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Search Thermo Fisher Scientific
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Immunogen sequence: RLQPHSNGKV DLSLPNIGIK RAWDVARLQS LDTSFLEQGD VTTPTSEQVE KLKEVAGLPD DCAVTERLAV LAFLYLYLSI CRKQRALPSL DIVVWSELPP GAGLGSSAAY SVCLAAALLT VCEEIPNPLK DGDCVNRWTK EDLELINKWA FQGERMIHGN PSGVDNAVST WGGALRYHQG KISSLKRSPA LQILLTNTKV PRNTRALVAG VRNRLLKFPE IVAPLLTSID AISLECERVL GEMGEAPAPE QYLVLEELID M; Positive Samples: Raji, BT-474; Cellular Location: Cytoplasm
Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Deficiency in MVK activity contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).
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Protein Aliases: KIME; LH receptor mRNA-binding protein; Mevalonate kinase; mevalonate kinase 1; MK
Gene Aliases: LRBP; MK; MVK; MVLK; POROK3
UniProt ID: (Human) Q03426
Entrez Gene ID: (Human) 4598
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