airway epitheilal cell MUC5AC expression and secretion by natural products extracted from Coix Lachryma-Jobi var. ma-yuen
Fri Feb 12 00:00:00 EST 2016
Club cell 10-kDa protein attenuates airway mucus hypersecretion and inflammation.
The European respiratory journal
Tokita E,Tanabe T,Asano K,Suzaki H,Rubin BK
MA5-12178 was used in ELISA to study the mechanism by which club cell 10-kDa protein reduces MUC5AC secretion and inflammatory responses of LPS-stimulated human brocnchial epithelial cells
Wed Oct 01 00:00:00 EDT 2014
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma.
Nature cell biology
von Figura G,Fukuda A,Roy N,Liku ME,Morris Iv JP,Kim GE,Russ HA,Firpo MA,Mulvihill SJ,Dawson DW,Ferrer J,Mueller WF,Busch A,Hertel KJ,Hebrok M
MA5-12178 was used in immunohistochemistry to study the formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma and the suppressive role of the Brg1 component of chromatin remodeling complexes
Sat Mar 01 00:00:00 EST 2014
Supplementation with γ-tocopherol attenuates endotoxin-induced airway neutrophil and mucous cell responses in rats.
Free radical biology & medicine
Wagner JG,Birmingham NP,Jackson-Humbles D,Jiang Q,Harkema JR,Peden DB
MA5-12178 was used in ELISA to study the ability of dietary gamma-tocopherol to protect against mucus hypersecretion and neutrophil-mediated injury in a rat LPS-stimulated airway model
Sat Mar 01 00:00:00 EST 2014
Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.
Antioxidants & redox signaling
Strengert M,Jennings R,Davanture S,Hayes P,Gabriel G,Knaus UG
MA5-12178 was used in immunocytochemistry to study the role of mucosal ROS generated by Duox NADPH oxidases in anti-viral responses to influenza A infection
Tue Jun 10 00:00:00 EDT 2014
Effects of the root of Platycodon grandiflorum on airway mucin hypersecretion in vivo and platycodin D(3) and deapi-platycodin on production and secretion of airway mucin in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Ryu J,Lee HJ,Park SH,Kim J,Lee D,Lee SK,Kim YS,Hong JH,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study the effects of root extracts on the PMA-stimulated hypersecretion of MUC5AC by airway epithelial cells in vitro and in a rat model of pulmonary hypersecretion
Sat Mar 15 00:00:00 EDT 2014
Effects of ophiopogonin D and spicatoside A derived from Liriope Tuber on secretion and production of mucin from airway epithelial cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Park SH,Lee HJ,Ryu J,Son KH,Kwon SY,Lee SK,Kim YS,Hong JH,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study the effects of ophiopogonin D and spicatoside A on basal and PMA-induced airway epithelial cell mucin production and secretion
Wed Jan 15 00:00:00 EST 2014
Inhibition of TNF-α-induced MUC5AC mucin gene expression and production by wogonin through the inactivation of NF-κB signaling in airway epithelial cells.
Phytotherapy research : PTR
Sikder MA,Lee HJ,Mia MZ,Park SH,Ryu J,Kim JH,Min SY,Hong JH,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study the role of NFkB in the mechanism by which wogonin inhibits TNF-alpha-induced MUC5AC expression by airway epithelial cells
Wed Jan 01 00:00:00 EST 2014
Cigarette smoke alters non-neuronal cholinergic system components inducing MUC5AC production in the H292 cell line.
European journal of pharmacology
Montalbano AM,Albano GD,Anzalone G,Bonanno A,Riccobono L,Di Sano C,Gagliardo R,Siena L,Pieper MP,Gjomarkaj M,Profita M
MA5-12178 was used in flow cytometry to study the role of changes in non-neuronal acetyl choline metabolism in the mechanism by which cigarette smoke induces MUC5AC expression in a human cell line
Tue Aug 05 00:00:00 EDT 2014
Macrolides attenuate phorbol ester-induced tumor necrosis factor-α and mucin production from human airway epithelial cells.
Pharmacology
Poachanukoon O,Koontongkaew S,Monthanapisut P,Pattanacharoenchai N
MA5-12178 was used in ELISA to study the reduced TNF-alpha and mucin production of PMA-stimulated human airway epithelial cells treated with macrolide antibiotics
Thu Nov 06 00:00:00 EST 2014
Apigenin and Wogonin Regulate Epidermal Growth Factor Receptor Signaling Pathway Involved in MUC5AC Mucin Gene Expression and Production from Cultured Airway Epithelial Cells.
Tuberculosis and respiratory diseases
Sikder MA,Lee HJ,Ryu J,Park SH,Kim JO,Hong JH,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study the mechanisms underlying the inhibition of EGF-induced airway epithelial cell MUC5AC expresson and secretion by apigenin and wogonin
Sat Mar 01 00:00:00 EST 2014
Gastric signet ring cell carcinoma presenting as diffuse, infiltrating myositis--a case report and review of the literature.
Journal of gastrointestinal cancer
Futtrup TB,Hasselby JP,Baeksgaard L
MA5-12178 was used in immunohistochemistry to report on a case of gastric signet ring cell carcinoma
Mon Dec 01 00:00:00 EST 2014
Members of the EpCAM signalling pathway are expressed in gastric cancer tissue and are correlated with patient prognosis.
British journal of cancer
Warneke VS,Behrens HM,Haag J,Krüger S,Simon E,Mathiak M,Ebert MP,Röcken C
MA5-12178 was used in immunohistochemistry to study the prognostic value of members of the EpCAM signalling pathway in gastric cancer
Tue Oct 15 00:00:00 EDT 2013
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.
eLife
Mitrovic S,Nogueira C,Cantero-Recasens G,Kiefer K,Fernández-Fernández JM,Popoff JF,Casano L,Bard FA,Gomez R,Valverde MA,Malhotra V
MA5-12178 was used in immunocytochemistry and western blot to study the secretion of MUC5AC by human colon goblet cells and the regulatory role played by the Ca(2+)-activated TRPM5 ion channel
Tue May 28 00:00:00 EDT 2013
Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice.
American journal of physiology. Lung cellular and molecular physiology
Park JA,Sharif AS,Shiomi T,Kobzik L,Kasahara DI,Tschumperlin DJ,Voynow J,Drazen JM
MA5-12178 was used in immunohistochemistry to study the reduced human neutrophil elastase-induced goblet cell metaplasia observed in TACE-deficient mice
Wed May 15 00:00:00 EDT 2013
Protein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs.
American journal of physiology. Lung cellular and molecular physiology
Bartlett JA,Albertolle ME,Wohlford-Lenane C,Pezzulo AA,Zabner J,Niles RK,Fisher SJ,McCray PB,Williams KE
MA5-12178 was used in western blot to develop methods to study the proteome of the fluid lining the porcine lung
Thu Aug 01 00:00:00 EDT 2013
Vesicular nucleotide transporter regulates the nucleotide content in airway epithelial mucin granules.
American journal of physiology. Cell physiology
Sesma JI,Kreda SM,Okada SF,van Heusden C,Moussa L,Jones LC,O'Neal WK,Togawa N,Hiasa M,Moriyama Y,Lazarowski ER
MA5-12178 was used in immunocytochemistry to study the role of the SLC17A9 vesicular nucleotide transporter in modulating nucleotide levels in mucin granules of airway epithelium
Wed May 15 00:00:00 EDT 2013
Blocking of thromboxane A₂ receptor attenuates airway mucus hyperproduction induced by cigarette smoke.
European journal of pharmacology
An J,Li JQ,Wang T,Li XO,Guo LL,Wan C,Liao ZL,Dong JJ,Xu D,Wen FQ
MA5-12178 was used in immunohistochemistry to study the mechanisms underlying the inhibition of cigarette smoke-induced airway mucus hypersecretion by a thromboxane A2 receptor antagonist
Tue Mar 05 00:00:00 EST 2013
Rhythmic pressure waves induce mucin5AC expression via an EGFR-mediated signaling pathway in human airway epithelial cells.
DNA and cell biology
Liu C,Li Q,Zhou X,Kolosov VP,Perelman JM
MA5-12178 was used in ELISA to study the role of EGFR signaling in the mechanism by which rhythmic pressure waves induce the expression of MUC5AC in airway epithelial cells
Thu Aug 01 00:00:00 EDT 2013
Regulator of G-protein signaling 2 inhibits acid-induced mucin5AC hypersecretion in human airway epithelial cells.
Respiratory physiology & neurobiology
Liu C,Li Q,Zhou X,Kolosov VP,Perelman JM
MA5-12178 was used in ELISA to study the ability of RGS2 to inhibit MUC5AC hypersecretion by human airway epithelial cells in response to airway acidification
Tue Jan 15 00:00:00 EST 2013
TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.
Experimental lung research
Harrop CA,Gore RB,Evans CM,Thornton DJ,Herrick SE
MA5-12178 was used in western blot to study the regulation of basal and IL-13-stimulated primary human bronchial epithelial cell mucin production by TGF-beta2
Fri Feb 01 00:00:00 EST 2013
Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma.
