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Product Details
PA5-120254
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human MYL2 (NP_0004232)
Conjugate
Form
Liquid
Concentration
0.87 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913826
Product Specific Information
Positive test controls include: Mouse heart, Mouse skeletal muscle, Rat heart, Rat skeletal muscle. The target is usually found in the following locations: A band, Cytoplasm, myofibril, sarcomere.
Immunogen sequence: MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL DYKNLVHIIT HGEEKD
Target Information
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac myosin light chain-2; DKFZp779C0562; MLC-2; MLC-2s/v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2v; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light polypeptide 2, regulatory, cardiac, slow; ventricular myosin regulatory light chain
Gene Aliases: MLC-2; MLC-2v; Mlc2; Mlc2v; Myl2; Mylpc
UniProt ID: (Rat) P08733, (Mouse) P51667
Entrez Gene ID: (Rat) 363925, (Mouse) 17906
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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