Product References
LOX-1 mediates inflammatory activation of microglial cells through the p38-MAPK/NF-κB pathways under hypoxic-ischemic conditions.
Cell communication and signaling : CCS
Aoki Y,Dai H,Furuta F,Akamatsu T,Oshima T,Takahashi N,Goto YI,Oka A,Itoh M
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Western Blot
Fri Jun 02 00:00:00 EDT 2023
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Arthritis research & therapy
Peng P,Wang D,Xu X,Wang D,Gao B,Wang H,Jia H,Shang Q,Zheng C,Gao C,Mao J,Luo Z,Yang L,Hu X
PA5-16545 was used in Western Blot, Immunohistochemistry to induce intervertebral disc degeneration and found that the Intervertebral disc clock was dampened in degenerated human nucleus pulposus specimens, rat nucleus pulposus tissues, and cells.
Wed Aug 03 00:00:00 EDT 2022
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Arthritis research & therapy
Peng P,Wang D,Xu X,Wang D,Gao B,Wang H,Jia H,Shang Q,Zheng C,Gao C,Mao J,Luo Z,Yang L,Hu X
PA5-16545 was used in Western Blot, Immunohistochemistry to induce intervertebral disc degeneration and found that the Intervertebral disc clock was dampened in degenerated human nucleus pulposus specimens, rat nucleus pulposus tissues, and cells.
Wed Aug 03 00:00:00 EDT 2022
Study on Toll-Like Receptor 2-Mediated Inflammation-Induced Familial Hypertension Combined with Hyperlipemia and Its Mechanism.
Journal of healthcare engineering
Liu J,Li C,Wang Q,Hu H,Li C,Qian J
PA5-16545 was used in Western Blot to investigate the influence of Toll-like receptor 2- (TLR2-) mediated inflammation on the occurrence and development of familial hypertension combined with hyperlipemia and its related mechanism.
Thu Apr 21 00:00:00 EDT 2022
Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1.
Journal of biochemical and molecular toxicology
Abdelrahman RS,Abdelsalam RA,Zaghloul MS
PA5-16545 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate the impact of trimetazidine (a metabolic modulator-antianginal drug), against folic acid-induced acute kidney injury.
Sun May 01 00:00:00 EDT 2022
Kukoamine A inhibits C-C motif chemokine receptor 5 to attenuate lipopolysaccharide-induced lung injury.
Drug development research
Liu X,Wang M,Song Y,Zhang C,Jiang Y,Li W,Xu B,Jiang Z
PA5-16545 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that KuA might improve LPS-induced lung injury by inhibiting CCR5.
Thu Sep 01 00:00:00 EDT 2022
Kukoamine A inhibits C-C motif chemokine receptor 5 to attenuate lipopolysaccharide-induced lung injury.
Drug development research
Liu X,Wang M,Song Y,Zhang C,Jiang Y,Li W,Xu B,Jiang Z
PA5-16545 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that KuA might improve LPS-induced lung injury by inhibiting CCR5.
Thu Sep 01 00:00:00 EDT 2022
Identification of Transcription Factor Binding Sites by Cleavage Under Target and Release Using Nuclease in Zebrafish.
Zebrafish
Barakat R,Campbell CA,Espin-Palazon R
PA5-16545 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, ChIP Assay to provide a detailed workflow for the identification of predicted TF binding sites that can be utilized in any animal species and show a strategy which will expand this invaluable tool to the zebrafish community, improving the epigenetic resolution that can be achieved in this model organism.
Wed Jun 01 00:00:00 EDT 2022
Nucleic acid aptamer controls mycoplasma infection for inhibiting the malignancy of esophageal squamous cell carcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy
Zhang Y,Zhang H,Sun X,Peng T,Xie T,Yuan Y,Guo J,Chen Y,Zhou L,Ling N,Li H,Li L,Zhang L,Li X,Liang L,Liu J,Ye M,Tan W
PA5-16545 was used in Western Blotting to indicate that aptamer ZY3A is a potential candidate for development into a novel molecular tool for treatment of M. hyorhinis infection and a safe first-in-class M. hyorhinis-targeting antitumor agent.
Wed Jun 01 00:00:00 EDT 2022
Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach.
