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NME4 Antibody (PA5-78081) in IHC (P)
nm23-H4 antibody detects nm23-H4 protein at cytosol on mouse hind brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse hind brain. Nm23-H4 antibody (Product # PA5-78081) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-78081
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human NME4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2736239
Product Specific Information
Positive Control: human NME4-transfected 293T cells
Predicted Reactivity: Xenopus laevis (80%), Pig (90%), Rhesus Monkey (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NME4 is a protein kinases, which are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: expressed in non-metastatic cells 4, protein; NDK; NDP kinase D; NDP kinase, mitochondrial; NDPKD; nm23-H4; nm23-M4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; Nucleoside diphosphate kinase D; Nucleoside diphosphate kinase, mitochondrial
Gene Aliases: 2610027N22Rik; 2810024O08Rik; 5730493H09Rik; NDPK-D; nm23-H4; NM23-M4; NM23D; NM23H4; Nm23M4; NME4
UniProt ID: (Human) O00746, (Mouse) Q9WV84
Entrez Gene ID: (Human) 4833, (Rat) 685679, (Mouse) 56520
purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
lipid transport
nucleoside metabolic process
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
regulation of apoptotic process
nucleotide metabolic process
phosphorylation
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