Product References
Lack of STAT1 co-operative DNA binding protects against adverse cardiac remodelling in acute myocardial infarction.
Frontiers in cardiovascular medicine
Doudin A,Riebeling T,Staab J,Menon PR,Lühder F,Wirths O,Vinkemeier U,Ivetic A,Meyer T
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Thu Mar 16 00:00:00 EDT 2023
Ginsenoside Rg3-enriched Korean Red Ginseng extract attenuates Non-Alcoholic Fatty Liver Disease by way of suppressed VCAM-1 expression in liver sinusoidal endothelium.
Journal of ginseng research
Lee SW,Baek SM,Lee YJ,Kim TU,Yim JH,Son JH,Kim HY,Kang KK,Kim JH,Rhee MH,Park SJ,Choi SK,Park JK
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry (Paraffin)
Mon May 01 00:00:00 EDT 2023
Association between self-rated depressive symptoms and mucosal expression of NF-κ B in patients with upper gastrointestinal symptoms.
BioPsychoSocial medicine
Staab J,Vonhören L,Schwörer H,Meyer T
PA5-16672 was used in Immunohistochemistry to show a significant association between NF-κ B expression and clinically relevant depressive symptoms in patients with gastritis, as assessed by a self-rated psychometric questionnaire.
Sat Feb 25 00:00:00 EST 2023
Association between self-rated depressive symptoms and mucosal expression of NF-κ B in patients with upper gastrointestinal symptoms.
BioPsychoSocial medicine
Staab J,Vonhören L,Schwörer H,Meyer T
PA5-16672 was used in Immunohistochemistry to show a significant association between NF-κ B expression and clinically relevant depressive symptoms in patients with gastritis, as assessed by a self-rated psychometric questionnaire.
Sat Feb 25 00:00:00 EST 2023
NETosis induction reflects COVID-19 severity and long COVID: insights from a 2-center patient cohort study in Israel.
Journal of thrombosis and haemostasis : JTH
Krinsky N,Sizikov S,Nissim S,Dror A,Sas A,Prinz H,Pri-Or E,Perek S,Raz-Pasteur A,Lejbkowicz I,Cohen-Matsliah SI,Almog R,Chen N,Kurd R,Jarjou'i A,Rokach A,Ben-Chetrit E,Schroeder A,Caulin AF,Yost CC,Schiffman JD,Goldfeder M,Martinod K
PA5-16672 was used in Enzyme-linked immunosorbent assay to evaluate immunothrombosis markers in a comprehensive cohort of acute and recovered COVID-19 patients, including the association of NETs with long COVID.
Fri Sep 01 00:00:00 EDT 2023
Neutrophil inhibition improves acute inflammation in a murine model of viral myocarditis.
Cardiovascular research
Carai P,González LF,Van Bruggen S,Spalart V,De Giorgio D,Geuens N,Martinod K,Jones EAV,Heymans S
PA5-16672 was used in ELISA, Immunohistochemistry (Paraffin) to illustrate that repression of neutrophils and related NET response in acute phase of VM improves the pathological phenotype by reducing cardiac inflammation.
Wed Jan 18 00:00:00 EST 2023
Dual oxidase 1 is dispensable during Mycobacterium tuberculosis infection in mice.
Frontiers in immunology
Gupta T,Sarr D,Fantone K,Ashtiwi NM,Sakamoto K,Quinn FD,Rada B
PA5-16672 was used in Immunohistochemistry to demonstrate that while Duox1 might influence leukocyte recruitment to inflammatory cell aggregates, Duox1 is dispensable for the overall clinical course of Mtb lung infection in a mouse model.
Mon Mar 27 00:00:00 EDT 2023
Intragranuloma Accumulation and Inflammatory Differentiation of Neutrophils Underlie Mycobacterial ESX-1-Dependent Immunopathology.
mBio
Lienard J,Munke K,Wulff L,Da Silva C,Vandamme J,Laschanzky K,Joeris T,Agace W,Carlsson F
PA5-16672 was used in Immunohistochemistry-immunofluorescence to provide insight into how ESX-1 promotes disease, and they reveal an antagonistic functional relationship between monocytes and neutrophils that might regulate immunopathology not only in mycobacterial infection but also in other infections as well as in inflammatory conditions and cancer.
Tue Apr 25 00:00:00 EDT 2023
Th2 cells inhibit growth of colon and pancreas cancers by promoting anti-tumorigenic responses from macrophages and eosinophils.
British journal of cancer
Jacenik D,Karagiannidis I,Beswick EJ
PA5-16672 was used in Immunohistochemistry-immunofluorescence to demonstrate the significance of Th2 cells, eosinophils and IL-5 in the inhibition of gastrointestinal tumor growth, and pointed toward tumor microenvironment reprogramming as a Th2 cell-mediated anti-tumorigenic mechanism of action.
Sun Jan 01 00:00:00 EST 2023
Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model.
Respiratory research
Veras FP,Gomes GF,Silva BMS,Caetité DB,Almeida CJLR,Silva CMS,Schneider AH,Corneo ES,Bonilha CS,Batah SS,Martins R,Arruda E,Fabro AT,Alves-Filho JC,Cunha TM,Cunha FQ
PA5-16672 was used in ELISA, Immunohistochemistry (Paraffin) to support the role of neutrophil extracellular traps (NETs) in COVID-19 immunopathology and highlight NETs disruption pharmacological approaches as a potential strategy to ameliorate COVID-19 clinical outcomes.
Thu Mar 02 00:00:00 EST 2023
HMGB1-Mediated Neutrophil Extracellular Trap Formation Exacerbates Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury.
Journal of immunology (Baltimore, Md. : 1950)
Zhan Y,Ling Y,Deng Q,Qiu Y,Shen J,Lai H,Chen Z,Huang C,Liang L,Li X,Wu J,Huang W,Wen S
PA5-16672 was used in ELISA to conclude that the HMGB1 released from necroptotic enterocytes caused ALI after intestinal I/R by inducing NET formation.
Tue Feb 15 00:00:00 EST 2022
Ninjurin1 Deletion in NG2-Positive Pericytes Prevents Microvessel Maturation and Delays Wound Healing.
JID innovations : skin science from molecules to population health
Matsuo R,Kishibe M,Horiuchi K,Kano K,Tatsukawa T,Hayasaka T,Kabara M,Iinuma S,Eguchi R,Igawa S,Hasebe N,Ishida-Yamamoto A,Kawabe JI
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Tue Nov 01 00:00:00 EDT 2022
A novel aquaporin-4-associated optic neuritis rat model with severe pathological and functional manifestations.
Journal of neuroinflammation
Morita Y,Itokazu T,Nakanishi T,Hiraga SI,Yamashita T
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Thu Oct 27 00:00:00 EDT 2022
A novel aquaporin-4-associated optic neuritis rat model with severe pathological and functional manifestations.
