Product References
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Biological trace element research
Zhang W,Sun J,Liu F,Li S,Wang X,Su L,Liu G
Thu Feb 01 00:00:00 EST 2024
Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke.
Cell death & disease
Zheng H,Guo X,Kang S,Li Z,Tian T,Li J,Wang F,Yu P,Chang S,Chang YZ
Sat Feb 25 00:00:00 EST 2023
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
European journal of pharmacology
Qiao N,An Z,Fu Z,Chen X,Tong Q,Zhang Y,Ren H
Thu Jun 15 00:00:00 EDT 2023
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
European journal of pharmacology
Qiao N,An Z,Fu Z,Chen X,Tong Q,Zhang Y,Ren H
Thu Jun 15 00:00:00 EDT 2023
Therapeutic Hypothermia after Cardiac Arrest Attenuates Hindlimb Paralysis and Damage of Spinal Motor Neurons and Astrocytes through Modulating Nrf2/HO-1 Signaling Pathway in Rats.
Cells
Ahn JH,Lee TK,Kim DW,Shin MC,Cho JH,Lee JC,Tae HJ,Park JH,Hong S,Lee CH,Won MH,Kim YH
Thu Jan 26 00:00:00 EST 2023
Therapeutic Hypothermia after Cardiac Arrest Attenuates Hindlimb Paralysis and Damage of Spinal Motor Neurons and Astrocytes through Modulating Nrf2/HO-1 Signaling Pathway in Rats.
Cells
Ahn JH,Lee TK,Kim DW,Shin MC,Cho JH,Lee JC,Tae HJ,Park JH,Hong S,Lee CH,Won MH,Kim YH
Thu Jan 26 00:00:00 EST 2023
Bifidobacterium animalis A12 and Lactobacillus salivarius M18-6 Alleviate Alcohol Injury by keap1-Nrf2 Pathway and Thioredoxin System.
Foods (Basel, Switzerland)
Zhang Y,Ma J,Jing N,Zhang H,Xie Y,Liu H,Shan X,Ren J,Jin J
Tue Jan 17 00:00:00 EST 2023
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
International immunopharmacology
Chen L,Mao M,Liu D,Liu W,Wang Y,Xie L,Deng Y,Lin Y,Xu Y,Zhong X,Cao W
Wed Mar 01 00:00:00 EST 2023
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Molecular medicine reports
Xiao S,Zhou Y,Gao H,Yang D
Sun Jan 01 00:00:00 EST 2023
Fresh Medium or L-Cystine as an Effective Nrf2 Inducer for Cytoprotection in Cell Culture.
Cells
Dai W,Chen QM
Thu Jan 12 00:00:00 EST 2023
Fresh Medium or L-Cystine as an Effective Nrf2 Inducer for Cytoprotection in Cell Culture.
Cells
Dai W,Chen QM
Thu Jan 12 00:00:00 EST 2023
CircOMA1 modulates cabergoline resistance by downregulating ferroptosis in prolactinoma.
Journal of endocrinological investigation
Wu N,Zhu D,Li J,Li X,Zhu Z,Rao Q,Hu B,Wang H,Zhu Y
Tue Aug 01 00:00:00 EDT 2023
CircOMA1 modulates cabergoline resistance by downregulating ferroptosis in prolactinoma.
Journal of endocrinological investigation
Wu N,Zhu D,Li J,Li X,Zhu Z,Rao Q,Hu B,Wang H,Zhu Y
Tue Aug 01 00:00:00 EDT 2023
Olanzapine-induced nonalcoholic fatty liver disease: The effects of differential food pattern and the involvement of PGRMC1 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhu Z,Cao T,Chen H,Zhang B,Lin C,Cai H
Thu Jun 01 00:00:00 EDT 2023
Piezo1 alleviates acetaminophen-induced acute liver injury by activating Nrf2 and reducing mitochondrial reactive oxygen species.
Biochemical and biophysical research communications
Wang Q,Peng X,Chen Y,Tang X,Qin Y,He M,Chen W,Chen H
Sun Apr 16 00:00:00 EDT 2023
Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation.
Free radical biology & medicine
Zhang B,Hou Q,Zhang X,Ma Y,Yuan J,Li S,Zhao X,Sun L,Wang H,Zheng H
Wed Feb 01 00:00:00 EST 2023
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Frontiers in endocrinology
Zou YY,Tang XB,Chen ZL,Liu B,Zheng L,Song MY,Xiao Q,Zhou ZQ,Peng XY,Tang CF
Fri Jun 09 00:00:00 EDT 2023
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
International journal of molecular sciences
Lai K,Song C,Gao M,Deng Y,Lu Z,Li N,Geng Q
Tue Mar 07 00:00:00 EST 2023
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Bioengineering & translational medicine
Zhu Z,Li X,Wang X,Zuo X,Ma Y,Gao X,Liang Z,Zhang Z,Song Z,Ding T,Ju C,Li P,Li K,Zhang J,Quan H,Wang Z,Hu X
Mon May 01 00:00:00 EDT 2023
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
ACS omega
Feng C,Liu Y,Zhang BY,Zhang H,Shan FY,Li TQ,Zhao ZN,Wang XX,Zhang XY
Tue Jun 13 00:00:00 EDT 2023
Pgp3 protein of Chlamydia trachomatis inhibits apoptosis via HO-1 upregulation mediated by PI3K/Akt activation.
Microbial pathogenesis
Shu M,Bu J,Lei W,Chen L,Zhou Z,Lu C,Chen C,Li Z
Mon May 01 00:00:00 EDT 2023
Wenqingyin suppresses ferroptosis in the pathogenesis of sepsis-induced liver injury by activating the Nrf2-mediated signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xie L,Zhou C,Wu Y,Fu X,Zhang G,Han X,Xie S,Chen G,Xu H,Deng B,Liu B,Zhou Y,Li A
Thu Jun 01 00:00:00 EDT 2023
Wenqingyin suppresses ferroptosis in the pathogenesis of sepsis-induced liver injury by activating the Nrf2-mediated signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xie L,Zhou C,Wu Y,Fu X,Zhang G,Han X,Xie S,Chen G,Xu H,Deng B,Liu B,Zhou Y,Li A
Thu Jun 01 00:00:00 EDT 2023
Wenqingyin suppresses ferroptosis in the pathogenesis of sepsis-induced liver injury by activating the Nrf2-mediated signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xie L,Zhou C,Wu Y,Fu X,Zhang G,Han X,Xie S,Chen G,Xu H,Deng B,Liu B,Zhou Y,Li A
Thu Jun 01 00:00:00 EDT 2023
Wenqingyin suppresses ferroptosis in the pathogenesis of sepsis-induced liver injury by activating the Nrf2-mediated signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xie L,Zhou C,Wu Y,Fu X,Zhang G,Han X,Xie S,Chen G,Xu H,Deng B,Liu B,Zhou Y,Li A
Thu Jun 01 00:00:00 EDT 2023
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Oxidative medicine and cellular longevity
Wan H,Cai Y,Xiao L,Ling Y,Ge L,Mo S,Xie Q,Peng S,Zhou B,Zeng X,Chen X
Tue Jan 23 00:00:00 EST 2024
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Oxidative medicine and cellular longevity
Wan H,Cai Y,Xiao L,Ling Y,Ge L,Mo S,Xie Q,Peng S,Zhou B,Zeng X,Chen X
Tue Jan 23 00:00:00 EST 2024
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Oxidative medicine and cellular longevity
Wan H,Cai Y,Xiao L,Ling Y,Ge L,Mo S,Xie Q,Peng S,Zhou B,Zeng X,Chen X
Tue Jan 23 00:00:00 EST 2024
Buyang Huanwu decoction alleviates oxidative injury of cerebral ischemia-reperfusion through PKCε/Nrf2 signaling pathway.
Journal of ethnopharmacology
Yin M,Liu Z,Wang J,Gao W
Wed Mar 01 00:00:00 EST 2023
Effects of NBP on postoperative cognitive dysfunction in rats via Nrf 2/ARE pathway.
Aging
He J,Gao J,Zhu H,Zhao Y,Zhang X,Wang X,Wan S,Cao H,Zhai L,Wang Y,Wang S
Mon Jan 09 00:00:00 EST 2023
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang C,Lu T,Liu M,Yuan X,Li D,Zhang J,Zhou L,Xu M
Wed Mar 01 00:00:00 EST 2023
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang C,Lu T,Liu M,Yuan X,Li D,Zhang J,Zhou L,Xu M
Wed Mar 01 00:00:00 EST 2023
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang C,Lu T,Liu M,Yuan X,Li D,Zhang J,Zhou L,Xu M
Wed Mar 01 00:00:00 EST 2023
miR-1273h-5p protects the human corneal epithelium against UVR-induced oxidative stress and apoptosis: Role of miR-1273h-5p in climatic droplet keratopathy.
Experimental eye research
Hua Z,Shi R,Han X,Li G,Lv L,Jianimuhan N,Ma D,Cai L,Hu F,Yang J
Tue Aug 01 00:00:00 EDT 2023
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway.
Free radical biology & medicine
Lu Q,Yang L,Xiao JJ,Liu Q,Ni L,Hu JW,Yu H,Wu X,Zhang BF
Wed Feb 01 00:00:00 EST 2023
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Ecotoxicology and environmental safety
Guo C,Lyu Y,Xia S,Ren X,Li Z,Tian F,Zheng J
Sun Jan 01 00:00:00 EST 2023
Piperlongumine conjugates induce targeted protein degradation.
Cell chemical biology
Pei J,Xiao Y,Liu X,Hu W,Sobh A,Yuan Y,Zhou S,Hua N,Mackintosh SG,Zhang X,Basso KB,Kamat M,Yang Q,Licht JD,Zheng G,Zhou D,Lv D
Thu Feb 16 00:00:00 EST 2023
Blue LED light induces cytotoxicity via ROS production and mitochondrial damage in bovine subcutaneous preadipocytes.
Environmental pollution (Barking, Essex : 1987)
Hao W,Zhao C,Li G,Wang H,Li T,Yan P,Wei S
Sat Apr 01 00:00:00 EDT 2023
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis.
Journal of ethnopharmacology
Jiang H,Bai Z,Ou Y,Liu H,Si Z,Liu Y,Liu X,Liu X,Zhang Z,Tan N
Wed May 10 00:00:00 EDT 2023
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Molecular medicine (Cambridge, Mass.)
Chen Y,Liu X,Li L,He X,Zheng F,Zhang Y,Gao H,Jin Z,Wu D,Wang Q,Tao H,Zhao Y,Liu W,Zou L
Mon Feb 06 00:00:00 EST 2023
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Ecotoxicology and environmental safety
Liu X,Xi H,Han S,Zhang H,Hu J
Wed Mar 01 00:00:00 EST 2023
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Ecotoxicology and environmental safety
Liu X,Xi H,Han S,Zhang H,Hu J
Wed Mar 01 00:00:00 EST 2023
Baicalin ameliorates high fat diet-induced nonalcoholic fatty liver disease in mice via adenosine monophosphate-activated protein kinase-mediated regulation of SREBP1/Nrf2/NF-κB signaling pathways.
Phytotherapy research : PTR
Gao Y,Liu J,Hao Z,Sun N,Guo J,Zheng X,Sun P,Yin W,Fan K,Li H
Thu Jun 01 00:00:00 EDT 2023
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Frontiers in pharmacology
Liu X,Peng X,Cen S,Yang C,Ma Z,Shi X
Tue Mar 14 00:00:00 EDT 2023
Ethylhexadecyldimethylammonium bromide, a quaternary ammonium compound, controls inflammatory response through NRF2 pathway in a human immortalized keratinocyte cell line.
Frontiers in toxicology
Aubry L,Vallion R,Salman S,Damiens MH,Ferret PJ,Kerdine-Römer S
Tue Apr 25 00:00:00 EDT 2023
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways.
Biomolecules & biomedicine
Zhang H,Zeng J,Li J,Gong H,Chen M,Li Q,Liu S,Luo S,Dong H,Xu Y,Duan H,Haung L,Lv C
Mon May 01 00:00:00 EDT 2023
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways.
Biomolecules & biomedicine
Zhang H,Zeng J,Li J,Gong H,Chen M,Li Q,Liu S,Luo S,Dong H,Xu Y,Duan H,Haung L,Lv C
Mon May 01 00:00:00 EDT 2023
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways.
Biomolecules & biomedicine
Zhang H,Zeng J,Li J,Gong H,Chen M,Li Q,Liu S,Luo S,Dong H,Xu Y,Duan H,Haung L,Lv C
Mon May 01 00:00:00 EDT 2023
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways.
Biomolecules & biomedicine
Zhang H,Zeng J,Li J,Gong H,Chen M,Li Q,Liu S,Luo S,Dong H,Xu Y,Duan H,Haung L,Lv C
Mon May 01 00:00:00 EDT 2023
TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1.
Oncogene
Wei J,Wang L,Zhang Y,Sun T,Zhang C,Hu Z,Zhou L,Liu X,Wan J,Ma L
Thu Jun 01 00:00:00 EDT 2023
TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1.
Oncogene
Wei J,Wang L,Zhang Y,Sun T,Zhang C,Hu Z,Zhou L,Liu X,Wan J,Ma L
Thu Jun 01 00:00:00 EDT 2023
Triterpenoids from Uncaria macrophylla as ferroptosis inhibitors.
Phytochemistry
Liang X,Wei Y,Hou X,Guo Q,Liang H,Zeng K,Tu P,Zhang Q
Wed Feb 01 00:00:00 EST 2023
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells.
Tissue engineering and regenerative medicine
Zhang Y,Wang P,Jin MX,Zhou YQ,Ye L,Zhu XJ,Li HF,Zhou M,Li Y,Li S,Liang KY,Wang Y,Gao Y,Pan MX,Zhou SQ,Peng Q
Thu Jun 01 00:00:00 EDT 2023
Resolvin D1/N-formyl peptide receptor 2 ameliorates paclitaxel-induced neuropathic pain through the activation of IL-10/Nrf2/HO-1 pathway in mice.
Frontiers in immunology
Su CJ,Zhang JT,Zhao FL,Xu DL,Pan J,Liu T
Fri Mar 31 00:00:00 EDT 2023
Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway.
CNS neuroscience & therapeutics
Xuan LN,Hu ZX,Jiang ZF,Zhang C,Sun XW,Ming WH,Liu HT,Qiao RF,Shen LJ,Liu SB,Wang GY,Wen L,Luan ZL,Yin J
Wed Nov 01 00:00:00 EDT 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress.
Scientific reports
Pei Z,Ji J,Gao Y,Wang H,Wu Y,Yang J,Yang Q,Zhang L
Mon Jun 05 00:00:00 EDT 2023
Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress.
Scientific reports
Pei Z,Ji J,Gao Y,Wang H,Wu Y,Yang J,Yang Q,Zhang L
Mon Jun 05 00:00:00 EDT 2023
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways.
The Journal of pharmacy and pharmacology
Zhang M,Zhang J,Zhu QM,Zhao WY,Lv X,Yi J,Huo XK,Wang MJ,Sun CP
Wed Feb 08 00:00:00 EST 2023
Protective effect and mechanism of Lycium ruthenicum polyphenols against acrylamide-induced neurotoxicity.
Food & function
Pang Y,Chen J,Yang J,Xue Y,Gao H,Gao Q
Mon May 22 00:00:00 EDT 2023
Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice.
International urology and nephrology
Wang ZS,Shu B,Han Q,Li GH,Guo YL
Sun Oct 01 00:00:00 EDT 2023
Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice.
International urology and nephrology
Wang ZS,Shu B,Han Q,Li GH,Guo YL
Sun Oct 01 00:00:00 EDT 2023
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies.
Redox biology
Härkönen J,Pölönen P,Deen AJ,Selvarajan I,Teppo HR,Dimova EY,Kietzmann T,Ahtiainen M,Väyrynen JP,Väyrynen SA,Elomaa H,Tynkkynen N,Eklund T,Kuopio T,Talvitie EM,Taimen P,Kallajoki M,Kaikkonen MU,Heinäniemi M,Levonen AL
Mon May 01 00:00:00 EDT 2023
Ebselen alleviates white matter lesions and improves cognitive deficits by attenuating oxidative stress via Keap1/Nrf2 pathway in chronic cerebral hypoperfusion mice.
Behavioural brain research
Dong F,Yan W,Meng Q,Song X,Cheng B,Liu Y,Yao R
Sun Jun 25 00:00:00 EDT 2023
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Dalton transactions (Cambridge, England : 2003)
Zheng H,Hu C,Quan Y,Ye X,Shi X,Guo Z,Wang X
Tue Jun 06 00:00:00 EDT 2023
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Dalton transactions (Cambridge, England : 2003)
Zheng H,Hu C,Quan Y,Ye X,Shi X,Guo Z,Wang X
Tue Jun 06 00:00:00 EDT 2023
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Molecular biology reports
Zou X,Liu C,Huang Z,Xiang S,Li K,Yuan Y,Hao Y,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Molecular biology reports
Zou X,Liu C,Huang Z,Xiang S,Li K,Yuan Y,Hao Y,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Melatonin Alleviates the Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2 (NFE2L2)/ROS/NLRP3 Pathway.
Molecular neurobiology
Zheng Y,Gao N,Zhang W,Ma R,Chi F,Gao Z,Cong N
Wed Feb 01 00:00:00 EST 2023
Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt-GSK-3β-Nrf2 pathway.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Liu X,Liu Y,Chen L,Zhang Z,Cui L,Wei T
Wed Mar 01 00:00:00 EST 2023
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu H,Yan S,Jin M,Wei Y,Zhao L,Cheng J,Ding L,Feng H
Mon May 01 00:00:00 EDT 2023
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu H,Yan S,Jin M,Wei Y,Zhao L,Cheng J,Ding L,Feng H
Mon May 01 00:00:00 EDT 2023
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu H,Yan S,Jin M,Wei Y,Zhao L,Cheng J,Ding L,Feng H
Mon May 01 00:00:00 EDT 2023
Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo.
Redox biology
Park SY,Gurung R,Hwang JH,Kang JH,Jung HJ,Zeb A,Hwang JI,Park SJ,Maeng HJ,Shin D,Oh SH
Tue Aug 01 00:00:00 EDT 2023
Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo.
Redox biology
Park SY,Gurung R,Hwang JH,Kang JH,Jung HJ,Zeb A,Hwang JI,Park SJ,Maeng HJ,Shin D,Oh SH
Tue Aug 01 00:00:00 EDT 2023
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Investigative ophthalmology & visual science
Shu N,Zhang Z,Wang X,Li R,Li W,Liu X,Zhang Q,Jiang Z,Tao L,Zhang L,Hou S
Mon May 01 00:00:00 EDT 2023
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Xia W,Xiao J,Tong C,Lu J,Tu Y,Li S,Ni L,Shi Y,Luo P,Zhang X,Wang X
Wed Nov 01 00:00:00 EDT 2023
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Xia W,Xiao J,Tong C,Lu J,Tu Y,Li S,Ni L,Shi Y,Luo P,Zhang X,Wang X
Wed Nov 01 00:00:00 EDT 2023
Polysaccharides extracted from mulberry fruits (Morus nigra L.): antioxidant effect of ameliorating H2O2-induced liver injury in HepG2 cells.
BMC complementary medicine and therapies
Li X,Hua Y,Yang C,Liu S,Tan L,Guo J,Li Y
Wed Apr 12 00:00:00 EDT 2023
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Cell cycle (Georgetown, Tex.)
Qi D,Chen P,Bao H,Zhang L,Sun K,Song S,Li T
Sat Apr 01 00:00:00 EDT 2023
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Cell cycle (Georgetown, Tex.)
Qi D,Chen P,Bao H,Zhang L,Sun K,Song S,Li T
Sat Apr 01 00:00:00 EDT 2023
Melatonin reduces IL-33 and TSLP expression in human nasal epithelial cells by scavenging ROS directly.
Immunity, inflammation and disease
Gong MJ,Zhang HB,Lou M,Wang YS,Ma RP,Hu ZZ,Zheng GX,Zhang Y
Wed Feb 01 00:00:00 EST 2023
Melatonin reduces IL-33 and TSLP expression in human nasal epithelial cells by scavenging ROS directly.
Immunity, inflammation and disease
Gong MJ,Zhang HB,Lou M,Wang YS,Ma RP,Hu ZZ,Zheng GX,Zhang Y
Wed Feb 01 00:00:00 EST 2023
Oxidative stress and cellular toxicity induced by dihydropyrazine: a comparative study with other Maillard reaction products.
The Journal of toxicological sciences
Miyauchi Y,Koba H,Sawai M,Kansui H,Takechi S
Tue May 02 00:00:00 EDT 2023
Anti-inflammatory activity of 2-methoxy-4-vinylphenol involves inhibition of lipopolysaccharide-induced inducible nitric oxidase synthase by heme oxygenase-1.
Immunopharmacology and immunotoxicology
Asami E,Kitami M,Ida T,Kobayashi T,Saeki M
Sun Oct 01 00:00:00 EDT 2023
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Neurochemical research
Huang Y,Liu Z,Wang X,Li Y,Liu L,Li B
Fri Sep 01 00:00:00 EDT 2023
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Neurochemical research
Huang Y,Liu Z,Wang X,Li Y,Liu L,Li B
Fri Sep 01 00:00:00 EDT 2023
Cell state transition analysis identifies interventions that improve control of M. tuberculosis infection by susceptible macrophages.
bioRxiv : the preprint server for biology
Yabaji SM,Rukhlenko OS,Chatterjee S,Bhattacharya B,Wood E,Kasaikina M,Kholodenko B,Gimelbrant AA,Kramnik I
Fri Feb 10 00:00:00 EST 2023
RTA dh404 Induces Cell Cycle Arrest, Apoptosis, and Autophagy in Glioblastoma Cells.
International journal of molecular sciences
Tsai TH,Su YF,Tsai CY,Wu CH,Lee KT,Hsu YC
Thu Feb 16 00:00:00 EST 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Ferroptosis Inducers Kill Mesenchymal Stem Cells Affected by Neuroblastoma.
