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Search Thermo Fisher Scientific
The MW of this protein is 66 kDa, and this antibody specifically recognizes the 66 kDa protein.
Immunogen sequence: VHYCTLRAE LLMSLHDLDV GEICTVDPCH KFTWCLDACI RERFVDSKRA RELQGFLDGV KKGQEQVLGD LSMILCDPFA INTLALSTVR HLQELVGQET LPRDSPDLLL LLRLLALGQG AWDMIDSQVF KEPKMEVELI TRFLPMLMSF LVDDYTFNVD QKLPAEEKAP VSYPNTLPES FTKFLQEQRM ACEVGLYYVL HITKQRNKNA LLRLLPGLVE TFGDLAFGDI FLHLLTGNLA LLADEFALED FCSSLFDGFF LTASPRKENV HRHALRLLIH LHPRVAPSKL EALQKALEPT GQSGEAVKEL YSQLGEKLEQ LDHRKPSPAQ AAETPALELP LPSVPAPAPL (127-475 aa encoded by BC011892)
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2), either NELFC or NELFD (TH1L), and NELFE (RDBP), a heterodimer of SPT4 (SUPT4H1), to cause transcriptional pausing of RNA polymerase II (Narita et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cofactor of BRCA1; DKFZp586B0519; Negative elongation factor B; negative elongation factor complex member B, Cobra1; negative elongation factor protein B; NELF-B; ortholog of human cofactor of BRCA1 (COBRA1); RP13-122B23.3
Gene Aliases: A730008L03Rik; AB041607; AI663983; COBRA1; KIAA1182; MNCb-5210; NELF-B; NELFB; RGD1307832
UniProt ID: (Human) Q8WX92, (Mouse) Q8C4Y3
Entrez Gene ID: (Human) 25920, (Mouse) 58202, (Rat) 311796
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