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Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (92%), Rat (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The gene MYBPC2 belongs to the myosin-binding protein C family, which consists of fast-, slow-, and cardiac-type isoforms. These isoforms are myosin-associated proteins that are located in the C region of A bands in striated muscle. The protein encoded by MYBPC2 is the fast-type isoform. Mutations in genes encoding the slow-type and cardiac-type isoforms have been linked to distal arthrogryposis, type 1, and hypertrophic cardiomyopathy, respectively. MYBPC2-related diseases include Lethal Congenital Contracture Syndrome 4 and Nemaline Myopathy 9.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-protein, skeletal muscle fast isoform; Fast MyBP-C; fast-type muscle myosin-binding-protein C; Myosin-binding protein C, fast-type; mypc2; testicular tissue protein Li 126
Gene Aliases: MYBPC; MYBPC2; MYBPCF
UniProt ID: (Human) Q14324
Entrez Gene ID: (Human) 4606
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