Cancers
Li X,Wang Q,Xu C,Zhang L,Zhou J,Lv J,Xu M,Jiang D
Sat Feb 18 00:00:00 EST 2023
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang J,Zhang L,Wang T,Zhang J,Li M,Jin X,Tan X,Wang G,Zhao F,Jin Y
Thu Jun 01 00:00:00 EDT 2023
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang J,Zhang L,Wang T,Zhang J,Li M,Jin X,Tan X,Wang G,Zhao F,Jin Y
Thu Jun 01 00:00:00 EDT 2023
Diterpenoids with anti-inflammatory activity from Euphorbia wallichii.
Phytochemistry
Wang Y,Sun D,Jiang Q,Xiong L,Zhang N,Pan Y,Li H,Chen L
Sun Jan 01 00:00:00 EST 2023
Diterpenoids with anti-inflammatory activity from Euphorbia wallichii.
Phytochemistry
Wang Y,Sun D,Jiang Q,Xiong L,Zhang N,Pan Y,Li H,Chen L
Sun Jan 01 00:00:00 EST 2023
Chemical constituents from the stems and leaves of Amomum villosum Lour. and their anti-inflammatory and antioxidant activities.
Bioorganic chemistry
Gao C,Zhu M,Xu W,Wang Y,Xiong L,Sun D,Sun M,Lin Y,Li H,Chen L
Wed Feb 01 00:00:00 EST 2023
Protective effects of baicalin against L-glutamate-induced oxidative damage in HT-22 cells by inhibiting NLRP3 inflammasome activation via Nrf2/HO-1 signaling.
Iranian journal of basic medical sciences
Li J,Wang G,Zhang Y,Fan X,Yao M
Wed Mar 01 00:00:00 EST 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Nanodrug rescues liver fibrosis via synergistic therapy with H2O2 depletion and Saikosaponin b1 sustained release.
Communications biology
Dong H,Han X,Hao M,Yang Q,Lyu Q,Tang D,Shen Z,Wang K,Kuang H,Cao G,Peng M,Shao M
Thu Feb 16 00:00:00 EST 2023
Farnesol Exerts Protective Effects against Chronic Sleep Deprivation-Induced Cognitive Impairment via Activation SIRT1/Nrf2 Pathway in the Hippocampi of Adult Mice.
Molecular nutrition & food research
Li Y,Xie Z,Luo X,Wang X,Wang Y,Guo M,Zhou Z,Sun R,Hua D,Luo A,Li S
Thu Jun 01 00:00:00 EDT 2023
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
ACS central science
Zhang J,Zhang M,Huo XK,Ning J,Yu ZL,Morisseau C,Sun CP,Hammock BD,Ma XC
Wed Mar 22 00:00:00 EDT 2023
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
ACS central science
Zhang J,Zhang M,Huo XK,Ning J,Yu ZL,Morisseau C,Sun CP,Hammock BD,Ma XC
Wed Mar 22 00:00:00 EDT 2023
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Digestive diseases and sciences
Yang J,Han F,Wu G,Dong Y,Su H,Xu J,Li J
Wed Feb 01 00:00:00 EST 2023
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11.
Neurotoxicity research
Lin S,Cheng H,Yang G,Wang C,Leung CK,Zhang S,Tan Y,Zhang H,Wang H,Miao L,Li Y,Huang Y,Li J,Zhang R,Zeng X
Sun Oct 01 00:00:00 EDT 2023
Involvements of Nrf2 and oxidative stress in the ozone-elicited exacerbation in an allergic rhinitis model.
Ecotoxicology and environmental safety
Sun N,Huang Y,Zhang X,Niu Y,Duan Y,Kan H,Zhang R
Sat Apr 15 00:00:00 EDT 2023
Involvements of Nrf2 and oxidative stress in the ozone-elicited exacerbation in an allergic rhinitis model.
Ecotoxicology and environmental safety
Sun N,Huang Y,Zhang X,Niu Y,Duan Y,Kan H,Zhang R
Sat Apr 15 00:00:00 EDT 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress.
Cell death discovery
Wang Y,Zan Y,Huang Y,Peng X,Ma S,Ren J,Li X,Wei L,Wang X,Yuan Y,Tang J,Zhan Z,Wang Z,Ding Y
Sat Feb 04 00:00:00 EST 2023
NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress.
Cell death discovery
Wang Y,Zan Y,Huang Y,Peng X,Ma S,Ren J,Li X,Wei L,Wang X,Yuan Y,Tang J,Zhan Z,Wang Z,Ding Y
Sat Feb 04 00:00:00 EST 2023
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Free radical biology & medicine
Fan J,Xu X,Li Y,Zhang L,Miao M,Niu Y,Zhang Y,Zhang A,Jia Z,Wu M
Sun Jan 01 00:00:00 EST 2023
Protective effect of human umbilical cord mesenchymal stem cell derived conditioned medium in a mutant TDP-43 induced motoneuron-like cellular model of ALS.
Brain research bulletin
Lan J,Zhou Y,Wang H,Tang J,Kang Y,Wang P,Liu X,Peng Y
Wed Feb 01 00:00:00 EST 2023
Protective effect of human umbilical cord mesenchymal stem cell derived conditioned medium in a mutant TDP-43 induced motoneuron-like cellular model of ALS.
Brain research bulletin
Lan J,Zhou Y,Wang H,Tang J,Kang Y,Wang P,Liu X,Peng Y
Wed Feb 01 00:00:00 EST 2023
Polysaccharide from Flammulina velutipes residues protects mice from Pb poisoning by activating Akt/GSK3β/Nrf-2/HO-1 signaling pathway and modulating gut microbiota.
International journal of biological macromolecules
Liu Y,Li H,Ren P,Che Y,Zhou J,Wang W,Yang Y,Guan L
Wed Mar 01 00:00:00 EST 2023
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
European journal of pharmacology
Wu Y,Wu Y,Yu J,Zhang Y,Li Y,Fu R,Sun Y,Zhao K,Xiao Q
Sun Jan 15 00:00:00 EST 2023
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory biomarkers and mitochondria apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wang G,Sun Y,Yang Q,Dai D,Zhang L,Fan H,Zhang W,Dong J,Zhao P
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1-Mediated NRF2 Ubiquitination.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang X,Zhou T,Yang X,Cao X,Jin G,Zhang P,Guo J,Rong K,Li B,Hu Y,Liu K,Ma P,Qin A,Zhao J
Mon May 01 00:00:00 EDT 2023
DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1-Mediated NRF2 Ubiquitination.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang X,Zhou T,Yang X,Cao X,Jin G,Zhang P,Guo J,Rong K,Li B,Hu Y,Liu K,Ma P,Qin A,Zhao J
Mon May 01 00:00:00 EDT 2023
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Toxicology
Li M,Li T,Yin J,Xie C,Zhu J
Sun Jan 15 00:00:00 EST 2023
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Toxicology
Li M,Li T,Yin J,Xie C,Zhu J
Sun Jan 15 00:00:00 EST 2023
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Frontiers in pharmacology
Kou Y,Rong X,Tang R,Zhang Y,Yang P,Liu H,Ma W,Li M
Tue Mar 21 00:00:00 EDT 2023
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal.
Frontiers in pharmacology
Kou Y,Rong X,Tang R,Zhang Y,Yang P,Liu H,Ma W,Li M
Tue Mar 21 00:00:00 EDT 2023
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.
Free radical biology & medicine
Zhu H,Yan C,Yao P,Li P,Li Y,Yang H
Tue Aug 01 00:00:00 EDT 2023
CircRNA MBOAT2 promotes intrahepatic cholangiocarcinoma progression and lipid metabolism reprogramming by stabilizing PTBP1 to facilitate FASN mRNA cytoplasmic export.
Cell death & disease
Yu X,Tong H,Chen J,Tang C,Wang S,Si Y,Wang S,Tang Z
Thu Jan 12 00:00:00 EST 2023
Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense.
Frontiers in immunology
Adzika GK,Mprah R,Rizvi R,Adekunle AO,Ndzie Noah ML,Wowui PI,Adzraku SY,Adu-Amankwaah J,Wang F,Lin Y,Fu L,Liu X,Xiang J,Sun H
Tue Mar 07 00:00:00 EST 2023
Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss.
International immunopharmacology
Guo J,Ren R,Guo Z,Sun K,He J,Shao J,Wang X
Wed Mar 01 00:00:00 EST 2023
Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss.
International immunopharmacology
Guo J,Ren R,Guo Z,Sun K,He J,Shao J,Wang X
Wed Mar 01 00:00:00 EST 2023
LncRNA UCA1 promoted cisplatin resistance in lung adenocarcinoma with HO1 targets NRF2/HO1 pathway.
Journal of cancer research and clinical oncology
Shi W,Ling L,Li C,Wu R,Zhang M,Shao F,Wang Y
Wed Mar 01 00:00:00 EST 2023
Ro25-6981 alleviates neuronal damage and improves cognitive deficits by attenuating oxidative stress via the Nrf2/ARE pathway in ischemia/reperfusion rats.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Gao X,Chen F,Xu X,Liu J,Dong F,Liu Y
Wed Mar 01 00:00:00 EST 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ma D,Wang Z,He Z,Wang Z,Chen Q,Qin F,Zeng M,Chen J
Sun Jan 01 00:00:00 EST 2023
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ma D,Wang Z,He Z,Wang Z,Chen Q,Qin F,Zeng M,Chen J
Sun Jan 01 00:00:00 EST 2023
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Aging cell
Li J,Zhang J,Xue Q,Liu B,Qin R,Li Y,Qiu Y,Wang R,Goltzman D,Miao D,Yang R
Fri Sep 01 00:00:00 EDT 2023
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Aging cell
Li J,Zhang J,Xue Q,Liu B,Qin R,Li Y,Qiu Y,Wang R,Goltzman D,Miao D,Yang R
Fri Sep 01 00:00:00 EDT 2023
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Aging cell
Li J,Zhang J,Xue Q,Liu B,Qin R,Li Y,Qiu Y,Wang R,Goltzman D,Miao D,Yang R
Fri Sep 01 00:00:00 EDT 2023
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Aging cell
Li J,Zhang J,Xue Q,Liu B,Qin R,Li Y,Qiu Y,Wang R,Goltzman D,Miao D,Yang R
Fri Sep 01 00:00:00 EDT 2023
Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process.
Toxicology letters
Hou Z,Yan M,Li H,Wang W,You S,Wang M,Du T,Gong H,Li W,Guo L,Wei S,Zhang B,Ji M,Chen X
Sat Apr 15 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Cigarette smoke induces the ROS accumulation and iNOS activation through deactivation of Nrf-2/SIRT3 axis to mediate the human bronchial epithelium ferroptosis.
Free radical biology & medicine
Zi Y,Wang X,Zi Y,Yu H,Lan Y,Fan Y,Ren C,Liao K,Chen H
Mon May 01 00:00:00 EDT 2023
Cold atmospheric plasma alleviates radiation-induced skin injury by suppressing inflammation and promoting repair.
Free radical biology & medicine
Ma L,Chen Y,Gong Q,Cheng Z,Ran C,Liu K,Shi C
Tue Aug 01 00:00:00 EDT 2023
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation.
Food & function
Li H,Weng Q,Gong S,Zhang W,Wang J,Huang Y,Li Y,Guo J,Lan T
Tue Feb 21 00:00:00 EST 2023
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation.
Food & function
Li H,Weng Q,Gong S,Zhang W,Wang J,Huang Y,Li Y,Guo J,Lan T
Tue Feb 21 00:00:00 EST 2023
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation.
Food & function
Li H,Weng Q,Gong S,Zhang W,Wang J,Huang Y,Li Y,Guo J,Lan T
Tue Feb 21 00:00:00 EST 2023
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation.
Food & function
Li H,Weng Q,Gong S,Zhang W,Wang J,Huang Y,Li Y,Guo J,Lan T
Tue Feb 21 00:00:00 EST 2023
Lansoprazole protects hepatic cells against cisplatin-induced oxidative stress through the p38 MAPK/ARE/Nrf2 pathway.
PloS one
Yamagishi N,Yamamoto Y,Nishi T,Ito T,Kanai Y
Mon Jul 03 00:00:00 EDT 2023
Red Ginseng Improves D-galactose-Induced Premature Ovarian Failure in Mice Based on Network Pharmacology.
International journal of molecular sciences
Shang Z,Fan M,Zhang J,Wang Z,Jiang S,Li W
Thu May 04 00:00:00 EDT 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Andrographolide-treated bone marrow mesenchymal stem cells-derived conditioned medium protects cardiomyocytes from injury by metabolic remodeling.
Molecular biology reports
Sun Y,Xu H,Tan B,Yi Q,Liu H,Tian J,Zhu J
Wed Mar 01 00:00:00 EST 2023
Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway.
Archives of biochemistry and biophysics
Chen X,Song QL,Li ZH,Ji R,Wang JY,Cao ML,Mu XF,Zhang Y,Guo DY,Yang J
Sat Apr 01 00:00:00 EDT 2023
Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis.
Redox biology
Liu S,Zhang HL,Li J,Ye ZP,Du T,Li LC,Guo YQ,Yang D,Li ZL,Cao JH,Hu BX,Chen YH,Feng GK,Li ZM,Deng R,Huang JJ,Zhu XF
Thu Jun 01 00:00:00 EDT 2023
Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis.
Redox biology
Liu S,Zhang HL,Li J,Ye ZP,Du T,Li LC,Guo YQ,Yang D,Li ZL,Cao JH,Hu BX,Chen YH,Feng GK,Li ZM,Deng R,Huang JJ,Zhu XF
Thu Jun 01 00:00:00 EDT 2023
NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors.
Redox biology
Zhong Z,Zhang C,Ni S,Ma M,Zhang X,Sang W,Lv T,Qian Z,Yi C,Yu B
Sat Jul 01 00:00:00 EDT 2023
Dental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress.
Journal of inflammation research
Gao X,Liu Z,Wang Z
Tue Apr 18 00:00:00 EDT 2023
Dental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress.
Journal of inflammation research
Gao X,Liu Z,Wang Z
Tue Apr 18 00:00:00 EDT 2023
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
EBioMedicine
Wang Y,Tang B,Li H,Zheng J,Zhang C,Yang Z,Tan X,Luo P,Ma L,Wang Y,Long L,Chen Z,Xiao Z,Ma L,Zhou J,Wang Y,Shi C
Sat Apr 01 00:00:00 EDT 2023
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
EBioMedicine
Wang Y,Tang B,Li H,Zheng J,Zhang C,Yang Z,Tan X,Luo P,Ma L,Wang Y,Long L,Chen Z,Xiao Z,Ma L,Zhou J,Wang Y,Shi C
Sat Apr 01 00:00:00 EDT 2023
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
EBioMedicine
Wang Y,Tang B,Li H,Zheng J,Zhang C,Yang Z,Tan X,Luo P,Ma L,Wang Y,Long L,Chen Z,Xiao Z,Ma L,Zhou J,Wang Y,Shi C
Sat Apr 01 00:00:00 EDT 2023
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
EBioMedicine
Wang Y,Tang B,Li H,Zheng J,Zhang C,Yang Z,Tan X,Luo P,Ma L,Wang Y,Long L,Chen Z,Xiao Z,Ma L,Zhou J,Wang Y,Shi C
Sat Apr 01 00:00:00 EDT 2023
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
Neural regeneration research
Wang J,He P,Tian Q,Luo Y,He Y,Liu C,Gong P,Guo Y,Ye Q,Li M
Fri Sep 01 00:00:00 EDT 2023
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Pharmaceutical biology
Ding J,Lu B,Liu L,Zhong Z,Wang N,Li B,Sheng W,He Q
Fri Dec 01 00:00:00 EST 2023
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
International immunopharmacology
Wang J,Ren B,Yang Y,Li Y
Mon May 01 00:00:00 EDT 2023
Ampicillin exacerbates acetaminophen-induced acute liver injury by inducing intestinal microbiota imbalance and butyrate reduction.
Liver international : official journal of the International Association for the Study of the Liver
Li ZM,Kong CY,Mao YQ,Huang JT,Chen HL,Han B,Wang LS
Sat Apr 01 00:00:00 EDT 2023
Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies.
Eye and vision (London, England)
Li K,Gong Q,Lu B,Huang K,Tong Y,Mutsvene TE,Lin M,Xu Z,Lu F,Li X,Hu L
Mon May 01 00:00:00 EDT 2023
Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies.
Eye and vision (London, England)
Li K,Gong Q,Lu B,Huang K,Tong Y,Mutsvene TE,Lin M,Xu Z,Lu F,Li X,Hu L
Mon May 01 00:00:00 EDT 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 EST 2023
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
Journal of agricultural and food chemistry
Hu P,Liu Y,Li S,Zhao Y,Gu H,Zong Q,Ahmed AA,Bao W,Liu HY,Cai D
Wed May 31 00:00:00 EDT 2023
Epigallocatechin-3-gallate (EGCG) based metal-polyphenol nanoformulations alleviates chondrocytes inflammation by modulating synovial macrophages polarization.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wei H,Qin J,Huang Q,Jin Z,Zheng L,Zhao J,Qin Z
Mon May 01 00:00:00 EDT 2023
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Materials today. Bio
Dai Z,Xia C,Zhao T,Wang H,Tian H,Xu O,Zhu X,Zhang J,Chen P
Wed Feb 01 00:00:00 EST 2023
Glycyrrhizin protects against particulate matter-induced lung injury via regulation of endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis through Nrf2/HO-1/NQO1 signaling pathway.
International immunopharmacology
Shi Q,Qian Y,Wang B,Liu L,Chen Y,Chen C,Feng L,Chen J,Dong N
Sat Jul 01 00:00:00 EDT 2023
Oral administration of Lactobacillus plantarum JC7 alleviates OVA-induced murine food allergy through immunoregulation and restoring disordered intestinal microbiota.
European journal of nutrition
Duan C,Ma L,Yu J,Sun Y,Liu L,Ma F,Li X,Li D
Wed Mar 01 00:00:00 EST 2023
Ammonia-induced oxidative stress triggered proinflammatory response and apoptosis in pig lungs.
Journal of environmental sciences (China)
Li D,Shen L,Zhang D,Wang X,Wang Q,Qin W,Gao Y,Li X
Sat Apr 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Nan P,Gong Y,Tian L,Zheng Y,Wu Z
Tue Aug 01 00:00:00 EDT 2023
Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.
The Journal of nutrition
Wang G,Qin S,Geng H,Zheng Y,Li R,Xia C,Chen L,Yao J,Deng L
Sat Jul 01 00:00:00 EDT 2023
Anti-Inflammatory Effects of New Naphthyridine from Sponge Aaptos suberitoides in LPS-Stimulated RAW 264.7 Macrophages via Regulation of MAPK and Nrf2 Signaling Pathways.
Chemistry & biodiversity
Liu M,Zhang Z,He Q,Qi S,Sun K,Miao S,Wu Y,Gong K
Thu Jun 01 00:00:00 EDT 2023
Photobiomodulation Controls Keratinocytes Inflammatory Response through Nrf2 and Reduces Langerhans Cells Activation.
Antioxidants (Basel, Switzerland)
Salman S,Guermonprez C,Peno-Mazzarino L,Lati E,Rousseaud A,Declercq L,Kerdine-Römer S
Tue Mar 21 00:00:00 EDT 2023
Long noncoding RNA PSMA3-AS1 functions as a competing endogenous RNA to promote gastric cancer progression by regulating the miR-329-3p/ALDOA axis.
Biology direct
Kan L,Yang M,Zhang H
Tue Jul 04 00:00:00 EDT 2023
Dopamine D1 receptor activation ameliorates ox-LDL-induced endothelial cell senescence via CREB/Nrf2 pathway.
Experimental cell research
Zhao Y,Li Y,Li H,Shi S
Sat Apr 15 00:00:00 EDT 2023
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Journal of ethnopharmacology
Zhang X,Wang S,Jin Y,Wang J,Wang R,Yang X,Zhang S,Yan T,Jia Y
Tue May 23 00:00:00 EDT 2023
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
International journal of biological macromolecules
Xu Q,Zhang P,Han X,Ren H,Yu W,Hao W,Luo B,Khan MI,Chen N
Fri Jun 30 00:00:00 EDT 2023
Wild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways.
Journal of pharmacological sciences
Idera A,Sharkey LM,Kurauchi Y,Kadoyama K,Paulson HL,Katsuki H,Seki T
Sat Jul 01 00:00:00 EDT 2023
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Gastroenterology
Yang XM,Wang XQ,Hu LP,Feng MX,Zhou YQ,Li DX,Li J,Miao XC,Zhang YL,Yao LL,Nie HZ,Huang S,Xia Q,Zhang XL,Jiang SH,Zhang ZG
Fri Sep 01 00:00:00 EDT 2023
DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis.
Cellular signalling
Chu X,Zhong L,Dan W,Wang X,Zhang Z,Liu Z,Lu Y,Shao X,Zhou Z,Chen S,Liu B
Mon May 01 00:00:00 EDT 2023
Ginsenoside ompound K reduces neuronal damage and improves neuronal synaptic dysfunction by targeting Aβ.
Frontiers in pharmacology
Li N,Pang Q,Zhang Y,Lin J,Li H,Li Z,Liu Y,Fang X,An Y,Bai H,Li D,Cao Z,Liu J,Yang Q,Hu S
Tue Mar 07 00:00:00 EST 2023
Ginsenoside ompound K reduces neuronal damage and improves neuronal synaptic dysfunction by targeting Aβ.
Frontiers in pharmacology
Li N,Pang Q,Zhang Y,Lin J,Li H,Li Z,Liu Y,Fang X,An Y,Bai H,Li D,Cao Z,Liu J,Yang Q,Hu S
Tue Mar 07 00:00:00 EST 2023
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Biomedicines
Hu W,Yang J,Xue J,Ma J,Wu S,Wang J,Xu R,Wei J,Wang Y,Wang S,Liu X
Sun Feb 05 00:00:00 EST 2023
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Biomedicines
Hu W,Yang J,Xue J,Ma J,Wu S,Wang J,Xu R,Wei J,Wang Y,Wang S,Liu X
Sun Feb 05 00:00:00 EST 2023
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Biomedicines
Hu W,Yang J,Xue J,Ma J,Wu S,Wang J,Xu R,Wei J,Wang Y,Wang S,Liu X
Sun Feb 05 00:00:00 EST 2023
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Biomedicines
Hu W,Yang J,Xue J,Ma J,Wu S,Wang J,Xu R,Wei J,Wang Y,Wang S,Liu X
Sun Feb 05 00:00:00 EST 2023
Oxazole-4-carboxamide/butylated hydroxytoluene hybrids with GSK-3β inhibitory and neuroprotective activities against Alzheimer's disease.
