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MUPP1 Polyclonal Antibody

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Datasheet

Protocols

Questions & Answers

Tech Support

Product Details

OSM00105W-100UL

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

Immunohistochemistry (IHC)

1:300-1:2,000

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 1100-1200 of human MUPP1 conjugated to an immunogenic carrier protein was used as the antigen

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: MUPP1.

Target Information

MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor1, and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus. MUPP1 contains 13 PDZ domains but no apparent catalytic domain. MUPP1 is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM). MUPP1 may therefore function as a multivalent scaffold protein that recruits various proteins to tight junctions. MUPP1 also interacts with claudin-8 and may play a role in tight junction barrier function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

DNA sequence and analysis of human chromosome 9.

Nature

Humphray SJ,Oliver K,Hunt AR,Plumb RW,Loveland JE,Howe KL,Andrews TD,Searle S,Hunt SE,Scott CE,Jones MC,Ainscough R,Almeida JP,Ambrose KD,Ashwell RI,Babbage AK,Babbage S,Bagguley CL,Bailey J,Banerjee R,Barker DJ,Barlow KF,Bates K,Beasley H,Beasley O,Bird CP,Bray-Allen S,Brown AJ,Brown JY,Burford D,Burrill W,Burton J,Carder C,Carter NP,Chapman JC,Chen Y,Clarke G,Clark SY,Clee CM,Clegg S,Collier RE,Corby N,Crosier M,Cummings AT,Davies J,Dhami P,Dunn M,Dutta I,Dyer LW,Earthrowl ME,Faulkner L,Fleming CJ,Frankish A,Frankland JA,French L,Fricker DG,Garner P,Garnett J,Ghori J,Gilbert JG,Glison C,Grafham DV,Gribble S,Griffiths C,Griffiths-Jones S,Grocock R,Guy J,Hall RE,Hammond S,Harley JL,Harrison ES,Hart EA,Heath PD,Henderson CD,Hopkins BL,Howard PJ,Howden PJ,Huckle E,Johnson C,Johnson D,Joy AA,Kay M,Keenan S,Kershaw JK,Kimberley AM,King A,Knights A,Laird GK,Langford C,Lawlor S,Leongamornlert DA,Leversha M,Lloyd C,Lloyd DM,Lovell J,Martin S,Mashreghi-Mohammadi M,Matthews L,McLaren S,McLay KE,McMurray A,Milne S,Nickerson T,Nisbett J,Nordsiek G,Pearce AV,Peck AI,Porter KM,Pandian R,Pelan S,Phillimore B,Povey S,Ramsey Y,Rand V,Scharfe M,Sehra HK,Shownkeen R,Sims SK,Skuce CD,Smith M,Steward CA,Swarbreck D,Sycamore N,Tester J,Thorpe A,Tracey A,Tromans A,Thomas DW,Wall M,Wallis JM,West AP,Whitehead SL,Willey DL,Williams SA,Wilming L,Wray PW,Young L,Ashurst JL,Coulson A,Blöcker H,Durbin R,Sulston JE,Hubbard T,Jackson MJ,Bentley DR,Beck S,Rogers J,Dunham I

Thu May 27 00:00:00 EDT 2004

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nature genetics

Ota T,Suzuki Y,Nishikawa T,Otsuki T,Sugiyama T,Irie R,Wakamatsu A,Hayashi K,Sato H,Nagai K,Kimura K,Makita H,Sekine M,Obayashi M,Nishi T,Shibahara T,Tanaka T,Ishii S,Yamamoto J,Saito K,Kawai Y,Isono Y,Nakamura Y,Nagahari K,Murakami K,Yasuda T,Iwayanagi T,Wagatsuma M,Shiratori A,Sudo H,Hosoiri T,Kaku Y,Kodaira H,Kondo H,Sugawara M,Takahashi M,Kanda K,Yokoi T,Furuya T,Kikkawa E,Omura Y,Abe K,Kamihara K,Katsuta N,Sato K,Tanikawa M,Yamazaki M,Ninomiya K,Ishibashi T,Yamashita H,Murakawa K,Fujimori K,Tanai H,Kimata M,Watanabe M,Hiraoka S,Chiba Y,Ishida S,Ono Y,Takiguchi S,Watanabe S,Yosida M,Hotuta T,Kusano J,Kanehori K,Takahashi-Fujii A,Hara H,Tanase TO,Nomura Y,Togiya S,Komai F,Hara R,Takeuchi K,Arita M,Imose N,Musashino K,Yuuki H,Oshima A,Sasaki N,Aotsuka S,Yoshikawa Y,Matsunawa H,Ichihara T,Shiohata N,Sano S,Moriya S,Momiyama H,Satoh N,Takami S,Terashima Y,Suzuki O,Nakagawa S,Senoh A,Mizoguchi H,Goto Y,Shimizu F,Wakebe H,Hishigaki H,Watanabe T,Sugiyama A,Takemoto M,Kawakami B,Yamazaki M,Watanabe K,Kumagai A,Itakura S,Fukuzumi Y,Fujimori Y,Komiyama M,Tashiro H,Tanigami A,Fujiwara T,Ono T,Yamada K,Fujii Y,Ozaki K,Hirao M,Ohmori Y,Kawabata A,Hikiji T,Kobatake N,Inagaki H,Ikema Y,Okamoto S,Okitani R,Kawakami T,Noguchi S,Itoh T,Shigeta K,Senba T,Matsumura K,Nakajima Y,Mizuno T,Morinaga M,Sasaki M,Togashi T,Oyama M,Hata H,Watanabe M,Komatsu T,Mizushima-Sugano J,Satoh T,Shirai Y,Takahashi Y,Nakagawa K,Okumura K,Nagase T,Nomura N,Kikuchi H,Masuho Y,Yamashita R,Nakai K,Yada T,Nakamura Y,Ohara O,Isogai T,Sugano S

Thu Jan 01 00:00:00 EST 2004

Bioinformatics

Protein Aliases: DKFZp781P216; FLJ25909; FLJ34626; FLJ90240; Multi-PDZ domain protein 1; Multiple PDZ domain protein

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Gene Aliases: HYC2; MPDZ; MUPP1

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UniProt ID: (Human) O75970

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Entrez Gene ID: (Human) 8777

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Function(s)

protein binding protein C-terminus binding

Process(es)

cell adhesion viral process myelination

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MUPP1 Polyclonal Antibody

Product Details

OSM00105W-100UL

Western Blot (WB)

Immunohistochemistry (IHC)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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