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Product Details
H00010276-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NET1 (NP_005854.2, 1 a.a. approximately 542 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVAHDETGGL LPIKRTIRVL DVNNQSFREQ EEPSNKRVRP LARVTSLANL ISPVRNGAVR RFGQTIQSFT LRGDHRSPAS AQKFSSRSTV PTPAKRRSSA LWSEMLDITM KESLTTREIR RQEAIYEMSR GEQDLIEDLK LARKAYHDPM LKLSIMSEEE LTHIFGDLDS YIPLHEDLLT RIGEATKPDG TVEQIGHILV SWLPRLNAYR GYCSNQLAAK ALLDQKKQDP RVQDFLQRCL ESPFSRKLDL WSFLDIPRSR LVKYPLLLKE ILKHTPKEHP DVQLLEDAIL IIQGVLSDIN LKKGESECQY YIDKLEYLDE KQRDPRIEAS KVLLCHGELR SKSGHKLYIF LFQDILVLTR PVTRNERHSY QVYRQPIPVQ ELVLEDLQDG DVRMGGSFRG AFSNSEKAKN IFRIRFHDPS PAQSHTLQAN DVFHKQQWFN CIRAAIAPFQ SAGSPPELQG LPELHEECEG NHPSARKLTA QRRASTVSSV TQVEVDENAY RCGSGMQMAE DSKSLKTHQT QPGIRRARDK ALSGGKRKET LV
Target Information
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: guanine nucleotide regulatory protein (oncogene); Neuroepithelial cell-transforming gene 1 protein; neuroepithelioma transforming gene 1; p65 Net1 proto-oncogene protein; Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor (GEF) 8; Rho guanine nucleotide exchange factor 8; RP11-116G8.1; small GTP-binding protein regulator
Gene Aliases: ARHGEF8; NET1; NET1A
UniProt ID: (Human) Q12773
Entrez Gene ID: (Human) 10276
regulation of cell growth
signal transduction
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
myoblast migration
cellular response to hydrogen peroxide
cellular response to ionizing radiation
positive regulation of substrate adhesion-dependent cell spreading
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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