Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Myeloperoxidase Monoclonal Antibody (9B12G7,4D8B12,9B12D9,9C11A5)
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
Myeloperoxidase Antibody (MA5-15480) in WB
Western blot was performed using Anti-Myeloperoxidase Monoclonal Antibody (Product # MA5-15480) and 87 kDa, 73 kDa and 60 kDa bands corresponding to MPO was observed across cell lines except K-562 and A-431, also it was observed to decrease upon Retinoic Acid treatment. Membrane enriched extracts (30 µg lysate) of HL-60 (Lane 1), HL-60 treated with Retinoic Acid (1uM for 72 Hours) (Lane 2), K-562 (Lane 3) and A-431 (Lane 4) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then tran... View More
Product Details
MA5-15480
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
9B12G7,4D8B12,9B12D9,9C11A5
Immunogen
Purified recombinant fragment of MPO (aa1-193) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_10987565
Product Specific Information
MA5-15480 targets Myeloperoxidase in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15480 immunogen is purified recombinant fragment of MPO (aa1-193) expressed in E. Coli.
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: MPO; Myeloperoxidase
Gene Aliases: MPO
UniProt ID: (Human) P05164
Entrez Gene ID: (Human) 4353
response to yeast
hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
aging
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
hydrogen peroxide catabolic process
negative regulation of apoptotic process
negative regulation of growth of symbiont in host
defense response to fungus
oxidation-reduction process
response to gold nanoparticle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support