Product References
The miR-143/145 cluster induced by TGF-β1 suppresses Wilms' tumor 1 expression in cultured human podocytes.
American journal of physiology. Renal physiology
Tabei A,Sakairi T,Hamatani H,Ohishi Y,Watanabe M,Nakasatomi M,Ikeuchi H,Kaneko Y,Kopp JB,Hiromura K
Sat Jul 01 00:00:00 EDT 2023
Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang P,Zhu G,Wu Q,Shen L,Liu D,Wang Z,Wang W,Ren Z,Jia Y,Liu M,Xue Y,Ji D,Hu Y,Yu Y,Wang X
Sat Apr 01 00:00:00 EDT 2023
Genetic analysis of periventricular nodular heterotopia 7 caused by a novel NEDD4L missense mutation: Case and literature summary.
Molecular genetics & genomic medicine
Liu J,Hu J,Duan Y,Qin R,Guo C,Zhou H,Liu H,Liu C
Sat Jul 01 00:00:00 EDT 2023
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Cellular and molecular gastroenterology and hepatology
Yuan J,Lv T,Yang J,Wu Z,Yan L,Yang J,Shi Y,Jiang L
Thu Jan 26 00:00:00 EST 2023
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Theranostics
Guo Q,Xin M,Lu Q,Feng D,Yang V,Peng LF,Whelan KA,Hu W,Wu S,Yang X,Wang H,Rothberg BS,Gamero AM,Gerhard GS,Gao B,Yang L
Wed May 10 00:00:00 EDT 2023
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Theranostics
Guo Q,Xin M,Lu Q,Feng D,Yang V,Peng LF,Whelan KA,Hu W,Wu S,Yang X,Wang H,Rothberg BS,Gamero AM,Gerhard GS,Gao B,Yang L
Wed May 10 00:00:00 EDT 2023
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
Archives of biochemistry and biophysics
Liang X,Liu X,Li W,Zhang L,Zhang B,Lai G,Zhao Y
Sat Jul 01 00:00:00 EDT 2023
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
Archives of biochemistry and biophysics
Liang X,Liu X,Li W,Zhang L,Zhang B,Lai G,Zhao Y
Sat Jul 01 00:00:00 EDT 2023
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
Archives of biochemistry and biophysics
Liang X,Liu X,Li W,Zhang L,Zhang B,Lai G,Zhao Y
Sat Jul 01 00:00:00 EDT 2023
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
Archives of biochemistry and biophysics
Liang X,Liu X,Li W,Zhang L,Zhang B,Lai G,Zhao Y
Sat Jul 01 00:00:00 EDT 2023
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Cancer communications (London, England)
Guo Y,Cui Y,Li Y,Jin X,Wang D,Lei M,Chen F,Liu Y,Xu J,Yao G,Zeng G,Chen X
Mon May 01 00:00:00 EDT 2023
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Cancer communications (London, England)
Guo Y,Cui Y,Li Y,Jin X,Wang D,Lei M,Chen F,Liu Y,Xu J,Yao G,Zeng G,Chen X
Mon May 01 00:00:00 EDT 2023
Pharmacological suppression of Nedd4-2 rescues the reduction of Kv11.1 channels in pathological cardiac hypertrophy.
Frontiers in pharmacology
Zhang H,Fu T,Sun J,Zou S,Qiu S,Zhang J,Su S,Shi C,Li DP,Xu Y
Wed Sep 07 00:00:00 EDT 2022
TH5487, a small molecule inhibitor of OGG1, attenuates pulmonary fibrosis by NEDD4L-mediated OGG1 degradation.
Chemico-biological interactions
Ling H,Song C,Fang Y,Yin Y,Wu Z,Wang Y,Xu Z,Gao S,Li A,Liu G
Mon Aug 01 00:00:00 EDT 2022
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Journal of oncology
Nie XH,Qiu S,Xing Y,Xu J,Lu B,Zhao SF,Li YT,Su ZZ
Wed Jan 11 00:00:00 EST 2023
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Journal of oncology
Nie XH,Qiu S,Xing Y,Xu J,Lu B,Zhao SF,Li YT,Su ZZ
Wed Jan 11 00:00:00 EST 2023
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Journal of oncology
Nie XH,Qiu S,Xing Y,Xu J,Lu B,Zhao SF,Li YT,Su ZZ
Wed Jan 11 00:00:00 EST 2023
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Frontiers in molecular neuroscience
Liu X,Zhang L,Zhang H,Liang X,Zhang B,Tu J,Zhao Y
Sat Jul 16 00:00:00 EDT 2022
Targeted Degradation of 53BP1 Using Ubiquitin Variant Induced Proximity.