European journal of medicinal chemistry
Luo Z,Li S,Zhang Y,Yin F,Luo H,Chen X,Cui N,Wan S,Li X,Kong L,Wang X
Sat Aug 05 00:00:00 EDT 2023
Drug repurposing of ilepcimide that ameliorates experimental autoimmune encephalomyelitis via restricting inflammatory response and oxidative stress.
Toxicology and applied pharmacology
Xu Z,Lu S,Liu X,Tang L,Liu Z,Cui J,Wang W,Lu W,Huang J
Sun Jan 01 00:00:00 EST 2023
Drug repurposing of ilepcimide that ameliorates experimental autoimmune encephalomyelitis via restricting inflammatory response and oxidative stress.
Toxicology and applied pharmacology
Xu Z,Lu S,Liu X,Tang L,Liu Z,Cui J,Wang W,Lu W,Huang J
Sun Jan 01 00:00:00 EST 2023
Isosinensetin alleviates estrogen deficiency-induced osteoporosis via suppressing ROS-mediated NF-κB/MAPK signaling pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Qin Y,Song D,Liao S,Chen J,Xu M,Su Y,Lian H,Peng H,Wei L,Chen K,Xu J,Zhao J,Liu Q
Sat Apr 01 00:00:00 EDT 2023
Rivaroxaban Combined with Atorvastatin Inhibits Acute Pulmonary Embolism by Promoting the Expression of NRF2/NQO1.
Cardiovascular drugs and therapy
Chen Y,Fan C,Wang J,Jiang M
Thu Jun 15 00:00:00 EDT 2023
Rivaroxaban Combined with Atorvastatin Inhibits Acute Pulmonary Embolism by Promoting the Expression of NRF2/NQO1.
Cardiovascular drugs and therapy
Chen Y,Fan C,Wang J,Jiang M
Thu Jun 15 00:00:00 EDT 2023
Rivaroxaban Combined with Atorvastatin Inhibits Acute Pulmonary Embolism by Promoting the Expression of NRF2/NQO1.
Cardiovascular drugs and therapy
Chen Y,Fan C,Wang J,Jiang M
Thu Jun 15 00:00:00 EDT 2023
Rivaroxaban Combined with Atorvastatin Inhibits Acute Pulmonary Embolism by Promoting the Expression of NRF2/NQO1.
Cardiovascular drugs and therapy
Chen Y,Fan C,Wang J,Jiang M
Thu Jun 15 00:00:00 EDT 2023
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Free radical biology & medicine
Zhang Z,Cheng J,Yang L,Li X,Hua R,Xu D,Jiang Z,Li Q
Mon May 01 00:00:00 EDT 2023
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen RJ,Dong X,Zhuang HW,Pang FX,Ding SC,Li N,Mai YX,Zhou ST,Wang JY,Zhang JF
Tue Jul 25 00:00:00 EDT 2023
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen RJ,Dong X,Zhuang HW,Pang FX,Ding SC,Li N,Mai YX,Zhou ST,Wang JY,Zhang JF
Tue Jul 25 00:00:00 EDT 2023
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen RJ,Dong X,Zhuang HW,Pang FX,Ding SC,Li N,Mai YX,Zhou ST,Wang JY,Zhang JF
Tue Jul 25 00:00:00 EDT 2023
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen RJ,Dong X,Zhuang HW,Pang FX,Ding SC,Li N,Mai YX,Zhou ST,Wang JY,Zhang JF
Tue Jul 25 00:00:00 EDT 2023
A Rational Design of Metal-Organic Framework Nanozyme with High-Performance Copper Active Centers for Alleviating Chemical Corneal Burns.
Nano-micro letters
Tang Y,Han Y,Zhao J,Lv Y,Fan C,Zheng L,Zhang Z,Liu Z,Li C,Lin Y
Sun Apr 30 00:00:00 EDT 2023
Antimicrobial peptide cathelicidin LL-37 preserves intestinal barrier and organ function in rats with heat stroke.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Shih CC,Liao WC,Ke HY,Kuo CW,Tsao CM,Tsai WC,Chiu YL,Huang HC,Wu CC
Mon May 01 00:00:00 EDT 2023
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Environmental toxicology
Xi Y,Chi Z,Tao X,Zhai X,Zhao Z,Ren J,Yang S,Dong D
Mon May 01 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
PM2.5 caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis.
The Science of the total environment
Wang J,Zhang Z,Shi F,Li Y,Tang Y,Liu C,Wang Y,Chen J,Jiang X,Yang H,Sun L,Chen Q,Ao L,Han F,Liu J,Cao J
Wed May 10 00:00:00 EDT 2023
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Neural regeneration research
Yu Z,Cheng X,Pan W,Yu C,Duan Y
Wed Nov 01 00:00:00 EDT 2023
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Neural regeneration research
Yu Z,Cheng X,Pan W,Yu C,Duan Y
Wed Nov 01 00:00:00 EDT 2023
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
The Journal of pharmacy and pharmacology
Zhang X,Yang X,Zhang S,Wang J,Wang M,Ma T,Wan M,Lv X,Yan T,Jia Y
Fri Apr 07 00:00:00 EDT 2023
Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro.
Journal of hepatocellular carcinoma
Xiu Z,Li Y,Fang J,Han J,Li S,Li Y,Yang X,Song G,Li Y,Jin N,Zhu Y,Zhu G,Sun L,Li X
Wed Apr 19 00:00:00 EDT 2023
Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro.
Journal of hepatocellular carcinoma
Xiu Z,Li Y,Fang J,Han J,Li S,Li Y,Yang X,Song G,Li Y,Jin N,Zhu Y,Zhu G,Sun L,Li X
Wed Apr 19 00:00:00 EDT 2023
Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro.
Journal of hepatocellular carcinoma
Xiu Z,Li Y,Fang J,Han J,Li S,Li Y,Yang X,Song G,Li Y,Jin N,Zhu Y,Zhu G,Sun L,Li X
Wed Apr 19 00:00:00 EDT 2023
Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro.
Journal of hepatocellular carcinoma
Xiu Z,Li Y,Fang J,Han J,Li S,Li Y,Yang X,Song G,Li Y,Jin N,Zhu Y,Zhu G,Sun L,Li X
Wed Apr 19 00:00:00 EDT 2023
Cytotoxic and Antioxidant Activity of Hypericum perforatum L. Extracts against Human Melanoma Cells from Different Stages of Cancer Progression, Cultured under Normoxia and Hypoxia.
Molecules (Basel, Switzerland)
Brankiewicz A,Trzos S,Mrożek M,Opydo M,Szostak E,Dziurka M,Tuleja M,Łoboda A,Pocheć E
Fri Feb 03 00:00:00 EST 2023
Mst1 attenuates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice through regulating Keap1/Nrf2 axis.
Biochemical and biophysical research communications
Fei Q,Liu J,Qiao L,Zhang M,Xia H,Lu D,Wu D,Wang J,Li R,Li J,Yang F,Liu D,Xie B,Hui W,Qian B
Sun Feb 12 00:00:00 EST 2023
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Journal of dairy science
Chen H,Qi X,Guan K,Wang R,Li Q,Ma Y
Sat Apr 01 00:00:00 EDT 2023
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Journal of ethnopharmacology
Zhu Y,Han Y,Wang W,Liang G,Qi J
Sat Jul 15 00:00:00 EDT 2023
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Oxidative medicine and cellular longevity
Chen Y,Zhang H,Li Y,Wang T
Mon Feb 06 00:00:00 EST 2023
Isoliquiritigenin inhibits virus replication and virus-mediated inflammation via NRF2 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang H,Jia X,Zhang M,Cheng C,Liang X,Wang X,Xie F,Wang J,Yu Y,He Y,Dong Q,Wang Y,Xu A
Thu Jun 01 00:00:00 EDT 2023
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Acta pharmacologica Sinica
Xie Z,Wu XJ,Cheng RW,Cui JH,Yuan ST,Zhou JW,Liu QH
Sat Apr 01 00:00:00 EDT 2023
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Acta pharmacologica Sinica
Xie Z,Wu XJ,Cheng RW,Cui JH,Yuan ST,Zhou JW,Liu QH
Sat Apr 01 00:00:00 EDT 2023
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Journal of ethnopharmacology
Wang SJ,Ye W,Li WY,Tian W,Zhang M,Sun Y,Feng YD,Liu CX,Liu SY,Cao W,Meng JR,Li XQ
Wed Mar 01 00:00:00 EST 2023
Dexmedetomidine postconditioning attenuates myocardial ischemia/reperfusion injury by activating the Nrf2/Sirt3/SOD2 signaling pathway in the rats.
Redox report : communications in free radical research
Hu B,Tian T,Li XT,Hao PP,Liu WC,Chen YG,Jiang TY,Chen PS,Cheng Y,Xue FS
Fri Dec 01 00:00:00 EST 2023
A Biomimetic Nanoparticle Exerting Protection against Acute Liver Failure by Suppressing CYP2E1 Activity and Scavenging Excessive ROS.
Advanced healthcare materials
Yao Q,Tang Y,Dai S,Huang L,Jiang Z,Zheng S,Sun M,Xu Y,Lu R,Sun T,Huang H,Jiang X,Yao X,Lin G,Kou L,Chen R
Fri Sep 01 00:00:00 EDT 2023
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Molecular biology reports
Wei Y,Tan W,Qin H,Jin M,Yu H,Cheng J,Feng H
Sun Jan 01 00:00:00 EST 2023
Denervation delays initial bone healing of rat tooth extraction socket.
Odontology
Sheng Z,Zheng F,Li J,Wang Y,Du Y,Liu X,Yu X
Sat Jul 01 00:00:00 EDT 2023
Denervation delays initial bone healing of rat tooth extraction socket.
Odontology
Sheng Z,Zheng F,Li J,Wang Y,Du Y,Liu X,Yu X
Sat Jul 01 00:00:00 EDT 2023
Denervation delays initial bone healing of rat tooth extraction socket.
Odontology
Sheng Z,Zheng F,Li J,Wang Y,Du Y,Liu X,Yu X
Sat Jul 01 00:00:00 EDT 2023
Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca2+ pathways in heart failure.
Redox biology
Wan S,Cui Z,Wu L,Zhang F,Liu T,Hu J,Tian J,Yu B,Liu F,Kou J,Li F
Sat Apr 01 00:00:00 EDT 2023
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Immunopharmacology and immunotoxicology
Wang X,Yang J,Wang W,Li Y,Yang Y
Sun Oct 01 00:00:00 EDT 2023
Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells.
Biological & pharmaceutical bulletin
Kawakami F,Imai M,Tamaki S,Ohta E,Kawashima R,Maekawa T,Kurosaki Y,Ohba K,Ichikawa T
Thu Jan 05 00:00:00 EST 2023
Tingli Dazao Decoction pretreatment ameliorates mitochondrial damage induced by oxidative stress in cardiomyocytes.
Journal of ethnopharmacology
Chen H,Zhu Y,Zhao X,Yang Z
Wed Mar 01 00:00:00 EST 2023
Apigenin improves cytotoxicity of antiretroviral drugs against HTLV-1 infected cells through the modulation of AhR signaling.
NeuroImmune pharmacology and therapeutics
Sales D,Lin E,Stoffel V,Dickson S,Khan ZK,Beld J,Jain P
Sat Mar 25 00:00:00 EDT 2023
Fucoidan promotes angiogenesis and accelerates wound healing through AKT/Nrf2/HIF-1α signalling pathway.
International wound journal
Wen W,Yang L,Wang X,Zhang H,Wu F,Xu K,Chen S,Liao Z
Wed Nov 01 00:00:00 EDT 2023
Fucoidan promotes angiogenesis and accelerates wound healing through AKT/Nrf2/HIF-1α signalling pathway.
International wound journal
Wen W,Yang L,Wang X,Zhang H,Wu F,Xu K,Chen S,Liao Z
Wed Nov 01 00:00:00 EDT 2023
Fucoidan promotes angiogenesis and accelerates wound healing through AKT/Nrf2/HIF-1α signalling pathway.
International wound journal
Wen W,Yang L,Wang X,Zhang H,Wu F,Xu K,Chen S,Liao Z
Wed Nov 01 00:00:00 EDT 2023
Fucoidan promotes angiogenesis and accelerates wound healing through AKT/Nrf2/HIF-1α signalling pathway.
International wound journal
Wen W,Yang L,Wang X,Zhang H,Wu F,Xu K,Chen S,Liao Z
Wed Nov 01 00:00:00 EDT 2023
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Bioactive materials
Sun H,Xu J,Wang Y,Shen S,Xu X,Zhang L,Jiang Q
Thu Jun 01 00:00:00 EDT 2023
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Bioactive materials
Sun H,Xu J,Wang Y,Shen S,Xu X,Zhang L,Jiang Q
Thu Jun 01 00:00:00 EDT 2023
Active Nrf2 signaling flexibly regulates HO-1 and NQO-1 in hypoxic Gansu Zokor (Eospalax cansus).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Li M,Peng Y,Chen W,Gao Y,Yang M,Li J,He J
Mon Jan 09 00:00:00 EST 2023
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Theriogenology
Xi H,Hu Z,Han S,Liu X,Wang L,Hu J
Sun Jan 01 00:00:00 EST 2023
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Theriogenology
Xi H,Hu Z,Han S,Liu X,Wang L,Hu J
Sun Jan 01 00:00:00 EST 2023
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Journal of medicinal chemistry
Qi M,Zhong H,Cheng Z,Chen S,Xiao H,Shang J,Chen L,Sun J
Thu Jul 13 00:00:00 EDT 2023
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Journal of medicinal chemistry
Qi M,Zhong H,Cheng Z,Chen S,Xiao H,Shang J,Chen L,Sun J
Thu Jul 13 00:00:00 EDT 2023
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Chemico-biological interactions
Li J,Bai J,Si X,Jia H,Wu Z
Sat Apr 01 00:00:00 EDT 2023
linc01515 regulates PM2.5-induced oxidative stress via targeting NRF2 in airway epithelial cells.
Environmental pollution (Barking, Essex : 1987)
Wang X,Zhu H,Sun G,Zhou M,Zhang H,Liu H,Wang M,Zhang Z,Chu H
Tue Aug 15 00:00:00 EDT 2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mi Y,Wei C,Sun L,Liu H,Zhang J,Luo J,Yu X,He J,Ge H,Liu P
Sun Jan 01 00:00:00 EST 2023
Curcumin alleviates ketamine-induced oxidative stress and apoptosis via Nrf2 signaling pathway in rats' cerebral cortex and hippocampus.
Environmental toxicology
Zhang X,Cui Y,Song X,Jin X,Sheng X,Xu X,Li T,Chen H,Gao L
Wed Feb 01 00:00:00 EST 2023
Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway.
Frontiers in pharmacology
Liu Y,Mo J,Liang F,Jiang S,Xiong J,Meng X,Mo Z
Thu Feb 02 00:00:00 EST 2023
Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.
Integrative medicine research
Weng H,Wang Q,Ye R,Bai Y,Yang H,Xu G,Wang Q
Thu Jun 01 00:00:00 EDT 2023
Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.
Integrative medicine research
Weng H,Wang Q,Ye R,Bai Y,Yang H,Xu G,Wang Q
Thu Jun 01 00:00:00 EDT 2023
17β-estradiol plays the anti-osteoporosis role via a novel ESR1-Keap1-Nrf2 axis-mediated stress response activation and Tmem119 upregulation.
Free radical biology & medicine
Yang R,Li J,Zhang J,Xue Q,Qin R,Wang R,Goltzman D,Miao D
Wed Feb 01 00:00:00 EST 2023
Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.
Journal of translational medicine
Zhang FL,Chen XW,Wang YF,Hu Z,Zhang WJ,Zhou BW,Ci PF,Liu KX
Tue Apr 18 00:00:00 EDT 2023
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.
Redox biology
Gan Y,Deng J,Hao Q,Huang Y,Han T,Xu JG,Zhao M,Yao L,Xu Y,Xiong J,Lu H,Wang C,Chen J,Zhou X
Thu Jun 01 00:00:00 EDT 2023
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.
Redox biology
Gan Y,Deng J,Hao Q,Huang Y,Han T,Xu JG,Zhao M,Yao L,Xu Y,Xiong J,Lu H,Wang C,Chen J,Zhou X
Thu Jun 01 00:00:00 EDT 2023
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
The FEBS journal
Zhang X,Li S,Ren X,Xiang P,Zhang Y,Wang T,Qin Q,Sun F,Liu J,Gao L,Ma C,Yue X,Yang X,Han S,Liang X
Wed Feb 01 00:00:00 EST 2023
Reduced SUMOylation of Nrf2 signaling contributes to its inhibition induced by amyloid-β.
Neuroscience letters
Wang P,Wang X,Qiao K,Zhang Y,Nie Q,Cui J,Sun J,Li L
Thu Mar 16 00:00:00 EDT 2023
β-Cryptoxanthin Maintains Mitochondrial Function by Promoting NRF2 Nuclear Translocation to Inhibit Oxidative Stress-Induced Senescence in HK-2 Cells.
International journal of molecular sciences
Zhang Y,Mao H,Li Y,Xiong Y,Liu X,Wang L,Chen Z
Tue Feb 14 00:00:00 EST 2023
β-Cryptoxanthin Maintains Mitochondrial Function by Promoting NRF2 Nuclear Translocation to Inhibit Oxidative Stress-Induced Senescence in HK-2 Cells.
International journal of molecular sciences
Zhang Y,Mao H,Li Y,Xiong Y,Liu X,Wang L,Chen Z
Tue Feb 14 00:00:00 EST 2023
Kartogenin-loaded hydrogel promotes intervertebral disc repair via protecting MSCs against reactive oxygen species microenvironment by Nrf2/TXNIP/NLRP3 axis.
Free radical biology & medicine
Wang F,Guo K,Nan L,Wang S,Lu J,Wang Q,Ba Z,Huang Y,Wu D
Tue Aug 01 00:00:00 EDT 2023
Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen B,Wang Y,Cheng J,Peng Y,Zhang Q,Li Z,Zhao L,Deng X,Feng H
Sun Jan 01 00:00:00 EST 2023
Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen B,Wang Y,Cheng J,Peng Y,Zhang Q,Li Z,Zhao L,Deng X,Feng H
Sun Jan 01 00:00:00 EST 2023
Antioxidant Peptides from Monkfish Swim Bladders: Ameliorating NAFLD In Vitro by Suppressing Lipid Accumulation and Oxidative Stress via Regulating AMPK/Nrf2 Pathway.
Marine drugs
Wu MF,Xi QH,Sheng Y,Wang YM,Wang WY,Chi CF,Wang B
Fri Jun 16 00:00:00 EDT 2023
Metformin alleviates ethanol-induced cardiomyocyte injury by activating AKT/Nrf2 signaling in an ErbB2-dependent manner.
Molecular biology reports
Chen Y,Zhu S,Lin Z,Zhang Y,Jin C,He S,Chen X,Zhou X
Sat Apr 01 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Abamectin causes cardiac dysfunction in carp via inhibiting redox equilibrium and resulting in immune inflammatory response and programmed cell death.
Environmental science and pollution research international
Zhao P,Wang Y,Yang Q,Yu G,Ma F,Dong J
Wed Mar 01 00:00:00 EST 2023
Herpes Simplex Virus 1-Induced Ferroptosis Contributes to Viral Encephalitis.
mBio
Xu XQ,Xu T,Ji W,Wang C,Ren Y,Xiong X,Zhou X,Lin SH,Xu Y,Qiu Y
Tue Feb 28 00:00:00 EST 2023
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
International immunopharmacology
Li X,Yu X,He S,Li J
Sat Jul 01 00:00:00 EDT 2023
Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region?
Molecular neurobiology
Lewczuk A,Zablocka B,Beresewicz-Haller M
Wed Mar 01 00:00:00 EST 2023
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway.
Immunopharmacology and immunotoxicology
Zhang H,Lang W,Li S,Xu C,Wang X,Li Y,Zhang Z,Wu T,Feng M
Wed Feb 01 00:00:00 EST 2023
Formononetin ameliorates ferroptosis-associated fibrosis in renal tubular epithelial cells and in mice with chronic kidney disease by suppressing the Smad3/ATF3/SLC7A11 signaling.
Life sciences
Zhu B,Ni Y,Gong Y,Kang X,Guo H,Liu X,Li J,Wang L
Wed Feb 15 00:00:00 EST 2023
Formononetin ameliorates ferroptosis-associated fibrosis in renal tubular epithelial cells and in mice with chronic kidney disease by suppressing the Smad3/ATF3/SLC7A11 signaling.
Life sciences
Zhu B,Ni Y,Gong Y,Kang X,Guo H,Liu X,Li J,Wang L
Wed Feb 15 00:00:00 EST 2023
Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway.
Frontiers in pharmacology
Chen T,Hu Y,Lu L,Zhao Q,Tao X,Ding B,Chen S,Zhu J,Guo X,Lin Z
Tue Mar 28 00:00:00 EDT 2023
Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway.
Frontiers in pharmacology
Chen T,Hu Y,Lu L,Zhao Q,Tao X,Ding B,Chen S,Zhu J,Guo X,Lin Z
Tue Mar 28 00:00:00 EDT 2023
Elabela-APJ axis attenuates cerebral ischemia/reperfusion injury by inhibiting neuronal ferroptosis.
Free radical biology & medicine
Xu P,Kong L,Tao C,Zhu Y,Cheng J,Li W,Shen N,Li R,Zhang C,Wang L,Zhang Y,Wang G,Liu X,Sun W,Hu W
Mon Feb 20 00:00:00 EST 2023
Elabela-APJ axis attenuates cerebral ischemia/reperfusion injury by inhibiting neuronal ferroptosis.
Free radical biology & medicine
Xu P,Kong L,Tao C,Zhu Y,Cheng J,Li W,Shen N,Li R,Zhang C,Wang L,Zhang Y,Wang G,Liu X,Sun W,Hu W
Mon Feb 20 00:00:00 EST 2023
Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress.
Antioxidants (Basel, Switzerland)
Ren W,Wang Z,Cao J,Dong Y,Wang T,Chen Y
Fri Apr 28 00:00:00 EDT 2023
TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway.
