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Invitrogen
Myeloperoxidase Monoclonal Antibody (8E6), FITC
Product Details
GM4192
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
8E6
Immunogen
Human Myeloperoxidase
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Purification
purified
Storage buffer
PBS, pH 7.2, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2536535
Product Specific Information
Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
Analyte Specific Reagent
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Bioinformatics
Protein Aliases: MPO; Myeloperoxidase
Gene Aliases: MPO
UniProt ID: (Human) P05164
Entrez Gene ID: (Human) 4353
response to yeast
hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
aging
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
hydrogen peroxide catabolic process
negative regulation of apoptotic process
negative regulation of growth of symbiont in host
defense response to fungus
oxidation-reduction process
response to gold nanoparticle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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