Biomolecules
Aminu B,Fux J,Mallette E,Petersen N,Zhang W
Tue Mar 22 00:00:00 EDT 2022
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Cell death & disease
Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J
Thu Aug 18 00:00:00 EDT 2022
PTENα is responsible for protection of brain against oxidative stress during aging.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang P,Li R,Yuan Y,Zhu M,Liu Y,Jin Y,Yin Y
Fri Oct 01 00:00:00 EDT 2021
PTENα is responsible for protection of brain against oxidative stress during aging.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang P,Li R,Yuan Y,Zhu M,Liu Y,Jin Y,Yin Y
Fri Oct 01 00:00:00 EDT 2021
Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage.
Cell death and differentiation
Dai C,Wu B,Chen Y,Li X,Bai Y,Du Y,Pang Y,Wang YT,Dong Z
Sun Aug 01 00:00:00 EDT 2021
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Pharmacological research
Huo L,Gao Y,Zhang D,Wang S,Han Y,Men H,Yang Z,Qin X,Wang R,Kong D,Bai H,Zhang H,Zhang W,Jia Z
Mon Feb 01 00:00:00 EST 2021
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Pharmacological research
Huo L,Gao Y,Zhang D,Wang S,Han Y,Men H,Yang Z,Qin X,Wang R,Kong D,Bai H,Zhang H,Zhang W,Jia Z
Mon Feb 01 00:00:00 EST 2021
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Pharmacological research
Huo L,Gao Y,Zhang D,Wang S,Han Y,Men H,Yang Z,Qin X,Wang R,Kong D,Bai H,Zhang H,Zhang W,Jia Z
Mon Feb 01 00:00:00 EST 2021
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Pharmacological research
Huo L,Gao Y,Zhang D,Wang S,Han Y,Men H,Yang Z,Qin X,Wang R,Kong D,Bai H,Zhang H,Zhang W,Jia Z
Mon Feb 01 00:00:00 EST 2021
Exosomes Derived From Macrophages Enhance Aerobic Glycolysis and Chemoresistance in Lung Cancer by Stabilizing c-Myc via the Inhibition of NEDD4L.
Frontiers in cell and developmental biology
Wang H,Wang L,Pan H,Wang Y,Shi M,Yu H,Wang C,Pan X,Chen Z
Tue Mar 23 00:00:00 EDT 2021
JP1 suppresses proliferation and metastasis of melanoma through MEK1/2 mediated NEDD4L-SP1-Integrin αvβ3 signaling.
Theranostics
Cui J,Shu C,Xu J,Chen D,Li J,Ding K,Chen M,Li A,He J,Shu Y,Yang L,Zhang R,Zhou J
Mon May 03 00:00:00 EDT 2021
The correlation between NEDD4L and HIF-1α levels as a gastric cancer prognostic marker.
International journal of medical sciences
Jiang X,Zhang S,Yin Z,Sheng Y,Yan Q,Sun R,Lu M,Zhang Z,Li Y
Mon Mar 23 00:00:00 EDT 2020
The correlation between NEDD4L and HIF-1α levels as a gastric cancer prognostic marker.
International journal of medical sciences
Jiang X,Zhang S,Yin Z,Sheng Y,Yan Q,Sun R,Lu M,Zhang Z,Li Y
Mon Mar 23 00:00:00 EDT 2020
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.
The Journal of experimental medicine
Chen S,Yun F,Yao Y,Cao M,Zhang Y,Wang J,Song X,Qian Y
Mon Nov 05 00:00:00 EST 2018
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.
The Journal of experimental medicine
Chen S,Yun F,Yao Y,Cao M,Zhang Y,Wang J,Song X,Qian Y
Mon Nov 05 00:00:00 EST 2018
Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.
Infection and immunity
Zhu B,Das S,Mitra S,Farris TR,McBride JW
Fri Sep 01 00:00:00 EDT 2017
Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.
