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Product Details
H00063973-M08
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
3D8
Immunogen
NEUROG2 (NP_076924, 74 a.a. approximately 175 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: CRPARLLGLV HDCKRRPSRA RAVSRGAKTA ETVQRIKKTR RLKANNRERN RMHNLNAALD ALREVLPTFP EDAKLTKIET LRFAHNYIWA LTETLRLADH CG
Target Information
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHa8; Class A basic helix-loop-helix protein 8; Neurogenin-2; neurogenin2; NGN-2; Protein atonal homolog 4
Gene Aliases: ATOH4; BHLHA8; Math4A; NEUROG2; ngn-2; NGN2
UniProt ID: (Human) Q9H2A3
Entrez Gene ID: (Human) 63973
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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