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PA1-4329 detects NORE1 from human, mouse and rat samples.
PA1-4329 has been successfully used in Western blot procedures.
The PA1-4329 immunizing peptide corresponds to amino acid residues 313-329 from human NORE1 protein.
Maintain at 4ºc for up to 3 months or at -20ºC for longer periods.
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Maxp1; MGC10823; MGC17344; New ras effector 1; novel Ras effector 1; protein interacting with guanine nucleotide exchange factor; Rap1-binding protein; RAPL; Ras association (RalGDS/AF-6) domain family 5; Ras association (RalGDS/AF-6) domain family member 5; Ras association domain-containing protein 5; Ras effector-like protein; regulator for cell adhesion and polarization enriched in lymphoid tissue; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RP11-343H5.1; tumor; tumor suppressor RASSF3
Gene Aliases: 1300019G20Rik; AU042887; Maxp1; NORE1; NORE1A; NORE1B; RAPL; RASSF3; RASSF5
UniProt ID: (Human) Q8WWW0, (Mouse) Q5EBH1, (Rat) O35141
Entrez Gene ID: (Human) 83593, (Mouse) 54354, (Rat) 54355
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