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Product Details
MA5-32264
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SN67-09
Immunogen
Synthetic peptide within Human Myosin Light Chain 2 aa 117-166
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2809550
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC-2; MLC-2s/v; MLC-2v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2v; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin regulatory light chain 2b; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin, light polypeptide 2b, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; Ventricular myosin light chain 2; ventricular myosin regulatory light chain
Gene Aliases: CMH10; MLC-2; MLC-2s/v; MLC-2v; MLC2; mlc2b; Mlc2v; MYL2; Mylpc; zgc:136848
UniProt ID: (Human) P10916, (Rat) P08733, (Mouse) P51667
Entrez Gene ID: (Human) 4633, (Rat) 363925, (Mouse) 17906, (Zebrafish) 677750
regulation of the force of heart contraction
regulation of striated muscle contraction
heart development
post-embryonic development
muscle filament sliding
negative regulation of cell growth
muscle cell fate specification
muscle fiber development
cardiac myofibril assembly
ventricular cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
positive regulation of the force of heart contraction
heart morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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