Marine drugs
Kirchhoff KN,Billion A,Voolstra CR,Kremb S,Wilke T,Vilcinskas A
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunocytochemistry
Fri Dec 24 00:00:00 EST 2021
Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach.
Marine drugs
Kirchhoff KN,Billion A,Voolstra CR,Kremb S,Wilke T,Vilcinskas A
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunocytochemistry
Fri Dec 24 00:00:00 EST 2021
Bacterial lipopolysaccharides can initiate regeneration of the Xenopus tadpole tail.
iScience
Bishop TF,Beck CW
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Western Blot
Fri Nov 19 00:00:00 EST 2021
Capsaicin Attenuates Lipopolysaccharide-Induced Inflammation and Barrier Dysfunction in Intestinal Porcine Epithelial Cell Line-J2.
Frontiers in physiology
Zhao X,Dong B,Friesen M,Liu S,Zhu C,Yang C
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Western Blot
Tue Oct 12 00:00:00 EDT 2021
Protective Effects of Bariatric Surgery on Kidney Functions by Inhibiting Oxidative Stress Responses Through Activating PPARα in Rats With Diabetes.
Frontiers in physiology
Jiang HW,Zhou Y,Zhou PY,Zhang TY,Hu JY,Bai XT
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunohistochemistry
Sun Apr 24 00:00:00 EDT 2022
Protective Effects of Bariatric Surgery on Kidney Functions by Inhibiting Oxidative Stress Responses Through Activating PPARα in Rats With Diabetes.
Frontiers in physiology
Jiang HW,Zhou Y,Zhou PY,Zhang TY,Hu JY,Bai XT
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunohistochemistry
Sun Apr 24 00:00:00 EDT 2022
A-kinase-interacting protein 1 promotes EMT and metastasis via PI3K/Akt/IKKβ pathway in cervical cancer.
Cell biochemistry and function
Zhang X,Liu S,Zhu Y
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Western Blot
Sat Aug 01 00:00:00 EDT 2020
Saururus chinensis-controlled allergic pulmonary disease through NF-κB/COX-2 and PGE2 pathways.
PeerJ
Song M,Lee SY,Kim M,Park S,Park J,Kwon Y,Park DH
PA5-16545 was used in Immunohistochemistry-immunofluorescence to report findings on the use of Saururus chinensis as a promising drug candidate against fine dust-induced allergic pulmonary disease.
Fri Oct 09 00:00:00 EDT 2020
Saururus chinensis-controlled allergic pulmonary disease through NF-κB/COX-2 and PGE2 pathways.
PeerJ
Song M,Lee SY,Kim M,Park S,Park J,Kwon Y,Park DH
PA5-16545 was used in Immunohistochemistry-immunofluorescence to report findings on the use of Saururus chinensis as a promising drug candidate against fine dust-induced allergic pulmonary disease.
Fri Oct 09 00:00:00 EDT 2020
Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury.
Stem cell research & therapy
Ullah M,Liu DD,Rai S,Razavi M,Concepcion W,Thakor AS
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Western Blot
Mon Sep 14 00:00:00 EDT 2020
Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury.
Stem cell research & therapy
Ullah M,Liu DD,Rai S,Razavi M,Concepcion W,Thakor AS
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Western Blot
Mon Sep 14 00:00:00 EDT 2020
Anti-inflammatory Effect of Curcuma longa and Allium hookeri Co-treatment via NF-κB and COX-2 Pathways.
Scientific reports
Lee SY,Cho SS,Li Y,Bae CS,Park KM,Park DH
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunofluorescence
Tue Mar 31 00:00:00 EDT 2020
Anti-inflammatory Effect of Curcuma longa and Allium hookeri Co-treatment via NF-κB and COX-2 Pathways.
Scientific reports
Lee SY,Cho SS,Li Y,Bae CS,Park KM,Park DH
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunofluorescence
Tue Mar 31 00:00:00 EDT 2020
Anti-inflammatory Effect of Curcuma longa and Allium hookeri Co-treatment via NF-κB and COX-2 Pathways.
Scientific reports
Lee SY,Cho SS,Li Y,Bae CS,Park KM,Park DH
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunofluorescence
Tue Mar 31 00:00:00 EDT 2020
Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways.