Free radical biology & medicine
Cheng Y,Gao Y,Li J,Rui T,Li Q,Chen H,Jia B,Song Y,Gu Z,Wang T,Gao C,Wang Y,Wang Z,Wang F,Tao L,Luo C
Sun Jan 01 00:00:00 EST 2023
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Phytochemistry
Li M,Zhang Y,Han T,Guan L,Fan D,Wu Q,Liu J,Xu Y,Fan Y
Sun Jan 01 00:00:00 EST 2023
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Cell death & disease
Wang G,Qin S,Chen L,Geng H,Zheng Y,Xia C,Yao J,Deng L
Tue Apr 25 00:00:00 EDT 2023
Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth.
Cell & bioscience
Zhao H,Zhang M,Zhang J,Sun Z,Zhang W,Dong W,Cheng C,Yao Y,Li K
Sat May 13 00:00:00 EDT 2023
Iron Saturation Drives Lactoferrin Effects on Oxidative Stress and Neurotoxicity Induced by HIV-1 Tat.
International journal of molecular sciences
Ianiro G,D'Ezio V,Carpinelli L,Casella C,Bonaccorsi di Patti MC,Rosa L,Valenti P,Colasanti M,Musci G,Cutone A,Persichini T
Thu Apr 27 00:00:00 EDT 2023
Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress.
Cardiovascular drugs and therapy
Zhang L,Hu C,Jin B,Bai B,Liao J,Jin L,Wang M,Zhu W,Wu X,Zheng L,Xu X,Jiang Y,Wang Y,He Y
Fri Jan 20 00:00:00 EST 2023
Dietary curcumin supplementation relieves hydrogen peroxide-induced testicular injury by antioxidant and anti-apoptotic effects in roosters.
Theriogenology
Wu H,Ye N,Huang Z,Lei K,Shi F,Wei Q
Wed Feb 01 00:00:00 EST 2023
Cold exposure induces browning of bovine subcutaneous white fat in vivo and in vitro.
Journal of thermal biology
Li T,Bai H,Yang L,Wang H,Wei S,Yan P
Wed Feb 01 00:00:00 EST 2023
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Journal of natural products
Wang W,Liu Y,Xiong L,Sun D,Wang H,Song Z,Li Y,Li H,Chen L
Fri Apr 28 00:00:00 EDT 2023
Donor graft METTL3 gene transfer ameliorates rat liver transplantation ischemia-reperfusion injury by enhancing HO-1 expression in an m6A-dependent manner.
Clinical immunology (Orlando, Fla.)
Xiang S,Wang Y,Lei D,Luo Y,Peng D,Zong K,Liu Y,Huang Z,Mo S,Pu X,Zheng J,Wu Z
Thu Jun 01 00:00:00 EDT 2023
Chrysin protects against cerebral ischemia-reperfusion injury in hippocampus via restraining oxidative stress and transition elements.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Shang J,Jiao J,Yan M,Wang J,Li Q,Shabuerjiang L,Lu Y,Song Q,Bi L,Huang G,Zhang X,Wen Y,Cui Y,Wu K,Li G,Wang P,Liu X
Mon May 01 00:00:00 EDT 2023
Antialcohol and Hepatoprotective Effects of Tamarind Shell Extract on Ethanol-Induced Damage to HepG2 Cells and Animal Models.
Foods (Basel, Switzerland)
Han SC,Huang RP,Zhang QY,Yan CY,Li XY,Li YF,He RR,Li WX
Fri Mar 03 00:00:00 EST 2023
Hydrogen sulfide protects retinal pigment epithelium cells against ferroptosis through the AMPK- and p62-dependent non-canonical NRF2-KEAP1 pathway.
Experimental cell research
Yu M,Wang W,Dang J,Liu B,Xu J,Li J,Liu Y,He L,Ying Y,Cai J,Cheng G,Liu K
Sun Jan 01 00:00:00 EST 2023
Caffeic Acid Phenethyl Ester Suppresses Oxidative Stress and Regulates M1/M2 Microglia Polarization via Sirt6/Nrf2 Pathway to Mitigate Cognitive Impairment in Aged Mice following Anesthesia and Surgery.
Antioxidants (Basel, Switzerland)
Wang Y,Cai Z,Zhan G,Li X,Li S,Wang X,Li S,Luo A
Mon Mar 13 00:00:00 EDT 2023
Molecular alteration of the proteasome contributes to AD-like pathology in the brain of HFD-STZ diabetic rats.
Metabolic brain disease
Gao H,Zhou Y,Jin PS,Wu DG,Wang YN,Zhao X,Zhao B
Wed Mar 01 00:00:00 EST 2023
Molecular alteration of the proteasome contributes to AD-like pathology in the brain of HFD-STZ diabetic rats.
Metabolic brain disease
Gao H,Zhou Y,Jin PS,Wu DG,Wang YN,Zhao X,Zhao B
Wed Mar 01 00:00:00 EST 2023
Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure.
Environmental toxicology and pharmacology
Piell KM,Petri BJ,Head KZ,Wahlang B,Xu R,Zhang X,Pan J,Rai SN,de Silva K,Chariker JH,Rouchka EC,Tan M,Li Y,Cave MC,Klinge CM
Thu Jun 01 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.
Cell death and differentiation
Wang S,Wang T,Zhang X,Cheng S,Chen C,Yang G,Wang F,Wang R,Zhang Q,Yang D,Zhang Y,Liu S,Qin H,Liu Q,Liu H
Sat Jul 01 00:00:00 EDT 2023
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
European journal of nutrition
Wang Y,Chen X,Baker JS,Davison GW,Xu S,Zhou Y,Bao X
Sat Apr 01 00:00:00 EDT 2023
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Psychopharmacology
Liao D,Shangguan D,Wu Y,Chen Y,Liu N,Tang J,Yao D,Shi Y
Mon May 01 00:00:00 EDT 2023
Costunolide alleviates hyperglycaemia-induced diabetic cardiomyopathy via inhibiting inflammatory responses and oxidative stress.
Journal of cellular and molecular medicine
Jin B,Chen Y,Wang J,Chen Y,Zhang M,Huang J,Wang Y
Wed Mar 01 00:00:00 EST 2023
Mechanisms underlying citrinin-induced toxicity via oxidative stress and apoptosis-mediated by mitochondrial-dependent pathway in SH-SY5Y cells.
Drug and chemical toxicology
Abudayyak M,Karaman EF,Ozden S
Wed Nov 01 00:00:00 EDT 2023
Aloperine alleviates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome activation.
International immunopharmacology
Zeng J,Liu J,Huang JH,Fu SP,Wang XY,Xi C,Cui YR,Qu F
Sat Jul 01 00:00:00 EDT 2023
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu Y,Mi Y,Wang Y,Meng Q,Xu L,Liu Y,Zhou D,Wang Y,Liang D,Li W,Li N,Hou Y
Mon May 01 00:00:00 EDT 2023
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu Y,Mi Y,Wang Y,Meng Q,Xu L,Liu Y,Zhou D,Wang Y,Liang D,Li W,Li N,Hou Y
Mon May 01 00:00:00 EDT 2023
Inhibition of p62 and/or NFE2L2 induced autophagy impaires esophageal squamous cell cancer metastasis by reversing EMT.
Gene
Chen X,Yu L,Zhou J,Ren J,Wang S,Tan Y,Ding Y
Thu Mar 30 00:00:00 EDT 2023
Inhibition of p62 and/or NFE2L2 induced autophagy impaires esophageal squamous cell cancer metastasis by reversing EMT.
Gene
Chen X,Yu L,Zhou J,Ren J,Wang S,Tan Y,Ding Y
Thu Mar 30 00:00:00 EDT 2023
Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy.
Cell & bioscience
Xia Q,Li Y,Xu W,Wu C,Zheng H,Liu L,Dong L
Tue Feb 21 00:00:00 EST 2023
Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy.
Cell & bioscience
Xia Q,Li Y,Xu W,Wu C,Zheng H,Liu L,Dong L
Tue Feb 21 00:00:00 EST 2023
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hu Y,Yan Z,He Y,Li Y,Li M,Li Y,Zhang D,Zhao Y,Ommati MM,Wang J,Huo M,Wang J
Sat Apr 01 00:00:00 EDT 2023
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hu Y,Yan Z,He Y,Li Y,Li M,Li Y,Zhang D,Zhao Y,Ommati MM,Wang J,Huo M,Wang J
Sat Apr 01 00:00:00 EDT 2023
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Journal of ethnopharmacology
Wu S,Tian C,Tu Z,Guo J,Xu F,Qin W,Chang H,Wang Z,Hu T,Sun X,Ning H,Li Y,Gou W,Hou W
Sat Jul 15 00:00:00 EDT 2023
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Neurochemical research
Shen M,Zheng Y,Li G,Chen Y,Huang L,Wu J,Hong C
Wed Feb 01 00:00:00 EST 2023
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Neurochemical research
Shen M,Zheng Y,Li G,Chen Y,Huang L,Wu J,Hong C
Wed Feb 01 00:00:00 EST 2023
Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes.
Toxicology
Boran T,Zengin OS,Seker Z,Akyildiz AG,Oztas E,Özhan G
Mon May 01 00:00:00 EDT 2023
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Drug delivery and translational research
Xiang X,Chen J,Jiang T,Yan C,Kang Y,Zhang M,Xiang K,Guo J,Jiang G,Wang C,Yang X,Chen Z
Fri Sep 01 00:00:00 EDT 2023
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
Nature cell biology
Romani P,Nirchio N,Arboit M,Barbieri V,Tosi A,Michielin F,Shibuya S,Benoist T,Wu D,Hindmarch CCT,Giomo M,Urciuolo A,Giamogante F,Roveri A,Chakravarty P,Montagner M,Calì T,Elvassore N,Archer SL,De Coppi P,Rosato A,Martello G,Dupont S
Tue Feb 01 00:00:00 EST 2022
TRPV1 Modulator Ameliorates Alzheimer-Like Amyloid-β Neuropathology via Akt/Gsk3β-Mediated Nrf2 Activation in the Neuro-2a/APP Cell Model.
Oxidative medicine and cellular longevity
Wang X,Bian Y,Wong CTT,Lu JH,Lee SM
Mon Dec 12 00:00:00 EST 2022
TRPV1 Modulator Ameliorates Alzheimer-Like Amyloid-β Neuropathology via Akt/Gsk3β-Mediated Nrf2 Activation in the Neuro-2a/APP Cell Model.
Oxidative medicine and cellular longevity
Wang X,Bian Y,Wong CTT,Lu JH,Lee SM
Mon Dec 12 00:00:00 EST 2022
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Arthritis research & therapy
Peng P,Wang D,Xu X,Wang D,Gao B,Wang H,Jia H,Shang Q,Zheng C,Gao C,Mao J,Luo Z,Yang L,Hu X
Wed Aug 03 00:00:00 EDT 2022
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Arthritis research & therapy
Peng P,Wang D,Xu X,Wang D,Gao B,Wang H,Jia H,Shang Q,Zheng C,Gao C,Mao J,Luo Z,Yang L,Hu X
Wed Aug 03 00:00:00 EDT 2022
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Arthritis research & therapy
Peng P,Wang D,Xu X,Wang D,Gao B,Wang H,Jia H,Shang Q,Zheng C,Gao C,Mao J,Luo Z,Yang L,Hu X
Wed Aug 03 00:00:00 EDT 2022
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration.
Arthritis research & therapy
Peng P,Wang D,Xu X,Wang D,Gao B,Wang H,Jia H,Shang Q,Zheng C,Gao C,Mao J,Luo Z,Yang L,Hu X
Wed Aug 03 00:00:00 EDT 2022
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Sun W,Xie W,Huang D,Cui Y,Yue J,He Q,Jiang L,Xiong J,Sun W,Yi Q
Tue Nov 01 00:00:00 EDT 2022
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Sun W,Xie W,Huang D,Cui Y,Yue J,He Q,Jiang L,Xiong J,Sun W,Yi Q
Tue Nov 01 00:00:00 EDT 2022
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Sun W,Xie W,Huang D,Cui Y,Yue J,He Q,Jiang L,Xiong J,Sun W,Yi Q
Tue Nov 01 00:00:00 EDT 2022
Hepatic Lipid Accumulation and Dysregulation Associate with Enhanced Reactive Oxygen Species and Pro-Inflammatory Cytokine in Low-Birth-Weight Goats.
Animals : an open access journal from MDPI
Liu T,Li R,Luo N,Lou P,Limesand SW,Yang Y,Zhao Y,Chen X
Fri Mar 18 00:00:00 EDT 2022
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Free radical biology & medicine
Li XT,Song JW,Zhang ZZ,Zhang MW,Liang LR,Miao R,Liu Y,Chen YH,Liu XY,Zhong JC
Sun Nov 20 00:00:00 EST 2022
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Free radical biology & medicine
Li XT,Song JW,Zhang ZZ,Zhang MW,Liang LR,Miao R,Liu Y,Chen YH,Liu XY,Zhong JC
Sun Nov 20 00:00:00 EST 2022
Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis.
Cells
Zhang Z,Ji C,Wang YN,Liu S,Wang M,Xu X,Zhang D
Wed Aug 17 00:00:00 EDT 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 EDT 2022
Dehydroeburicoic Acid, a Dual Inhibitor against Oxidative Stress in Alcoholic Liver Disease.
Pharmaceuticals (Basel, Switzerland)
Cheng S,Kuang Y,Li G,Wu J,Ko CN,Wang W,Ma DL,Ye M,Leung CH
Thu Dec 22 00:00:00 EST 2022
Dehydroeburicoic Acid, a Dual Inhibitor against Oxidative Stress in Alcoholic Liver Disease.
Pharmaceuticals (Basel, Switzerland)
Cheng S,Kuang Y,Li G,Wu J,Ko CN,Wang W,Ma DL,Ye M,Leung CH
Thu Dec 22 00:00:00 EST 2022
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Antioxidants (Basel, Switzerland)
Xiong L,Wu H,Zhong T,Luo F,Li Q,Li M,Fan Y
Wed Oct 12 00:00:00 EDT 2022
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Oxidative medicine and cellular longevity
Huang Q,Peng M,Gu Y,Wu J,Zhan Y,Deng Z,Chen S,Yang R,Chen J,Xie J
Fri Dec 30 00:00:00 EST 2022
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Journal of agricultural and food chemistry
Wang Q,Wang C,Tian W,Qiu Z,Song M,Cao Y,Xiao J
Wed Feb 23 00:00:00 EST 2022
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Ecotoxicology and environmental safety
Liu F,Wang Y,Chen L,Bello BK,Zhang T,Yang H,Li X,Pan E,Feng H,Dong J
Sat Oct 01 00:00:00 EDT 2022
Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment.
Acta pharmacologica Sinica
Wang L,Zhao L,Gong FL,Sun C,Du DD,Yang XX,Guo XL
Wed Jun 01 00:00:00 EDT 2022
Effects of Inorganic and Organic Manganese Supplementation on Growth Performance, Tibia Development, and Oxidative Stress in Broiler Chickens.
Biological trace element research
Xia WH,Tang L,Wang ZY,Wang L
Sat Oct 01 00:00:00 EDT 2022
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Biology
Li B,Wang C,Lu P,Ji Y,Wang X,Liu C,Lu X,Xu X,Wang X
Fri Sep 23 00:00:00 EDT 2022
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes.
Archives of toxicology
Xiong L,Huang J,Wang S,Yuan Q,Yang D,Zheng Z,Wu Y,Wu C,Gao Y,Zou L,Hu G
Tue Mar 01 00:00:00 EST 2022
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes.
Archives of toxicology
Xiong L,Huang J,Wang S,Yuan Q,Yang D,Zheng Z,Wu Y,Wu C,Gao Y,Zou L,Hu G
Tue Mar 01 00:00:00 EST 2022
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Drug design, development and therapy
Xiao S,Zhou Y,Wang Q,Yang D
Thu Jan 05 00:00:00 EST 2023
Melatonin Nuclear Receptors Mediate Green-and-Blue-Monochromatic-Light-Combinations-Inhibited B Lymphocyte Apoptosis in the Bursa of Chickens via Reducing Oxidative Stress and Nfκb Expression.
Antioxidants (Basel, Switzerland)
Zhang Y,Wang Z,Dong Y,Cao J,Chen Y
Fri Apr 08 00:00:00 EDT 2022
Oxidative injury induced by drinking water disinfection by-products dibromoacetonitrile and dichloroacetonitrile in mouse hippocampal neuronal cells: The protective effect of N-acetyl-L-cysteine.
Toxicology letters
Li F,Zhou J,Zhu X,Lu R,Ye Y,Wang S,Xing G,Shen H
Fri Jul 15 00:00:00 EDT 2022
Oxidative injury induced by drinking water disinfection by-products dibromoacetonitrile and dichloroacetonitrile in mouse hippocampal neuronal cells: The protective effect of N-acetyl-L-cysteine.
Toxicology letters
Li F,Zhou J,Zhu X,Lu R,Ye Y,Wang S,Xing G,Shen H
Fri Jul 15 00:00:00 EDT 2022
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway.
Journal of agricultural and food chemistry
Fan Y,Lu J,Yu Z,Qu X,Guan S
Wed Sep 07 00:00:00 EDT 2022
Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway.
International immunopharmacology
Yao TT,Zhang Y,He RL,Lv X,He YJ,Li MY,Han YY,Long LZ,Jiang GL,Cheng XY,Hu GY,Li QB,Tao LJ,Meng J
Thu Dec 01 00:00:00 EST 2022
Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway.
International immunopharmacology
Yao TT,Zhang Y,He RL,Lv X,He YJ,Li MY,Han YY,Long LZ,Jiang GL,Cheng XY,Hu GY,Li QB,Tao LJ,Meng J
Thu Dec 01 00:00:00 EST 2022
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Nutrients
Shi JZ,Zheng XM,Zhou YF,Yun LY,Luo DM,Hao JJ,Liu PF,Zhang WK,Xu JK,Yan Y,Xie XM,He YY,Pang XB
Wed Aug 03 00:00:00 EDT 2022
Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen J,Zhang J,Chen T,Bao S,Li J,Wei H,Hu X,Liang Y,Liu F,Yan S
Tue Nov 01 00:00:00 EDT 2022
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Oxidative medicine and cellular longevity
Zhao S,Huang M,Yan L,Zhang H,Shi C,Liu J,Zhao S,Liu H,Wang B
Tue Aug 02 00:00:00 EDT 2022
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Oxidative medicine and cellular longevity
Zhao S,Huang M,Yan L,Zhang H,Shi C,Liu J,Zhao S,Liu H,Wang B
Tue Aug 02 00:00:00 EDT 2022
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Phytotherapy research : PTR
Cheng L,Shi L,He C,Wang C,Lv Y,Li H,An Y,Dai H,Duan Y,Zhang H,Huang Y,Fu W,Meng Y,Zhao B
Wed Jun 01 00:00:00 EDT 2022
Naringin Relieves Diabetic Cardiac Autonomic Neuropathy Mediated by P2Y14 Receptor in Superior Cervical Ganglion.
Frontiers in pharmacology
Tang G,Pi L,Guo H,Hu Z,Zhou C,Hu Q,Peng H,Xiao Z,Zhang Z,Wang M,Peng T,Huang J,Liang S,Li G
Sat Jul 16 00:00:00 EDT 2022
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
Molecules (Basel, Switzerland)
Luo JF,Zhou H,Lio CK
Thu Sep 22 00:00:00 EDT 2022
AGuIX nanoparticles enhance ionizing radiation-induced ferroptosis on tumor cells by targeting the NRF2-GPX4 signaling pathway.
Journal of nanobiotechnology
Sun H,Cai H,Xu C,Zhai H,Lux F,Xie Y,Feng L,Du L,Liu Y,Sun X,Wang Q,Song H,He N,Zhang M,Ji K,Wang J,Gu Y,Leduc G,Doussineau T,Wang Y,Liu Q,Tillement O
Fri Oct 14 00:00:00 EDT 2022
2-undecanone protects against fine particles-induced heart inflammation via modulating Nrf2/HO-1 and NF-κB pathways.
Environmental toxicology
Jiao Y,Wang S,Jiang L,Sun X,Li J,Liu X,Yao X,Zhang C,Wang N,Deng H,Yang G
Fri Jul 01 00:00:00 EDT 2022
Immune response gene 1 deficiency impairs Nrf2 activation and aggravates liver fibrosis in mice.
Biochemical and biophysical research communications
Fan K,Zan X,Zhi Y,Yang Y,Hu K,Zhang X,Zhang X,Zhao S,Chen K,Gong X,Tian R,Zhang L
Sat Jun 04 00:00:00 EDT 2022
Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes.
Evidence-based complementary and alternative medicine : eCAM
Hou J,Wang L,Wang C,Ma R,Wang Z,Xiao H,Zeng D,Ling L,Wang Y
Sat Oct 22 00:00:00 EDT 2022
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Translational neuroscience
Huang L,Han Y,Zhou Q,Sun Z,Yan J
Sat Jan 01 00:00:00 EST 2022
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Small (Weinheim an der Bergstrasse, Germany)
Guan G,Zhang Q,Jiang Z,Liu J,Wan J,Jin P,Lv Q
Thu Dec 01 00:00:00 EST 2022
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Small (Weinheim an der Bergstrasse, Germany)
Guan G,Zhang Q,Jiang Z,Liu J,Wan J,Jin P,Lv Q
Thu Dec 01 00:00:00 EST 2022
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sun Y,Teng Y,Wang L,Zhang Z,Chen C,Wang Y,Zhang X,Xiang P,Song X,Lu J,Li N,Gao L,Liang X,Xia Y,Wu Z,Ma C
Sun May 01 00:00:00 EDT 2022
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sun Y,Teng Y,Wang L,Zhang Z,Chen C,Wang Y,Zhang X,Xiang P,Song X,Lu J,Li N,Gao L,Liang X,Xia Y,Wu Z,Ma C
Sun May 01 00:00:00 EDT 2022
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Frontiers in molecular biosciences
Zou P,Zhang X,Zhang R,Chai X,Zhao Y,Li E,Zhang Q,Yan R,Yang J,Liao B
Sat Apr 09 00:00:00 EDT 2022
Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
Biochemical pharmacology
Yang W,Tao K,Zhang P,Chen X,Sun X,Li R
Sat Jan 01 00:00:00 EST 2022
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Frontiers in oncology
Liu H,Zhao L,Wang M,Yang K,Jin Z,Zhao C,Shi G
Sat Apr 09 00:00:00 EDT 2022
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Frontiers in oncology
Liu H,Zhao L,Wang M,Yang K,Jin Z,Zhao C,Shi G
Sat Apr 09 00:00:00 EDT 2022
Anti-inflammatory and Antioxidant Effects of Pyrroloquinoline Quinone in L-NAME-Induced Preeclampsia-Like Rat Model.