Journal of neuroinflammation
Morita Y,Itokazu T,Nakanishi T,Hiraga SI,Yamashita T
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Thu Oct 27 00:00:00 EDT 2022
Mega-Dose Vitamin C Ameliorates Nonalcoholic Fatty Liver Disease in a Mouse Fast-Food Diet Model.
Nutrients
Lee SW,Lee YJ,Baek SM,Kang KK,Kim TU,Yim JH,Kim HY,Han SH,Choi SK,Park SJ,Kim TH,Park JK
PA5-16672 was used in Immunohistochemistry to suggest that the mega-dose vitamin C treatment suppresses high-fructose-diet-mediated NAFLD progression by decreasing diet ingestion and increasing water intake.
Wed May 25 00:00:00 EDT 2022
Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine.
Nature biomedical engineering
Wang Z,Popowski KD,Zhu D,de Juan Abad BL,Wang X,Liu M,Lutz H,De Naeyer N,DeMarco CT,Denny TN,Dinh PC,Li Z,Cheng K
PA5-16672 was used in Immunohistochemistry to report the design and preclinical testing of an inhalable virus-like-particle as a COVID-19 vaccine that, after lyophilisation, is stable at room temperature for over three months.
Fri Jul 01 00:00:00 EDT 2022
Alkaline sphingomyelinase (NPP7) impacts the homeostasis of intestinal T lymphocyte populations.
Frontiers in immunology
Alyamani M,Kadivar M,Erjefält J,Johansson-Lindbom B,Duan RD,Nilsson Å,Marsal J
PA5-16672 was used in ELISA, Immunohistochemistry (Paraffin) to conclude that alkaline sphingomyelinase (NPP7) contributes to the regulation of dendritic cell and T-lymphocyte numbers in mesenteric lymph nodes and both the small and large intestines, thus playing a role in the homeostasis of gut immunity.
Wed Feb 08 00:00:00 EST 2023
Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.
Cell reports
Veras FP,Publio GA,Melo BM,Prado DS,Norbiato T,Cecilio NT,Hiroki C,Damasceno LEA,Jung R,Toller-Kawahisa JE,Martins TV,Assunção SF,Lima D,Alves MG,Vieira GV,Tavares LA,Alves-Rezende ALR,Karbach SH,Nakaya HI,Cunha TM,Souza CS,Cunha FQ,Sales KU,Waisman A,Alves-Filho JC
PA5-16672 was used in ELISA, Immunohistochemistry (Paraffin) to reveal a sustained signaling circuit critical for the psoriasis-driving effects of IL-17A, suggesting that PKM2 is a potential therapeutic target for psoriasis.
Tue Dec 27 00:00:00 EST 2022
Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.
Cell reports
Veras FP,Publio GA,Melo BM,Prado DS,Norbiato T,Cecilio NT,Hiroki C,Damasceno LEA,Jung R,Toller-Kawahisa JE,Martins TV,Assunção SF,Lima D,Alves MG,Vieira GV,Tavares LA,Alves-Rezende ALR,Karbach SH,Nakaya HI,Cunha TM,Souza CS,Cunha FQ,Sales KU,Waisman A,Alves-Filho JC
PA5-16672 was used in ELISA, Immunohistochemistry (Paraffin) to reveal a sustained signaling circuit critical for the psoriasis-driving effects of IL-17A, suggesting that PKM2 is a potential therapeutic target for psoriasis.
Tue Dec 27 00:00:00 EST 2022
Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19.
EBioMedicine
Martens CP,Van Mol P,Wauters J,Wauters E,Gangnus T,Noppen B,Callewaert H,Feyen JHM,Liesenborghs L,Heylen E,Jansen S,Pereira LCV,Kraisin S,Guler I,Engelen MM,Ockerman A,Van Herck A,Vos R,Vandenbriele C,Meersseman P,Hermans G,Wilmer A,Martinod K,Burckhardt BB,Vanhove M,Jacquemin M,Verhamme P,Neyts J,Vanassche T
PA5-16672 was used in Enzyme-linked immunosorbent assay to suggest that dysregulation of the kallikrein-kinin system might occur in mechanically ventilated patients with severe pulmonary disease and severe COVID-19, resulting in pulmonary oedema and thromboembolic complications.
Thu Sep 01 00:00:00 EDT 2022
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis.
Cell death and differentiation
Hsu CG,Chávez CL,Zhang C,Sowden M,Yan C,Berk BC
PA5-16672 was used in Immunohistochemistry-immunofluorescence to identify HNE as a novel, endogenous inhibitor of the NLRP3 inflammasome.
Thu Sep 01 00:00:00 EDT 2022
d-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation.
Proceedings of the National Academy of Sciences of the United States of America
Wang J,Jalali Motlagh N,Wang C,Wojtkiewicz GR,Schmidt S,Chau C,Narsimhan R,Kullenberg EG,Zhu C,Linnoila J,Yao Z,Chen JW
PA5-16672 was used in Immunohistochemistry to suggest that d-mannose, an over-the-counter supplement with a high safety profile, may be a low-cost treatment option for neuroinflammatory diseases such as multiple sclerosis.
Tue Nov 02 00:00:00 EDT 2021
Phosphodiesterase 10A Is a Key Mediator of Lung Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Hsu CG,Fazal F,Rahman A,Berk BC,Yan C
PA5-16672 was used in Immunohistochemistry to understand the function of Phosphodiesterases in macrophages.
Tue Jun 15 00:00:00 EDT 2021
Hydrocephalus Induced by Intraventricular Peroxiredoxin-2: The Role of Macrophages in the Choroid Plexus.
Biomolecules
Chen T,Tan X,Xia F,Hua Y,Keep RF,Xi G
PA5-16672 was used in Immunohistochemistry-immunofluorescence to identify alterations in choroid plexus macrophages and dendritic cells following intracerebroventricular Prx2 injection and investigate the relationship between macrophages/dendritic cells and hydrocephalus.
Thu Apr 29 00:00:00 EDT 2021
Hydrocephalus Induced by Intraventricular Peroxiredoxin-2: The Role of Macrophages in the Choroid Plexus.
Biomolecules
Chen T,Tan X,Xia F,Hua Y,Keep RF,Xi G
PA5-16672 was used in Immunohistochemistry-immunofluorescence to identify alterations in choroid plexus macrophages and dendritic cells following intracerebroventricular Prx2 injection and investigate the relationship between macrophages/dendritic cells and hydrocephalus.
Thu Apr 29 00:00:00 EDT 2021
Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection.
JCI insight
Payne GA,Sharma NS,Lal CV,Song C,Guo L,Margaroli C,Viera L,Kumar S,Li J,Xing D,Bosley M,Xu X,Wells JM,George JF,Tallaj J,Leesar M,Blalock JE,Gaggar A
PA5-16672 was used in Immunohistochemistry (PFA fixed) to demonstrate that early acute cardiac rejection increases allograft prolyl endopeptidase (PE) in association with de novo production of the neutrophil proinflammatory matrikine proline-glycine-proline (PGP).
