Invitrogen

NG2 Monoclonal Antibody (N143.8)

NG2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 3

NG2 Antibody (37-2300) in ICC/IF

Experimental neurology 2008 - Published figure using NG2 monoclonal antibody (Product # 37-2300) in Immunocytochemistry

NG2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

Product Details

37-2300

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

View 1 publication 1 publication

ELISA (ELISA)

Assay-dependent

Immunoprecipitation (IP)

Assay-dependent

Product Specifications

Species Reactivity

Human, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

N143.8

Immunogen

Purified rat NG2 protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533306

Target Information

A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K⁺ Channel Kv1.3.

Frontiers in cellular neuroscience

Liu H,Yang X,Yang J,Yuan Y,Wang Y,Zhang R,Xiong H,Xu Y

37-2300 was used in Immunohistochemistry (PFA fixed) to suggest that IL-17 impairs remyelination and promotes myelin damage by Kv1.3-mediated Ol/myelin injury.

Sat Jul 10 00:00:00 EDT 2021

IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K⁺ Channel Kv1.3.

Frontiers in cellular neuroscience

Liu H,Yang X,Yang J,Yuan Y,Wang Y,Zhang R,Xiong H,Xu Y

37-2300 was used in Immunohistochemistry (PFA fixed) to suggest that IL-17 impairs remyelination and promotes myelin damage by Kv1.3-mediated Ol/myelin injury.

Sat Jul 10 00:00:00 EDT 2021

Preclinical safety of human embryonic stem cell-derived oligodendrocyte progenitors supporting clinical trials in spinal cord injury.

Regenerative medicine

Priest CA,Manley NC,Denham J,Wirth ED,Lebkowski JS

37-2300 was used in flow cytometry to assess the preclinical safety profile of a human embryonic stem cell-derived oligodendrocyte progenitor cell therapy product to treat spinal cord injury

Sun Nov 01 00:00:00 EDT 2015

Preclinical safety of human embryonic stem cell-derived oligodendrocyte progenitors supporting clinical trials in spinal cord injury.

Regenerative medicine

Priest CA,Manley NC,Denham J,Wirth ED,Lebkowski JS

37-2300 was used in flow cytometry to assess the preclinical safety profile of a human embryonic stem cell-derived oligodendrocyte progenitor cell therapy product to treat spinal cord injury

Sun Nov 01 00:00:00 EDT 2015

Early proliferation does not prevent the loss of oligodendrocyte progenitor cells during the chronic phase of secondary degeneration in a CNS white matter tract.

PloS one

Payne SC,Bartlett CA,Savigni DL,Harvey AR,Dunlop SA,Fitzgerald M

Thu Jan 16 00:00:00 EST 2014

Axon growth across a lesion site along a preformed guidance pathway in the brain.

Experimental neurology

Jin Y,Ziemba KS,Smith GM

Tue Apr 01 00:00:00 EDT 2008

Axon growth across a lesion site along a preformed guidance pathway in the brain.

Experimental neurology

Jin Y,Ziemba KS,Smith GM

Tue Apr 01 00:00:00 EDT 2008

Bioinformatics

Protein Aliases: Chondroitin sulfate proteoglycan 4; chondroitin sulfate proteoglycan 4 (melanoma-associated); Chondroitin sulfate proteoglycan NG2; HMW MAA; HSN tumor-specific antigen; MEL CSPG; Melanoma chondroitin sulfate proteoglycan; Melanoma-associated chondroitin sulfate proteoglycan; membrane-spanning proteoglycan NG2

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Gene Aliases: CSPG4; HMW-MAA; MCSP; MCSPG; MEL-CSPG; MSK16; NG2

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UniProt ID: (Human) Q6UVK1, (Rat) Q00657

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Entrez Gene ID: (Human) 1464, (Rat) 81651

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Function(s)

signal transducer activity protein kinase binding collagen binding

Process(es)

activation of MAPK activity angiogenesis transmembrane receptor protein tyrosine kinase signaling pathway cell proliferation glial cell migration cell migration glycosaminoglycan metabolic process chondroitin sulfate biosynthetic process chondroitin sulfate catabolic process dermatan sulfate biosynthetic process intracellular signal transduction tissue remodeling positive regulation of peptidyl-tyrosine phosphorylation inflammatory response signal transduction response to lithium ion negative regulation of neuron projection development neuron remodeling

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NG2 Monoclonal Antibody (N143.8)

NG2 Antibody (37-2300) in ICC/IF

Product Details

37-2300

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

Bioinformatics

Performance Guarantee

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