Reproductive sciences (Thousand Oaks, Calif.)
Wang H,Li M,Chen P,Shi X
Tue Feb 01 00:00:00 EST 2022
Ferroptosis contributes to hypoxic-ischemic brain injury in neonatal rats: Role of the SIRT1/Nrf2/GPx4 signaling pathway.
CNS neuroscience & therapeutics
Li C,Wu Z,Xue H,Gao Q,Zhang Y,Wang C,Zhao P
Thu Dec 01 00:00:00 EST 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
PLK-1 Interacting Checkpoint Helicase, PICH, Mediates Cellular Oxidative Stress Response.
Epigenomes
Dutta A,Das A,Bisht D,Arya V,Muthuswami R
Tue Oct 18 00:00:00 EDT 2022
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway.
Journal of neuroinflammation
Dang R,Wang M,Li X,Wang H,Liu L,Wu Q,Zhao J,Ji P,Zhong L,Licinio J,Xie P
Mon Feb 07 00:00:00 EST 2022
The Nrf2 inhibitor brusatol synergistically enhances the cytotoxic effect of lapatinib in HER2-positive cancers.
Heliyon
Tian Z,Yang Y,Wu H,Chen Y,Jia H,Zhu L,He R,Jin Y,Zhou B,Ge C,Sun Y,Yang Y
Mon Aug 01 00:00:00 EDT 2022
Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.
Frontiers in physiology
Qin X,Liu B,Gao F,Hu Y,Chen Z,Xu J,Zhang X
Sat Apr 02 00:00:00 EDT 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 EDT 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 EDT 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 EDT 2022
6-Gingerol exerts a protective effect against hypoxic injury through the p38/Nrf2/HO-1 and p38/NF-κB pathway in H9c2 cells.
The Journal of nutritional biochemistry
Han X,Liu P,Zheng B,Zhang M,Zhang Y,Xue Y,Liu C,Chu X,Wang X,Sun S,Chu L
Wed Jun 01 00:00:00 EDT 2022
ACSL4-dependent ferroptosis does not represent a tumor-suppressive mechanism but ACSL4 rather promotes liver cancer progression.
Cell death & disease
Grube J,Woitok MM,Mohs A,Erschfeld S,Lynen C,Trautwein C,Otto T
Sat Aug 13 00:00:00 EDT 2022
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Journal of nanobiotechnology
Jin Y,Zhang Q,Qin X,Liu Z,Li Z,Zhong X,Xia L,He J,Fang B
Thu Nov 03 00:00:00 EDT 2022
Klotho alleviates NLRP3 inflammasome-mediated neuroinflammation in a temporal lobe epilepsy rat model by activating the Nrf2 signaling pathway.
Epilepsy & behavior : E&B
Xiang T,Luo X,Ye L,Huang H,Wu Y
Tue Mar 01 00:00:00 EST 2022
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Aug 06 00:00:00 EDT 2022
Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance.
Acta pharmaceutica Sinica. B
Wang H,Wang Q,Cai G,Duan Z,Nugent Z,Huang J,Zheng J,Borowsky AD,Li JJ,Liu P,Kung HJ,Murphy L,Chen HW,Wang J
Fri Apr 01 00:00:00 EDT 2022
Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance.
Acta pharmaceutica Sinica. B
Wang H,Wang Q,Cai G,Duan Z,Nugent Z,Huang J,Zheng J,Borowsky AD,Li JJ,Liu P,Kung HJ,Murphy L,Chen HW,Wang J
Fri Apr 01 00:00:00 EDT 2022
Hinokitiol functions as a ferroptosis inhibitor to confer neuroprotection.
Free radical biology & medicine
Xi J,Zhang Z,Wang Z,Wu Q,He Y,Xu Y,Ding Z,Zhao H,Da H,Zhang F,Zhao H,Fang J
Thu Sep 01 00:00:00 EDT 2022
Protective role of TLR9-induced macrophage/microglia phagocytosis after experimental intracerebral hemorrhage in mice.
CNS neuroscience & therapeutics
Wei J,Dai S,Pu C,Luo P,Yang Y,Jiang X,Li X,Lin W,Fei Z
Tue Nov 01 00:00:00 EDT 2022
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Frontiers in physiology
Li S,Dong S,Xu Q,Shi B,Li L,Zhang W,Zhu J,Cheng Y,Zhang G,Zhong M
Sat Apr 02 00:00:00 EDT 2022
Pyrogallol enhances therapeutic effect of human umbilical cord mesenchymal stem cells against LPS-mediated inflammation and lung injury via activation of Nrf2/HO-1 signaling.
Free radical biology & medicine
Zhang Y,Yang S,Qiu Z,Huang L,Huang L,Liang Y,Liu X,Wang M,Zhou B
Sat Oct 01 00:00:00 EDT 2022
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Journal of cellular and molecular medicine
Li M,Wang C,Yu Z,Lan Q,Xu S,Ye Z,Li R,Ying L,Zhang X,Zhou Z
Mon Aug 01 00:00:00 EDT 2022
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R-/-) Mice.
BioMed research international
Li W,Zhang H,Zhang L,Zhang T,Ding H
Tue Jul 19 00:00:00 EDT 2022
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R-/-) Mice.
BioMed research international
Li W,Zhang H,Zhang L,Zhang T,Ding H
Tue Jul 19 00:00:00 EDT 2022
Exposure to Bisphenol A Caused Hepatoxicity and Intestinal Flora Disorder in Rats.
International journal of molecular sciences
Liu R,Liu B,Tian L,Jiang X,Li X,Cai D,Sun J,Bai W,Jin Y
Thu Jul 21 00:00:00 EDT 2022
Protective effect of resveratrol against hydrogen peroxide-induced oxidative stress in bovine skeletal muscle cells.
Meat science
Zhang X,Liu X,Wan F,You W,Tan X,Sheng Q,Li C,Hu Z,Liu G,Zhao H
Tue Mar 01 00:00:00 EST 2022
Protective effect of resveratrol against hydrogen peroxide-induced oxidative stress in bovine skeletal muscle cells.
Meat science
Zhang X,Liu X,Wan F,You W,Tan X,Sheng Q,Li C,Hu Z,Liu G,Zhao H
Tue Mar 01 00:00:00 EST 2022
Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2'-Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester.
Oxidative medicine and cellular longevity
Guan D,Zhou W,Wei H,Wang T,Zheng K,Yang C,Feng R,Xu R,Fu Y,Li C,Li Y,Li C
Thu Mar 24 00:00:00 EDT 2022
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway.
Environmental science and pollution research international
Ma Y,Li S,Tang S,Ye S,Liang N,Liang Y,Xiao F
Fri Jul 01 00:00:00 EDT 2022
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway.
Environmental science and pollution research international
Ma Y,Li S,Tang S,Ye S,Liang N,Liang Y,Xiao F
Fri Jul 01 00:00:00 EDT 2022
The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2.
Cells
Nguyen V,Zhang Y,Gao C,Cao X,Tian Y,Carver W,Kiaris H,Cui T,Tan W
Tue Jun 14 00:00:00 EDT 2022
Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling.
European journal of medicinal chemistry
Lu Q,Gouda NA,Quan G,Nada H,Elkamhawy A,Lee D,Lee CH,Cho J,Lee K
Tue Nov 15 00:00:00 EST 2022
Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling.
European journal of medicinal chemistry
Lu Q,Gouda NA,Quan G,Nada H,Elkamhawy A,Lee D,Lee CH,Cho J,Lee K
Tue Nov 15 00:00:00 EST 2022
Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo.
Cell death & disease
Wang G,Wang Y,Yang Q,Xu C,Zheng Y,Wang L,Wu J,Zeng M,Luo M
Mon Jan 10 00:00:00 EST 2022
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Molecular carcinogenesis
Fang J,Ma Y,Li Y,Li J,Zhang X,Han X,Ma S,Guan F
Tue Nov 01 00:00:00 EDT 2022
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Journal of oncology
Nie XH,Qiu S,Xing Y,Xu J,Lu B,Zhao SF,Li YT,Su ZZ
Wed Jan 11 00:00:00 EST 2023
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
Journal of the science of food and agriculture
Zhao W,Peng D,Li W,Chen S,Liu B,Huang P,Wu J,Du B,Li P
Thu Dec 01 00:00:00 EST 2022
Novel Probiotic Lactic Acid Bacteria Were Identified from Healthy Infant Feces and Exhibited Anti-Inflammatory Capacities.
Antioxidants (Basel, Switzerland)
Li B,Pan LL,Sun J
Fri Jun 24 00:00:00 EDT 2022
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
International immunopharmacology
He J,Liu L,Liu X,Chen H,Liu K,Huang N,Wang Y
Thu Dec 01 00:00:00 EST 2022
Tripeptide Leu-Pro-Phe from Corn Protein Hydrolysates Attenuates Hyperglycemia-Induced Neural Tube Defect in Chicken Embryos.
Oxidative medicine and cellular longevity
Yan CY,Sun J,Yu GY,Liu JH,Huang RP,Han SC,Zhang QY,Li XM,Yan JG,Kurihara H,Li WX,Li YF,He RR
Fri Sep 09 00:00:00 EDT 2022
Tripeptide Leu-Pro-Phe from Corn Protein Hydrolysates Attenuates Hyperglycemia-Induced Neural Tube Defect in Chicken Embryos.
Oxidative medicine and cellular longevity
Yan CY,Sun J,Yu GY,Liu JH,Huang RP,Han SC,Zhang QY,Li XM,Yan JG,Kurihara H,Li WX,Li YF,He RR
Fri Sep 09 00:00:00 EDT 2022
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H2O2-induced BV-2 microglial cells injury.
Bioorganic chemistry
Wang Y,Zhu M,Liang J,Zhang N,Sun D,Li H,Chen L
Tue Nov 01 00:00:00 EDT 2022
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang J,Zhang L,Cao H,Shi X,Zhang X,Gao Z,Ikeda K,Yan T,Jia Y,Xu F
Sun May 01 00:00:00 EDT 2022
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Journal of animal science
Yu G,Ji S,Yun Y,Cheng K,Zhang H,Jia P,Wang T,Zhang L
Fri Jul 01 00:00:00 EDT 2022
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
Acta pharmacologica Sinica
Ye C,Geng Z,Zhang LL,Zheng F,Zhou YB,Zhu GQ,Xiong XQ
Sat Oct 01 00:00:00 EDT 2022
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang B,Wan S,Liu H,Qiu Q,Chen H,Chen Z,Wang L,Liu X
Wed Oct 26 00:00:00 EDT 2022
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen Y,Liu Y,Huang Q,Liu R,Liu J,Zhang F,Liu S,Jiang Y
Sat Jan 01 00:00:00 EST 2022
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen Y,Liu Y,Huang Q,Liu R,Liu J,Zhang F,Liu S,Jiang Y
Sat Jan 01 00:00:00 EST 2022
An auto-photoacoustic melanin-based drug delivery nano-platform for self-monitoring of acute kidney injury therapy via a triple-collaborative strategy.
Acta biomaterialia
Zhao X,Sun J,Dong J,Guo C,Cai W,Han J,Shen H,Lv S,Zhang R
Fri Jul 15 00:00:00 EDT 2022
Effects of folic acid on oxidative damage of kidney in lead-exposed rats.
Frontiers in nutrition
Li N,Wen L,Yu Z,Li T,Wang T,Qiao M,Song L,Huang X
Sat Dec 03 00:00:00 EST 2022
Therapeutic effects of total saikosaponins from Radix bupleuri against Alzheimer's disease.
Frontiers in pharmacology
Li J,Zou B,Cheng XY,Yang XH,Li J,Zhao CH,Ma RX,Tian JX,Yao Y
Tue Aug 09 00:00:00 EDT 2022
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Andrologia
Fu W,Chen S,Zhang Z,Chen Y,You X,Li Q
Sat Oct 01 00:00:00 EDT 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
Photothermal therapy with regulated Nrf2/NF-κB signaling pathway for treating bacteria-induced periodontitis.
Bioactive materials
Tian Y,Li Y,Liu J,Lin Y,Jiao J,Chen B,Wang W,Wu S,Li C
Tue Mar 01 00:00:00 EST 2022
Protective Effect of Lycium ruthenicum Polyphenols on Oxidative Stress against Acrylamide Induced Liver Injury in Rats.
Molecules (Basel, Switzerland)
Gao H,Xue Y,Wu L,Huo J,Pang Y,Chen J,Gao Q
Sat Jun 25 00:00:00 EDT 2022
Sinomenine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress, inflammation and apoptosis in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Fan H,Tu T,Zhang X,Yang Q,Liu G,Zhang T,Bao Y,Lu Y,Dong Z,Dong J,Zhao P
Sat Jan 01 00:00:00 EST 2022
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
ACS applied materials & interfaces
Qi S,Luo R,Han X,Nie W,Ye N,Fu C,Gao F
Wed Nov 16 00:00:00 EST 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation.
Cells
Ueda E,Ohta T,Konno A,Hirai H,Kurauchi Y,Katsuki H,Seki T
Tue Apr 05 00:00:00 EDT 2022
Development of a New DHFR-Based Destabilizing Domain with Enhanced Basal Turnover and Applicability in Mammalian Systems.
ACS chemical biology
Nakahara E,Mullapudi V,Collier GE,Joachimiak LA,Hulleman JD
Fri Oct 21 00:00:00 EDT 2022
Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.
Neurotoxicity research
Wu P,Dong Y,Chen J,Guan T,Cao B,Zhang Y,Qi Y,Guan Z,Wang Y
Tue Feb 01 00:00:00 EST 2022
The dual role of p62 in ferroptosis of glioblastoma according to p53 status.
Cell & bioscience
Yuan F,Sun Q,Zhang S,Ye L,Xu Y,Deng G,Xu Z,Zhang S,Liu B,Chen Q
Fri Feb 25 00:00:00 EST 2022
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Phytotherapy research : PTR
Wu XY,Wang T,Hu HX,Zhang K,Zhao Y,Zhao BB,Lou HX,Wang XN,Shen T
Fri Apr 01 00:00:00 EDT 2022
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Phytotherapy research : PTR
Wu XY,Wang T,Hu HX,Zhang K,Zhao Y,Zhao BB,Lou HX,Wang XN,Shen T
Fri Apr 01 00:00:00 EDT 2022
Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke.
iScience
Liu J,Shen D,Wei C,Wu W,Luo Z,Hu L,Xiao Z,Hu T,Sun Q,Wang X,Ding Y,Liu M,Pang M,Gai K,Ma Y,Tian Y,Yu Y,Wang P,Guan Y,Xu M,Yang F,Li Q
Thu Dec 22 00:00:00 EST 2022
Collagen peptides from Acaudina molpadioides prevent CCl4 -induced liver injury via Keap1/Nrf2-ARE, PI3K/AKT, and MAPKs pathways.
Journal of food science
Li J,Li Y,Lin S,Zhao W,Chen Y,Jin H
Sun May 01 00:00:00 EDT 2022
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
BioMed research international
Shi H,Yan Y,Yang H,Pu P,Tang H
Wed Sep 07 00:00:00 EDT 2022
Total flavonoids of Inula japonica alleviated the inflammatory response and oxidative stress in LPS-induced acute lung injury via inhibiting the sEH activity: Insights from lipid metabolomics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Huo XK,Sun CP,Ma XC,Xiao HT
Thu Dec 01 00:00:00 EST 2022
Chaihujialonggumulitang shows psycho-cardiology therapeutic effect on acute myocardial infarction with comorbid anxiety by the activation of Nrf2/HO-1 pathway and suppression of oxidative stress and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Shi J,Hou J,Sun Y,Jia Z,Zhou Y,Wang C,Zhao H
Thu Sep 01 00:00:00 EDT 2022
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease.
International journal of molecular medicine
Lin F,Xu L,Yuan R,Han S,Xie J,Jiang K,Li B,Yu W,Rao T,Zhou X,Cheng F
Tue Mar 01 00:00:00 EST 2022
Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling.
Brain research bulletin
Hua D,Luo A,Wu Z,Huang C,Li S,Xu X,Xu J,Yang C,Wang D,Liu C
Fri Apr 01 00:00:00 EDT 2022
Realgar-induced nephrotoxicity via ferroptosis in mice.
Journal of applied toxicology : JAT
Zhang S,Cao S,Zhou H,Li L,Hu Q,Mao X,Ji S
Tue Nov 01 00:00:00 EDT 2022
Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice.
International journal of molecular sciences
Ding X,Chen Y,Zhou L,Wu R,Jian T,Lyu H,Liu Y,Chen J
Sat Jul 02 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.
Free radical biology & medicine
Zhang Z,Tang J,Song J,Xie M,Liu Y,Dong Z,Liu X,Li X,Zhang M,Chen Y,Shi H,Zhong J
Tue Mar 01 00:00:00 EST 2022
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
European journal of pharmacology
Fan H,Cui J,Liu F,Zhang W,Yang H,He N,Dong Z,Dong J
Sat Oct 15 00:00:00 EDT 2022
Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy.
Cellular and molecular life sciences : CMLS
Liu P,Lin C,Liu Z,Zhu C,Lin Z,Xu D,Chen J,Huang Q,Li CY,Hou L,Pan JA,Liu X
Wed Jun 08 00:00:00 EDT 2022
Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy.
Cellular and molecular life sciences : CMLS
Liu P,Lin C,Liu Z,Zhu C,Lin Z,Xu D,Chen J,Huang Q,Li CY,Hou L,Pan JA,Liu X
Wed Jun 08 00:00:00 EDT 2022
Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the Nrf2 pathway.
Aging
Shan Y,Yang G,Lu Q,Hu X,Qi D,Zhou Y,Xiao Y,Cao L,Tian F,Pan Q
Thu Mar 10 00:00:00 EST 2022
Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the Nrf2 pathway.
Aging
Shan Y,Yang G,Lu Q,Hu X,Qi D,Zhou Y,Xiao Y,Cao L,Tian F,Pan Q
Thu Mar 10 00:00:00 EST 2022
The beneficial effects of traditional Chinese medicine on antioxidative status and inflammatory cytokines expression in the liver of piglets.
Frontiers in veterinary science
Wang X,Wang Y,Mao Y,Hu A,Xu T,Yang Y,Wang F,Zhou G,Guo X,Cao H,Yang F
Fri Nov 25 00:00:00 EST 2022
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zeng Z,Huang H,Zhang J,Liu Y,Zhong W,Chen W,Lu Y,Qiao Y,Zhao H,Meng X,Zou F,Cai S,Dong H
Wed Jun 01 00:00:00 EDT 2022
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zeng Z,Huang H,Zhang J,Liu Y,Zhong W,Chen W,Lu Y,Qiao Y,Zhao H,Meng X,Zou F,Cai S,Dong H
Wed Jun 01 00:00:00 EDT 2022
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zeng Z,Huang H,Zhang J,Liu Y,Zhong W,Chen W,Lu Y,Qiao Y,Zhao H,Meng X,Zou F,Cai S,Dong H
Wed Jun 01 00:00:00 EDT 2022
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zeng Z,Huang H,Zhang J,Liu Y,Zhong W,Chen W,Lu Y,Qiao Y,Zhao H,Meng X,Zou F,Cai S,Dong H
Wed Jun 01 00:00:00 EDT 2022
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Chemical biology & drug design
Zhu W,Tang H,Cao L,Zhang J,Li J,Ma D,Guo C
Fri Jul 01 00:00:00 EDT 2022
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway.
Frontiers in pharmacology
Guo Z,Lin J,Sun K,Guo J,Yao X,Wang G,Hou L,Xu J,Guo J,Guo F
Tue May 30 00:00:00 EDT 2023
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Chinese medicine
Huang W,Wen F,Gu P,Liu J,Xia Y,Li Y,Zhou J,Song S,Ruan S,Gu S,Chen X,Shu P
Tue Aug 09 00:00:00 EDT 2022
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Chinese medicine
Huang W,Wen F,Gu P,Liu J,Xia Y,Li Y,Zhou J,Song S,Ruan S,Gu S,Chen X,Shu P
Tue Aug 09 00:00:00 EDT 2022
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
Free radical biology & medicine
Peng X,Su S,Zeng J,Xie K,Yang X,Xian G,Xiao Z,Zhu P,Zheng S,Xu D,Zeng Q
Mon Aug 01 00:00:00 EDT 2022
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Metabolic brain disease
Ren X,Yu J,Guo L,Zhang Z
Sat Oct 01 00:00:00 EDT 2022
m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin.
Autophagy
Liang D,Lin WJ,Ren M,Qiu J,Yang C,Wang X,Li N,Zeng T,Sun K,You L,Yan L,Wang W
Wed Jun 01 00:00:00 EDT 2022
Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.
Journal of medicinal chemistry
Dai Z,An LY,Chen XY,Yang F,Zhao N,Li CC,Ren R,Li BY,Tao WY,Li P,Jiang C,Yan F,Jiang ZY,You QD,Di B,Xu LL
Thu Mar 24 00:00:00 EDT 2022
GSTM3 deficiency impedes DNA mismatch repair to promote gastric tumorigenesis via CAND1/NRF2-KEAP1 signaling.
Cancer letters
Chen T,Jinlin D,Wang F,Yuan Z,Xue J,Lu T,Huang W,Liu Y,Zhang Y
Sun Jul 10 00:00:00 EDT 2022
GSTM3 deficiency impedes DNA mismatch repair to promote gastric tumorigenesis via CAND1/NRF2-KEAP1 signaling.
Cancer letters
Chen T,Jinlin D,Wang F,Yuan Z,Xue J,Lu T,Huang W,Liu Y,Zhang Y
Sun Jul 10 00:00:00 EDT 2022
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer's disease mice and glutamate-injured HT22 cells.
Chinese medicine
Yang S,Xie Z,Pei T,Zeng Y,Xiong Q,Wei H,Wang Y,Cheng W
Mon Jul 04 00:00:00 EDT 2022
Accelerated Bone Regeneration by an Astaxanthin-Modified Antioxidant Aerogel through Relieving Oxidative Stress via the NRF2 Signaling Pathway.