PloS one
Mushaben EM,Brandt EB,Hershey GK,Le Cras TD
MA5-12178 was used in immunohistochemistry to study the effects of rapamycin and dexamethasone on various aspects of established allergic asthma in a murine house dust mite model
Fri Jul 19 00:00:00 EDT 2013
Effect of Prunetin on TNF-α-Induced MUC5AC Mucin Gene Expression, Production, Degradation of IκB and Translocation of NF-κB p65 in Human Airway Epithelial Cells.
Tuberculosis and respiratory diseases
Ryu J,Lee HJ,Park SH,Sikder MA,Kim JO,Hong JH,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study TNF-alpha induced MUC5AC expression, IkB degradation and NFkB p65 translocation in airway epithelial cells and the effects of prunectin
Fri Nov 01 00:00:00 EDT 2013
Early Gastric Cancer-Like Advanced Gastric Cancer versus Advanced Gastric Cancer-Like Early Gastric Cancer.
Clinical endoscopy
Park HS,Lee SY,Hong SN,Kim JH,Sung IK,Park HS,Shim CS,Jin CJ
MA5-12178 was used in immunohistochemistry to study endoscopic differences between early gastric cancer that resembles advanced gastric cancer and advanced gastric cancer that resembles early gastric cancer
Fri Mar 01 00:00:00 EST 2013
The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.
PloS one
Seibold MA,Smith RW,Urbanek C,Groshong SD,Cosgrove GP,Brown KK,Schwarz MI,Schwartz DA,Reynolds SD
MA5-12178 was used in immunohistochemistry to study the presence of mucocilary pseudostratified epithelium in honeycomb cysts of individuals with idiopathic pulmonary fibrosis
Fri Sep 20 00:00:00 EDT 2013
HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/α7-nicotinic acetylcholine receptors.
PloS one
Gundavarapu S,Mishra NC,Singh SP,Langley RJ,Saeed AI,Feghali-Bostwick CA,McIntosh JM,Hutt J,Hegde R,Buch S,Sopori ML
MA5-12178 was used in immunohistochemistry to study the roles of CXCR4 and the alpha7-nicotinic acetylcholine receptor in the mechanism by which HIV gp120 induces human bronchial epithelial cell mucin production
Tue Jun 17 00:00:00 EDT 2014
Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo.
The Journal of allergy and clinical immunology
Gundavarapu S,Wilder JA,Mishra NC,Rir-Sima-Ah J,Langley RJ,Singh SP,Saeed AI,Jaramillo RJ,Gott KM,Peña-Philippides JC,Harrod KS,McIntosh JM,Buch S,Sopori ML
MA5-12178 was used in immunohistochemistry to study the role of acetylcholine and nicotinic receptors in mucus cell pathophysiology and airway mucus formation
Sat Sep 01 00:00:00 EDT 2012
Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.
Histopathology
Kang H,An HJ,Song JY,Kim TH,Heo JH,Ahn DH,Kim G
MA5-12178 was used in immunohistochemistry to study the roles of Notch3 and Jagged2 in gastric carcinogenesis
Mon Oct 01 00:00:00 EDT 2012
Dual oxidase 2 is essential for the toll-like receptor 5-mediated inflammatory response in airway mucosa.
Antioxidants & redox signaling
Joo JH,Ryu JH,Kim CH,Kim HJ,Suh MS,Kim JO,Chung SY,Lee SN,Kim HM,Bae YS,Yoon JH
MA5-12178 was used in immunohistochemistry to investigate the role of DUOX2 in inflammation mediated by TLR5 in airway mucosa
Sun Jan 01 00:00:00 EST 2012
Silibinin regulates gene expression, production and secretion of mucin from cultured airway epithelial cells.
Phytotherapy research : PTR
Kim KD,Lee HJ,Lim SP,Sikder A,Lee SY,Lee CJ
MA5-12178 was used in ELISA to investigate the effect of silibinin on gene expression, production, and secretion of mucin from NCI-H292 cells
Sat Sep 01 00:00:00 EDT 2012
Phorbol ester or epidermal growth-factor-induced MUC5AC mucin gene expression and production from airway epithelial cells are inhibited by apigenin and wogonin.
Phytotherapy research : PTR
Kim JO,Sikder MA,Lee HJ,Rahman M,Kim JH,Chang GT,Lee CJ
MA5-12178 was used in ELISA to study the ability of apigenin and wogonin to inhibit airway epithelial MUC5AC production and secretion
Sat Dec 01 00:00:00 EST 2012
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
The American journal of pathology
Syu LJ,El-Zaatari M,Eaton KA,Liu Z,Tetarbe M,Keeley TM,Pero J,Ferris J,Wilbert D,Kaatz A,Zheng X,Qiao X,Grachtchouk M,Gumucio DL,Merchant JL,Samuelson LC,Dlugosz AA
MA5-12178 was used in immunohistochemistry to study the induction of inflammation, metaplasia and displasia following transgenic expression of IFN-gamma in the murine stomach
Sat Dec 01 00:00:00 EST 2012
Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway.
The American journal of pathology
Vincent DF,Gout J,Chuvin N,Arfi V,Pommier RM,Bertolino P,Jonckheere N,Ripoche D,Kaniewski B,Martel S,Langlois JB,Goddard-Léon S,Colombe A,Janier M,Van Seuningen I,Losson R,Valcourt U,Treilleux I,Dubus P,Bardeesy N,Bartholin L
MA5-12178 was used in immunohistochemistry to study the mechanism of suppression of murine pancreatic tumor transformation by Tif1gamma
Fri Jun 01 00:00:00 EDT 2012
Quercetin attenuates airway inflammation and mucus production induced by cigarette smoke in rats.
International immunopharmacology
Yang T,Luo F,Shen Y,An J,Li X,Liu X,Ying B,Liao Z,Dong J,Guo L,Wang T,Xu D,Chen L,Wen F
MA5-12178 was used in immunohistochemistry and western blot to study the mechanisms by which quercetin protects against cigarette smoke-induced airway inflammation and mucin hypersecretion
Tue May 01 00:00:00 EDT 2012
The inhibition of aldose reductase on mucus production induced by interleukin-13 in the human bronchial epithelial cells.
International immunopharmacology
Jiang D,Li Q,Kolosov VP,Zhou X
MA5-12178 was used in ELISA to study the effect of aldose reductase inhibition or knockdown on IL-13-induced MUC5AC production by human bronchial epithelial cells
Sun Apr 01 00:00:00 EDT 2012
Development of primary human nasal epithelial cell cultures for the study of cystic fibrosis pathophysiology.
American journal of physiology. Cell physiology
de Courcey F,Zholos AV,Atherton-Watson H,Williams MT,Canning P,Danahay HL,Elborn JS,Ennis M
MA5-12178 was used in immunocytochemistry to develop a cell culture system using nasal epithelial cells fron cystic fibrosis patients suitable for studying the pathophysiology of the disease
Sat Dec 01 00:00:00 EST 2012
β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.
Journal of cell science
Hashimoto S,Chen H,Que J,Brockway BL,Drake JA,Snyder JC,Randell SH,Stripp BR
MA5-12178 was used in immunohistochemistry to study the regulation of cell fate in developing airway epithelium by Wnt - beta-catenin signaling
Wed Feb 15 00:00:00 EST 2012
Asian sand dust enhances allergen-induced th2 allergic inflammatory changes and mucin production in BALB/c mouse lungs.
Allergy, asthma & immunology research
Kang IG,Jung JH,Kim ST
MA5-12178 was used in immunohistochemistry to study the effects of Asian sand dust on allergen-induced inflammation and mucin production in BALB/c mouse lungs
Sun Jul 01 00:00:00 EDT 2012
Regulation of particulate matter-induced mucin secretion by transient receptor potential vanilloid 1 receptors.
Inflammation
Yu H,Li Q,Kolosov VP,Perelman JM,Zhou X
MA5-12178 was used in ELISA to study the role of the TRPV1 receptor in human bronchial epithelial MUC5AC secretion in response to particulate matter
Sat Dec 01 00:00:00 EST 2012
Atherogenic and pulmonary responses of ApoE- and LDL receptor-deficient mice to sidestream cigarette smoke.
Toxicology
Han SG,Howatt DA,Daugherty A,Gairola CG
MA5-12178 was used in western blot to study the effects of sidestream smoke on the lung and cardivascular responses of ApoE- and LDL receptor-deficient mice
Fri Sep 28 00:00:00 EDT 2012
Flagellin/TLR5 responses induce mucus hypersecretion by activating EGFR via an epithelial cell signaling cascades.
Experimental cell research
Yu H,Zhou X,Wen S,Xiao Q
MA5-12178 was used in ELISA and immunocytochemistry to study the mechanisms by which Pseudomonas aeruginosa flagellin induces MUC5AC hypersecretion by human airway epithelial cells
Sun Apr 01 00:00:00 EDT 2012
Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo.
Experimental eye research
Fostad IG,Eidet JR,Shatos MA,Utheim TP,Utheim OA,Raeder S,Dartt DA
MA5-12178 was used in immunohistochemistry to study the effect on the ex vivo conjunctival epithelial phenotype of the site of conjunctival harvest and distance from the explant
Thu Nov 01 00:00:00 EDT 2012
Change of mucosal color in early gastric cancer.
