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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
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Protein Aliases: breast normal epithelial cell associated serine protease; kallikrein 10; kallikrein 10 protein 1; kallikrein 10 protein 12; kallikrein 10 protein 13; kallikrein 10 protein 2; kallikrein 10 protein 3; kallikrein 10 protein 4; kallikrein 10 protein 5; kallikrein 10 protein 7; kallikrein 10 protein 8; kallikrein 10 protein 9; Kallikrein-10; kallikrein-related peptidase 10; Normal epithelial cell-specific 1; Protease serine-like 1; protease, serine-like, 1
Gene Aliases: 2300002A13Rik; KLK10; NES1; PRSSL1
UniProt ID: (Human) O43240
Entrez Gene ID: (Human) 5655, (Rat) 292850, (Mouse) 69540
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