Mon Mar 22 00:00:00 EDT 2021
Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection.
JCI insight
Payne GA,Sharma NS,Lal CV,Song C,Guo L,Margaroli C,Viera L,Kumar S,Li J,Xing D,Bosley M,Xu X,Wells JM,George JF,Tallaj J,Leesar M,Blalock JE,Gaggar A
PA5-16672 was used in Immunohistochemistry (PFA fixed) to demonstrate that early acute cardiac rejection increases allograft prolyl endopeptidase (PE) in association with de novo production of the neutrophil proinflammatory matrikine proline-glycine-proline (PGP).
Mon Mar 22 00:00:00 EDT 2021
Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection.
JCI insight
Payne GA,Sharma NS,Lal CV,Song C,Guo L,Margaroli C,Viera L,Kumar S,Li J,Xing D,Bosley M,Xu X,Wells JM,George JF,Tallaj J,Leesar M,Blalock JE,Gaggar A
PA5-16672 was used in Immunohistochemistry (PFA fixed) to demonstrate that early acute cardiac rejection increases allograft prolyl endopeptidase (PE) in association with de novo production of the neutrophil proinflammatory matrikine proline-glycine-proline (PGP).
Mon Mar 22 00:00:00 EDT 2021
Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases.
Cellular and molecular gastroenterology and hepatology
Fang Z,Kim HG,Huang M,Chowdhury K,Li MO,Liangpunsakul S,Dong XC
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Tue Mar 22 00:00:00 EDT 2022
Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair.
Nature communications
Zhu D,Li Z,Huang K,Caranasos TG,Rossi JS,Cheng K
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunocytochemistry
Wed Mar 03 00:00:00 EST 2021
Immuno-phenotyping of IDH-mutant grade 3 astrocytoma and IDH-wildtype glioblastoma reveals specific differences in cells of myeloid origin.
Oncoimmunology
Raghavan JV,Ganesh RA,Sonpatki P,Naik D,John AE,Arunachalam P,Shah D,P S H,Lakshmikantha A,Pillai S,Chandrachari KP,Mariswamappa K,Lale S,Shah N,Jhunjhunwala S
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Fri Oct 15 00:00:00 EDT 2021
Immuno-phenotyping of IDH-mutant grade 3 astrocytoma and IDH-wildtype glioblastoma reveals specific differences in cells of myeloid origin.
Oncoimmunology
Raghavan JV,Ganesh RA,Sonpatki P,Naik D,John AE,Arunachalam P,Shah D,P S H,Lakshmikantha A,Pillai S,Chandrachari KP,Mariswamappa K,Lale S,Shah N,Jhunjhunwala S
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Fri Oct 15 00:00:00 EDT 2021
A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse.
Bioactive materials
Xie M,Li J,Zhang S,Zhu D,Mei X,Wang Z,Cheng X,Li Z,Wang S,Cheng K
PA5-16672 was used in Immunohistochemistry to fabricate a Carbomer-based contraceptive gel consisting of three agents: tenofovir, gossypol acetate, and nitroglycerin (TGN), with pH adjusted to 4.5 (to be compatible with the vagina).
Tue Jun 01 00:00:00 EDT 2021
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.
Nature communications
Vanderbeke L,Van Mol P,Van Herck Y,De Smet F,Humblet-Baron S,Martinod K,Antoranz A,Arijs I,Boeckx B,Bosisio FM,Casaer M,Dauwe D,De Wever W,Dooms C,Dreesen E,Emmaneel A,Filtjens J,Gouwy M,Gunst J,Hermans G,Jansen S,Lagrou K,Liston A,Lorent N,Meersseman P,Mercier T,Neyts J,Odent J,Panovska D,Penttila PA,Pollet E,Proost P,Qian J,Quintelier K,Raes J,Rex S,Saeys Y,Sprooten J,Tejpar S,Testelmans D,Thevissen K,Van Buyten T,Vandenhaute J,Van Gassen S,Velásquez Pereira LC,Vos R,Weynand B,Wilmer A,Yserbyt J,Garg AD,Matthys P,Wouters C,Lambrechts D,Wauters E,Wauters J
PA5-16672 was used in ELISA to suggest a myeloid-driven immunopathology, in which hyperactivated neutrophils and an ineffective adaptive immune system act as mediators of COVID-19 disease severity.
Mon Jul 05 00:00:00 EDT 2021
Complement Inhibition Alleviates Cholestatic Liver Injury Through Mediating Macrophage Infiltration and Function in Mice.
Frontiers in immunology
Guo Z,Chen J,Zeng Y,Wang Z,Yao M,Tomlinson S,Chen B,Yuan G,He S
PA5-16672 was used in Immunohistochemistry-frozen tissue to assess the role of complement in CLI and the therapeutic effect of the site-targeted complement inhibitor CR2-Crry in CLI.
Mon Feb 28 00:00:00 EST 2022
Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes.
NPJ Regenerative medicine
Petrigliano FA,Liu NQ,Lee S,Tassey J,Sarkar A,Lin Y,Li L,Yu Y,Geng D,Zhang J,Shkhyan R,Bogdanov J,Van Handel B,Ferguson GB,Lee Y,Hinderer S,Tseng KC,Kavanaugh A,Crump JG,Pyle AD,Schenke-Layland K,Billi F,Wang L,Lieberman J,Hurtig M,Evseenko D
PA5-16672 was used in Immunohistochemistry to describe the development, transcriptomic ontogenetic characterization and quality assessment at the single cell level, as well as the scaled manufacturing of an allogeneic human pluripotent stem cell-derived articular chondrocyte formulation that exhibits long-term functional repair of porcine articular cartilage.
Tue Nov 23 00:00:00 EST 2021
Core 1-derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer.
The Journal of experimental medicine
Liu F,Fu J,Bergstrom K,Shan X,McDaniel JM,McGee S,Bai X,Chen W,Xia L
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Mon Jan 06 00:00:00 EST 2020
Core 1-derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer.
The Journal of experimental medicine
Liu F,Fu J,Bergstrom K,Shan X,McDaniel JM,McGee S,Bai X,Chen W,Xia L
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Mon Jan 06 00:00:00 EST 2020
SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology.
The Journal of experimental medicine
Veras FP,Pontelli MC,Silva CM,Toller-Kawahisa JE,de Lima M,Nascimento DC,Schneider AH,Caetité D,Tavares LA,Paiva IM,Rosales R,Colón D,Martins R,Castro IA,Almeida GM,Lopes MIF,Benatti MN,Bonjorno LP,Giannini MC,Luppino-Assad R,Almeida SL,Vilar F,Santana R,Bollela VR,Auxiliadora-Martins M,Borges M,Miranda CH,Pazin-Filho A,da Silva LLP,Cunha LD,Zamboni DS,Dal-Pizzol F,Leiria LO,Siyuan L,Batah S,Fabro A,Mauad T,Dolhnikoff M,Duarte-Neto A,Saldiva P,Cunha TM,Alves-Filho JC,Arruda E,Louzada-Junior P,Oliveira RD,Cunha FQ
PA5-16672 was used in DNA binding to result unravel a possible detrimental role of NETs in the pathophysiology of COVID-19. Therefore, the inhibition of NETs represents a potential therapeutic target for COVID-19.