Journal of digestive diseases
Lee HH,Lee SY,Yoon HY,Hong SN,Kim JH,Sung IK,Park HS,Shim CS,Han HS
MA5-12178 was used in immunohistochemistry to report on the diagnostic value of mucosal color changes in early gastric cancer
Mon Oct 01 00:00:00 EDT 2012
Effects of an oral MMP-9 and -12 inhibitor, AZD1236, on biomarkers in moderate/severe COPD: a randomised controlled trial.
Pulmonary pharmacology & therapeutics
Dahl R,Titlestad I,Lindqvist A,Wielders P,Wray H,Wang M,Samuelsson V,Mo J,Holt A
MA5-12178 was used in ELISA to study the effects of a selective MMP9 and MMP12 inhibitor on biomarkers of inflammmation and degradation in a Phase IIa clinical trial of moderate-severe COPD
Sun Apr 01 00:00:00 EDT 2012
Regional conjunctivectomy with postoperative mitomycin C to treat chronic hyperemic conjunctiva.
Cornea
Kim BH
MA5-12178 was used in immunohistochemistry to develop a new surgical procedure for the treatment of chronic irreversible hyperemic conjunctiva
Thu Mar 01 00:00:00 EST 2012
Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: implication in mucin over-expression.
Innate immunity
Wu Q,Jiang D,Chu HW
MA5-12178 was used in immunocytochemistry to investigate the effect of cigarette smoke on GDF15 expression in human lung epithelial cells
Wed Aug 01 00:00:00 EDT 2012
Chronic mechanical stress induces mucin 5AC expression in human bronchial epithelial cells through ERK dependent pathways.
Molecular biology reports
Li N,Li Q,Zhou XD,Kolosov VP,Perelman JM
MA5-12178 was used in ELISA to study the role of ERK signaling in the induction of MUC5AC in human bronchial epithelial cells by chronic mechanical stress
Wed Feb 01 00:00:00 EST 2012
Expression of MUC5AC and Trefoil Peptide 1 (TFF1) in the Subtypes of Intestinal Metaplasia.
Clinical endoscopy
Song JY,Kim BW,Lee AW,Lee KY,Chung IS,Lee BI,Choi H,Ji JS,Chae HS,Choi KY
MA5-12178 was used in immunohistochemistry to study the expression of MUC5AC and trefoil peptide-1 in different intestinal neoplastic subtypes obtained at endoscopic biopsy
Fri Jun 01 00:00:00 EDT 2012
Divergent effects of urban particulate air pollution on allergic airway responses in experimental asthma: a comparison of field exposure studies.
Environmental health : a global access science source
Wagner JG,Morishita M,Keeler GJ,Harkema JR
MA5-12178 was used in ELISA to study the effects of different urban particulate sources on airway responses in a rat model of allergic asthma
Fri Jul 06 00:00:00 EDT 2012
Increased human Ca²⁺-activated Cl⁻ channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients.
Respiratory research
Iwashita H,Fujimoto K,Morita S,Nakanishi A,Kubo K
MA5-12178 was used in immunohistochemistry to study the association of increased CLCA1 expression with mucus overproduction in airway epithelia of smokers and COPD patients
Mon Jun 25 00:00:00 EDT 2012
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells.
Respiratory research
Seagrave J,Albrecht HH,Hill DB,Rogers DF,Solomon G
MA5-12178 was used in ELISA to study the effects of guaifenesin, N-acetylcystein and ambroxol on IL-13-stimulated MUC5A expression and rates of muciciliary transport in cultured human airway epithelial cells
Wed Oct 31 00:00:00 EDT 2012
Mucin deficiency causes functional and structural changes of the ocular surface.
PloS one
Floyd AM,Zhou X,Evans C,Rompala OJ,Zhu L,Wang M,Chen Y
MA5-12178 was used in immunohistochemistry to study the effect of MUC5AC deficiency on the ocular surface in knockout mice
Wed Jun 26 00:00:00 EDT 2013
Effect of Chrysin on Gene Expression and Production of MUC5AC Mucin from Cultured Airway Epithelial Cells.
Tuberculosis and respiratory diseases
Shin HD,Lee HJ,Sikder MA,Park SH,Ryu J,Hong JH,Kim JO,Seok JH,Lee CJ
MA5-12178 was used in ELISA to study the effect of chrysin on cultured airway epithelial cell gene expression and MUC5AC mucin production in response to phorbol ester or EGF stimulation
Mon Oct 01 00:00:00 EDT 2012
Triiodothyronine represses MUC5AC expression by antagonizing Sp1 binding to its promoter in human bronchial epithelial HBE16 cells.
Journal of biomedicine & biotechnology
Wang X,Li Q,Zhou X,Kolosov VP,Perelman JM
MA5-12178 was used in ELISA to study the mechanism underlying the repression of MUC5AC expression by triiodothyronine in human bronchial epithelial cells
Fri Sep 07 00:00:00 EDT 2012
Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway.
The Journal of biological chemistry
Lee J,Komatsu K,Lee BC,Lim JH,Jono H,Xu H,Kai H,Zhang ZJ,Yan C,Li JD
MA5-12178 was used in immunohistochemistry to study the role of PDE4B in the upregulation of MUC5AC mucin expression by Streptococcus pneumoniae
Fri Jun 29 00:00:00 EDT 2012
RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism.
American journal of respiratory and critical care medicine
Ma B,Dela Cruz CS,Hartl D,Kang MJ,Takyar S,Homer RJ,Lee CG,Elias JA
MA5-12178 was used in western blot to study the role of type 1 interferons in the inhibition of VEGF tissue responses by RIG-like helicase innate immunity
Sun May 15 00:00:00 EDT 2011
Notch-dependent differentiation of adult airway basal stem cells.
Cell stem cell
Rock JR,Gao X,Xue Y,Randell SH,Kong YY,Hogan BL
MA5-12178 was used in immunohistochemistry to investigate the mechanism underlying airway homeostasis and repair after epithelial damage
Fri Jun 03 00:00:00 EDT 2011
Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice.
Journal of virology
Yageta Y,Ishii Y,Morishima Y,Masuko H,Ano S,Yamadori T,Itoh K,Takeuchi K,Yamamoto M,Hizawa N
MA5-12178 was used in ELISA to investigate the protective effect of Nrf2 on pulmonary inflammation induced by influenza virus in mice exposed to cigarette smoke
Sun May 01 00:00:00 EDT 2011
Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells.
Journal of immunology (Baltimore, Md. : 1950)
Oguma T,Asano K,Tomomatsu K,Kodama M,Fukunaga K,Shiomi T,Ohmori N,Ueda S,Takihara T,Shiraishi Y,Sayama K,Kagawa S,Natori Y,Lilly CM,Satoh K,Makimura K,Ishizaka A
MA5-12178 was used in ELISA to study the mechanism of Aspertillus fumigatus-induced allergic bronchopulmonary mycosis
Fri Jul 15 00:00:00 EDT 2011
Effects of furosemide on allergic asthmatic responses in mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Wang S,Xiang YY,Ellis R,Wattie J,Feng M,Inman MD,Lu WY
MA5-12178 was used in immunohistochemistry to study Na(+)-K(+)-Cl(-) cotransporter expression and the effects of inhibition by furosemide in a murine model of allergic asthma
Sat Oct 01 00:00:00 EDT 2011
Role of aquaporin 5 in antigen-induced airway inflammation and mucous hyperproduction in mice.
Journal of cellular and molecular medicine
Shen Y,Wang Y,Chen Z,Wang D,Wang X,Jin M,Bai C
MA5-12178 was used in immunohistochemistry to study the involvement of the aquaporin 5 water channel in chronic allergic asthma
Wed Jun 01 00:00:00 EDT 2011
Regulation of cigarette smoke-induced mucin expression by neuregulin1β/ErbB3 signalling in human airway epithelial cells.
Basic & clinical pharmacology & toxicology
Yu H,Li Q,Kolosov VP,Perelman JM,Zhou X
MA5-12178 was used in ELISA to determine the role of neuregulin-1 signalling in cigarette smoke-induced expression of mucin in human airway epithelial cells.
Fri Jul 01 00:00:00 EDT 2011
Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells.
Experimental lung research
Seagrave J,Albrecht H,Park YS,Rubin B,Solomon G,Kim KC
MA5-12178 was used in ELISA to study the effect of guaifenesin on mucin production in human airway epithelial cells
Thu Dec 01 00:00:00 EST 2011
Mucin from rheumatoid arthritis synovial fluid enhances interleukin-6 production by human peripheral blood mononuclear cells.
Human immunology
Hamaguchi M,Kawahito Y,Ishino H,Takeuchi N,Tokunaga D,Hojo T,Yamamoto A,Kadoya M,Seno T,Kohno M,Nakada H
MA5-12178 was used in western blot to investigate the involvement of mucins in immunoinflammatory reactions in the pathogenesis of rheumatoid arthritis
Tue Mar 01 00:00:00 EST 2011
Combined tubular adenocarcinoma and hepatoid adenocarcinoma arising in Barrett esophagus.
