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Bethyl Laboratories
NKG2A Recombinant Rabbit Monoclonal Antibody (BLR290L)
Product Details
A700-290
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
BLR290L
Immunogen
Peptide representing a region between residue 0 and 50 of Human NKG2A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
purified
Storage buffer
BBS, pH 8.2
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-lectin type II protein; CD159 antigen-like family member A; CD159a; killer cell lectin-like receptor subfamily C, member 1; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2-1/B activating NK receptor; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein
Gene Aliases: CD159A; KLRC1; NKG2; NKG2A
UniProt ID: (Human) P26715
Entrez Gene ID: (Human) 3821
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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