Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MTSFRLALIQ LQISSIKSDN VTRACSFIRE AATQGAKIVS LPECFNSPYG AKYFPEYAEK IPGESTQKLS EVAKECSIYL IGGSIPEEDA GKLYNTCAVF GPDGTLLAKY RKIHLFDIDV PGKITFQESK TLSPGDSFST FDTPYCRVGL GICYDMRFAE LAQIYAQRGC QLLVYPGAFN LTTGPAHWEL LQRSRAVDNQ VYVATASPAR DDKASYVAWG HSTVVNPWGE ALAKAGTEEA IVYSDIDLKK LAEIRQQIPV FRQKRSDLYA VEMKKP
Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 8a; Nit protein 2; nitrilase family, member 2; Nitrilase homolog 2; Omega-amidase NIT2
Gene Aliases: 1190017B19Rik; CUA002; D16Ertd502e; HEL-S-8a; NIT2; RGD1310494
UniProt ID: (Human) Q9NQR4, (Rat) Q497B0, (Mouse) Q9JHW2
Entrez Gene ID: (Human) 56954, (Pig) 100625406, (Rat) 288174, (Mouse) 52633
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