Mon Dec 07 00:00:00 EST 2020
Transgenic expression of GFP-LC3 perturbs autophagy in exocrine pancreas and acute pancreatitis responses in mice.
Autophagy
Mareninova OA,Jia W,Gretler SR,Holthaus CL,Thomas DDH,Pimienta M,Dillon DL,Gukovskaya AS,Gukovsky I,Groblewski GE
PA5-16672 was used in Immunohistochemistry to examine the effects of GFP-LC3 expression on autophagy, acinar cell function, and experimental pancreatitis.
Sun Nov 01 00:00:00 EDT 2020
Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage.
Stroke
Tan X,Chen J,Keep RF,Xi G,Hua Y
PA5-16672 was used in Immunohistochemistry to propose that peroxiredoxin contributes to intraventricular hemorrhage-induced hydrocephalus, probably by inducing inflammatory responses in choroid plexus and ventricular wall damage.
Fri May 01 00:00:00 EDT 2020
Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.
Translational stroke research
Bian L,Zhang J,Wang M,Keep RF,Xi G,Hua Y
PA5-16672 was used in Immunohistochemistry to show hematoma released extracellular PRX-2 can induce brain injury following brain hemorrhage.
Wed Apr 01 00:00:00 EDT 2020
Perinatal maternal antibiotic exposure augments lung injury in offspring in experimental bronchopulmonary dysplasia.
American journal of physiology. Lung cellular and molecular physiology
Willis KA,Siefker DT,Aziz MM,White CT,Mussarat N,Gomes CK,Bajwa A,Pierre JF,Cormier SA,Talati AJ
PA5-16672 was used in Immunohistochemistry to report that disruption of intestinal commensal colonization during the perinatal period promotes a more severe bronchopulmonary dysplasia phenotype characterized by increased mortality and pulmonary fibrosis.
Sat Feb 01 00:00:00 EST 2020
Attenuation of pulmonary injury by an inhaled MMP inhibitor in the endotoxin lung injury model.
American journal of physiology. Lung cellular and molecular physiology
Gerber A,Goldklang M,Stearns K,Ma X,Xiao R,Zelonina T,D'Armiento J
PA5-16672 was used in Immunohistochemistry to demonstrate that inhalation of a broad MMP inhibitor attenuates LPS induced pulmonary inflammation.
Tue Dec 01 00:00:00 EST 2020
Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik).
The American journal of pathology
Greenberg A,Huber BR,Liu DX,Logue JP,Hischak AMW,Hart RJ,Abbott M,Isic N,Hisada YM,Mackman N,Bennett RS,Hensley LE,Connor JH,Crossland NA
PA5-16672 was used in Immunohistochemistry to contribute to our current understanding of early EVD progression and illustrate the value that digital pathology and quantitative IA serve in infectious disease research.
Wed Jul 01 00:00:00 EDT 2020
Cryopreserved human skin allografts promote angiogenesis and dermal regeneration in a murine model.
International wound journal
Henn D,Chen K,Maan ZN,Greco AH,Moortgat Illouz SE,Bonham CA,Barrera JA,Trotsyuk AA,Padmanabhan J,Momeni A,Wan DC,Nguyen D,Januszyk M,Gurtner GC
PA5-16672 was used in Immunohistochemistry to indicate that CHSAs promote angiogenesis and collagen-1 production without eliciting a significant fibrotic response in a xenograft model.
Sat Aug 01 00:00:00 EDT 2020
Extracellular Traps Released by Neutrophils from Cats are Detrimental to Toxoplasma gondii Infectivity.
Microorganisms
Macedo IS,Lima MVA,Souza JS,Rochael NC,Caldas PN,Barbosa HS,Lara FA,Saraiva EM,Mariante RM
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunocytochemistry
Thu Oct 22 00:00:00 EDT 2020
Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis.
JCI insight
Tian Y,Qu S,Alam HB,Williams AM,Wu Z,Deng Q,Pan B,Zhou J,Liu B,Duan X,Ma J,Mondal S,Thompson PR,Stringer KA,Standiford TJ,Li Y
PA5-16672 was used in an ELISA assay to determine the role of PAD2 in the potential therapeutic target of sepsis.
Thu Oct 15 00:00:00 EDT 2020
Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis.
JCI insight
Tian Y,Qu S,Alam HB,Williams AM,Wu Z,Deng Q,Pan B,Zhou J,Liu B,Duan X,Ma J,Mondal S,Thompson PR,Stringer KA,Standiford TJ,Li Y
PA5-16672 was used in an ELISA assay to determine the role of PAD2 in the potential therapeutic target of sepsis.
Thu Oct 15 00:00:00 EDT 2020
SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells.
Cellular and molecular gastroenterology and hepatology
Zhong X,Huang M,Kim HG,Zhang Y,Chowdhury K,Cai W,Saxena R,Schwabe RF,Liangpunsakul S,Dong XC
PA5-16672 was used in Immunohistochemistry to suggest that SIRT6 plays a critical role in the protection against NASH development and it may serve as a potential therapeutic target for NASH.
Fri Jul 09 00:00:00 EDT 2021
SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells.
Cellular and molecular gastroenterology and hepatology
Zhong X,Huang M,Kim HG,Zhang Y,Chowdhury K,Cai W,Saxena R,Schwabe RF,Liangpunsakul S,Dong XC
PA5-16672 was used in Immunohistochemistry to suggest that SIRT6 plays a critical role in the protection against NASH development and it may serve as a potential therapeutic target for NASH.
Fri Jul 09 00:00:00 EDT 2021
Colchicine reduces lung injury in experimental acute respiratory distress syndrome.
PloS one
Dupuis J,Sirois MG,Rhéaume E,Nguyen QT,Clavet-Lanthier MÉ,Brand G,Mihalache-Avram T,Théberge-Julien G,Charpentier D,Rhainds D,Neagoe PE,Tardif JC
PA5-16672 was used in Immunohistochemistry to supports the clinical development of colchicine for the prevention of ARDS in conditions causing ALI.
Fri Jan 15 00:00:00 EST 2021
Colchicine reduces lung injury in experimental acute respiratory distress syndrome.
PloS one
Dupuis J,Sirois MG,Rhéaume E,Nguyen QT,Clavet-Lanthier MÉ,Brand G,Mihalache-Avram T,Théberge-Julien G,Charpentier D,Rhainds D,Neagoe PE,Tardif JC
PA5-16672 was used in Immunohistochemistry to supports the clinical development of colchicine for the prevention of ARDS in conditions causing ALI.
