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Product Details
ABS 039-15-02
Product Specifications
Species Reactivity
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
15
Immunogen
Recombinant rat NGAL precursor with C-terminal His-tag coupled to carrier.
Conjugate
Form
Liquid
Concentration
1.08 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2536219
Product Specific Information
ABS 039-15-02 shows no cross-reaction with human, pig, dog, or mouse NGAL.
Reactivity: ABS 039-15-02 binds free rat NGAL in solution. ABS 039-15-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 039-32-02. Rat NGAL measures 4-400 pg/mL in an optimized assay.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; HGNC:6526; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin-2; Lipocalin2; Neutrophil gelatinase-associated lipocalin; NGAL; OTTHUMP00000022240; p25; RP23-161B9.11; Siderocalin LCN2; uterocalin
Gene Aliases: Lcn2; Sip24
UniProt ID: (Rat) P30152
Entrez Gene ID: (Rat) 170496
ion transport
response to oxidative stress
response to virus
response to bacterium
response to herbicide
response to mycotoxin
positive regulation of gene expression
siderophore transport
positive regulation of cell projection organization
response to nutrient levels
cellular response to nutrient levels
response to drug
innate immune response
iron ion homeostasis
protein homotrimerization
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
extrinsic apoptotic signaling pathway in absence of ligand
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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