Invitrogen

NCEH1 Polyclonal Antibody

4 Published Figures

2 References

View all (7) NCEH1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (4)

NCEH1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

NCEH1 Antibody (PA5-50285) in IHC (P)

Immunohistochemical analysis of NCEH1 in paraffin embedded Human lung cancer tissue using NCEH1 Polyclonal Antibody (Product # PA5-50285) at a 1:80 dilution.

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Product Details

PA5-50285

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:300

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Fusion protein corresponding to residues near the C terminal of human Neutral cholesterol ester hydrolase 1

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2635738

Product Specific Information

The antibody detects endogenous levels of total NCEH1 protein.

Target Information

Neutral cholesterol ester hydrolase 1 (NCEH) also known as arylacetamide deacetylase-like 1 (AADACL1) or KIAA1363 is an enzyme that in humans is encoded by the NCEH1 gene. NCEH is an enzyme located in the endoplasmic reticulum. NCEH hydrolyzes 2-acetyl monoalkylglycerol ether, as part of an enzymatic pathway regulating the levels of platelet activating factor and lysophospholipids that may be involved in cancer development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal of lipid research

Wagner C,Hois V,Eggeling A,Pusch LM,Pajed L,Starlinger P,Claudel T,Trauner M,Zimmermann R,Taschler U,Lass A

PA5-50285 was used in Western Blot to identify KIAA1363 (also annotated as arylacetamide deacetylase 1 or neutral cholesterol ester hydrolase 1) as a novel RE hydrolase.

Tue Mar 01 00:00:00 EST 2022

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal of lipid research

Wagner C,Hois V,Eggeling A,Pusch LM,Pajed L,Starlinger P,Claudel T,Trauner M,Zimmermann R,Taschler U,Lass A

PA5-50285 was used in Western Blot to identify KIAA1363 (also annotated as arylacetamide deacetylase 1 or neutral cholesterol ester hydrolase 1) as a novel RE hydrolase.

Tue Mar 01 00:00:00 EST 2022

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal of lipid research

Wagner C,Hois V,Eggeling A,Pusch LM,Pajed L,Starlinger P,Claudel T,Trauner M,Zimmermann R,Taschler U,Lass A

PA5-50285 was used in Western Blot to identify KIAA1363 (also annotated as arylacetamide deacetylase 1 or neutral cholesterol ester hydrolase 1) as a novel RE hydrolase.

Tue Mar 01 00:00:00 EST 2022

Retinoic acid receptor-related orphan receptor α reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophages.

BMC molecular and cell biology

Matsuoka H,Tokunaga R,Katayama M,Hosoda Y,Miya K,Sumi K,Ohishi A,Kamishikiryo J,Shima A,Michihara A

PA5-50285 was used in Western Blotting to study the mechanisms regulating NCHE1 expression within macrophages, with a focus of RORa inhibition using RORa-deficient mice.

Wed Apr 22 00:00:00 EDT 2020

Retinoic acid receptor-related orphan receptor α reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophages.

BMC molecular and cell biology

Matsuoka H,Tokunaga R,Katayama M,Hosoda Y,Miya K,Sumi K,Ohishi A,Kamishikiryo J,Shima A,Michihara A

PA5-50285 was used in Western Blotting to study the mechanisms regulating NCHE1 expression within macrophages, with a focus of RORa inhibition using RORa-deficient mice.

Wed Apr 22 00:00:00 EDT 2020

Bioinformatics

Protein Aliases: 2-acetyl MAGE hydrolase; Acetylalkylglycerol acetylhydrolase; Arylacetamide deacetylase-like 1; Chlorpyrifos oxon-binding protein; CPO-BP; NCEH; Neutral cholesterol ester hydrolase 1

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Gene Aliases: AADACL1; B230106I24Rik; CPO-BP; KIAA1363; NCEH; NCEH1

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UniProt ID: (Human) Q6PIU2, (Mouse) Q8BLF1

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Entrez Gene ID: (Human) 57552, (Mouse) 320024

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Function(s)

Process(es)

xenobiotic metabolic process catabolic process lipid catabolic process protein dephosphorylation lipid metabolic process metabolic process SMAD protein signal transduction

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NCEH1 Polyclonal Antibody

NCEH1 Antibody (PA5-50285) in IHC (P)

Product Details

PA5-50285

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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