Cancer management and research
El-Agamy DS,El-Harbi KM,Khoshhal S,Ahmed N,Elkablawy MA,Shaaban AA,Abo-Haded HM
PA5-16545 was used in Western Blotting to investigate the impact of pristimerin on doxorubicin-induced cardiotoxic effects.
Wed Mar 30 00:00:00 EDT 2022
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Experimental and therapeutic medicine
Guo G,Tian A,Lan X,Fu C,Yan Z,Wang C
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunocytochemistry
Wed May 01 00:00:00 EDT 2019
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Experimental and therapeutic medicine
Guo G,Tian A,Lan X,Fu C,Yan Z,Wang C
Published figure using NFkB p65 polyclonal antibody (Product # PA5-16545) in Immunocytochemistry
Wed May 01 00:00:00 EDT 2019
Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury.
Biomolecules
Rojas-Morales P,Tapia E,León-Contreras JC,González-Reyes S,Jiménez-Osorio AS,Trujillo J,Pavón N,Granados-Pineda J,Hernández-Pando R,Sánchez-Lozada LG,Osorio-Alonso H,Pedraza-Chaverri J
PA5-16545 was used in Western Blot to investigate the effect of preoperative fasting on rental input and fibrosis development after ischemia-reperfusion injury of the kidney.
Thu Aug 22 00:00:00 EDT 2019
Inhibition of indoleamine 2,3-dioxygenase attenuates endotoxin-mediated tolerance in granulosa cells through kynurenine pathway.
Journal of cellular biochemistry
Dahiya S,Onteru SK,Singh D
PA5-16545 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate the effects of LPS exposure on buffalo granulosa cells.
Mon Jul 01 00:00:00 EDT 2019
Radiation-induced premature cellular senescence involved in glomerular diseases in rats.
Scientific reports
Aratani S,Tagawa M,Nagasaka S,Sakai Y,Shimizu A,Tsuruoka S
PA5-16545 was used in Immunocytochemistry to identify the important role of radiation-induced cellular senescence, mainly derived from glomerular endothelial cells, for the development of glomerular injury.
Wed Nov 14 00:00:00 EST 2018
Polyphenols from Tamarix nilotica: LC⁻ESI-MSn Profiling and In Vivo Antifibrotic Activity.
Molecules (Basel, Switzerland)
Sekkien A,Swilam N,Ebada SS,Esmat A,El-Khatib AH,Linscheid MW,Singab AN
PA5-16545 was used in Immunohistochemistry to analyse the polyphenol profile of the alcohol soluble fraction of aqueous Tamarix nilotica extract.
Mon Jun 11 00:00:00 EDT 2018
Proteome Analysis of Hypoxic Glioblastoma Cells Reveals Sequential Metabolic Adaptation of One-Carbon Metabolic Pathways.
Molecular & cellular proteomics : MCP
Zhang K,Xu P,Sowers JL,Machuca DF,Mirfattah B,Herring J,Tang H,Chen Y,Tian B,Brasier AR,Sowers LC
PA5-16545 was used in Western Blotting to study the dynamic proteome responses of glioblastoma cells exposed to hypoxia via quantification of newly synthesised proteins.
Wed Nov 01 00:00:00 EDT 2017
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Nature immunology
Finkin S,Yuan D,Stein I,Taniguchi K,Weber A,Unger K,Browning JL,Goossens N,Nakagawa S,Gunasekaran G,Schwartz ME,Kobayashi M,Kumada H,Berger M,Pappo O,Rajewsky K,Hoshida Y,Karin M,Heikenwalder M,Ben-Neriah Y,Pikarsky E
PA5-16545 was used in immunohistochemistry - paraffin section to study hepatocellular carcinoma and ectopic lymphoid structures function as microniches for tumor progenitor cells
Tue Dec 01 00:00:00 EST 2015
3,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages.
Chemico-biological interactions
Matsebatlela TM,Anderson AL,Gallicchio VS,Elford H,Rice CD
PA5-16545 was used in western blot to study the role of 3,4-Dihydroxy-benzohydroxamic acid (Didox) in acute inflammation and oxidative stress
Mon May 25 00:00:00 EDT 2015
Salmonella Engages Host MicroRNAs To Modulate SUMOylation: a New Arsenal for Intracellular Survival.