Infection and immunity
Zhu B,Das S,Mitra S,Farris TR,McBride JW
Fri Sep 01 00:00:00 EDT 2017
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Molecular medicine reports
Zhao J,Zhang B,Lai G,Xu R,Chu G,Zhao Y
Fri Dec 01 00:00:00 EST 2017
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Molecular medicine reports
Zhao J,Zhang B,Lai G,Xu R,Chu G,Zhao Y
Fri Dec 01 00:00:00 EST 2017
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Molecular medicine reports
Zhao J,Zhang B,Lai G,Xu R,Chu G,Zhao Y
Fri Dec 01 00:00:00 EST 2017
Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Nature genetics
Broix L,Jagline H,Ivanova E,Schmucker S,Drouot N,Clayton-Smith J,Pagnamenta AT,Metcalfe KA,Isidor B,Louvier UW,Poduri A,Taylor JC,Tilly P,Poirier K,Saillour Y,Lebrun N,Stemmelen T,Rudolf G,Muraca G,Saintpierre B,Elmorjani A,Moïse M,Weirauch NB,Guerrini R,Boland A,Olaso R,Masson C,Tripathy R,Keays D,Beldjord C,Nguyen L,Godin J,Kini U,Nischké P,Deleuze JF,Bahi-Buisson N,Sumara I,Hinckelmann MV,Chelly J
Tue Nov 01 00:00:00 EDT 2016
Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Nature genetics
Broix L,Jagline H,Ivanova E,Schmucker S,Drouot N,Clayton-Smith J,Pagnamenta AT,Metcalfe KA,Isidor B,Louvier UW,Poduri A,Taylor JC,Tilly P,Poirier K,Saillour Y,Lebrun N,Stemmelen T,Rudolf G,Muraca G,Saintpierre B,Elmorjani A,Moïse M,Weirauch NB,Guerrini R,Boland A,Olaso R,Masson C,Tripathy R,Keays D,Beldjord C,Nguyen L,Godin J,Kini U,Nischké P,Deleuze JF,Bahi-Buisson N,Sumara I,Hinckelmann MV,Chelly J
Tue Nov 01 00:00:00 EDT 2016
Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Nature genetics
Broix L,Jagline H,Ivanova E,Schmucker S,Drouot N,Clayton-Smith J,Pagnamenta AT,Metcalfe KA,Isidor B,Louvier UW,Poduri A,Taylor JC,Tilly P,Poirier K,Saillour Y,Lebrun N,Stemmelen T,Rudolf G,Muraca G,Saintpierre B,Elmorjani A,Moïse M,Weirauch NB,Guerrini R,Boland A,Olaso R,Masson C,Tripathy R,Keays D,Beldjord C,Nguyen L,Godin J,Kini U,Nischké P,Deleuze JF,Bahi-Buisson N,Sumara I,Hinckelmann MV,Chelly J
Tue Nov 01 00:00:00 EDT 2016
Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Nature genetics
Broix L,Jagline H,Ivanova E,Schmucker S,Drouot N,Clayton-Smith J,Pagnamenta AT,Metcalfe KA,Isidor B,Louvier UW,Poduri A,Taylor JC,Tilly P,Poirier K,Saillour Y,Lebrun N,Stemmelen T,Rudolf G,Muraca G,Saintpierre B,Elmorjani A,Moïse M,Weirauch NB,Guerrini R,Boland A,Olaso R,Masson C,Tripathy R,Keays D,Beldjord C,Nguyen L,Godin J,Kini U,Nischké P,Deleuze JF,Bahi-Buisson N,Sumara I,Hinckelmann MV,Chelly J
Tue Nov 01 00:00:00 EDT 2016
Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Nature genetics
Broix L,Jagline H,Ivanova E,Schmucker S,Drouot N,Clayton-Smith J,Pagnamenta AT,Metcalfe KA,Isidor B,Louvier UW,Poduri A,Taylor JC,Tilly P,Poirier K,Saillour Y,Lebrun N,Stemmelen T,Rudolf G,Muraca G,Saintpierre B,Elmorjani A,Moïse M,Weirauch NB,Guerrini R,Boland A,Olaso R,Masson C,Tripathy R,Keays D,Beldjord C,Nguyen L,Godin J,Kini U,Nischké P,Deleuze JF,Bahi-Buisson N,Sumara I,Hinckelmann MV,Chelly J
Tue Nov 01 00:00:00 EDT 2016
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Molecular and cellular biology
Li Z,Li J,Bi P,Lu Y,Burcham G,Elzey BD,Ratliff T,Konieczny SF,Ahmad N,Kuang S,Liu X
Wed Oct 01 00:00:00 EDT 2014
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Molecular and cellular biology
Li Z,Li J,Bi P,Lu Y,Burcham G,Elzey BD,Ratliff T,Konieczny SF,Ahmad N,Kuang S,Liu X
Wed Oct 01 00:00:00 EDT 2014
