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NMDAR1 Antibody (MA5-50204) in Flow
Flow cytometry analysis overlay peak curve showing SH-SY5Y cells stained with (Product # MA5-50204) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at (1x10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Product Details
MA5-50204
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
24F5
Immunogen
A synthesized peptide derived from Human GRIN1
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3092588
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GluN1; Glun1r; glutamate [NMDA] receptor subunit zeta 1; Glutamate [NMDA] receptor subunit zeta-1; glutamate receptor; Glutamate receptor ionotropic, NMDA 1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; NMDA receptor 1; NMDZ1; NMZ1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; RP11-350O14.1
Gene Aliases: GluN1; GRIN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1
UniProt ID: (Human) Q05586
Entrez Gene ID: (Human) 2902
NMDA glutamate receptor activity
Ras guanyl-nucleotide exchange factor activity
extracellular-glutamate-gated ion channel activity
calcium channel activity
calcium ion binding
protein binding
calmodulin binding
glycine binding
glutamate binding
enzyme binding
voltage-gated cation channel activity
glutamate receptor binding
neurotransmitter binding
protein heterodimerization activity
transmembrane signal receptor
MAPK cascade
conditioned taste aversion
suckling behavior
response to amphetamine
cation transport
cellular calcium ion homeostasis
chemical synaptic transmission
respiratory gaseous exchange
long-term memory
adult locomotory behavior
olfactory learning
visual learning
propylene metabolic process
sensory perception of pain
pons maturation
cerebral cortex development
regulation of ion transmembrane transport
social behavior
ionotropic glutamate receptor signaling pathway
synaptic transmission, glutamatergic
regulation of membrane potential
positive regulation of apoptotic process
response to morphine
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
regulation of respiratory gaseous exchange
response to ethanol
positive regulation of transcription from RNA polymerase II promoter
ephrin receptor signaling pathway
regulation of long-term neuronal synaptic plasticity
rhythmic process
regulation of dendrite morphogenesis
regulation of axonogenesis
protein tetramerization
response to calcium ion
regulation of synapse assembly
calcium ion homeostasis
excitatory postsynaptic potential
prepulse inhibition
male mating behavior
response to fungicide
calcium ion transmembrane transport
cellular response to manganese ion
positive regulation of excitatory postsynaptic potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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