Molecular and cellular biology
Verma S,Mohapatra G,Ahmad SM,Rana S,Jain S,Khalsa JK,Srikanth CV
PA5-16545 was used in western blot to report that Salmonella enterica serovar Typhimurium modulates host SUMOylation.
Tue Sep 01 00:00:00 EDT 2015
Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, promotes TNF-α production via nucleotide-binding oligomerization domain containing 2 (Nod2)-dependent NF-κB activation in RAW264.7 cells.
Molecular immunology
Katsunuma K,Yoshinaga K,Ohira Y,Eta R,Sato T,Horii T,Tanaka T,Takei M,Seto K
PA5-16545 was used in immunocytochemistry to evaluated the effects of Z-100 on NF-kB signaling in the murine macrophage cell line RAW264.7
Sun Mar 01 00:00:00 EST 2015
Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.
PloS one
Kraut B,Maier HJ,Kókai E,Fiedler K,Boettger T,Illing A,Kostin S,Walther P,Braun T,Wirth T
PA5-16545 was used in immunohistochemistry to characterize defects in heart development and embryonic lethality due to cardiac-specific activation of IKK2
Mon Jun 13 00:00:00 EDT 2016
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties.
Cell
Schwitalla S,Fingerle AA,Cammareri P,Nebelsiek T,Göktuna SI,Ziegler PK,Canli O,Heijmans J,Huels DJ,Moreaux G,Rupec RA,Gerhard M,Schmid R,Barker N,Clevers H,Lang R,Neumann J,Kirchner T,Taketo MM,van den Brink GR,Sansom OJ,Arkan MC,Greten FR
PA5-16545 was used in immunohistochemistry to study the role of inflammatory signaling in the dedifferentiation and acquisition of stem-like properties associated with intestinal tumorigenesis
Thu Jan 17 00:00:00 EST 2013
Chemopreventive efficacy of green tea drinking against 1,2-dimethyl hydrazine-induced rat colon carcinogenesis.
Cell biochemistry and function
Sadik NA
PA5-16545 was used in immunohistochemistry to study the ability of drinking green tea to prevent against colon carcinogenesis in a rat model
Mon Apr 01 00:00:00 EDT 2013
Surgical removal of endometrioma decreases the NF-kB1 (p50/105) and NF-kB p65 (Rel A) expression in the eutopic endometrium during the implantation window.
Reproductive sciences (Thousand Oaks, Calif.)
Celik O,Celik E,Turkcuoglu I,Yilmaz E,Ulas M,Simsek Y,Karaer A,Celik N,Aydin NE,Ozerol I,Unlu C
PA5-16545 was used in immunohistochemistry to study endometrial levels of NFkB1 and RelA following surgical endometrioma removal
Mon Jul 01 00:00:00 EDT 2013
Nuclear transcription factor-kappa beta-dependent ultrastructural alterations within the placenta and systemic inflammatory activation in pregnant patients with hemolysis, elevated liver functions and low thrombocyte count (HELLP) syndrome: a case-control study.
Hypertension in pregnancy
Simsek Y,Gul M,Celik O,Aydin NE,Arda Düz S,Celik E,Ozerol E,Özerol IH,Tanbek K
PA5-16545 was used in immunohistochemistry to study the potential role of placental NFkB overexpression in the pathophysiology of HELLP syndrome
Thu Aug 01 00:00:00 EDT 2013
Oral epithelial barrier function and the role of nuclear factor kappa-β pathway in the pathogenesis of aphthous ulceration.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
Günhan Ö,Günal A,Avcı A,Kurgan Ş,Dereci Ö,Kurt B,Celasun B
PA5-16545 was used in immunohistochemistry to study loss of oral epithelial barrier function in the pathogenesis of aphthous ulceration and the involvement of NFkB signaling pathways
Wed Jan 21 00:00:00 EST 2015
Identification of multipath genes differentially expressed in pathway-targeted microarrays in zebrafish infected and surviving spring viremia carp virus (SVCV) suggest preventive drug candidates.