Annals of diagnostic pathology
Kuroda N,Onishi K,Lee GH
MA5-12178 was used in immunohistochemistry to report on a case of combined tubular adenocarcinoma and hepatoid adenocarcinoma
Thu Dec 01 00:00:00 EST 2011
Simvastatin attenuates acrolein-induced mucin production in rats: involvement of the Ras/extracellular signal-regulated kinase pathway.
International immunopharmacology
Chen YJ,Chen P,Wang HX,Wang T,Chen L,Wang X,Sun BB,Liu DS,Xu D,An J,Wen FQ
MA5-12178 was used in immunohistochemistry to study the mechanism by which Simvastatin inhibits acrolein-induced mucin production
Tue Jun 01 00:00:00 EDT 2010
Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models.
Human pathology
Flatmark K,Davidson B,Kristian A,Stavnes HT,Førsund M,Reed W
MA5-12178 was used in immunohistochemistry to characterize the expression of a number of proteins in tissues from pseudomyxoma peritonei patients
Sun Aug 01 00:00:00 EDT 2010
Primary signet-ring cell carcinoma of the cervix: case report and review of the literature.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Balci S,Saglam A,Usubutun A
MA5-12178 was used in immunohistochemistry to report on a case of primary signet-ring cell carcinoma of the cervix
Mon Mar 01 00:00:00 EST 2010
Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions.
Biochemical and biophysical research communications
Narumoto O,Horiguchi K,Horiguchi S,Moriwaki Y,Takano-Ohmuro H,Shoji S,Misawa H,Yamashita N,Nagase T,Kawashima K,Yamashita N
MA5-12178 was used in immunohistochemistry to study the roles of SLURP-1 in the pathophysiology of asthma.
Fri Aug 06 00:00:00 EDT 2010
Acute pulmonary response of mice to multi-wall carbon nanotubes.
Inhalation toxicology
Han SG,Andrews R,Gairola CG
MA5-12178 was used in western blot to study the effect of exposure to multi-wall carbon nanotubes on the cytokine and cytotoxic responses of mouse lung
Mon Mar 01 00:00:00 EST 2010
Leptin up-regulates MUC5B expression in human airway epithelial cells via mitogen-activated protein kinase pathway.
Experimental lung research
Woo HJ,Yoo WJ,Bae CH,Song SY,Kim YW,Park SY,Kim YD
MA5-12178 was used in ELISA to investigate the mechanism of MUC5B upregulation induced by leptin
Tue Jun 01 00:00:00 EDT 2010
MUC5AC expression in human middle ear epithelium of patients with otitis media.
Archives of otolaryngology--head & neck surgery
Kerschner JE,Tripathi S,Khampang P,Papsin BC
MA5-12178 was used in ELISA to examine the MUC5AC protein level in the middle ear fluids from otitis media patients
Sun Aug 01 00:00:00 EDT 2010
Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.
PLoS genetics
Hata S,Abe M,Suzuki H,Kitamura F,Toyama-Sorimachi N,Abe K,Sakimura K,Sorimachi H
MA5-12178 was used in immunohistochemistry to investigate the role of calpain 8/nCL-2 and calpain 9/nCL-4 in gastric mucosal defense
Thu Jul 29 00:00:00 EDT 2010
Prognostic significance of MUC1, MUC2 and MUC5AC expressions in gastric carcinoma.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
İlhan Ö,Han Ü,Önal B,Çelık SY
MA5-12178 was used in immunohistochemistry to study the prognostic value of MUC1, MUC2 and MUC5AC in gastric carcinoma
Wed Dec 01 00:00:00 EST 2010
Effect of sildenafil on acrolein-induced airway inflammation and mucus production in rats.
The European respiratory journal
Wang T,Liu Y,Chen L,Wang X,Hu XR,Feng YL,Liu DS,Xu D,Duan YP,Lin J,Ou XM,Wen FQ
MA5-12178 was used in immunohistochemistry to study the effect of a PDE5 inhibitor on acrolein-induced airway inflammation and mucus production in rats
Fri May 01 00:00:00 EDT 2009
Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease.
American journal of respiratory and critical care medicine
Cho HY,Imani F,Miller-DeGraff L,Walters D,Melendi GA,Yamamoto M,Polack FP,Kleeberger SR
MA5-12178 was used in western blot to study the protective effects of Nrf2 against respiratory syncytial virus disease
Thu Jan 15 00:00:00 EST 2009
Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma.
The Journal of experimental medicine
Tachdjian R,Mathias C,Al Khatib S,Bryce PJ,Kim HS,Blaeser F,O'Connor BD,Rzymkiewicz D,Chen A,Holtzman MJ,Hershey GK,Garn H,Harb H,Renz H,Oettgen HC,Chatila TA
MA5-12178 was used in immunohistochemistry to study the effects of a disease-associated human IL-4 receptor polymorphism in a mouse model of allergic asthma
Mon Sep 28 00:00:00 EDT 2009
Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury.
British journal of pharmacology
Cortijo J,Iranzo A,Milara X,Mata M,Cerdá-Nicolás M,Ruiz-Saurí A,Tenor H,Hatzelmann A,Morcillo EJ
MA5-12178 was used in ELISA to investigate the effect of roflumilast on lung injury induced by bleomycin
Sun Feb 01 00:00:00 EST 2009
A critical role of SHP-1 in regulation of type 2 inflammation in the lung.
American journal of respiratory cell and molecular biology
Oh SY,Zheng T,Kim YK,Cohn L,Homer RJ,McKenzie AN,Zhu Z
MA5-12178 was used in western blot to study the role of SHP-1 in regulating type 2 inflammation in the lung
Fri May 01 00:00:00 EDT 2009
Regulator of G-protein signaling 4 suppresses LPS-induced MUC5AC overproduction in the airway.
American journal of respiratory cell and molecular biology
Song KS,Kim HJ,Kim K,Lee JG,Yoon JH
MA5-12178 was used in Dot blot to examine the ATP-dependent mechanism by which LPS induces MUC5AC gene expression and identify specific molecules that could suppress LPS-induced MUC5AC expression at a G-protein-coupled receptor level.
Wed Jul 01 00:00:00 EDT 2009
Genistein and curcumin suppress epidermal growth factor-induced MUC5AC mucin production and gene expression from human airway epithelial cells.
Phytotherapy research : PTR
Heo HJ,Lee SY,Lee MN,Lee HJ,Seok JH,Lee CJ
MA5-12178 was used in ELISA to examine the effect of genistein and curcumin on mucin production in human airway epithelial cells
Thu Oct 01 00:00:00 EDT 2009
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice.
American journal of physiology. Lung cellular and molecular physiology
Shinagawa K,Ploplis VA,Castellino FJ
MA5-12178 was used in blocking or activating experiment to investigate the role of coagulation factor VIIa in the asthmatic response in mice
Fri May 01 00:00:00 EDT 2009
Suppression of prostaglandin E2-induced MUC5AC overproduction by RGS4 in the airway.
American journal of physiology. Lung cellular and molecular physiology
Song KS,Choi YH,Kim JM,Lee H,Lee TJ,Yoon JH
MA5-12178 was used in western blot to study the role of RGS4 in suppressing PGE2-induced airway MUC5AC overproduction
Wed Apr 01 00:00:00 EDT 2009
Different effects of telithromycin on MUC5AC production induced by human neutrophil peptide-1 or lipopolysaccharide in NCI-H292 cells compared with azithromycin and clarithromycin.
The Journal of antimicrobial chemotherapy
Ishimoto H,Mukae H,Sakamoto N,Amenomori M,Kitazaki T,Imamura Y,Fujita H,Ishii H,Nakayama S,Yanagihara K,Kohno S
MA5-12178 was used in ELISA to examine the role of human neutrophil peptide-1 in mucus hypersecretion during chronic respiratory tract infections
Thu Jan 01 00:00:00 EST 2009
Mitochondrial dysfunction increases allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Aguilera-Aguirre L,Bacsi A,Saavedra-Molina A,Kurosky A,Sur S,Boldogh I
MA5-12178 was used in ELISA to study the role of dysfunctional mitochondria in allergic airway inflammation
Thu Oct 15 00:00:00 EDT 2009
EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors.
American journal of clinical pathology
Sartori G,Cavazza A,Sgambato A,Marchioni A,Barbieri F,Longo L,Bavieri M,Murer B,Meschiari E,Tamberi S,Cadioli A,Luppi F,Migaldi M,Rossi G
MA5-12178 was used in immunohistochemistry to develop a combined clinicopathologic and molecular scoring system for assessing the tumor responses to EGFR inhibitors
Wed Apr 01 00:00:00 EDT 2009
Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
Journal of cell science
Luxen S,Noack D,Frausto M,Davanture S,Torbett BE,Knaus UG
MA5-12178 was used in immunocytochemistry to investigate the role of Duox NADPH oxidase heterodimerization in its localization in airway cells
Wed Apr 15 00:00:00 EDT 2009
Unclassified mucin phenotype of gastric adenocarcinoma exhibits the highest invasiveness.
Journal of gastroenterology and hepatology
Han HS,Lee SY,Lee KY,Hong SN,Kim JH,Sung IK,Park HS,Jin CJ,Min YI
MA5-12178 was used in immunohistochemistry to investigate phenotypic mucin expression in human gastric adenocarcinoma
Wed Apr 01 00:00:00 EDT 2009
Multipotential ability of primitive germ cells from neonatal pig testis cultured in vitro.