Fri Jan 15 00:00:00 EST 2021
Neutrophil extracellular traps promote scar formation in post-epidural fibrosis.
NPJ Regenerative medicine
Jin Z,Sun J,Song Z,Chen K,Nicolas YSM,Kc R,Ma Q,Liu J,Zhang M
PA5-16672 was used in an ELISA assay to shed light on the roles and mechanisms of NETs in the scar formation post spine operation.
Fri Oct 30 00:00:00 EDT 2020
Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury.
Science advances
Vaibhav K,Braun M,Alverson K,Khodadadi H,Kutiyanawalla A,Ward A,Banerjee C,Sparks T,Malik A,Rashid MH,Khan MB,Waters MF,Hess DC,Arbab AS,Vender JR,Hoda N,Baban B,Dhandapani KM
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury.
Science advances
Vaibhav K,Braun M,Alverson K,Khodadadi H,Kutiyanawalla A,Ward A,Banerjee C,Sparks T,Malik A,Rashid MH,Khan MB,Waters MF,Hess DC,Arbab AS,Vender JR,Hoda N,Baban B,Dhandapani KM
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome.
Mucosal immunology
Liu G,Mateer SW,Hsu A,Goggins BJ,Tay H,Mathe A,Fan K,Neal R,Bruce J,Burns G,Minahan K,Maltby S,Fricker M,Foster PS,Wark PAB,Hansbro PM,Keely S
PA5-16672 was used in Immunohistochemistry-immunofluorescence to investigate the role of PAFR in pulmonary EIMs of IBD, using dextran sulfate sodium (DSS) and anti-CD40 murine models of colitis.
Mon Jul 01 00:00:00 EDT 2019
Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation.
EMBO molecular medicine
Zhao M,Xiong X,Ren K,Xu B,Cheng M,Sahu C,Wu K,Nie Y,Huang Z,Blumberg RS,Han X,Ruan HB
PA5-16672 was used in Immunohistochemistry-immunofluorescence to reveal that protein O-GlcNAcylation in intestinal epithelial cells controls key regulatory mechanisms to maintain mucosal homeostasis.
Wed Aug 01 00:00:00 EDT 2018
PAD4 Deficiency Leads to Decreased Organ Dysfunction and Improved Survival in a Dual Insult Model of Hemorrhagic Shock and Sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Biron BM,Chung CS,Chen Y,Wilson Z,Fallon EA,Reichner JS,Ayala A
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Thu Mar 01 00:00:00 EST 2018
MEHP-induced rat testicular inflammation does not exacerbate germ cell apoptosis.
Reproduction (Cambridge, England)
Voss JJLP,Stermer AR,Ghaffari R,Tiwary R,Richburg JH
PA5-16672 was used in Immunohistochemistry-immunofluorescence to test the hypothesis that the infiltrating immune cells contribute to germ cell apoptosis in rats.
Sun Jul 01 00:00:00 EDT 2018
Suppression of LRRC19 promotes cutaneous wound healing in pressure ulcers in mice.
Organogenesis
Sun J,Wang Z,Wang X
PA5-16672 was used in Immunohistochemistry to support that LRRC19 could be a potential therapeutic target for pressure ulcers.
Tue Jan 02 00:00:00 EST 2018
Cholinergic anti-inflammatory pathway inhibits neointimal hyperplasia by suppressing inflammation and oxidative stress.
Redox biology
Li DJ,Fu H,Tong J,Li YH,Qu LF,Wang P,Shen FM
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Tue May 01 00:00:00 EDT 2018
Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice.
Frontiers in physiology
Gao F,Liu X,Shen Z,Jia X,He H,Gao J,Wu J,Jiang C,Zhou H,Wang Y
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Thu Sep 28 00:00:00 EDT 2023
Histochemical characteristics of regressing vessels in the hyaloid vascular system of neonatal mice: Novel implication for vascular atrophy.
Experimental eye research
Kishimoto A,Kimura S,Nio-Kobayashi J,Takahashi-Iwanaga H,Park AM,Iwanaga T
PA5-16672 was used in ELISA, Immunohistochemistry (Paraffin) to reveal the specificity of the hyaloid vessels by a systematic immunohistochemical approach for marker substances of myeloid cells and the extracellular matrix (ECM) in neonatal mice.
Sun Jul 01 00:00:00 EDT 2018
Macrophages Regulate Unilateral Ureteral Obstruction-Induced Renal Lymphangiogenesis through C-C Motif Chemokine Receptor 2-Dependent Phosphatidylinositol 3-Kinase-AKT-Mechanistic Target of Rapamycin Signaling and Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor-C Expression.
The American journal of pathology
Guo YC,Zhang M,Wang FX,Pei GC,Sun F,Zhang Y,He X,Wang Y,Song J,Zhu FM,Pandupuspitasari NS,Liu J,Huang K,Yang P,Xiong F,Zhang S,Yu Q,Yao Y,Wang CY
PA5-16672 was used in Immunohistochemistry to demonstrate that macrophages can regulate unilateral ureteral obstruction-induced renal lymphangiogenesis by expressing high levels of vascular endothelial growth factor by C-C motif chemokine receptor 2-mediated signalling.
Tue Aug 01 00:00:00 EDT 2017
Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice.
Heliyon
Kongphat W,Pudgerd A,Sridurongrit S
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunohistochemistry
Mon May 01 00:00:00 EDT 2017
Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development.
Cancer discovery
Dimitrova N,Gocheva V,Bhutkar A,Resnick R,Jong RM,Miller KM,Bendor J,Jacks T
PA5-16672 was used in immunohistochemistry - paraffin section to determine stromal miR-143/145 microRNAs promote tumorigenesis
Mon Feb 01 00:00:00 EST 2016
Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer.
Cancer immunology research
Peiffer DS,Wang LS,Zimmerman NP,Ransom BW,Carmella SG,Kuo CT,Chen JH,Oshima K,Huang YW,Hecht SS,Stoner GD
PA5-16672 was used in western blot to study how freeze-dried black raspberries inhibit N-nitrosomethylbenzylamine-induced cancer in rats
Fri Jan 01 00:00:00 EST 2016
Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation.
International journal of cancer
Allaire JM,Roy SA,Ouellet C,Lemieux É,Jones C,Paquet M,Boudreau F,Perreault N
PA5-16672 was used in immunohistochemistry - paraffin section to determine how Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from initiation of polyposis
Wed Jun 01 00:00:00 EDT 2016
Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice.
Arthritis research & therapy
Akashi K,Saegusa J,Sendo S,Nishimura K,Okano T,Yagi K,Yanagisawa M,Emoto N,Morinobu A
PA5-16672 was used in immunohistochemistry - paraffin section to study attenuation of bleomycin-induced skin scelerosis in mice through knockout of endothelin type B receptor signaling
Sat May 21 00:00:00 EDT 2016
Increase of T and B cells and altered BACH2 expression patterns in bone marrow trephines of imatinib-treated patients with chronic myelogenous leukaemia.
