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NDUFS3 Antibody (MA5-51449) in IHC (P)
Immunohistochemistry analysis of NDUFS3 in paraffin-embedded human tonsil. Samples were incubated with NDUFS3 Recombinant monoclonal antibody (Product # MA5-51449) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
MA5-51449
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2B2P5
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 37-264 of human NDUFS3 (NP_004542.1).
Conjugate
Form
Liquid
Concentration
0.102 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_3093806
Product Specific Information
Immunogen sequence: ESAGADTRPT VRPRNDVAHK QLSAFGEYVA EILPKYVQQV QVSCFNELEV CIHPDGVIPV LTFLRDHTNA QFKSLVDLTA VDVPTRQNRF EIVYNLLSLR FNSRIRVKTY TDELTPIESA VSVFKAANWY EREIWDMFGV FFANHPDLRR ILTDYGFEGH PFRKDFPLSG YVELRYDDEV KRVVAEPVEL AQEFRKFDLN SPWEAFPVYR QPPESLKLEA GDKKPDAK
Target Information
This gene encodes one of the iron-sulfur protein components of mitochondrial NADH:ubiquinone oxidoreductase. Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-30kD; complex I 30kDa subunit; Complex I-30kD; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit
Gene Aliases: 0610010M09Rik; CI-30; CI-30kD; NDUFS3
UniProt ID: (Human) O75489, (Mouse) Q9DCT2
Entrez Gene ID: (Human) 4722, (Mouse) 68349, (Rat) 295923
mitochondrial electron transport, NADH to ubiquinone
substantia nigra development
negative regulation of cell growth
mitochondrial respiratory chain complex I assembly
reactive oxygen species metabolic process
negative regulation of intrinsic apoptotic signaling pathway
transport
oxidation-reduction process
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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