Reproduction, fertility, and development
Goel S,Fujihara M,Tsuchiya K,Takagi Y,Minami N,Yamada M,Imai H
MA5-12178 was used in immunohistochemistry to investigate the stem cell potential of primitive germ cells isolated from neonatal pig testis
Tue Aug 18 00:00:00 EDT 2009
Effects of cigarette smoking on mucin production in human middle ear epithelial cells.
International journal of pediatric otorhinolaryngology
Cho JG,Woo JS,Lee HM,Jung HH,Hwang SJ,Chae S
MA5-12178 was used in western blot to study the effect of cigarette smoking on MUC5AC expression by human middle ear epithelial cells
Thu Oct 01 00:00:00 EDT 2009
Structure of the oesophagus and morphometric, histochemical-immunohistochemical profiles of the oesophageal gland during the post-hatching period of Japanese quails (Coturnix coturnix japonica).
Anatomia, histologia, embryologia
Sağsöz H,Liman N
MA5-12178 was used in immunohistochemistry to investigate the MUC5AC expression in the oesophageal mucosa of quail post-hatching
Thu Oct 01 00:00:00 EDT 2009
Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data.
BMC medical genomics
Tong L,Chew J,Yang H,Ang LP,Tan DT,Beuerman RW
MA5-12178 was used in immunohistochemistry to study the involvement of distinct subsets of genes in the formation and recurrence of pterygia
Tue Mar 10 00:00:00 EDT 2009
Nitric oxide gas phase release in human small airway epithelial cells.
Respiratory research
Jiang J,Malavia N,Suresh V,George SC
MA5-12178 was used in immunocytochemistry to study gaseous NO release in human small airway epithelial cells and the mechanisms underlying its variability
Mon Jan 19 00:00:00 EST 2009
Oligopotent stem cells are distributed throughout the mammalian ocular surface.
Nature
Majo F,Rochat A,Nicolas M,Jaoudé GA,Barrandon Y
MA5-12178 was used in immunohistochemistry to examine the presence of stem cells in mammalian ocular surface
Thu Nov 13 00:00:00 EST 2008
Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.
American journal of respiratory cell and molecular biology
Deshmukh HS,Shaver C,Case LM,Dietsch M,Wesselkamper SC,Hardie WD,Korfhagen TR,Corradi M,Nadel JA,Borchers MT,Leikauf GD
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in ELISA
Tue Apr 01 00:00:00 EDT 2008
Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production.
American journal of respiratory cell and molecular biology
Lee CG,Hartl D,Matsuura H,Dunlop FM,Scotney PD,Fabri LJ,Nash AD,Chen NY,Tang CY,Chen Q,Homer RJ,Baca M,Elias JA
MA5-12178 was used in western blot to examine the role of IL-11 signaling in inflammation and mucus production
Mon Dec 01 00:00:00 EST 2008
CD34+ testicular stromal cells support long-term expansion of embryonic and adult stem and progenitor cells.
Stem cells (Dayton, Ohio)
Kim J,Seandel M,Falciatori I,Wen D,Rafii S
MA5-12178 was used in immunohistochemistry to characterize a CD34+ testicular stromal cell line as a feeder cell line for embryonic and adult stem and progenitor cells
Wed Oct 01 00:00:00 EDT 2008
Heme oxygenase-1 prevents airway mucus hypersecretion induced by cigarette smoke in rodents and humans.
The American journal of pathology
Almolki A,Guenegou A,Golda S,Boyer L,Benallaoua M,Amara N,Bachoual R,Martin C,Rannou F,Lanone S,Dulak J,Burgel PR,El-Benna J,Leynaert B,Aubier M,Boczkowski J
MA5-12178 was used in immunocytochemistry to study the role of heme oxygenase-1 in preventing airway mucus hypersecretion induced by cigarette smoke
Wed Oct 01 00:00:00 EDT 2008
Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro.
The international journal of biochemistry & cell biology
Lin KW,Park J,Crews AL,Li Y,Adler KB
MA5-12178 was used in ELISA to investigate the involvement of PAR-2 in mucin hypersecretion by human bronchial epithelial cells
Wed Aug 13 00:00:00 EDT 2008
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Journal of immunology (Baltimore, Md. : 1950)
Zheng T,Liu W,Oh SY,Zhu Z,Hu B,Homer RJ,Cohn L,Grusby MJ,Elias JA
MA5-12178 was used in western blot to investigate the opposing effect of interleukin 13 and its receptor alpha2 in inflammation
Tue Jan 01 00:00:00 EST 2008
Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950)
Nakao I,Kanaji S,Ohta S,Matsushita H,Arima K,Yuyama N,Yamaya M,Nakayama K,Kubo H,Watanabe M,Sagara H,Sugiyama K,Tanaka H,Toda S,Hayashi H,Inoue H,Hoshino T,Shiraki A,Inoue M,Suzuki K,Aizawa H,Okinami S,Nagai H,Hasegawa M,Fukuda T,Green ED,Izuhara K
MA5-12178 was used in ELISA to examine the role of pendrin in bronchial asthma and chronic obstructive pulmonary disease
Thu May 01 00:00:00 EDT 2008
Role of epidermal growth factor receptor in maintaining airway goblet cell hyperplasia in rats sensitized to allergen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Takeyama K,Tamaoki J,Kondo M,Isono K,Nagai A
MA5-12178 was used in immunocytochemistry to investigate the role of epidermal growth factor receptor in airway goblet cell hyperplasia
Thu May 01 00:00:00 EDT 2008
Munc18/SNARE proteins' regulation of exocytosis in guinea pig duodenal Brunner's gland acini.
World journal of gastroenterology
Cosen-Binker LI,Morris GP,Vanner S,Gaisano HY
MA5-12178 was used in immunohistochemistry to investigate the regulatory effect of Munc18/SNARE proteins on exocytosis in Brunner gland acini
Mon Apr 21 00:00:00 EDT 2008
Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alpha signaling pathways in human airway epithelial cells.
Biochemical and biophysical research communications
Yan F,Li W,Jono H,Li Q,Zhang S,Li JD,Shen H
MA5-12178 was used in immunohistochemistry to investigate the mechanism for upregulation of MUC5AC mucin expression induced by Pseudomonas aeruginosa lipopolysaccharide in human airway epithelial cells
Fri Feb 08 00:00:00 EST 2008
Synergistic induction of MUC5AC mucin by nontypeable Haemophilus influenzae and Streptococcus pneumoniae.
Biochemical and biophysical research communications
Shen H,Yoshida H,Yan F,Li W,Xu F,Huang H,Jono H,Li JD
MA5-12178 was used in ELISA to study the mechanism by which nontypeable Haemophilus influenzae and Streptococcus pneumoniae synergistically induce MUC5AC mucin
Fri Jan 25 00:00:00 EST 2008
Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.
Arthritis and rheumatism
Volin MV,Shahrara S,Haines GK,Woods JM,Koch AE
MA5-12178 was used in immunohistochemistry to study the expression of MUC1, MUC2, MUC3, and MUC5AC in arthritic synovial tissue
Tue Jan 01 00:00:00 EST 2008
MKP1 regulates the induction of MUC5AC mucin by Streptococcus pneumoniae pneumolysin by inhibiting the PAK4-JNK signaling pathway.
The Journal of biological chemistry
Ha UH,Lim JH,Kim HJ,Wu W,Jin S,Xu H,Li JD
MA5-12178 was used in ELISA to study the mechanism by which MUC5AC mucin transcription is induced by Streptococcus pneumoniae pneumolysin
Fri Nov 07 00:00:00 EST 2008
IL-13 induces a bronchial epithelial phenotype that is profibrotic.
Respiratory research
Malavia NK,Mih JD,Raub CB,Dinh BT,George SC
MA5-12178 was used in immunocytochemistry to examine the effect of IL-13 on subepithelial fibrosis
Tue Mar 18 00:00:00 EDT 2008
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma.
Nature medicine
Xiang YY,Wang S,Liu M,Hirota JA,Li J,Ju W,Fan Y,Kelly MM,Ye B,Orser B,O'Byrne PM,Inman MD,Yang X,Lu WY
MA5-12178 was used in immunohistochemistry to investigate the role of a GABAergic system in airway epithelium in mucus overproduction in asthma
Sun Jul 01 00:00:00 EDT 2007
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.
Nature
Seandel M,James D,Shmelkov SV,Falciatori I,Kim J,Chavala S,Scherr DS,Zhang F,Torres R,Gale NW,Yancopoulos GD,Murphy A,Valenzuela DM,Hobbs RM,Pandolfi PP,Rafii S
MA5-12178 was used in immunohistochemistry to investigate the markers for functional multipotent adult stem cells from mammalian testicles
Thu Sep 20 00:00:00 EDT 2007
Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses.
American journal of respiratory and critical care medicine
Dillard P,Wetsel RA,Drouin SM
MA5-12178 was used in immunocytochemistry to examine the regulation of mucin production in airway Clara cells
Fri Jun 15 00:00:00 EDT 2007
Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction.
