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Product Details
14380-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NIT1 Fusion Protein Ag5764 (1-243 aa encoded by BC046149)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLGFITRPP HRFLSLLCPG LRIPQLSVLC AQPRPRAMAI SSSSCELPLV AVCQVTSTPD KQQNFKTCAE LVREAARLGP CLAFLPEAFD FIARDPAETL HLSEPLGGKL LEEYTQLARE CGLWLSLGGF HERGQDWEQT QKIYNCHVLL NSKGAVVATY RKTHLCDVEI PGQGPMCESN STMPGPSLES PVSTPAGKIG LAVCYDMRFP ELSLALAQAG AEILTYPSAF GSITGPAHWE PVSS (1-243 aa encoded by BC046149)
Target Information
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Deaminated glutathione amidase; dGSH amidase; MGC57670; Nitrilase homolog 1
Gene Aliases: NIT1
UniProt ID: (Human) Q86X76
Entrez Gene ID: (Human) 4817
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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