PloS one
Encinas P,Garcia-Valtanen P,Chinchilla B,Gomez-Casado E,Estepa A,Coll J
PA5-16545 was used in immunocytochemistry to use zebrafish to identify factors altered during infection with spring viremia carp virus
Mon Apr 28 00:00:00 EDT 2014
Comparative gene expression profiling identifies common molecular signatures of NF-κB activation in canine and human diffuse large B cell lymphoma (DLBCL).
PloS one
Mudaliar MA,Haggart RD,Miele G,Sellar G,Tan KA,Goodlad JR,Milne E,Vail DM,Kurzman I,Crowther D,Argyle DJ
PA5-16545 was used in western blot to perform a comparative study of the gene expression profiles of canine and human diffuse large B-cell lymphoma with particular reference to the NFkB pathway
Wed Apr 02 00:00:00 EDT 2014
Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation.
Hepatology (Baltimore, Md.)
Sunami Y,Leithäuser F,Gul S,Fiedler K,Güldiken N,Espenlaub S,Holzmann KH,Hipp N,Sindrilaru A,Luedde T,Baumann B,Wissel S,Kreppel F,Schneider M,Scharffetter-Kochanek K,Kochanek S,Strnad P,Wirth T
PA5-16545 was used in immunohistochemistry to study the role of chronic inflammation mediated by macrophages in the development of fibrosis following activation of hepatic IKK/NFkB
Sat Sep 01 00:00:00 EDT 2012
Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model.
Journal of ethnopharmacology
Peng L,Li M,Xu YZ,Zhang GY,Yang C,Zhou YN,Li LJ,Zhang JP
PA5-16545 was used in immunohistochemistry to study the ability of the Chinese herbal remedy Si-Miao-Yong-An to increase atherosclerotic plaque stability
Thu Aug 30 00:00:00 EDT 2012
Calpastatin upregulation in Mycoplasma hyorhinis-infected cells is promoted by the mycoplasma lipoproteins via the NF-κB pathway.
Cellular microbiology
Elkind E,Vaisid T,Kornspan JD,Barnoy S,Rottem S,Kosower NS
PA5-16545 was used in immunocytochemistry and western blot to study the mechanism by which mycoplasma lipoproteins upregulate calpastatin in Mycoplasma hyorhinis-infected cells
Fri Jun 01 00:00:00 EDT 2012
Potential role of p38-mitogene-activated protein kinase and nuclear factor-kappa B expression in testicular dysfunction associated with varicocele: an experimental study.
Andrologia
Simsek A,Ozbek E,Ilbey YO,Cekmen M,Somay A,Tasci AI
PA5-16545 was used in immunohistochemistry to study the roles of p38-MAPK and NFkB in a rat model of testicular dysfunction
Tue May 01 00:00:00 EDT 2012
Extensive fibrin accumulation and accompanying epithelial changes in the pathogenesis of ligneous mucosal disease (ligneous periodontitis).
The American Journal of dermatopathology
Günhan Ö,Avci A,Dereci Ö,Akgün S,Celasun B
PA5-16545 was used in immunohistochemistry to study the pathogenesis of ligneous peridontitis and the role played by fibrin accumulation
Wed Feb 01 00:00:00 EST 2012
Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.
PloS one
Lunova M,Zizer E,Kucukoglu O,Schwarz C,Dillmann WH,Wagner M,Strnad P
PA5-16545 was used in immunohistochemistry and western blot to study the ability of transgenic overexpression of HSP72 to speed recovery in a murine model of pancreatitis
Tue Mar 19 00:00:00 EDT 2013
Expression of nuclear factor kappa B and survivin in psoriasis.
ISRN dermatology
Gunduz K,Temiz P,Gencoglan G,Inanir I,Catalkaya A
PA5-16545 was used in immunohistochemistry to perform a comparative study of NFkB and survivin expression in normal and psoriatic epidermis
Wed Dec 12 00:00:00 EST 2012
Pulmonary cryptosporidiosis: role of COX2 and NF-kB.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Asaad NY,Sadek GS
PA5-16545 was used in immunohistochemistry - paraffin section to test if Cryptosporidium-induced changes in the lungs are mediated through the activation of COX-2 and NF-kB
Sun Oct 01 00:00:00 EDT 2006