The Journal of allergy and clinical immunology
Hallstrand TS,Debley JS,Farin FM,Henderson WR
MA5-12178 was used in ELISA to investigate the role of MUC5AC on bronchoconstriction pathogenesis
Tue May 01 00:00:00 EDT 2007
A morphometric study of mucins and small airway plugging in cystic fibrosis.
Thorax
Burgel PR,Montani D,Danel C,Dusser DJ,Nadel JA
MA5-12178 was used in immunohistochemistry to investigate the changes of small airway plugging and mucin expression in cystic fibrosis
Thu Feb 01 00:00:00 EST 2007
IL-13 regulates cilia loss and foxj1 expression in human airway epithelium.
American journal of respiratory cell and molecular biology
Gomperts BN,Kim LJ,Flaherty SA,Hackett BP
MA5-12178 was used in immunocytochemistry to study the role of IL-13 in regulating cilia loss and the expression of foxj1 in human airway epithelium
Sat Sep 01 00:00:00 EDT 2007
Maintenance of airway epithelium in acutely rejected orthotopic vascularized mouse lung transplants.
American journal of respiratory cell and molecular biology
Okazaki M,Gelman AE,Tietjens JR,Ibricevic A,Kornfeld CG,Huang HJ,Richardson SB,Lai J,Garbow JR,Patterson GA,Krupnick AS,Brody SL,Kreisel D
MA5-12178 was used in immunohistochemistry to investigate the fate of airway epithelial cells after allogeneic orthotopic lung transplantation
Sat Dec 01 00:00:00 EST 2007
Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas.
International journal of cancer
Wang Y,Gao J,Li Z,Jin Z,Gong Y,Man X
MA5-12178 was used in immunohistochemistry to investigate the expression profiles of mucins in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas
Sat Dec 15 00:00:00 EST 2007
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.
Development (Cambridge, England)
Que J,Okubo T,Goldenring JR,Nam KT,Kurotani R,Morrisey EE,Taranova O,Pevny LH,Hogan BL
MA5-12178 was used in immunohistochemistry to investigate the influence of Sox2 dosage on anterior foregut endoderm development
Sun Jul 01 00:00:00 EDT 2007
Human bronchial epithelial cell transcriptome: gene expression changes following acute exposure to whole cigarette smoke in vitro.
American journal of physiology. Lung cellular and molecular physiology
Maunders H,Patwardhan S,Phillips J,Clack A,Richter A
MA5-12178 was used in immunocytochemistry to examine the effect of cigarette smoke exposure on gene expression in human bronchial epithelial cells
Tue May 01 00:00:00 EDT 2007
A deficient TLR2 signaling promotes airway mucin production in Mycoplasma pneumoniae-infected allergic mice.
American journal of physiology. Lung cellular and molecular physiology
Wu Q,Martin RJ,Rino JG,Jeyaseelan S,Breed R,Chu HW
MA5-12178 was used in western blot to examine the regulatory role of TLR2 signaling in murine mucin production after Mycoplasma pneumoniae infection
Tue May 01 00:00:00 EDT 2007
Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice.
American journal of physiology. Lung cellular and molecular physiology
Mohsenin A,Mi T,Xia Y,Kellems RE,Chen JF,Blackburn MR
MA5-12178 was used in immunohistochemistry to investigate the role of A2A adenosine receptor in pulmonary inflammation and angiogenesis
Sat Sep 01 00:00:00 EDT 2007
Emergence of spasmolytic polypeptide-expressing metaplasia in Mongolian gerbils infected with Helicobacter pylori.
Laboratory investigation; a journal of technical methods and pathology
Yoshizawa N,Takenaka Y,Yamaguchi H,Tetsuya T,Tanaka H,Tatematsu M,Nomura S,Goldenring JR,Kaminishi M
MA5-12178 was used in immunohistochemistry to study the development of spasmolytic polypeptide-expressing metaplasia in Helicobacter pylori-infected Mongolian gerbils
Sat Dec 01 00:00:00 EST 2007
Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.
Journal of immunology (Baltimore, Md. : 1950)
Chapoval SP,Al-Garawi A,Lora JM,Strickland I,Ma B,Lee PJ,Homer RJ,Ghosh S,Coyle AJ,Elias JA
MA5-12178 was used in western blot to examine the role of inhibition of NF-kappaB activation in the effect of IL-13 on murine lung
Thu Nov 15 00:00:00 EST 2007
A novel role for IkappaB kinase (IKK) alpha and IKKbeta in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae.
Journal of immunology (Baltimore, Md. : 1950)
Ha U,Lim JH,Jono H,Koga T,Srivastava A,Malley R,Pagès G,Pouysségur J,Li JD
MA5-12178 was used in ELISA to study the role of IkappaB kinases in MUC5AC mucin induction by Streptococcus pneumoniae
Thu Feb 01 00:00:00 EST 2007
Regulation of mucin gene expression by CREB via a nonclassical retinoic acid signaling pathway.
Molecular and cellular biology
Kim SW,Hong JS,Ryu SH,Chung WC,Yoon JH,Koo JS
MA5-12178 was used in western blot to study the role of a retinoic pathway in the regulation of mucin gene expression by CREB
Mon Oct 01 00:00:00 EDT 2007
CD8+ T cells contribute to macrophage accumulation and airspace enlargement following repeated irritant exposure.
Experimental and molecular pathology
Borchers MT,Wesselkamper SC,Harris NL,Deshmukh H,Beckman E,Vitucci M,Tichelaar JW,Leikauf GD
MA5-12178 was used in ELISA to investigate the effect of CD8+ T cells on macrophage accumulation and airspace enlargement following repeated irritant exposure
Sat Dec 01 00:00:00 EST 2007
Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation.
Experimental cell research
Skowron-zwarg M,Boland S,Caruso N,Coraux C,Marano F,Tournier F
MA5-12178 was used in immunocytochemistry to investigate the role of the interleukin-13 in human airway epithelial cell differentiation
Sun Jul 15 00:00:00 EDT 2007
Effects of sulfur dioxide on the expressions of MUC5AC and ICAM-1 in airway of asthmatic rats.
Regulatory toxicology and pharmacology : RTP
Li R,Meng Z,Xie J
MA5-12178 was used in immunoprecipitation to examine the mechanism for the effect of sulfur dioxide on the airway of asthmatic rats
Wed Aug 01 00:00:00 EDT 2007
Differentiation of tracheal basal cells to ciliated cells and tissue reconstruction on the synthesized basement membrane substratum in vitro.
Connective tissue research
Hosokawa T,Betsuyaku T,Nishimura M,Furuyama A,Katagiri K,Mochitate K
MA5-12178 was used in immunocytochemistry to investigate the application of new culture substratum in airway tissue reconstitution in vitro
Fri Apr 27 00:00:00 EDT 2007
Nitric oxide induces MUC5AC mucin in respiratory epithelial cells through PKC and ERK dependent pathways.
Respiratory research
Song JS,Kang CM,Yoo MB,Kim SJ,Yoon HK,Kim YK,Kim KH,Moon HS,Park SH
MA5-12178 was used in ELISA to examine the mechanism for the effect of nitric oxide on respiratory epithelial mucin expression
Thu Mar 29 00:00:00 EDT 2007
Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils.
American journal of respiratory and critical care medicine
Hays SR,Fahy JV
MA5-12178 was used in immunohistochemistry to investigate the changes of mucous cells in cystic fibrosis
Wed Nov 01 00:00:00 EST 2006
Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals.
The Journal of clinical investigation
Tyner JW,Kim EY,Ide K,Pelletier MR,Roswit WT,Morton JD,Battaile JT,Patel AC,Patterson GA,Castro M,Spoor MS,You Y,Brody SL,Holtzman MJ
MA5-12178 was used in immunohistochemistry to study the therapeutic appraches for inhibiting airway mucous cell metaplasia
Wed Feb 01 00:00:00 EST 2006
ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
The Journal of clinical investigation
Lee PJ,Zhang X,Shan P,Ma B,Lee CG,Homer RJ,Zhu Z,Rincon M,Mossman BT,Elias JA
MA5-12178 was used in western blot to study the role of ERK1/2 mitogen-activated protein kinase in IL-13-induced lung inflammation and remodeling
Sun Jan 01 00:00:00 EST 2006
Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers.
Cancer research
Carolan BJ,Heguy A,Harvey BG,Leopold PL,Ferris B,Crystal RG
MA5-12178 was used in immunocytochemistry to investigate the expression of carboxyl-terminal hydrolyase L1 gene in human airway epithelium of cigarette smokers
Wed Nov 15 00:00:00 EST 2006
Persistent effects induced by IL-13 in the lung.
American journal of respiratory cell and molecular biology
Fulkerson PC,Fischetti CA,Hassman LM,Nikolaidis NM,Rothenberg ME
MA5-12178 was used in western blot to study the persistence of the IL-13-induced changes in the murine lung
Fri Sep 01 00:00:00 EDT 2006
Culture of murine nasal epithelia: model for cystic fibrosis.
American journal of physiology. Lung cellular and molecular physiology
Grubb BR,Rogers TD,Diggs PC,Boucher RC,Ostrowski LE
MA5-12178 was used in immunohistochemistry to develop a method for the culture of primary murine nasal epithelia as a model for cystic fibrosis
Wed Feb 01 00:00:00 EST 2006
Peroxisome proliferator-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells.
