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Product Details
H00727897-M01A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
8C11
Immunogen
MUC5B (XP_039877.9, 4186 a.a. approximately 4295 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: CEEDSCQVRI NTTILWHQGC ETEVNITFCE GSCPGASKYS AEAQAMQHQC TCCQERRVHE ETVPLHCPNG SAILHTYTHV DECGCTPFCV PAPMAPPHTR GFPAQEATAV
Target Information
Mucins (MUCs) are heavily glycosylated glycoproteins that are synthesized either as membrane-bound or secreted proteins. Mucins are noteworthy because they have an aberrant expression profile in various malignancies. Mucins normally play a protective role for epithelial tissues and are expressed in the gastrointestinal, respiratory, and genito-urinary tracts. Mucins may also be involved in the renewal and differentiation of the epithelium, and the modulation of cell adhesion and cell signaling. MUC5B is thought to play a vital role in maintaining oral health, and may also be involved in respiratory and oral disease.2 MUC5B expression has been studied in gastric carcinoma as well as chronic obstructive pulmonary disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cervical mucin; cervical mucin MUC5B; High molecular weight salivary mucin MG1; MUC-5B; mucin 5, subtype B, tracheobronchial; Mucin-5 subtype B, tracheobronchial; Mucin-5B; Sublingual gland mucin
Gene Aliases: MG1; MUC-5B; MUC5; MUC5B; MUC9
UniProt ID: (Human) Q9HC84
Entrez Gene ID: (Human) 727897
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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