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Product Details
PA5-54168
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MUPP1. Recombinant protein control fragment (Product #RP-92907).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644306
Product Specific Information
Immunogen sequence: VVNILKELPI EVTMVCCRRT VPPTTQSELD SLDLCDIELT EKPHVDLGEF IGSSETEDPV LAMTDAGQST EEVQAPLAMW EAGIQHIELE KGSKGLGFS
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 82%.
Target Information
MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor1, and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus. MUPP1 contains 13 PDZ domains but no apparent catalytic domain. MUPP1 is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM). MUPP1 may therefore function as a multivalent scaffold protein that recruits various proteins to tight junctions. MUPP1 also interacts with claudin-8 and may play a role in tight junction barrier function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781P216; FLJ25909; FLJ34626; FLJ90240; Multi-PDZ domain protein 1; Multiple PDZ domain protein
Gene Aliases: HYC2; MPDZ; MUPP1
UniProt ID: (Human) O75970
Entrez Gene ID: (Human) 8777
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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