Oncology letters
Von Laffert M,Hänel M,Dietel M,Anagnostopoulos I,Jöhrens K
PA5-16672 was used in immunohistochemistry - paraffin section to examine the effects of imatinib on T and B cells in patients with chronic myelogenous leukemia
Sat Oct 01 00:00:00 EDT 2016
Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection.
PLoS pathogens
Lin AE,Beasley FC,Olson J,Keller N,Shalwitz RA,Hannan TJ,Hultgren SJ,Nizet V
PA5-16672 was used in immunohistochemistry to analyze an innate defense against uropathogenic Escherichia coli infection and the role of hypoxia inducible factor-1alpha (HIF-1alpha)
Wed Apr 01 00:00:00 EDT 2015
Genetic deletion of the prostaglandin E2 E prostanoid receptor subtype 3 improves anatomical and functional outcomes after intracerebral hemorrhage.
The European journal of neuroscience
Leclerc JL,Lampert AS,Diller MA,Doré S
PA5-16672 was used in immunohistochemistry - paraffin section to study the contribution of PGE2 -EP3 signaling in modulating anatomical outcomes and functional recovery following intracerebral hemorrhage
Fri May 01 00:00:00 EDT 2015
CFTR-regulated MAPK/NF-κB signaling in pulmonary inflammation in thermal inhalation injury.
Scientific reports
Dong ZW,Chen J,Ruan YC,Zhou T,Chen Y,Chen Y,Tsang LL,Chan HC,Peng YZ
PA5-16672 was used in immunohistochemistry - paraffin section to analyze thermal inhalation injury and pulmonary inflammation and the role of CFTR-regulated MAPK/NF-kappa B signaling
Fri Oct 30 00:00:00 EDT 2015
Statins improve the resolution of established murine venous thrombosis: reductions in thrombus burden and vein wall scarring.
PloS one
Kessinger CW,Kim JW,Henke PK,Thompson B,McCarthy JR,Hara T,Sillesen M,Margey RJ,Libby P,Weissleder R,Lin CP,Jaffer FA
PA5-16672 was used in western blot to test the effects of statins in decreasing thrombus burden and decreasing vein wall injury in established murine stasis and non-stasis chemical-induced venous thrombosis
Wed Jan 13 00:00:00 EST 2016
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.
Nucleic acids research
Luebben SW,Kawabata T,Johnson CS,O'Sullivan MG,Shima N
PA5-16672 was used in immunohistochemistry to study the role of impaired progression of the DNA replication fork in the mechanism by which dormant origin loss and FANCC deletion lead to increased genomic instability
Thu May 01 00:00:00 EDT 2014
Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung.
American journal of physiology. Lung cellular and molecular physiology
Murphy SR,Oslund KL,Hyde DM,Miller LA,Van Winkle LS,Schelegle ES
PA5-16672 was used in immunohistochemistry - paraffin section to assess the postnatal developing lung, neurokinin-1 receptor pathway, and ozone-induced airway epithelial cell death
Mon Sep 15 00:00:00 EDT 2014
Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats.
American journal of physiology. Lung cellular and molecular physiology
Wagenaar GT,Sengers RM,Laghmani el H,Chen X,Lindeboom MP,Roks AJ,Folkerts G,Walther FJ
PA5-16672 was used in immunohistochemistry - paraffin section to study the attenuation of hyperoxia-induced lung and heart injury at a low dose in newborn rats by angiotensin II type 2 receptor ligand PD123319
Fri Aug 01 00:00:00 EDT 2014
Glycyrrhizin inhibits the inflammatory response in mouse mammary epithelial cells and a mouse mastitis model.
The FEBS journal
Fu Y,Zhou E,Wei Z,Liang D,Wang W,Wang T,Guo M,Zhang N,Yang Z
PA5-16672 was used in immunohistochemistry to study the molecular mechanisms underlying the anti-inflammatory actions of glycyrrhizin in murine mammary cells and in vivo in a murine mastitis model
Sun Jun 01 00:00:00 EDT 2014
Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.
Journal of cellular and molecular medicine
Projahn D,Simsekyilmaz S,Singh S,Kanzler I,Kramp BK,Langer M,Burlacu A,Bernhagen J,Klee D,Zernecke A,Hackeng TM,Groll J,Weber C,Liehn EA,Koenen RR
PA5-16672 was used in immunohistochemistry to optimize chemokine delivery in order to treat myocardial infarction
Thu May 01 00:00:00 EDT 2014
Improving effect of Sivelestat on lipopolysaccharide-induced lung injury in rats.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Yuan Q,Jiang YW,Fang QH
PA5-16672 was used in immunohistochemistry to study the protective effect of the neutrophil elastase inhibitor Sivelestat against LPS-induced rat lung injury
Mon Sep 01 00:00:00 EDT 2014
Overexpression of GATA-3 in T cells accelerates dextran sulfate sodium-induced colitis.
Experimental animals
Okamura M,Yoh K,Ojima M,Morito N,Takahashi S
PA5-16672 was used in immunohistochemistry to study the increased severity of dextran sulfate-induced colitis in mice whose T-cells transgenically overexpress GATA-3
Wed Oct 22 00:00:00 EDT 2014
Effects of 28Si ions, 56Fe ions, and protons on the induction of murine acute myeloid leukemia and hepatocellular carcinoma.
PloS one
Weil MM,Ray FA,Genik PC,Yu Y,McCarthy M,Fallgren CM,Ullrich RL
PA5-16672 was used in immunohistochemistry to analyze effects of 56Fe ions, protons, and 28Si ions on induction of murine hepatocellular carcinoma and acute myeloid leukemia
Thu Nov 12 00:00:00 EST 2015
Xist RNA is a potent suppressor of hematologic cancer in mice.
Cell
Yildirim E,Kirby JE,Brown DE,Mercier FE,Sadreyev RI,Scadden DT,Lee JT
PA5-16672 was used in immunohistochemistry to study the role of Xist RNA in suppressing the development of hematological cancers using mice deleted for Xist in the blood compartment
Thu Feb 14 00:00:00 EST 2013
Prevention of hyperoxia-mediated pulmonary inflammation in neonatal rats by caffeine.
The European respiratory journal
Weichelt U,Cay R,Schmitz T,Strauss E,Sifringer M,Bührer C,Endesfelder S
PA5-16672 was used in immunohistochemistry to study the ability of caffeine to protect against pulmonary inflammation caused by hyperoxia in neonatal rats
Mon Apr 01 00:00:00 EDT 2013
Layer V cortical neurons require microglial support for survival during postnatal development.
Nature neuroscience
Ueno M,Fujita Y,Tanaka T,Nakamura Y,Kikuta J,Ishii M,Yamashita T
PA5-16672 was used in immunohistochemistry to study the role of microglial cells in the post-natal development of layer V cortical neurons
Wed May 01 00:00:00 EDT 2013
Myeloperoxidase induces the priming of platelets.