ACS biomaterials science & engineering
Guo J,Yang X,Chen J,Wang C,Kang Y,Jiang T,Chen M,Li W,Zhou C,Chen Z
Mon Oct 10 00:00:00 EDT 2022
Accelerated Bone Regeneration by an Astaxanthin-Modified Antioxidant Aerogel through Relieving Oxidative Stress via the NRF2 Signaling Pathway.
ACS biomaterials science & engineering
Guo J,Yang X,Chen J,Wang C,Kang Y,Jiang T,Chen M,Li W,Zhou C,Chen Z
Mon Oct 10 00:00:00 EDT 2022
Relationship between Neuroprotective Effects and Structure of Procyanidins.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Apr 02 00:00:00 EDT 2022
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Cell death discovery
Ma H,Xie C,Chen Z,He G,Dai Z,Cai H,Zhang H,Lu H,Wu H,Hu X,Zhou K,Zheng G,Xu H,Xu C
Tue Apr 19 00:00:00 EDT 2022
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Cell death discovery
Ma H,Xie C,Chen Z,He G,Dai Z,Cai H,Zhang H,Lu H,Wu H,Hu X,Zhou K,Zheng G,Xu H,Xu C
Tue Apr 19 00:00:00 EDT 2022
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Cell death discovery
Ma H,Xie C,Chen Z,He G,Dai Z,Cai H,Zhang H,Lu H,Wu H,Hu X,Zhou K,Zheng G,Xu H,Xu C
Tue Apr 19 00:00:00 EDT 2022
Obstructive Sleep Apnea Affects Lacrimal Gland Function.
Investigative ophthalmology & visual science
Wang S,He X,Li Q,Zhang Y,Hu J,Zong R,Zhuang J,Quantock AJ,Gao Y,Li W,Liu Z
Wed Mar 02 00:00:00 EST 2022
Salvianolate ameliorates renal tubular injury through the Keap1/Nrf2/ARE pathway in mouse kidney ischemia-reperfusion injury.
Journal of ethnopharmacology
Sun D,Cui S,Ma H,Zhu P,Li N,Zhang X,Zhang L,Xuan L,Li J
Fri Jul 15 00:00:00 EDT 2022
Omarigliptin Mitigates 6-Hydroxydopamine- or Rotenone-Induced Oxidative Toxicity in PC12 Cells by Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Actions.
Antioxidants (Basel, Switzerland)
Gouda NA,Cho J
Wed Sep 28 00:00:00 EDT 2022
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Frontiers in pharmacology
Wang J,Wang K,Ding L,Zhao P,Zhang C,Wang H,Yang Z,Liu Z
Tue Aug 30 00:00:00 EDT 2022
Myocytic androgen receptor overexpression does not affect sex differences in adaptation to chronic endurance exercise.
Biology of sex differences
Barsky ST,Monks DA
Sun Oct 23 00:00:00 EDT 2022
Anti-fatigue effect of hypericin in a chronic forced exercise mouse model.
Journal of ethnopharmacology
Sun Y,Liang C,Zheng L,Liu L,Li Z,Yang G,Li Y
Thu Feb 10 00:00:00 EST 2022
Carbon Monoxide-Releasing Molecule-3 Suppresses the Malignant Biological Behavior of Tongue Squamous Cell Carcinoma via Regulating Keap1/Nrf2/HO-1 Signaling Pathway.
BioMed research international
Dai Y,Chen H,Pan Y,Song H
Wed Sep 28 00:00:00 EDT 2022
Potential contribution of early endothelial progenitor cell (eEPC)-to-macrophage switching in the development of pulmonary plexogenic lesion.
Respiratory research
Shao FJ,Guo XL,Xu JX,Liu R,Li DY,Li QH,Zhou T,Fang C,Tan X
Sun Oct 23 00:00:00 EDT 2022
Potential contribution of early endothelial progenitor cell (eEPC)-to-macrophage switching in the development of pulmonary plexogenic lesion.
Respiratory research
Shao FJ,Guo XL,Xu JX,Liu R,Li DY,Li QH,Zhou T,Fang C,Tan X
Sun Oct 23 00:00:00 EDT 2022
Bioinspired Multifunctional Black Phosphorus Hydrogel with Antibacterial and Antioxidant Properties: A Stepwise Countermeasure for Diabetic Skin Wound Healing.
Advanced healthcare materials
Ding Q,Sun T,Su W,Jing X,Ye B,Su Y,Zeng L,Qu Y,Yang X,Wu Y,Luo Z,Guo X
Wed Jun 01 00:00:00 EDT 2022
Glyphosate-induced gut microbiota dysbiosis facilitates male reproductive toxicity in rats.
The Science of the total environment
Liu JB,Chen K,Li ZF,Wang ZY,Wang L
Thu Jan 20 00:00:00 EST 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells.
Journal of fungi (Basel, Switzerland)
Sun T,Zhang Q,Li M,Tang S,Dai C
Fri Jul 22 00:00:00 EDT 2022
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Journal of agricultural and food chemistry
Du L,Hao YM,Yang YH,Zheng Y,Wu ZJ,Zhou MQ,Wang BZ,Wang YM,Wu H,Su GH
Wed Mar 09 00:00:00 EST 2022
Constant light in early life induces fear-related behavior in chickens with suppressed melatonin secretion and disrupted hippocampal expression of clock- and BDNF-associated genes.
Journal of animal science and biotechnology
Yang Y,Cong W,Liu J,Zhao M,Xu P,Han W,Wang D,Zhao R
Tue Jun 21 00:00:00 EDT 2022
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Journal of applied toxicology : JAT
Liu YP,Yuan XY,Li XY,Wang Y,Sun ZB,Deng WH,Lei YD,Huang L,Jiang TY,Zhang ZH
Tue Feb 01 00:00:00 EST 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
WASH regulates the oxidative stress Nrf2/ARE pathway to inhibit proliferation and promote apoptosis of HeLa cells under the action of Jolkinolide B.
PeerJ
Hong Y,Liu J,Kong W,Li H,Cui Y,Liu Y,Deng Z,Ma D,Zhang K,Li J,Li M
Mon Jan 23 00:00:00 EST 2023
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Antioxidants (Basel, Switzerland)
Li DM,Wu YX,Hu ZQ,Wang TC,Zhang LL,Zhou Y,Tong X,Xu JY,Qin LQ
Sun Jul 31 00:00:00 EDT 2022
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Frontiers in pharmacology
Ma T,Jia L,Zhao J,Lv L,Yu Y,Ruan H,Song X,Chen H,Li X,Zhang J,Gao L
Fri Nov 18 00:00:00 EST 2022
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Frontiers in pharmacology
Ma T,Jia L,Zhao J,Lv L,Yu Y,Ruan H,Song X,Chen H,Li X,Zhang J,Gao L
Fri Nov 18 00:00:00 EST 2022
Protective Effect of Danshen Zexie Decoction Against Non-Alcoholic Fatty Liver Disease Through Inhibition of ROS/NLRP3/IL-1β Pathway by Nrf2 Signaling Activation.
Frontiers in pharmacology
Biao Y,Chen J,Liu C,Wang R,Han X,Li L,Zhang Y
Sat Jul 16 00:00:00 EDT 2022
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination.
Cell death & disease
Zhang B,Bao W,Zhang S,Chen B,Zhou X,Zhao J,Shi Z,Zhang T,Chen Z,Wang L,Zheng X,Chen G,Wang Y
Thu Aug 25 00:00:00 EDT 2022
Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway.
Antioxidants (Basel, Switzerland)
Dai C,Zhang Q,Shen L,Sharma G,Jiang H,Wang Z,Shen J
Sat Jul 30 00:00:00 EDT 2022
Design of Diselenide-Bridged Hyaluronic Acid Nano-antioxidant for Efficient ROS Scavenging to Relieve Colitis.
ACS nano
Xu J,Chu T,Yu T,Li N,Wang C,Li C,Zhang Y,Meng H,Nie G
Tue Aug 23 00:00:00 EDT 2022
Traditional Chinese medicine prescriptions (XJZ, JSS) ameliorate spleen inflammatory response and antioxidant capacity by synergistically regulating NF-κB and Nrf2 signaling pathways in piglets.
Frontiers in veterinary science
Chen J,Hu N,Mao Y,Hu A,Jiang W,Huang A,Wang Y,Meng P,Hu M,Yang X,Cao Y,Yang F,Cao H
Tue Oct 04 00:00:00 EDT 2022
Aucubin promotes bone-fracture healing via the dual effects of anti-oxidative damage and enhancing osteoblastogenesis of hBM-MSCs.
Stem cell research & therapy
Wang K,Zhou C,Li L,Dai C,Wang Z,Zhang W,Xu J,Zhu Y,Pan Z
Fri Aug 19 00:00:00 EDT 2022
Aucubin promotes bone-fracture healing via the dual effects of anti-oxidative damage and enhancing osteoblastogenesis of hBM-MSCs.
Stem cell research & therapy
Wang K,Zhou C,Li L,Dai C,Wang Z,Zhang W,Xu J,Zhu Y,Pan Z
Fri Aug 19 00:00:00 EDT 2022
Acute lung inflammation induced by zinc oxide nanoparticles: Evolution and intervention via NRF2 activator.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Guo T,Fang X,Liu Y,Ruan Y,Hu Y,Wang X,Hu Y,Wang G,Xu Y
Fri Apr 01 00:00:00 EDT 2022
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
Cell death & disease
Ni L,Xiao J,Zhang D,Shao Z,Huang C,Wang S,Wu Y,Tian N,Sun L,Wu A,Zhou Y,Wang X,Zhang X
Thu Feb 10 00:00:00 EST 2022
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
Cell death & disease
Ni L,Xiao J,Zhang D,Shao Z,Huang C,Wang S,Wu Y,Tian N,Sun L,Wu A,Zhou Y,Wang X,Zhang X
Thu Feb 10 00:00:00 EST 2022
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kang H,Guo Q,Dong Y,Peng R,Song K,Wang J,Liu H,Zhu M,Zhao H,Guan H,Li F
Tue Feb 01 00:00:00 EST 2022
Eugenol Attenuates Transmissible Gastroenteritis Virus-Induced Oxidative Stress and Apoptosis Via ROS-NRF2-ARE Signaling.
Antioxidants (Basel, Switzerland)
Wang K,Tang Y,Wu X,Liang H,Chen D,Yu B,He J,Mao X,Huang Z,Yan H,Wu A,Luo Y,Zheng P,Yu J,Wang H,Luo J
Sun Sep 18 00:00:00 EDT 2022
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li S,Ma Y,Ye S,Su Y,Hu D,Xiao F
Wed Jun 01 00:00:00 EDT 2022
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li S,Ma Y,Ye S,Su Y,Hu D,Xiao F
Wed Jun 01 00:00:00 EDT 2022
Chronic exposure to propylparaben at the humanly relevant dose triggers ovarian aging in adult mice.
Ecotoxicology and environmental safety
Yan W,Li M,Guo Q,Li X,Zhou S,Dai J,Zhang J,Wu M,Tang W,Wen J,Xue L,Jin Y,Luo A,Wang S
Fri Apr 15 00:00:00 EDT 2022
Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway.
International immunopharmacology
Liu L,Shi Q,Wang K,Qian Y,Zhou L,Bellusci S,Chen C,Dong N
Thu Dec 01 00:00:00 EST 2022
Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway.
International immunopharmacology
Liu L,Shi Q,Wang K,Qian Y,Zhou L,Bellusci S,Chen C,Dong N
Thu Dec 01 00:00:00 EST 2022
Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway.
International immunopharmacology
Liu L,Shi Q,Wang K,Qian Y,Zhou L,Bellusci S,Chen C,Dong N
Thu Dec 01 00:00:00 EST 2022
Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway.
International immunopharmacology
Liu L,Shi Q,Wang K,Qian Y,Zhou L,Bellusci S,Chen C,Dong N
Thu Dec 01 00:00:00 EST 2022
Angiotensin (1-7) protects against renal ischemia-reperfusion injury via regulating expression of NRF2 and microRNAs in Fisher 344 rats.
American journal of physiology. Renal physiology
Zaman A,Banday AA
Fri Jul 01 00:00:00 EDT 2022
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Frontiers in molecular biosciences
Liang Z,Miao Y,Teng X,Xiao L,Guo Q,Xue H,Tian D,Jin S,Wu Y
Tue Aug 09 00:00:00 EDT 2022
Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma.
Frontiers in pharmacology
Xiu Z,Zhu Y,Han J,Li Y,Yang X,Yang G,Song G,Li S,Li Y,Cheng C,Li Y,Fang J,Li X,Jin N
Fri Jul 29 00:00:00 EDT 2022
Adaptive mechanisms in no flow vs. low flow ischemia in equine jejunum epithelium: Different paths to the same destination.
Frontiers in veterinary science
Dengler F,Sternberg F,Grages M,Kästner SB,Verhaar N
Wed Sep 28 00:00:00 EDT 2022
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Frontiers in nutrition
He C,Gao M,Zhang X,Lei P,Yang H,Qing Y,Zhang L
Sat Jul 16 00:00:00 EDT 2022
A plant-derived natural photosynthetic system for improving cell anabolism.
Nature
Chen P,Liu X,Gu C,Zhong P,Song N,Li M,Dai Z,Fang X,Liu Z,Zhang J,Tang R,Fan S,Lin X
Thu Dec 01 00:00:00 EST 2022
A plant-derived natural photosynthetic system for improving cell anabolism.
Nature
Chen P,Liu X,Gu C,Zhong P,Song N,Li M,Dai Z,Fang X,Liu Z,Zhang J,Tang R,Fan S,Lin X
Thu Dec 01 00:00:00 EST 2022
A plant-derived natural photosynthetic system for improving cell anabolism.
Nature
Chen P,Liu X,Gu C,Zhong P,Song N,Li M,Dai Z,Fang X,Liu Z,Zhang J,Tang R,Fan S,Lin X
Thu Dec 01 00:00:00 EST 2022
A plant-derived natural photosynthetic system for improving cell anabolism.
Nature
Chen P,Liu X,Gu C,Zhong P,Song N,Li M,Dai Z,Fang X,Liu Z,Zhang J,Tang R,Fan S,Lin X
Thu Dec 01 00:00:00 EST 2022
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Biochemical pharmacology
Kang H,Dong Y,Peng R,Liu H,Guo Q,Song K,Zhu M,Yu K,Wu W,Li F
Tue Mar 01 00:00:00 EST 2022
Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo.
Frontiers in pharmacology
Jiang Z,Qi G,Lu W,Wang H,Li D,Chen W,Ding L,Yang X,Yuan H,Zeng Q
Sat Oct 15 00:00:00 EDT 2022
Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells.
Frontiers in nutrition
Wang M,Huang H,Wang L,Yin L,Yang H,Chen C,Zheng Q,He S
Tue Nov 22 00:00:00 EST 2022
Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response.
Antioxidants (Basel, Switzerland)
De Backer J,Maric D,Zuhra K,Bogaerts A,Szabo C,Vanden Berghe W,Hoogewijs D
Wed Aug 10 00:00:00 EDT 2022
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Oncogene
Li Y,Yang J,Zhang Q,Xu S,Sun W,Ge S,Xu X,Jager MJ,Jia R,Zhang J,Fan X
Fri Jul 01 00:00:00 EDT 2022
Nrf2 and NF-κB/NLRP3 inflammasome pathways are involved in Prototheca bovis infections of mouse mammary gland tissue and mammary epithelial cells.
Free radical biology & medicine
Zhao W,Deng Z,Barkema HW,Xu M,Gao J,Liu G,Lin Y,Kastelic JP,Han B
Sun May 01 00:00:00 EDT 2022
18β-Glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice.
Scientific reports
Liu J,Xu Y,Yan M,Yu Y,Guo Y
Thu Feb 24 00:00:00 EST 2022
Corrigendum to "Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway".
Evidence-based complementary and alternative medicine : eCAM
Ding B,Geng S,Hou X,Ma X,Xu H,Yang F,Liu K,Liang W,Ma G
Thu Aug 18 00:00:00 EDT 2022
Nrf2 Transcriptional Activity Governs Intestine Development.
International journal of molecular sciences
Kopacz A,Kloska D,Klimczyk D,Kopec M,Jozkowicz A,Piechota-Polanczyk A
Tue May 31 00:00:00 EDT 2022
Improvement in heat stress-induced multiple organ dysfunction and intestinal damage through protection of intestinal goblet cells from prostaglandin E1 analogue misoprostol.
Life sciences
Hii HP,Lo WZ,Fu YH,Chen MH,Shih CC,Tsao CM,Ka SM,Chiu YL,Wu CC,Shih CC
Thu Dec 01 00:00:00 EST 2022
Enhanced Extracellular Matrix Degradation in Growth Plate Contributes to Manganese Deficiency-Induced Tibial Dyschondroplasia in Broiler Chicks.
Biological trace element research
Dong PF,Jin C,Lian CY,Wang L,Wang ZY
Fri Jul 01 00:00:00 EDT 2022
Activation of Nrf2/HO-1 Antioxidant Pathway by Heme Attenuates Calcification of Human Lens Epithelial Cells.
Pharmaceuticals (Basel, Switzerland)
Chowdhury A,Balogh E,Ababneh H,Tóth A,Jeney V
Tue Apr 19 00:00:00 EDT 2022
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Oxidative medicine and cellular longevity
Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z
Mon Apr 25 00:00:00 EDT 2022
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Oxidative medicine and cellular longevity
Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z
Mon Apr 25 00:00:00 EDT 2022
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Oxidative medicine and cellular longevity
Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z
Mon Apr 25 00:00:00 EDT 2022
Adipokine ZAG Alters Depression-Like Behavior by Regulating Oxidative Stress in Hippocampus.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Sun H,Ma F,Chen W,Yang X
Fri Apr 01 00:00:00 EDT 2022
Theaflavin Attenuates TBHP-Induced Endothelial Cells Oxidative Stress by Activating PI3K/AKT/Nrf2 and Accelerates Wound Healing in Rats.
Frontiers in bioengineering and biotechnology
Chen D,Wu Z,Wu LN,Jiang J,Hu GN
Tue Mar 22 00:00:00 EDT 2022
Theaflavin Attenuates TBHP-Induced Endothelial Cells Oxidative Stress by Activating PI3K/AKT/Nrf2 and Accelerates Wound Healing in Rats.
Frontiers in bioengineering and biotechnology
Chen D,Wu Z,Wu LN,Jiang J,Hu GN
Tue Mar 22 00:00:00 EDT 2022
Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways.
European journal of pharmacology
Zhang L,Zhu XZ,Badamjav R,Zhang JZ,Kou JP,Yu BY,Li F
Tue Feb 15 00:00:00 EST 2022
Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways.
European journal of pharmacology
Zhang L,Zhu XZ,Badamjav R,Zhang JZ,Kou JP,Yu BY,Li F
Tue Feb 15 00:00:00 EST 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Gao Y,Hu M,Niu X,Li M,Xu L,Xiao Y,Zhang J,Wang H,Li L,Chu B,Lv P
Tue Dec 13 00:00:00 EST 2022
The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1.
Oncogene
Gao M,Qi Z,Deng M,Huang H,Xu Z,Guo G,Jing J,Huang X,Xu M,Kloeber JA,Liu S,Huang J,Lou Z,Han J
Mon Aug 01 00:00:00 EDT 2022
Nrf2 Signaling Pathway Mediates the Protective Effects of Daphnetin Against D-Galactose Induced-Premature Ovarian Failure.
Frontiers in pharmacology
Zhang M,Yu X,Li D,Ma N,Wei Z,Ci X,Zhang S
Wed Feb 16 00:00:00 EST 2022
Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway.
Molecular metabolism
Li H,Yuan Y,Chen H,Dai H,Li J
Thu Dec 01 00:00:00 EST 2022
Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1.
Frontiers in pharmacology
Shi H,Hou B,Li H,Zhou H,Du B
Fri Mar 11 00:00:00 EST 2022
Exercise and Metformin Intervention Prevents Lipotoxicity-Induced Hepatocyte Apoptosis by Alleviating Oxidative and ER Stress and Activating the AMPK/Nrf2/HO-1 Signaling Pathway in db/db Mice.
Oxidative medicine and cellular longevity
Zhang Y,Liu Y,Liu X,Yuan X,Xiang M,Liu J,Zhang L,Zhu S,Lu J,Tang Q,Cheng S
Tue Sep 20 00:00:00 EDT 2022
Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal cord injury.
International immunopharmacology
Xia M,Zhang Y,Wu H,Zhang Q,Liu Q,Li G,Zhao T,Liu X,Zheng S,Qian Z,Li H
Sat Oct 01 00:00:00 EDT 2022
Reciprocal regulation of NRF2 by autophagy and ubiquitin-proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles.
Journal of nanobiotechnology
Li N,Du H,Mao L,Xu G,Zhang M,Fan Y,Dong X,Zheng L,Wang B,Qin X,Jiang X,Chen C,Zou Z,Zhang J
Sat Jun 11 00:00:00 EDT 2022
Reciprocal regulation of NRF2 by autophagy and ubiquitin-proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles.
Journal of nanobiotechnology
Li N,Du H,Mao L,Xu G,Zhang M,Fan Y,Dong X,Zheng L,Wang B,Qin X,Jiang X,Chen C,Zou Z,Zhang J
Sat Jun 11 00:00:00 EDT 2022
Reciprocal regulation of NRF2 by autophagy and ubiquitin-proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles.
Journal of nanobiotechnology
Li N,Du H,Mao L,Xu G,Zhang M,Fan Y,Dong X,Zheng L,Wang B,Qin X,Jiang X,Chen C,Zou Z,Zhang J
Sat Jun 11 00:00:00 EDT 2022
Reciprocal regulation of NRF2 by autophagy and ubiquitin-proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles.
Journal of nanobiotechnology
Li N,Du H,Mao L,Xu G,Zhang M,Fan Y,Dong X,Zheng L,Wang B,Qin X,Jiang X,Chen C,Zou Z,Zhang J
Sat Jun 11 00:00:00 EDT 2022
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
International journal of biological sciences
Li Q,Tan JX,He Y,Bai F,Li SW,Hou YW,Ji LS,Gao YT,Zhang X,Zhou ZH,Yu Z,Fang M,Gao YQ,Li M
Fri Apr 15 00:00:00 EDT 2022
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Free radical biology & medicine
Li T,Geng Z,Zhang J,Xu L,Zhu X
Sun Nov 20 00:00:00 EST 2022
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Free radical biology & medicine
Li T,Geng Z,Zhang J,Xu L,Zhu X
Sun Nov 20 00:00:00 EST 2022
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Oncology reports
Wang T,Liu J,Huang X,Zhang C,Shangguan M,Chen J,Wu S,Chen M,Yang Z,Zhao S
Tue Nov 01 00:00:00 EDT 2022
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Oncology reports
Wang T,Liu J,Huang X,Zhang C,Shangguan M,Chen J,Wu S,Chen M,Yang Z,Zhao S
Tue Nov 01 00:00:00 EDT 2022
Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway.
