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Product Details
BS-2416R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human NKG2C.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-lectin type II protein; CD159 antigen-like family member A; CD159 antigen-like family member C; CD159a; CD159c; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NK cell receptor C; NK cell receptor E; NK cell receptor F; NKG2-1/B activating NK receptor; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
Gene Aliases: CD159A; CD159c; KLRC1; KLRC2; KLRC3; KLRC4; NKG2; NKG2-C; NKG2-E; NKG2-F; NKG2A; NKG2C; NKG2E; NKG2F
UniProt ID: (Human) P26715, (Human) P26717, (Human) Q07444, (Human) O43908
Entrez Gene ID: (Human) 3821, (Human) 3822, (Human) 3823, (Human) 8302
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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