Free radical biology & medicine
Kolarova H,Klinke A,Kremserova S,Adam M,Pekarova M,Baldus S,Eiserich JP,Kubala L
PA5-16672 was used in immunocytochemistry to investigate the role of myeloperoxidase in the function of platelets
Thu Aug 01 00:00:00 EDT 2013
Ambrisentan reduces pulmonary arterial hypertension but does not stimulate alveolar and vascular development in neonatal rats with hyperoxic lung injury.
American journal of physiology. Lung cellular and molecular physiology
Wagenaar GT,Laghmani el H,de Visser YP,Sengers RM,Steendijk P,Baelde HJ,Walther FJ
PA5-16672 was used in immunohistochemistry to study the beneficial effects of an endothelin receptor type A antagonist on pulmonary arterial hypertension in a murine model of neonatal chronic lung disease
Fri Feb 15 00:00:00 EST 2013
CXC chemokine KC fails to induce neutrophil infiltration and neoangiogenesis in a mouse model of myocardial infarction.
Journal of molecular and cellular cardiology
Oral H,Kanzler I,Tuchscheerer N,Curaj A,Simsekyilmaz S,Sönmez TT,Radu E,Postea O,Weber C,Schuh A,Liehn EA
PA5-16672 was used in immunohistochemistry to study whether the CXC chemokine KC has any effect on inflammation and wound repair in a murine model of myocardial infarction
Mon Jul 01 00:00:00 EDT 2013
Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.
Cellular signalling
Yang Y,Yang H,Wang Z,Varadaraj K,Kumari SS,Mergler S,Okada Y,Saika S,Kingsley PJ,Marnett LJ,Reinach PS
PA5-16672 was used in immunohistochemistry to study the mechanism by which injury-induced activativation of CB1 receptors leads to downregulation of corneal TRPV1-induced inflammation
Fri Feb 01 00:00:00 EST 2013
Carbohydrate determinants in ferret conjunctiva are affected by infection with influenza H1N1 virus.
Current eye research
Kirkeby S,Martel CJ,Aasted B,Vorum H
PA5-16672 was used in immunoprecipitation to study the effects of influenza H1N1 infection on carbohydrate determinants of the ferret conjunctiva
Tue Oct 01 00:00:00 EDT 2013
The effectiveness of heliox in acute respiratory distress syndrome.
Annals of thoracic medicine
Yilmaz S,Daglioglu K,Yildizdas D,Bayram I,Gumurdulu D,Polat S
PA5-16672 was used in immunohistochemistry to study acute respiratory distress syndrome and the therapeutic efficacy of heliox treatment
Tue Jan 01 00:00:00 EST 2013
Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis.
PloS one
Harmel-Laws E,Mann EA,Cohen MB,Steinbrecher KA
PA5-16672 was used in immunohistochemistry - paraffin section to report the impact of GC-C activity on mucosal immune responses
Mon Aug 18 00:00:00 EDT 2014
Assessment of ultraviolet B-blocking effects of weekly disposable contact lenses on corneal surface in a mouse model.
Molecular vision
Lin DP,Chang HH,Yang LC,Huang TP,Liu HJ,Chang LS,Lin CH,Chen BY
PA5-16672 was used in immunohistochemistry to study the ability of different weekly disposable contact lenses to protect against UVB irradiation using a murine corneal surface model
Tue Sep 24 00:00:00 EDT 2013
Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis.
PloS one
Ghosh S,DeCoffe D,Brown K,Rajendiran E,Estaki M,Dai C,Yip A,Gibson DL
PA5-16672 was used in immunohistochemistry to study the mechanisms underlying the ability of fish oil to protect against omega-6 PUFA-induced colitis but to increase the susceptibility to sepsis
Mon Dec 02 00:00:00 EST 2013
Microbial symbionts accelerate wound healing via the neuropeptide hormone oxytocin.
PloS one
Poutahidis T,Kearney SM,Levkovich T,Qi P,Varian BJ,Lakritz JR,Ibrahim YM,Chatzigiagkos A,Alm EJ,Erdman SE
PA5-16672 was used in immunohistochemistry to study the role of oxytocin upregulatin in the mechanism by which symbiotic gut bacteria accelerate mammalian wound healing
Thu Aug 07 00:00:00 EDT 2014
Demyelinating diseases: myeloperoxidase as an imaging biomarker and therapeutic target.
Radiology
Forghani R,Wojtkiewicz GR,Zhang Y,Seeburg D,Bautz BR,Pulli B,Milewski AR,Atkinson WL,Iwamoto Y,Zhang ER,Etzrodt M,Rodriguez E,Robbins CS,Swirski FK,Weissleder R,Chen JW
PA5-16672 was used in immunohistochemistry to study the value of myeloperoxidase as a disease biomarker and therapeutic target in demyelinating diseases using a murine model
Tue May 01 00:00:00 EDT 2012
Vasculitis: molecular imaging by targeting the inflammatory enzyme myeloperoxidase.
Radiology
Su HS,Nahrendorf M,Panizzi P,Breckwoldt MO,Rodriguez E,Iwamoto Y,Aikawa E,Weissleder R,Chen JW
PA5-16672 was used in immunohistochemistry to study the utility of molecular imaging of myeloperoxidase to non-invasively detect vasculitis-associated inflammation
Sun Jan 01 00:00:00 EST 2012
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.
The Journal of allergy and clinical immunology
Choy DF,Hsu DK,Seshasayee D,Fung MA,Modrusan Z,Martin F,Liu FT,Arron JR
PA5-16672 was used in immunohistochemistry to perform a comparative study of atopic dermatitis and psoriasis at the level of the transcriptome and to examine the involvement of neutrophilic inflammation
Sat Dec 01 00:00:00 EST 2012
Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation.
Proceedings of the National Academy of Sciences of the United States of America
Qin H,Yeh WI,De Sarno P,Holdbrooks AT,Liu Y,Muldowney MT,Reynolds SL,Yanagisawa LL,Fox TH,Park K,Harrington LE,Raman C,Benveniste EN
PA5-16672 was used in immunohistochemistry to study the modulation of neuroinflammation by myeloid cell SOCS3 and STAT3
Tue Mar 27 00:00:00 EDT 2012
Interleukin-17A is present in neutrophils in endometrioma and stimulates the secretion of growth-regulated oncogene-α (Gro-α) from endometrioma stromal cells.
Fertility and sterility
Takamura M,Osuga Y,Izumi G,Yoshino O,Koga K,Saito A,Hirata T,Hirota Y,Harada M,Hasegawa A,Taketani Y
PA5-16672 was used in immunocytochemistry to study the ability of endometrial neutrophil IL-17A to stimulate endometrial stromal cells to secrete Gro-alpha
Thu Nov 01 00:00:00 EDT 2012
MyD88 signaling promotes both mucosal homeostatic and fibrotic responses during Salmonella-induced colitis.