BMC complementary medicine and therapies
Chen Z,Liu H,Zhao X,Mamateli S,Liu C,Wang L,Yu J,Liu Y,Cai J,Qiao T
Thu Jul 07 00:00:00 EDT 2022
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Oxidative medicine and cellular longevity
Han GJ,Min XZ,Ma SS,Ding C,Wang XQ
Tue Dec 20 00:00:00 EST 2022
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration.
ACS applied materials & interfaces
Xu Z,Liu Y,Ma R,Chen J,Qiu J,Du S,Li C,Wu Z,Yang X,Chen Z,Chen T
Wed Mar 30 00:00:00 EDT 2022
Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities.
Bioorganic & medicinal chemistry
Wang W,Xiong L,Li Y,Song Z,Sun D,Li H,Chen L
Tue Feb 15 00:00:00 EST 2022
Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities.
Bioorganic & medicinal chemistry
Wang W,Xiong L,Li Y,Song Z,Sun D,Li H,Chen L
Tue Feb 15 00:00:00 EST 2022
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
Molecular nutrition & food research
Chen L,Liu D,Mao M,Liu W,Wang Y,Liang Y,Cao W,Zhong X
Tue Nov 01 00:00:00 EDT 2022
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
Environmental science & technology
Chen GH,Song CC,Zhao T,Hogstrand C,Wei XL,Lv WH,Song YF,Luo Z
Tue Feb 15 00:00:00 EST 2022
Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1-Nrf2.
Marine drugs
Xiao X,Tong Z,Zhang Y,Zhou H,Luo M,Hu T,Hu P,Kong L,Liu Z,Yu C,Huang Z,Hu L
Fri Mar 04 00:00:00 EST 2022
Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1-Nrf2.
Marine drugs
Xiao X,Tong Z,Zhang Y,Zhou H,Luo M,Hu T,Hu P,Kong L,Liu Z,Yu C,Huang Z,Hu L
Fri Mar 04 00:00:00 EST 2022
Spatial Analysis of NQO1 in Non-Small Cell Lung Cancer Shows Its Expression Is Independent of NRF1 and NRF2 in the Tumor Microenvironment.
Biomolecules
Kaghazchi B,Um IH,Elshani M,Read OJ,Harrison DJ
Tue Nov 08 00:00:00 EST 2022
Spatial Analysis of NQO1 in Non-Small Cell Lung Cancer Shows Its Expression Is Independent of NRF1 and NRF2 in the Tumor Microenvironment.
Biomolecules
Kaghazchi B,Um IH,Elshani M,Read OJ,Harrison DJ
Tue Nov 08 00:00:00 EST 2022
Cytoglobin inhibits non-thermal plasma-induced apoptosis in melanoma cells through regulation of the NRF2-mediated antioxidant response.
Redox biology
De Backer J,Lin A,Berghe WV,Bogaerts A,Hoogewijs D
Thu Sep 01 00:00:00 EDT 2022
Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.
Iranian journal of pharmaceutical research : IJPR
Chai N,Zheng H,Zhang H,Li L,Yu X,Wang L,Bi X,Yang L,Niu T,Liu X,Zhao Y,Dong L
Thu Dec 01 00:00:00 EST 2022
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Stem cell research & therapy
Yin BF,Li ZL,Yan ZQ,Guo Z,Liang JW,Wang Q,Zhao ZD,Li PL,Hao RC,Han MY,Li XT,Mao N,Ding L,Chen DF,Gao Y,Zhu H
Tue Jun 07 00:00:00 EDT 2022
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhong T,Li M,Wu H,Wang D,Liu J,Xu Y,Fan Y
Wed Jun 01 00:00:00 EDT 2022
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhong T,Li M,Wu H,Wang D,Liu J,Xu Y,Fan Y
Wed Jun 01 00:00:00 EDT 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2.
Biochemical pharmacology
Sun X,Dong M,Gao Y,Wang Y,Du L,Liu Y,Wang Q,Ji K,He N,Wang J,Zhang M,Gu Y,Song H,Zhai H,Feng L,Xu C,Liu Q
Sun May 01 00:00:00 EDT 2022
Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2.
Biochemical pharmacology
Sun X,Dong M,Gao Y,Wang Y,Du L,Liu Y,Wang Q,Ji K,He N,Wang J,Zhang M,Gu Y,Song H,Zhai H,Feng L,Xu C,Liu Q
Sun May 01 00:00:00 EDT 2022
Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2.
Biochemical pharmacology
Sun X,Dong M,Gao Y,Wang Y,Du L,Liu Y,Wang Q,Ji K,He N,Wang J,Zhang M,Gu Y,Song H,Zhai H,Feng L,Xu C,Liu Q
Sun May 01 00:00:00 EDT 2022
Immature rat testis sustained long-term development using an integrative model.
Biological research
Ma Y,Chen J,Li H,Xu F,Chong T,Wang Z,Zhang L
Tue Oct 04 00:00:00 EDT 2022
Emodin ameliorates antioxidant capacity and exerts neuroprotective effect via PKM2-mediated Nrf2 transactivation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ding Z,Da HH,Osama A,Xi J,Hou Y,Fang J
Tue Feb 01 00:00:00 EST 2022
Emodin ameliorates antioxidant capacity and exerts neuroprotective effect via PKM2-mediated Nrf2 transactivation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ding Z,Da HH,Osama A,Xi J,Hou Y,Fang J
Tue Feb 01 00:00:00 EST 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
A transcriptomics and molecular biology based investigation reveals the protective effect and mechanism of carnosol on t-BHP induced HRMECs via Nrf2 signaling pathway.
European journal of pharmacology
Ren Y,Liu Y,Liu K,Shu Z,Lv T,Chen Z,Feng W,Zhang Y
Sun May 15 00:00:00 EDT 2022
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Metabolic brain disease
Li F,Mao Q,Wang J,Zhang X,Lv X,Wu B,Yan T,Jia Y
Thu Dec 01 00:00:00 EST 2022
Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets.
Microbiome
Wang L,Liu Q,Chen Y,Zheng X,Wang C,Qi Y,Dong Y,Xiao Y,Chen C,Chen T,Huang Q,Zhai Z,Long C,Yang H,Li J,Wang L,Zhang G,Liao P,Liu YX,Huang P,Huang J,Wang Q,Chu H,Yin J,Yin Y
Wed Jun 01 00:00:00 EDT 2022
Nickel nanoparticles exert cytotoxic effects on trophoblast HTR-8/SVneo cells possibly via Nrf2/MAPK/caspase 3 pathway.
Environmental research
Li T,Li Z,Fu J,Tang C,Liu L,Xu J,Zhao J,Li Z
Thu Dec 01 00:00:00 EST 2022
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Molecules (Basel, Switzerland)
Zhou M,Dai Y,Ma Y,Yan Y,Hua M,Gao Q,Geng X,Zhou Q
Tue Jun 14 00:00:00 EDT 2022
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
Food & function
Zhang X,Zhang B,Li L,Li X,Zhang J,Chen G
Mon Aug 01 00:00:00 EDT 2022
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
In vitro cellular & developmental biology. Animal
Chen TY,Zheng SK
Sat Oct 01 00:00:00 EDT 2022
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zhou W,Dong G,Gao G,He Z,Xu J,Aziz S,Ma L,Zhao W
Mon Aug 01 00:00:00 EDT 2022
Suhuang antitussive capsule ameliorates post-infectious cough in mice through AhR-Nrf2 pathway.
Journal of ethnopharmacology
Liang R,Tong X,Dong Z,Qin W,Fan L,Bai Z,Zhang Z,Xiang T,Wang Z,Tan N
Sun Jan 30 00:00:00 EST 2022
Flavokawain A alleviates the progression of mouse osteoarthritis: An in vitro and in vivo study.
Frontiers in bioengineering and biotechnology
Jing S,Wan J,Wang T,He Z,Ding Q,Sheng G,Wang S,Zhao H,Zhu Z,Wu H,Li W
Fri Dec 23 00:00:00 EST 2022
Effect of thymoquinone on sepsis-induced cardiac damage via anti-inflammatory and anti-apoptotic mechanisms.
The Journal of international medical research
Guo W,Long X,Lv M,Deng S,Liu D,Yang Q
Thu Sep 01 00:00:00 EDT 2022
DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway.
Cell communication and signaling : CCS
Chu X,Zhong L,Dan W,Wang X,Zhang Z,Liu Z,Lu Y,Shao X,Zhou Z,Chen S,Liu B
Thu Oct 27 00:00:00 EDT 2022
DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway.
Cell communication and signaling : CCS
Chu X,Zhong L,Dan W,Wang X,Zhang Z,Liu Z,Lu Y,Shao X,Zhou Z,Chen S,Liu B
Thu Oct 27 00:00:00 EDT 2022
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM2.5.
Ecotoxicology and environmental safety
Shi F,Zhang Z,Cui H,Wang J,Wang Y,Tang Y,Yang W,Zou P,Ling X,Han F,Liu J,Chen Q,Liu C,Cao J,Ao L
Wed Jun 15 00:00:00 EDT 2022
The Inflammatory Response in Human Keratinocytes Exposed to Cinnamaldehyde Is Regulated by Nrf2.
Antioxidants (Basel, Switzerland)
Vallion R,Hardonnière K,Bouredji A,Damiens MH,Deloménie C,Pallardy M,Ferret PJ,Kerdine-Römer S
Thu Mar 17 00:00:00 EDT 2022
Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium.
Environmental pollution (Barking, Essex : 1987)
Zhu J,Liu L,Ma J,Fu Q,Zheng Z,Du E,Xu Y,Zhang Z
Mon Aug 01 00:00:00 EDT 2022
Vitamin C Sensitizes Pancreatic Cancer Cells to Erastin-Induced Ferroptosis by Activating the AMPK/Nrf2/HMOX1 Pathway.
Oxidative medicine and cellular longevity
Liu Y,Huang P,Li Z,Xu C,Wang H,Jia B,Gong A,Xu M
Mon Dec 12 00:00:00 EST 2022
Vitamin C Sensitizes Pancreatic Cancer Cells to Erastin-Induced Ferroptosis by Activating the AMPK/Nrf2/HMOX1 Pathway.
Oxidative medicine and cellular longevity
Liu Y,Huang P,Li Z,Xu C,Wang H,Jia B,Gong A,Xu M
Mon Dec 12 00:00:00 EST 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 EDT 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 EDT 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 EDT 2022
Bone marrow-derived mesenchymal stem cells ameliorate severe acute pancreatitis by inhibiting oxidative stress in rats.
Molecular and cellular biochemistry
Zhao D,Yu W,Xie W,Ma Z,Hu Z,Song Z
Thu Dec 01 00:00:00 EST 2022
Bone marrow-derived mesenchymal stem cells ameliorate severe acute pancreatitis by inhibiting oxidative stress in rats.
Molecular and cellular biochemistry
Zhao D,Yu W,Xie W,Ma Z,Hu Z,Song Z
Thu Dec 01 00:00:00 EST 2022
Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages.
Antioxidants (Basel, Switzerland)
Yang T,Zhao Q,Hu M,Pan S,Zhang L,Zhu R,Zhou B,Feng X,Gao Z,Zhu Z,Zhang Y,Hu L,Liu F,Shan Z
Tue Oct 18 00:00:00 EDT 2022
Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages.
Antioxidants (Basel, Switzerland)
Yang T,Zhao Q,Hu M,Pan S,Zhang L,Zhu R,Zhou B,Feng X,Gao Z,Zhu Z,Zhang Y,Hu L,Liu F,Shan Z
Tue Oct 18 00:00:00 EDT 2022
Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages.
Antioxidants (Basel, Switzerland)
Yang T,Zhao Q,Hu M,Pan S,Zhang L,Zhu R,Zhou B,Feng X,Gao Z,Zhu Z,Zhang Y,Hu L,Liu F,Shan Z
Tue Oct 18 00:00:00 EDT 2022
Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages.
Antioxidants (Basel, Switzerland)
Yang T,Zhao Q,Hu M,Pan S,Zhang L,Zhu R,Zhou B,Feng X,Gao Z,Zhu Z,Zhang Y,Hu L,Liu F,Shan Z
Tue Oct 18 00:00:00 EDT 2022
Trimetazidine and exercise offer analogous improvements to the skeletal muscle insulin resistance of mice through Nrf2 signaling.
BMJ open diabetes research & care
Zhang W,Dun Y,You B,Qiu L,Ripley-Gonzalez JW,Cheng J,Fu S,Li C,Liu S
Tue Mar 01 00:00:00 EST 2022
Lactiplantibacillus plantarum 299v supplementation modulates β-cell ER stress and antioxidative defense pathways and prevents type 1 diabetes in gluten-free BioBreeding rats.
Gut microbes
Sargin P,Roethle MF,Jia S,Pant T,Ciecko AE,Atkinson SN,Salzman NH,Teng RJ,Chen YG,Cabrera SM,Hessner MJ
Fri Oct 21 00:00:00 EDT 2022
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Journal of molecular and cellular cardiology
Chen Y,Bao M,Liu JT,Bao H,Zhang SM,Lou Y,Qi YX
Thu Dec 01 00:00:00 EST 2022
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Journal of molecular and cellular cardiology
Chen Y,Bao M,Liu JT,Bao H,Zhang SM,Lou Y,Qi YX
Thu Dec 01 00:00:00 EST 2022
Overexpressed Smurf1 is degraded in glioblastoma cells through autophagy in a p62-dependent manner.
FEBS open bio
Han D,Li S,Xia Q,Meng X,Dong L
Sat Jan 01 00:00:00 EST 2022
Basic fibroblast growth factor protects against liver ischemia-reperfusion injury via the Nrf2/Hippo signaling pathway.
Tissue & cell
Chen X,Tong G,Chen S
Thu Dec 01 00:00:00 EST 2022
Basic fibroblast growth factor protects against liver ischemia-reperfusion injury via the Nrf2/Hippo signaling pathway.
Tissue & cell
Chen X,Tong G,Chen S
Thu Dec 01 00:00:00 EST 2022
Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects.
Journal of medicinal chemistry
He ZX,An Q,Wei B,Zhou WJ,Wei BF,Gong YP,Zhang X,Gao G,Dong GJ,Huo JL,Zhang XH,Yang FF,Liu HM,Ma LY,Zhao W
Thu Jan 13 00:00:00 EST 2022
Buformin alleviates sepsis-induced acute lung injury via inhibiting NLRP3-mediated pyroptosis through an AMPK-dependent pathway.
Clinical science (London, England : 1979)
Liu B,Wang Z,He R,Xiong R,Li G,Zhang L,Fu T,Li C,Li N,Geng Q
Fri Feb 25 00:00:00 EST 2022
Elucidation of an mTORC2-PKC-NRF2 pathway that sustains the ATF4 stress response and identification of Sirt5 as a key ATF4 effector.
Cell death discovery
Li R,Wilson KF,Cerione RA
Sat Aug 13 00:00:00 EDT 2022
Mesenchymal stem cells improve redox homeostasis and mitochondrial respiration in fibroblast cell lines with pathogenic MT-ND3 and MT-ND6 variants.
Stem cell research & therapy
Navaratnarajah T,Bellmann M,Seibt A,Anand R,Degistirici Ö,Meisel R,Mayatepek E,Reichert A,Baertling F,Distelmaier F
Fri Jun 17 00:00:00 EDT 2022
Fibroblast Growth Factor 19 Improves LPS-Induced Lipid Disorder and Organ Injury by Regulating Metabolomic Characteristics in Mice.
Oxidative medicine and cellular longevity
Liu T,Tang X,Cui Y,Xiong X,Xu Y,Hu S,Feng S,Shao L,Ren Y,Miao H,Zhang H,Zhu X,Zhang Y,Wang C
Tue Jul 19 00:00:00 EDT 2022
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway.
The Journal of investigative dermatology
Wang S,Yi X,Wu Z,Guo S,Dai W,Wang H,Shi Q,Zeng K,Guo W,Li C
Sat Jan 01 00:00:00 EST 2022
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway.
The Journal of investigative dermatology
Wang S,Yi X,Wu Z,Guo S,Dai W,Wang H,Shi Q,Zeng K,Guo W,Li C
Sat Jan 01 00:00:00 EST 2022
Activation of AMPK/p38/Nrf2 is involved in resveratrol alleviating myocardial ischemia-reperfusion injury in diabetic rats as an endogenous antioxidant stress feedback.
Annals of translational medicine
Xu G,Ma Y,Jin J,Wang X
Mon Aug 01 00:00:00 EDT 2022
Hawk Tea Flavonoids as Natural Hepatoprotective Agents Alleviate Acute Liver Damage by Reshaping the Intestinal Microbiota and Modulating the Nrf2 and NF-κB Signaling Pathways.
Nutrients
Xu T,Hu S,Liu Y,Sun K,Luo L,Zeng L
Mon Sep 05 00:00:00 EDT 2022
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
European journal of histochemistry : EJH
Chen Z,Wang H,Hu B,Chen X,Zheng M,Liang L,Lyu J,Zeng Q
Tue Jun 21 00:00:00 EDT 2022
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
European journal of histochemistry : EJH
Chen Z,Wang H,Hu B,Chen X,Zheng M,Liang L,Lyu J,Zeng Q
Tue Jun 21 00:00:00 EDT 2022
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
European journal of histochemistry : EJH
Chen Z,Wang H,Hu B,Chen X,Zheng M,Liang L,Lyu J,Zeng Q
Tue Jun 21 00:00:00 EDT 2022
Yinchen Linggui Zhugan decoction ameliorates high fat diet-induced nonalcoholic fatty liver disease by modulation of SIRT1/Nrf2 signaling pathway and gut microbiota.
Frontiers in microbiology
Jiang H,Mao T,Sun Z,Shi L,Han X,Zhang Y,Zhang X,Wang J,Hu J,Zhang L,Li J,Han H
Tue Jan 03 00:00:00 EST 2023
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
Oxidative medicine and cellular longevity
Xu C,Ni S,Xu N,Yin G,Yu Y,Zhou B,Zhao G,Wang L,Zhu R,Jiang S,Wang Y
Mon Dec 12 00:00:00 EST 2022
Antioxidant Effects of Roasted Licorice in a Zebrafish Model and Its Mechanisms.
Molecules (Basel, Switzerland)
Zhou Q,Zhang S,Geng X,Jiang H,Dai Y,Wang P,Hua M,Gao Q,Lang S,Hou L,Shi D,Zhou M
Thu Nov 10 00:00:00 EST 2022
Hyperglycemia Induces Meibomian Gland Dysfunction.
Investigative ophthalmology & visual science
Guo Y,Zhang H,Zhao Z,Luo X,Zhang M,Bu J,Liang M,Wu H,Yu J,He H,Zong R,Chen Y,Liu Z,Li W
Mon Jan 03 00:00:00 EST 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 EDT 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 EDT 2022
Trans-anethole Ameliorates Intestinal Injury Through Activation of Nrf2 Signaling Pathway in Subclinical Necrotic Enteritis-Induced Broilers.
Frontiers in veterinary science
Yu C,Tong Y,Li Q,Wang T,Yang Z
Sat May 07 00:00:00 EDT 2022
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Bioorganic chemistry
Zhou X,Li X,Yi K,Liang C,Geng S,Zhu J,Xie C,Zhong C
Tue Nov 01 00:00:00 EDT 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway.
International immunopharmacology
Bai X,Zhu Y,Jie J,Li D,Song L,Luo J
Fri Jul 01 00:00:00 EDT 2022
Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Ning J,Huo XK,Xiao HT,Sun CP
Thu Dec 01 00:00:00 EST 2022
Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Ning J,Huo XK,Xiao HT,Sun CP
Thu Dec 01 00:00:00 EST 2022
Structure of the nutrient-sensing hub GATOR2.
Nature
Valenstein ML,Rogala KB,Lalgudi PV,Brignole EJ,Gu X,Saxton RA,Chantranupong L,Kolibius J,Quast JP,Sabatini DM
Fri Jul 01 00:00:00 EDT 2022
Genistein mitigates oxidative stress and inflammation by regulating Nrf2/HO-1 and NF-κB signaling pathways in hypoxic-ischemic brain damage in neonatal mice.
Annals of translational medicine
Li Y,Zhang JJ,Chen RJ,Chen L,Chen S,Yang XF,Min JW
Sat Jan 01 00:00:00 EST 2022
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Fundamental & clinical pharmacology
Xu L,Gao Y,Hu M,Dong Y,Xu J,Zhang J,Lv P
Sat Oct 01 00:00:00 EDT 2022
Trehalose prevents glyphosate-induced testicular damage in roosters via its antioxidative properties.
Research in veterinary science
Chen K,Liu JB,Tie CZ,Wang L
Tue Dec 20 00:00:00 EST 2022
ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation.
Redox biology
Zhang J,Liu L,Zhang Y,Yuan Y,Miao Z,Lu K,Zhang X,Ni R,Zhang H,Zhao Y,Wang X
Thu Dec 01 00:00:00 EST 2022
Salecan ameliorates liver injury by regulating gut microbiota and its metabolites.
Food & function
Li P,Liu Y,Zhao J,Pan W,He Y,Fu S,Liu Y,Xu YJ
Mon Nov 14 00:00:00 EST 2022
Salecan ameliorates liver injury by regulating gut microbiota and its metabolites.
Food & function
Li P,Liu Y,Zhao J,Pan W,He Y,Fu S,Liu Y,Xu YJ
Mon Nov 14 00:00:00 EST 2022
MCFA alleviate H2 O2 -induced oxidative stress in AML12 cells via the ERK1/2/Nrf2 pathway.
