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Product Details
27488-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NDNL2 Fusion Protein Ag26663 (1-90 aa encoded by BC053999)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLQKPRNRG RSGGQAERDR DWSHSGNPGA SRAGEDARVL RDGFAEEAPS TSRGPGGSQG SQGPSPQGAR RAQAAPAVGP RSQKQLELKV S (1-90 aa encoded by BC053999)
Target Information
The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Hepatocellular carcinoma-associated protein 4; hepatocellular carcinoma-associated protein HCA4; MAGE-G1 antigen; magg1; melanoma antigen, family G, 1; Melanoma-associated antigen G1; necdin-like 2; necdin-like 2, SMC5-SMC6 complex component; necdin-like gene 2; Necdin-like protein 2; Non-SMC element 3 homolog; Non-structural maintenance of chromosomes element 3 homolog
Gene Aliases: HCA4; MAGEG1; MAGEL3; NDNL2; NSE3; NSMCE3
UniProt ID: (Human) Q96MG7
Entrez Gene ID: (Human) 56160
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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