American journal of physiology. Gastrointestinal and liver physiology
Månsson LE,Montero M,Zarepour M,Bergstrom KS,Ma C,Huang T,Man C,Grassl GA,Vallance BA
PA5-16672 was used in immunohistochemistry to study the role of MyD88 signaling in the response to Salmonella-induced colitis
Wed Aug 01 00:00:00 EDT 2012
Myeloperoxidase inhibition ameliorates multiple system atrophy-like degeneration in a transgenic mouse model.
Neurotoxicity research
Stefanova N,Georgievska B,Eriksson H,Poewe W,Wenning GK
PA5-16672 was used in immunohistochemistry to study the effect of myeloperoxidase inhibition in a murine transgenic model of multiple system atrophy-like degeneration
Tue May 01 00:00:00 EDT 2012
Immunohistochemical analysis on cyclooxygenase-2 for wound age determination.
International journal of legal medicine
Ishida Y,Kimura A,Nosaka M,Kuninaka Y,Takayasu T,Eisenmenger W,Kondo T
PA5-16672 was used in immunocytochemistry to study the value of the immunohistochemical expression of COX-2 for determining the age of wounds
Tue May 01 00:00:00 EDT 2012
Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells.
Artificial organs
Bergmeister H,Grasl C,Walter I,Plasenzotti R,Stoiber M,Schreiber C,Losert U,Weigel G,Schima H
PA5-16672 was used in immunohistochemistry to study the performance of small diameter microspun vascular grafts made of polyurethane in a rat model
Sun Jan 01 00:00:00 EST 2012
Ferulic Acid, an Angelica sinensis-Derived Polyphenol, Slows the Progression of Membranous Nephropathy in a Mouse Model.
Evidence-based complementary and alternative medicine : eCAM
Cheng CW,Chang WL,Chang LC,Wu CC,Lin YF,Chen JS
PA5-16672 was used in immunohistochemistry - paraffin section to evaluate the effectiveness of Angelica sinensis and ferulic acid using a mouse model of membranous nephropathy
Thu Aug 23 00:00:00 EDT 2012
Reduction of liver ischemia reperfusion injury by silencing of TNF-α gene with shRNA.
The Journal of surgical research
Hernandez-Alejandro R,Zhang X,Croome KP,Zheng X,Parfitt J,Chen D,Jevnikar A,Wall W,Min WP,Quan D
PA5-16672 was used in immunohistochemistry to study the beneficial effects of shRNA-mediated TNF-alpha knockdown in a murine model of hepatic ischemia-reperfusion injury
Wed Aug 01 00:00:00 EDT 2012
Satratoxin-G from the black mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys.
Toxicologic pathology
Carey SA,Plopper CG,Hyde DM,Islam Z,Pestka JJ,Harkema JR
PA5-16672 was used in immunohistochemistry to study the development of rhinitis and the apoptosis of nasal airway olfactory neurons following exposure of rhesus monkeys to black mold satratoxin-G
Wed Aug 01 00:00:00 EDT 2012
Prevention of hypoglycemia-induced neuronal death by minocycline.
Journal of neuroinflammation
Won SJ,Kim JH,Yoo BH,Sohn M,Kauppinen TM,Park MS,Kwon HJ,Liu J,Suh SW
PA5-16672 was used in immunohistochemistry to study the ability of minocycline to protect against the induction of neuronal cell death by hypoglycemia
Sat Sep 22 00:00:00 EDT 2012
Tumor necrosis factor-α-mediated threonine 435 phosphorylation of p65 nuclear factor-κB subunit in endothelial cells induces vasogenic edema and neutrophil infiltration in the rat piriform cortex following status epilepticus.
Journal of neuroinflammation
Kim JE,Ryu HJ,Choi SY,Kang TC
PA5-16672 was used in immunohistochemistry to study status epilepticus-induced vasogenic edema and the role played by TNF-alpha mediated epithelial cell p65 NFkB phosphorylation
Thu Jan 12 00:00:00 EST 2012
Skin regeneration in adult axolotls: a blueprint for scar-free healing in vertebrates.
PloS one
Seifert AW,Monaghan JR,Voss SR,Maden M
PA5-16672 was used in immunohistochemistry - frozen section to study the wound repair process in adult axolotls
Fri Jul 27 00:00:00 EDT 2012
MMP-8 deficiency increases TLR/RAGE ligands S100A8 and S100A9 and exacerbates lung inflammation during endotoxemia.
PloS one
González-López A,Aguirre A,López-Alonso I,Amado L,Astudillo A,Fernández-García MS,Suárez MF,Batalla-Solís E,Colado E,Albaiceta GM
PA5-16672 was used in immunohistochemistry to study the effects of MMP8 deficiency on TLR/RAGE ligands and lung inflammation during endotoxemia in mice
Tue Nov 27 00:00:00 EST 2012
Protective role of Akt2 in Salmonella enterica serovar typhimurium-induced gastroenterocolitis.
Infection and immunity
Kum WW,Lo BC,Yu HB,Finlay BB
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunofluorescence
Fri Jul 01 00:00:00 EDT 2011
Protective role of Akt2 in Salmonella enterica serovar typhimurium-induced gastroenterocolitis.
Infection and immunity
Kum WW,Lo BC,Yu HB,Finlay BB
Published figure using Myeloperoxidase polyclonal antibody (Product # PA5-16672) in Immunofluorescence
Fri Jul 01 00:00:00 EDT 2011
17β-estradiol and tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in Helicobacter pylori-infected INS-GAS male mice.
Cancer prevention research (Philadelphia, Pa.)
Sheh A,Ge Z,Parry NM,Muthupalani S,Rager JE,Raczynski AR,Mobley MW,McCabe AF,Fry RC,Wang TC,Fox JG
PA5-16672 was used in immunocytochemistry to assess the effect of E2 and tamoxifen on H. pylori-induced gastric cancer in male and female mice.
Thu Sep 01 00:00:00 EDT 2011
Impaired innate immune response and enhanced pathology during Citrobacter rodentium infection in mice lacking functional P-selectin.
Cellular microbiology
Kum WW,Lo BC,Deng W,Ziltener HJ,Finlay BB
PA5-16672 was used in immunohistochemistry to investigate the influence of P-selectin deletion on innate immunity and Citrobacter infection
Wed Sep 01 00:00:00 EDT 2010
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
PloS one
García-Prieto E,González-López A,Cabrera S,Astudillo A,Gutiérrez-Fernández A,Fanjul-Fernandez M,Batalla-Solís E,Puente XS,Fueyo A,López-Otín C,Albaiceta GM
PA5-16672 was used in immunohistochemistry to study the role of IL-10 in the resistance to bleomycin-induced lung fibrosis in MMP-8-deficient mice
Thu Oct 07 00:00:00 EDT 2010
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.jpg?time=20240507?time=20240507 "Myeloperoxidase Antibody (PA5-16672) in IHC")