American journal of physiology. Lung cellular and molecular physiology
Lee SY,Kang EJ,Hur GY,Jung KH,Jung HC,Lee SY,Kim JH,Shin C,In KH,Kang KH,Yoo SH,Shim JJ
MA5-12178 was used in ELISA to study the role of PPAR-gamma in inhibiting cigarette smoke solution-induced mucin production in human airway epithelial cells
Sat Jul 01 00:00:00 EDT 2006
MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.
The American journal of pathology
Finzi L,Barbu V,Burgel PR,Mergey M,Kirkwood KS,Wick EC,Scoazec JY,Peschaud F,Paye F,Nadel JA,Housset C
Published figure using MUC5AC monoclonal antibody (Product # MA5-12178) in Immunohistochemistry
Fri Dec 01 00:00:00 EST 2006
Cigarette smoke extract modulates respiratory defence mechanisms through effects on T-cells and airway epithelial cells.
Respiratory medicine
Glader P,Möller S,Lilja J,Wieslander E,Löfdahl CG,von Wachenfeldt K
MA5-12178 was used in ELISA to investigate the influence of cigarette smoke extract on the defence mechanisms of T-cells and epithelial cells
Mon May 01 00:00:00 EDT 2006
The inhibitory effects of rebamipide on cigarette smoke-induced airway mucin production.
Respiratory medicine
Lee SY,Kang EJ,Hur GY,Jung KH,Jung HC,Lee SY,Kim JH,Shin C,In KH,Kang KH,Yoo SH,Shim JJ
MA5-12178 was used in western blot to study the inhibitory effects of rebamipide on cigarette smoke-induced airway mucin production
Wed Mar 01 00:00:00 EST 2006
Effects of Helicobacter pylori infection on mucin expression in gastric carcinoma and pericancerous tissues.
Journal of gastroenterology and hepatology
Wang RQ,Fang DC
MA5-12178 was used in immunohistochemistry to study the role of Helicobacter pylori infection on the pathogenesis of gastric carcinoma
Wed Feb 01 00:00:00 EST 2006
Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.
Physiological genomics
Patel AC,Morton JD,Kim EY,Alevy Y,Swanson S,Tucker J,Huang G,Agapov E,Phillips TE,Fuentes ME,Iglesias A,Aud D,Allard JD,Dabbagh K,Peltz G,Holtzman MJ
MA5-12178 was used in immunohistochemistry to identify the genes involved in the complex airway disease traits
Tue May 16 00:00:00 EDT 2006
Rhamnolipids are virulence factors that promote early infiltration of primary human airway epithelia by Pseudomonas aeruginosa.
Infection and immunity
Zulianello L,Canard C,Köhler T,Caille D,Lacroix JS,Meda P
MA5-12178 was used in immunohistochemistry to investigate the mechanism for the invasion of human epithelia by Pseudomonas aeruginosa
Thu Jun 01 00:00:00 EDT 2006
A three-dimensional model of differentiation of immortalized human bronchial epithelial cells.
Differentiation; research in biological diversity
Vaughan MB,Ramirez RD,Wright WE,Minna JD,Shay JW
MA5-12178 was used in immunohistochemistry to examine the differentiation potential of immortalized human bronchial epithelial cells
Sat Apr 01 00:00:00 EST 2006
An enzyme-linked immunosorbent assay (ELISA) for the determination of mucin levels in bronchoalveolar lavage fluid.
Journal of pharmacological and toxicological methods
Phillips JE,Case NR,Celly C,Chapman RW,Hey JA,Minnicozzi M
MA5-12178 was used in ELISA to evaluate an assay for the measurement of mucin levels in bronchoalveolar lavage fluid
Tue Jul 18 00:00:00 EDT 2006
Effect of fibroblasts on tracheal epithelial regeneration in vitro.
Tissue engineering
Kobayashi K,Nomoto Y,Suzuki T,Tada Y,Miyake M,Hazama A,Kanemaru S,Nakamura T,Omori K
MA5-12178 was used in immunohistochemistry to study the effect of fibroblasts on tracheal epithelial regeneration during co-culture
Fri Sep 01 00:00:00 EDT 2006
Promoter analysis and aberrant expression of the MUC5B gene in diffuse panbronchiolitis.
American journal of respiratory and critical care medicine
Kamio K,Matsushita I,Hijikata M,Kobashi Y,Tanaka G,Nakata K,Ishida T,Tokunaga K,Taguchi Y,Homma S,Nakata K,Azuma A,Kudoh S,Keicho N
MA5-12178 was used in immunohistochemistry to study the involvement of MUC5B gene in diffuse panbronchiolitis
Sun May 01 00:00:00 EDT 2005
Effect of suplatast tosilate on goblet cell metaplasia in patients with asthma.
Allergy
Hoshino M,Fujita Y,Saji J,Inoue T,Nakagawa T,Miyazawa T
MA5-12178 was used in immunohistochemistry to investigate the role of suplatast tosilate in goblet cell metaplasia in patients with asthma
Tue Nov 01 00:00:00 EST 2005
Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm.
Clinical cancer research : an official journal of the American Association for Cancer Research
Dennis JL,Hvidsten TR,Wit EC,Komorowski J,Bell AK,Downie I,Mooney J,Verbeke C,Bellamy C,Keith WN,Oien KA
MA5-12178 was used in immunohistochemistry to identify markers of adenocarcinoma characteristic of the site of origin and develop a diagnostic algorithm
Sun May 15 00:00:00 EDT 2005
Tissue microarray analysis of multiple gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach.
Histopathology
Sun Y,Li JY,He JS,Zhou LX,Chen K
MA5-12178 was used in immunohistochemistry to investigate the gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach
Sun May 01 00:00:00 EDT 2005
Gefitinib inhibits MUC5AC synthesis in mucin-secreting non-small cell lung cancer cells.
Lung cancer (Amsterdam, Netherlands)
Kitazaki T,Soda H,Doi S,Nakano H,Nakamura Y,Kohno S
MA5-12178 was used in ELISA to study the effect of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in MUC5AC expression in non-small cell lung cancer cells
Sat Oct 01 00:00:00 EDT 2005
E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology
Kim S,Schein AJ,Nadel JA
MA5-12178 was used in immunocytochemistry to investigate the role of E-cadherin in the epidermal growth factor receptor-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells
Thu Dec 01 00:00:00 EST 2005
Effects of dexamethasone on Muc5ac mucin production by primary airway goblet cells.
American journal of physiology. Lung cellular and molecular physiology
Lu W,Lillehoj EP,Kim KC
MA5-12178 was used in ELISA to investigate the influence of dexamethasone on Muc5ac production in primary airway goblet cells
Sat Jan 01 00:00:00 EST 2005
Mucin biosynthesis: upregulation of core 2 beta 1,6 N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line.
American journal of physiology. Lung cellular and molecular physiology
Beum PV,Basma H,Bastola DR,Cheng PW
MA5-12178 was used in western blot to study the effect of retinoic acid and Th2 cytokines on mucin glycosylation in a human airway epithelial cell line
Sat Jan 01 00:00:00 EST 2005
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism.
The American journal of pathology
Park JA,He F,Martin LD,Li Y,Chorley BN,Adler KB
MA5-12178 was used in ELISA to study the effect of human neutrophil elastase on mucin secretion from human bronchial epithelial cells in vitro
Thu Sep 01 00:00:00 EDT 2005
Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF alpha-converting enzyme activity in airway epithelial cells.
The FEBS journal
Chokki M,Eguchi H,Hamamura I,Mitsuhashi H,Kamimura T
MA5-12178 was used in ELISA to investigate the role of human airway trypsin-like protease in the release of amphiregulin by human airway epithelial cells
Thu Dec 01 00:00:00 EST 2005
Differences in biological features of gastric dysplasia, indefinite dysplasia, reactive hyperplasia and discriminant analysis of these lesions.
World journal of gastroenterology
Dong B,Xie YQ,Chen K,Wang T,Tang W,You WC,Li JY
MA5-12178 was used in immunohistochemistry to investigate the characteristics of gastric, indefinite, and reactive hyperplasia
Tue Jun 21 00:00:00 EDT 2005
pH-dependent intraluminal organization of mucin granules in live human mucous/goblet cells.
The Journal of biological chemistry
Perez-Vilar J,Olsen JC,Chua M,Boucher RC
MA5-12178 was used in immunocytochemistry to investigate the influence of pH on mucin granule organization in mucous/goblet
Fri Apr 29 00:00:00 EDT 2005
Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps.
The European respiratory journal
Burgel PR,Cardell LO,Ueki IF,Nadel JA
MA5-12178 was used in immunohistochemistry to investigate the influence of intranasal steroids on specific gene expression in nasal polyps
Fri Oct 01 00:00:00 EDT 2004
Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression.
The American journal of surgical pathology
Rossi G,Murer B,Cavazza A,Losi L,Natali P,Marchioni A,Migaldi M,Capitanio G,Brambilla E
MA5-12178 was used in immunohistochemistry to report the clinicopathologic and immunohistochemical features of primary mucinous carcinomas of the lung
Thu Apr 01 00:00:00 EST 2004
PMA induces the MUC5AC respiratory mucin in human bronchial epithelial cells, via PKC, EGF/TGF-alpha, Ras/Raf, MEK, ERK and Sp1-dependent mechanisms.
