Search Thermo Fisher Scientific
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Immunogen sequence: MDPVPGTDSA PLAGLAWSSA SAPPPRGFSA ISCTVEGAPA SFGKSFAQKS GYFLCLSSLG SLENPQENVV ADIQIVVDKS PLPLGFSPVC DPMDSKASVS KKKRMCVKLL PLGATDTAVF DVRLSGKTKT VPGYLRIGDM GGFAIWCKKA KAPRPVPKPR GLSRDMQGLS LDAASQPSKG GLLERTASRL GSRASTLRRN DSIYEASSLY GISAMDGVPF TLHPRFEGKS CSPLAFSAFG DLTIKSLADI EEEYNYGFVV EKTAAARLPP SVS; Positive Samples: Rat pancreas; Cellular Location: Cytoplasm, Endosome, Late endosome membrane, Nucleus, Peripheral membrane protein, centrosome, cytoskeleton, microtubule organizing center
FAM125A, also named as MVB12A and CFBP, is a component of the ESCRT-I complex. FAM125A is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. FAM125A has three isoforms with MW 27-28 kDa and 25 kDa.
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Protein Aliases: ESCRT-I complex subunit MVB12A; family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A
Gene Aliases: Fam125a; Mvb12a
UniProt ID: (Rat) Q6P777
Entrez Gene ID: (Rat) 290635
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