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Molecular and cellular biology
Li Z,Li J,Bi P,Lu Y,Burcham G,Elzey BD,Ratliff T,Konieczny SF,Ahmad N,Kuang S,Liu X
Wed Oct 01 00:00:00 EDT 2014
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Molecular and cellular biology
Li Z,Li J,Bi P,Lu Y,Burcham G,Elzey BD,Ratliff T,Konieczny SF,Ahmad N,Kuang S,Liu X
Wed Oct 01 00:00:00 EDT 2014
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Molecular and cellular biology
Li Z,Li J,Bi P,Lu Y,Burcham G,Elzey BD,Ratliff T,Konieczny SF,Ahmad N,Kuang S,Liu X
Wed Oct 01 00:00:00 EDT 2014
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Molecular and cellular biology
Li Z,Li J,Bi P,Lu Y,Burcham G,Elzey BD,Ratliff T,Konieczny SF,Ahmad N,Kuang S,Liu X
Wed Oct 01 00:00:00 EDT 2014
Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.
International journal of experimental pathology
Kito Y,Bai J,Goto N,Okubo H,Adachi Y,Nagayama T,Takeuchi T
Sat Feb 01 00:00:00 EST 2014
Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.
International journal of experimental pathology
Kito Y,Bai J,Goto N,Okubo H,Adachi Y,Nagayama T,Takeuchi T
Sat Feb 01 00:00:00 EST 2014
Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.
International journal of experimental pathology
Kito Y,Bai J,Goto N,Okubo H,Adachi Y,Nagayama T,Takeuchi T
Sat Feb 01 00:00:00 EST 2014
Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.
International journal of experimental pathology
Kito Y,Bai J,Goto N,Okubo H,Adachi Y,Nagayama T,Takeuchi T
Sat Feb 01 00:00:00 EST 2014
Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway.
International journal of oncology
Jung S,Li C,Jeong D,Lee S,Ohk J,Park M,Han S,Duan J,Kim C,Yang Y,Kim KI,Lim JS,Kang YS,Lee MS
Fri Nov 01 00:00:00 EDT 2013
Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway.
International journal of oncology
Jung S,Li C,Jeong D,Lee S,Ohk J,Park M,Han S,Duan J,Kim C,Yang Y,Kim KI,Lim JS,Kang YS,Lee MS
Fri Nov 01 00:00:00 EDT 2013
Decreased expression of Nedd4L correlates with poor prognosis in gastric cancer patient.
Medical oncology (Northwood, London, England)
Gao C,Pang L,Ren C,Ma T
Sat Sep 01 00:00:00 EDT 2012
Decreased expression of Nedd4L correlates with poor prognosis in gastric cancer patient.
Medical oncology (Northwood, London, England)
Gao C,Pang L,Ren C,Ma T
Sat Sep 01 00:00:00 EDT 2012
YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.
PloS one
Skouloudaki K,Walz G
Thu Sep 13 00:00:00 EDT 2012
YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.
PloS one
Skouloudaki K,Walz G
Thu Sep 13 00:00:00 EDT 2012
YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.
PloS one
Skouloudaki K,Walz G
Thu Sep 13 00:00:00 EDT 2012
YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.
PloS one
Skouloudaki K,Walz G
Thu Sep 13 00:00:00 EDT 2012
Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer.
International journal of experimental pathology
Takeuchi T,Adachi Y,Nagayama T,Furihata M
Fri Apr 01 00:00:00 EDT 2011
Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer.
International journal of experimental pathology
Takeuchi T,Adachi Y,Nagayama T,Furihata M
Fri Apr 01 00:00:00 EDT 2011
Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer.
International journal of experimental pathology
Takeuchi T,Adachi Y,Nagayama T,Furihata M
Fri Apr 01 00:00:00 EDT 2011
Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer.
International journal of experimental pathology
Takeuchi T,Adachi Y,Nagayama T,Furihata M
Fri Apr 01 00:00:00 EDT 2011