Journal of molecular biology
Hewson CA,Edbrooke MR,Johnston SL
MA5-12178 was used in ELISA to investigate the effect of PMA on MUC5AC respiratory mucin
Fri Nov 26 00:00:00 EST 2004
Differentiation-dependent responsiveness of bronchial epithelial cells to IL-4/13 stimulation.
American journal of physiology. Lung cellular and molecular physiology
Kikuchi T,Shively JD,Foley JS,Drazen JM,Tschumperlin DJ
MA5-12178 was used in immunocytochemistry to study the response of bronchial epithelial cells to IL-4 and IL-13 and the influence of differentiation status
Thu Jul 01 00:00:00 EDT 2004
Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia.
American journal of physiology. Lung cellular and molecular physiology
Gray T,Coakley R,Hirsh A,Thornton D,Kirkham S,Koo JS,Burch L,Boucher R,Nettesheim P
MA5-12178 was used in immunocytochemistry to study the effect of IL-1beta on MUC5AC mucin secretion and airway surface liquid metabolism in human bronchial epithelia
Sun Feb 01 00:00:00 EST 2004
Azithromycin inhibits MUC5AC production induced by the Pseudomonas aeruginosa autoinducer N-(3-Oxododecanoyl) homoserine lactone in NCI-H292 Cells.
Antimicrobial agents and chemotherapy
Imamura Y,Yanagihara K,Mizuta Y,Seki M,Ohno H,Higashiyama Y,Miyazaki Y,Tsukamoto K,Hirakata Y,Tomono K,Kadota J,Kohno S
MA5-12178 was used in ELISA to investigate the effect of azithromycin on MUC5AC production in NCI-H292 cells
Wed Sep 01 00:00:00 EDT 2004
Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma.
The American journal of pathology
Chu HW,Balzar S,Seedorf GJ,Westcott JY,Trudeau JB,Silkoff P,Wenzel SE
MA5-12178 was used in western blot to investigate the influence of tumor growth factor beta 2 on mucin expression in asthma
Fri Oct 01 00:00:00 EDT 2004
A mouse model for the study of recurrent corneal epithelial erosions: alpha9beta1 integrin implicated in progression of the disease.
Investigative ophthalmology & visual science
Pal-Ghosh S,Pajoohesh-Ganji A,Brown M,Stepp MA
MA5-12178 was used in immunohistochemistry to evaluate an invivo mouse model for the study of recurrent corneal epithelial erosions
Tue Jun 01 00:00:00 EDT 2004
Correlation between MUC5AC expression and the prognosis of patients with adenocarcinoma of the uterine cervix.
Annals of surgical oncology
Mitsuhashi A,Yamazawa K,Nagai Y,Tanaka N,Matsui H,Sekiya S
MA5-12178 was used in immunohistochemistry to study the prognostic value of MUC5AC expression in adenocarcinomas of the uterine cervix
Thu Jan 01 00:00:00 EST 2004
Reduced airway inflammation and remodeling in parallel with mucin 5AC protein expression decreased by s-carboxymethylcysteine, a mucoregulant, in the airways of rats exposed to sulfur dioxide.
International archives of allergy and immunology
Sueyoshi S,Miyata Y,Masumoto Y,Ishibashi Y,Matsuzawa S,Harano N,Tsuru K,Imai S
MA5-12178 was used in immunohistochemistry to investigate the influence of S-carboxymethylcysteine on airway inflammation, mucus cells and MUC5AC expression in a rat model
Sun Aug 01 00:00:00 EDT 2004
Relationship between MUC5AC and altered expression of MLH1 protein in mucinous and non-mucinous colorectal carcinomas.
Pathology, research and practice
Losi L,Scarselli A,Benatti P,Ponz de Leon M,Roncucci L,Pedroni M,Borghi F,Lamberti I,Rossi G,Marino M,Ponti G,Zangardi G,Menigatti M,Di Gregorio C
MA5-12178 was used in immunohistochemistry to study the association of MUC5AC with altered expression of MLH1 protein in mucinous and non-mucinous colorectal carcinomas
Thu Dec 23 00:00:00 EST 2004
Differentiated cultures of primary hamster tracheal airway epithelial cells.
In vitro cellular & developmental biology. Animal
Rowe RK,Brody SL,Pekosz A
MA5-12178 was used in immunocytochemistry to generate and characterize primary airway epithelial cell cultures from Syrian golden hamsters
Thu May 05 00:00:00 EDT 2005
Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway.
The Journal of clinical investigation
Blackburn MR,Lee CG,Young HW,Zhu Z,Chunn JL,Kang MJ,Banerjee SK,Elias JA
MA5-12178 was used in western blot to study the role of adenosine in the effect of interleukin 13 in inflammation and remodeling in lungs
Fri Aug 01 00:00:00 EDT 2003
Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach.
Oncogene
Oien KA,Vass JK,Downie I,Fullarton G,Keith WN
MA5-12178 was used in immunohistochemistry to investigate the diagnostic and prognostic markers for gastric carcinoma
Thu Jul 03 00:00:00 EDT 2003
IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation.
American journal of physiology. Lung cellular and molecular physiology
Atherton HC,Jones G,Danahay H
MA5-12178 was used in immunocytochemistry to investigate the influence of interleukin 13 on human bronchial epithelial cell cultures and its mechanism
Mon Sep 01 00:00:00 EDT 2003
Alterations of MUC1 and MUC3 expression in gastric carcinoma: relevance to patient clinicopathological features.
Journal of clinical pathology
Wang RQ,Fang DC
MA5-12178 was used in immunohistochemistry to investigate the expression of MUC1 and MUC3 in gastric carcinoma
Thu May 01 00:00:00 EDT 2003
Ozone exposure enhances endotoxin-induced mucous cell metaplasia in rat pulmonary airways.
Toxicological sciences : an official journal of the Society of Toxicology
Wagner JG,Van Dyken SJ,Wierenga JR,Hotchkiss JA,Harkema JR
MA5-12178 was used in ELISA to study the effects of ozone and endotoxin co-exposure on mucous cell metaplasia in rat pulmonary airways
Fri Aug 01 00:00:00 EDT 2003
Role of MUC1 and MUC5AC expressions as prognostic indicators in gastric carcinomas.
Journal of surgical oncology
Wang JY,Chang CT,Hsieh JS,Lee LW,Huang TJ,Chai CY,Lin SR
MA5-12178 was used in immunohistochemistry to study the prognostic significance of MUC1 and MUC5AC expression in gastric cancer
Fri Aug 01 00:00:00 EDT 2003
Increased expression of the human Ca2+-activated Cl- channel 1 (CaCC1) gene in the asthmatic airway.
American journal of respiratory and critical care medicine
Hoshino M,Morita S,Iwashita H,Sagiya Y,Nagi T,Nakanishi A,Ashida Y,Nishimura O,Fujisawa Y,Fujino M
MA5-12178 was used in immunohistochemistry to investigate the expression of calcium-activated chloride channel 1 in the asthmatic airway and its role in asthmatic pathogenesis
Mon Apr 15 00:00:00 EDT 2002
Viral induction of a chronic asthma phenotype and genetic segregation from the acute response.
The Journal of clinical investigation
Walter MJ,Morton JD,Kajiwara N,Agapov E,Holtzman MJ
MA5-12178 was used in immunohistochemistry to characterize the a chronic asthma phenotype induced by paramyxoviruses
Mon Jul 01 00:00:00 EDT 2002
Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation.
American journal of physiology. Lung cellular and molecular physiology
Kohri K,Ueki IF,Nadel JA
MA5-12178 was used in immunocytochemistry to investigate the mechanism by which neutrophil elastase induces mucin production
Sun Sep 01 00:00:00 EDT 2002
Effect of gefarnate on the ocular surface in squirrel monkeys.
Cornea
Toshida H,Nakata K,Hamano T,Nakamura M,Nguyen D,Beuerman RW
MA5-12178 was used in western blot to study the ability of gefarnate to stimulate goblet cell function in the primate eye after a mild alkali injury of the tarsal conjunctiva
Mon Apr 01 00:00:00 EST 2002
Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways.
The Journal of biological chemistry
Lee CG,Homer RJ,Cohn L,Link H,Jung S,Craft JE,Graham BS,Johnson TR,Elias JA
MA5-12178 was used in western blot to investigate the effect of interleukin 10 expression on mucus production, inflammatory response, and airway integrity
Fri Sep 20 00:00:00 EDT 2002
Ethanol vapour-fixation of rat lung for immunocytochemistry investigations.
Journal of immunological methods
Wilson HH,Chauhan J,Kerry PJ,Evans JG
MA5-12178 was used in immunohistochemistry to evaluate a novel fixation method for lung tissue
Mon Jan 01 00:00:00 EST 2001
Selective secretion and replenishment of discrete mucin glycoforms from intestinal goblet cells.
The American journal of physiology
Stanley CM,Phillips TE
MA5-12178 was used in immunocytochemistry to investigate production and secretion and of mucin glycoforms in HT29-18N2 cells
Thu Jul 01 00:00:00 EDT 1999
