Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE SFREQDIYLP IANVARIMKN AIPQTGKIAK DAKECVQECV SEFISFITSE ASERCHQEKR KTINGEDILF AMSTLGFDSY VEPLKLYLQK FREAMKGEKG IGGAVTATDG LSEELTEEAF TNQLPAGLIT TDGQQQNVMV YTTSYQQISG VQQIQFS
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold "handshake" motif in a manner analogous to the histone proteins H2B and H2A, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAAT box DNA-binding protein subunit B; CCAAT-binding transcription factor subunit A; nf-y; NF-YB; Nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta; nuclear transcription factor Y, beta; Transcription factor NF-Y, B subunit
Gene Aliases: CBF-A; CBF-B; HAP3; NF-YB; NFYB
UniProt ID: (Human) P25208
Entrez Gene ID: (Human) 4801
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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