Lipids
Wang D,Chen J,Sun H,Chen W,Yang X
Sun May 01 00:00:00 EDT 2022
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
Free radical research
Zheng J,Wang Y,Wang Z,Chen W,Luo M,Zhang C,Wang Y,Chen L,Wu F,Yang W,Yang Z,Wang Y,Shi C
Wed Nov 30 00:00:00 EST 2022
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
Free radical research
Zheng J,Wang Y,Wang Z,Chen W,Luo M,Zhang C,Wang Y,Chen L,Wu F,Yang W,Yang Z,Wang Y,Shi C
Wed Nov 30 00:00:00 EST 2022
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
Free radical research
Zheng J,Wang Y,Wang Z,Chen W,Luo M,Zhang C,Wang Y,Chen L,Wu F,Yang W,Yang Z,Wang Y,Shi C
Wed Nov 30 00:00:00 EST 2022
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Oxidative medicine and cellular longevity
Wang L,Wang J
Fri Dec 30 00:00:00 EST 2022
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Oxidative medicine and cellular longevity
Wang L,Wang J
Fri Dec 30 00:00:00 EST 2022
Protective Effects of Three Flavonoids from Dendrobium huoshanense Flowers on Alcohol-Induced Hepatocyte Injury via Activating Nrf2 and Inhibiting NF-κB Pathways.
Chemistry & biodiversity
Li QM,Yang XR,Zha XQ,Pan LH,Zang DD,Zhang FY,Luo JP
Mon Aug 01 00:00:00 EDT 2022
GRP78 Antibodies Are Associated With Blood-Brain Barrier Breakdown in Anti-Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorder.
Neurology(R) neuroimmunology & neuroinflammation
Shimizu F,Ogawa R,Mizukami Y,Watanabe K,Hara K,Kadono C,Takahashi T,Misu T,Takeshita Y,Sano Y,Fujisawa M,Maeda T,Nakashima I,Fujihara K,Kanda T
Sat Jan 01 00:00:00 EST 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 EDT 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 EDT 2022
The neuroprotective effects of paeoniflorin against MPP+-induced damage to dopaminergic neurons via the Akt/Nrf2/GPX4 pathway.
Journal of chemical neuroanatomy
Wang L,An H,Yu F,Yang J,Ding H,Bao Y,Xie H,Huang D
Fri Jul 01 00:00:00 EDT 2022
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Journal of ethnopharmacology
Zhang XG,Liu AX,Zhang YX,Zhou MY,Li XY,Fu MH,Pan YP,Xu J,Zhang JQ
Thu Sep 15 00:00:00 EDT 2022
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
Cardiovascular research
Yao Y,Song Q,Hu C,Da X,Yu Y,He Z,Xu C,Chen Q,Wang QK
Fri Jan 07 00:00:00 EST 2022
Tea Tree Oil Mediates Antioxidant Factors Relish and Nrf2-Autophagy Axis Regulating the Lipid Metabolism of Macrobrachium rosenbergii.
Antioxidants (Basel, Switzerland)
Liu M,Zheng X,Sun C,Zhou Q,Liu B,Xu P
Wed Nov 16 00:00:00 EST 2022
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Bioengineered
Zhu W,Tang H,Li J,Guedes RM,Cao L,Guo C
Fri Apr 01 00:00:00 EDT 2022
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency.
Free radical biology & medicine
Yang R,Zhang J,Li J,Qin R,Chen J,Wang R,Goltzman D,Miao D
Sat Jan 01 00:00:00 EST 2022
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency.
Free radical biology & medicine
Yang R,Zhang J,Li J,Qin R,Chen J,Wang R,Goltzman D,Miao D
Sat Jan 01 00:00:00 EST 2022
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Oxidative medicine and cellular longevity
Han S,Lin F,Qi Y,Liu C,Zhou L,Xia Y,Chen K,Xing J,Liu Z,Yu W,Zhang Y,Zhou X,Rao T,Cheng F
Mon Jun 06 00:00:00 EDT 2022
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Theriogenology
Shi L,Wang X,Duan Y,Li K,Ren Y
Wed Jun 01 00:00:00 EDT 2022
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
Oxidative medicine and cellular longevity
Chen P,Yang J,Wu N,Han B,Kastelic JP,Gao J
Fri Mar 18 00:00:00 EDT 2022
Nrf2 Activation and NF-Kb & caspase/bax signaling inhibition by sodium butyrate alleviates LPS-induced cell injury in bovine mammary epithelial cells.
Molecular immunology
Ali I,Li C,Kuang M,Shah AU,Shafiq M,Ahmad MA,Abdalmegeed D,Li L,Wang G
Mon Aug 01 00:00:00 EDT 2022
Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
International journal of molecular sciences
Wang H,Hao W,Yang L,Li T,Zhao C,Yan P,Wei S
Thu Jul 14 00:00:00 EDT 2022
Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
International journal of molecular sciences
Wang H,Hao W,Yang L,Li T,Zhao C,Yan P,Wei S
Thu Jul 14 00:00:00 EDT 2022
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury.
Biochimica et biophysica acta. Molecular basis of disease
Feng Z,Qin Y,Huo F,Jian Z,Li X,Geng J,Li Y,Wu J
Sat Jan 01 00:00:00 EST 2022
Discovery of novel diphenylbutene derivative ferroptosis inhibitors as neuroprotective agents.
European journal of medicinal chemistry
Fang Y,Tan Q,Zhou H,Gu Q,Xu J
Sat Mar 05 00:00:00 EST 2022
Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1.
The Journal of biological chemistry
Chen Y,Li M,Yang Y,Lu Y,Li X
Thu Dec 01 00:00:00 EST 2022
Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury.
Antioxidants (Basel, Switzerland)
Bondi CD,Rush BM,Hartman HL,Wang J,Al-Bataineh MM,Hughey RP,Tan RJ
Wed Sep 14 00:00:00 EDT 2022
Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury.
Antioxidants (Basel, Switzerland)
Bondi CD,Rush BM,Hartman HL,Wang J,Al-Bataineh MM,Hughey RP,Tan RJ
Wed Sep 14 00:00:00 EDT 2022
Photoprotective Effects of Cannabidiol against Ultraviolet-B-Induced DNA Damage and Autophagy in Human Keratinocyte Cells and Mouse Skin Tissue.
Molecules (Basel, Switzerland)
Li Y,Hao D,Wei D,Xiao Y,Liu L,Li X,Wang L,Gan Y,Yan W,Ke B,Jiang X
Mon Oct 10 00:00:00 EDT 2022
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
European journal of pharmacology
Shi Y,Zhao L,Wang J,Liu S,Zhang Y,Qin Q
Thu Dec 15 00:00:00 EST 2022
Cycloastragenol suppresses M1 and promotes M2 polarization in LPS-stimulated BV-2 cells and ischemic stroke mice.
International immunopharmacology
Chen T,Li Z,Li S,Zou Y,Gao X,Shu S,Wang Z
Thu Dec 01 00:00:00 EST 2022
Cycloastragenol suppresses M1 and promotes M2 polarization in LPS-stimulated BV-2 cells and ischemic stroke mice.
International immunopharmacology
Chen T,Li Z,Li S,Zou Y,Gao X,Shu S,Wang Z
Thu Dec 01 00:00:00 EST 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 EDT 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 EDT 2022
Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER.
iScience
Inoue R,Tsuno T,Togashi Y,Okuyama T,Sato A,Nishiyama K,Kyohara M,Li J,Fukushima S,Kin T,Miyashita D,Shiba Y,Atobe Y,Kiyonari H,Bando K,Shapiro AMJ,Funakoshi K,Kulkarni RN,Terauchi Y,Shirakawa J
Fri Jul 15 00:00:00 EDT 2022
HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway.
Journal of physiology and biochemistry
Yuan Z,Xiao-Wei L,Juan W,Xiu-Juan L,Nian-Yun Z,Lei S
Mon Aug 01 00:00:00 EDT 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 EDT 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 EDT 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 EDT 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 EDT 2022
Pharmacological Effects of Gami-Yukmijihwang-Tang on the Lipopolysaccharide-Induced Hippocampus Oxidation and Inflammation via Regulation of Sirt6.
Pharmaceuticals (Basel, Switzerland)
Kang JY,Lee JS,Seol IC,Kim YS,Park MS,Yoo HR
Mon Feb 28 00:00:00 EST 2022
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Inflammation
Liu C,Li Y,Wang X
Mon Aug 01 00:00:00 EDT 2022
Oxidative stress in the RVLM mediates sympathetic hyperactivity induced by circadian disruption.
Neuroscience letters
Duan W,Ye P,Leng YQ,Liu DH,Sun JC,Tan X,Wang WZ
Sun Nov 20 00:00:00 EST 2022
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang D,Li L,Li J,Wei Y,Tang J,Man X,Liu F
Thu Sep 01 00:00:00 EDT 2022
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang D,Li L,Li J,Wei Y,Tang J,Man X,Liu F
Thu Sep 01 00:00:00 EDT 2022
Rutin Supplementation Reduces Oxidative Stress, Inflammation and Apoptosis of Mammary Gland in Sheep During the Transition Period.
Frontiers in veterinary science
Ding H,Li Y,Zhao C,Yang Y,Xiong C,Zhang D,Feng S,Wu J,Wang X
Fri Nov 03 00:00:00 EDT 2023
Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
Drug design, development and therapy
Wang J,Zhang Y,Zhang M,Sun S,Zhong Y,Han L,Xu Y,Wan D,Zhang J,Zhu H
Mon Mar 28 00:00:00 EDT 2022
Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62-Keap1-Nrf2 pathway.
Food & function
Jia Y,Guo H,Cheng X,Zhang Y,Si M,Shi J,Ma D
Mon Apr 04 00:00:00 EDT 2022
Fucoxanthin ameliorated myocardial fibrosis in STZ-induced diabetic rats and cell hypertrophy in HG-induced H9c2 cells by alleviating oxidative stress and restoring mitophagy.
Food & function
Zheng D,Chen L,Li G,Jin L,Wei Q,Liu Z,Yang G,Li Y,Xie X
Thu Sep 22 00:00:00 EDT 2022
Fucoxanthin ameliorated myocardial fibrosis in STZ-induced diabetic rats and cell hypertrophy in HG-induced H9c2 cells by alleviating oxidative stress and restoring mitophagy.
Food & function
Zheng D,Chen L,Li G,Jin L,Wei Q,Liu Z,Yang G,Li Y,Xie X
Thu Sep 22 00:00:00 EDT 2022
Fucoxanthin ameliorated myocardial fibrosis in STZ-induced diabetic rats and cell hypertrophy in HG-induced H9c2 cells by alleviating oxidative stress and restoring mitophagy.
Food & function
Zheng D,Chen L,Li G,Jin L,Wei Q,Liu Z,Yang G,Li Y,Xie X
Thu Sep 22 00:00:00 EDT 2022
Fucoxanthin ameliorated myocardial fibrosis in STZ-induced diabetic rats and cell hypertrophy in HG-induced H9c2 cells by alleviating oxidative stress and restoring mitophagy.
Food & function
Zheng D,Chen L,Li G,Jin L,Wei Q,Liu Z,Yang G,Li Y,Xie X
Thu Sep 22 00:00:00 EDT 2022
Trypsin inhibitor LH011 inhibited DSS-induced mice colitis via alleviating inflammation and oxidative stress.
Frontiers in pharmacology
Jia Z,Wang P,Xu Y,Feng G,Wang Q,He X,Song Y,Liu P,Chen J
Sat Oct 15 00:00:00 EDT 2022
Trypsin inhibitor LH011 inhibited DSS-induced mice colitis via alleviating inflammation and oxidative stress.
Frontiers in pharmacology
Jia Z,Wang P,Xu Y,Feng G,Wang Q,He X,Song Y,Liu P,Chen J
Sat Oct 15 00:00:00 EDT 2022
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.
Open biology
Xue J,Liao Q,Luo M,Hua C,Zhao J,Yu G,Chen X,Li X,Zhang X,Ran R,Lu F,Wang Y,Qiao L
Fri Apr 01 00:00:00 EDT 2022
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.
Open biology
Xue J,Liao Q,Luo M,Hua C,Zhao J,Yu G,Chen X,Li X,Zhang X,Ran R,Lu F,Wang Y,Qiao L
Fri Apr 01 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
Homeobox A1 Facilitates Immune Escape and Alleviates Oxidative Stress in Lung Adenocarcinoma.
Oxidative medicine and cellular longevity
Zhao F,Tian H,Liu X,Guan Y,Zhu Y,Ren P,Zhang J,Dong Y,Fu L
Thu Jun 02 00:00:00 EDT 2022
Homeobox A1 Facilitates Immune Escape and Alleviates Oxidative Stress in Lung Adenocarcinoma.
Oxidative medicine and cellular longevity
Zhao F,Tian H,Liu X,Guan Y,Zhu Y,Ren P,Zhang J,Dong Y,Fu L
Thu Jun 02 00:00:00 EDT 2022
Homeobox A1 Facilitates Immune Escape and Alleviates Oxidative Stress in Lung Adenocarcinoma.
Oxidative medicine and cellular longevity
Zhao F,Tian H,Liu X,Guan Y,Zhu Y,Ren P,Zhang J,Dong Y,Fu L
Thu Jun 02 00:00:00 EDT 2022
Targeting p21-activated kinase 4 (PAK4) with pyrazolo[3,4-d]pyrimidine derivative SPA7012 attenuates hepatic ischaemia-reperfusion injury in mice.
Journal of enzyme inhibition and medicinal chemistry
Mao Y,Lee E,Yang X,Bae EJ,Jeon R,Park BH
Thu Dec 01 00:00:00 EST 2022
Targeting p21-activated kinase 4 (PAK4) with pyrazolo[3,4-d]pyrimidine derivative SPA7012 attenuates hepatic ischaemia-reperfusion injury in mice.
Journal of enzyme inhibition and medicinal chemistry
Mao Y,Lee E,Yang X,Bae EJ,Jeon R,Park BH
Thu Dec 01 00:00:00 EST 2022
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
Ecotoxicology and environmental safety
Xue L,Li X,Zhu X,Zhang J,Zhou S,Tang W,Chen D,Chen Y,Dai J,Wu M,Wu M,Wang S
Thu Sep 01 00:00:00 EDT 2022
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Environmental toxicology
Zhai X,Dai T,Chi Z,Zhao Z,Wu G,Yang S,Dong D
Wed Jun 01 00:00:00 EDT 2022
Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways.
The Journal of nutritional biochemistry
Zhong CC,Zhao T,Hogstrand C,Chen F,Song CC,Luo Z
Tue Feb 01 00:00:00 EST 2022
Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways.
The Journal of nutritional biochemistry
Zhong CC,Zhao T,Hogstrand C,Chen F,Song CC,Luo Z
Tue Feb 01 00:00:00 EST 2022
Puerarin alleviates cadmium-induced rat neurocyte injury by alleviating Nrf2-mediated oxidative stress and inhibiting mitochondrial unfolded protein response.
Ecotoxicology and environmental safety
Zhang W,Xu M,Wen S,Wang L,Zhang K,Zhang C,Zou H,Gu J,Liu X,Bian J,Liu Z,Yuan Y
Thu Dec 01 00:00:00 EST 2022
Puerarin alleviates cadmium-induced rat neurocyte injury by alleviating Nrf2-mediated oxidative stress and inhibiting mitochondrial unfolded protein response.
Ecotoxicology and environmental safety
Zhang W,Xu M,Wen S,Wang L,Zhang K,Zhang C,Zou H,Gu J,Liu X,Bian J,Liu Z,Yuan Y
Thu Dec 01 00:00:00 EST 2022
Puerarin alleviates cadmium-induced rat neurocyte injury by alleviating Nrf2-mediated oxidative stress and inhibiting mitochondrial unfolded protein response.
Ecotoxicology and environmental safety
Zhang W,Xu M,Wen S,Wang L,Zhang K,Zhang C,Zou H,Gu J,Liu X,Bian J,Liu Z,Yuan Y
Thu Dec 01 00:00:00 EST 2022
Puerarin alleviates cadmium-induced rat neurocyte injury by alleviating Nrf2-mediated oxidative stress and inhibiting mitochondrial unfolded protein response.
Ecotoxicology and environmental safety
Zhang W,Xu M,Wen S,Wang L,Zhang K,Zhang C,Zou H,Gu J,Liu X,Bian J,Liu Z,Yuan Y
Thu Dec 01 00:00:00 EST 2022
Puerarin alleviates cadmium-induced rat neurocyte injury by alleviating Nrf2-mediated oxidative stress and inhibiting mitochondrial unfolded protein response.
Ecotoxicology and environmental safety
Zhang W,Xu M,Wen S,Wang L,Zhang K,Zhang C,Zou H,Gu J,Liu X,Bian J,Liu Z,Yuan Y
Thu Dec 01 00:00:00 EST 2022
Puerarin alleviates cadmium-induced rat neurocyte injury by alleviating Nrf2-mediated oxidative stress and inhibiting mitochondrial unfolded protein response.
Ecotoxicology and environmental safety
Zhang W,Xu M,Wen S,Wang L,Zhang K,Zhang C,Zou H,Gu J,Liu X,Bian J,Liu Z,Yuan Y
Thu Dec 01 00:00:00 EST 2022
TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 Pathway.
Inflammation
Chen Z,Tian L,Wang L,Ma X,Lei F,Chen X,Fu R
Wed Jun 01 00:00:00 EDT 2022
Inhibition of Nicotinamide adenine dinucleotide phosphate oxidase 4 attenuates cell apoptosis and oxidative stress in a rat model of polycystic ovary syndrome through the activation of Nrf-2/HO-1 signaling pathway.
Molecular and cellular endocrinology
Li Y,Xu J,Li L,Bai L,Wang Y,Zhang J,Wang H
Wed Jun 15 00:00:00 EDT 2022
Inhibition of Nicotinamide adenine dinucleotide phosphate oxidase 4 attenuates cell apoptosis and oxidative stress in a rat model of polycystic ovary syndrome through the activation of Nrf-2/HO-1 signaling pathway.
Molecular and cellular endocrinology
Li Y,Xu J,Li L,Bai L,Wang Y,Zhang J,Wang H
Wed Jun 15 00:00:00 EDT 2022
Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells.
Cell death & disease
Zhang M,Qiu H,Mao L,Wang B,Li N,Fan Y,Weng P,Hu S,Dong X,Qin X,Chen C,Zou Z,Yu C,Zhang J
Thu Aug 25 00:00:00 EDT 2022
Ammonium tetrathiomolybdate triggers autophagy-dependent NRF2 activation in vascular endothelial cells.
Cell death & disease
Zhang M,Qiu H,Mao L,Wang B,Li N,Fan Y,Weng P,Hu S,Dong X,Qin X,Chen C,Zou Z,Yu C,Zhang J
Thu Aug 25 00:00:00 EDT 2022
Protective effect of rutin against diabetes-associated cognitive decline in rats.
Pakistan journal of pharmaceutical sciences
Xianchu L,Huan P,Kang L,Beiwang D,Ming L
Sun May 01 00:00:00 EDT 2022
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.
Free radical biology & medicine
Chen GH,Song CC,Pantopoulos K,Wei XL,Zheng H,Luo Z
Sun Feb 20 00:00:00 EST 2022
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.
Free radical biology & medicine
Chen GH,Song CC,Pantopoulos K,Wei XL,Zheng H,Luo Z
Sun Feb 20 00:00:00 EST 2022
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.
Free radical biology & medicine
Chen GH,Song CC,Pantopoulos K,Wei XL,Zheng H,Luo Z
Sun Feb 20 00:00:00 EST 2022
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Acta pharmacologica Sinica
Dong J,Zhang KJ,Li GC,Chen XR,Lin JJ,Li JW,Lv ZY,Deng ZZ,Dai J,Cao W,Jiang Q
Fri Jul 01 00:00:00 EDT 2022
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Acta pharmacologica Sinica
Dong J,Zhang KJ,Li GC,Chen XR,Lin JJ,Li JW,Lv ZY,Deng ZZ,Dai J,Cao W,Jiang Q
Fri Jul 01 00:00:00 EDT 2022
Tanshinone IIA Regulates Keap1/Nrf2 Signal Pathway by Activating Sestrin2 to Restrain Pulmonary Fibrosis.
The American journal of Chinese medicine
Li H,Wu M,Guo C,Zhai R,Chen J
Thu Dec 29 00:00:00 EST 2022
Tanshinone IIA Regulates Keap1/Nrf2 Signal Pathway by Activating Sestrin2 to Restrain Pulmonary Fibrosis.
The American journal of Chinese medicine
Li H,Wu M,Guo C,Zhai R,Chen J
Thu Dec 29 00:00:00 EST 2022
A comparison study between dimethyl itaconate and dimethyl fumarate in electrophilicity, Nrf2 activation, and anti-inflammation in vitro.
Journal of Asian natural products research
Zhang Y,Zhou YJ,Tang JS,Lan JQ,Kang YY,Wu L,Peng Y
Wed Jun 01 00:00:00 EDT 2022
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Antioxidants (Basel, Switzerland)
Zhao H,Xian G,Zeng J,Zhong G,An D,Peng Y,Hu D,Lin Y,Li J,Su S,Ning Y,Xu D,Zeng Q
Mon Oct 24 00:00:00 EDT 2022
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Antioxidants (Basel, Switzerland)
Zhao H,Xian G,Zeng J,Zhong G,An D,Peng Y,Hu D,Lin Y,Li J,Su S,Ning Y,Xu D,Zeng Q
Mon Oct 24 00:00:00 EDT 2022
Novel 18β-glycyrrhetinic acid derivatives as a Two-in-One agent with potent antimicrobial and anti-inflammatory activity.
Bioorganic chemistry
Tu B,Liang J,Ou Y,Zhang X,Zheng W,Wu R,Gan L,Li D,Lu Y,Wu J,David Hong W,Zhang K,Wu P,Jin J,Wong WL
Sun May 01 00:00:00 EDT 2022
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens.
Theriogenology
Huang Z,Dai H,Jiang J,Ye N,Zhu S,Wei Q,Lv Z,Shi F
Tue Feb 01 00:00:00 EST 2022
Using Collagen Peptides From the Skin of Monkfish (Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling.
Frontiers in nutrition
Miao B,Zheng J,Zheng G,Tian X,Zhang W,Yuan F,Yang Z
Mon May 02 00:00:00 EDT 2022
NRF-2/HO-1 Pathway-Mediated SHOX2 Activation Is a Key Switch for Heart Rate Acceleration by Yixin-Fumai Granules.
Oxidative medicine and cellular longevity
Zhang H,Chen C,Liu Y,Ren L,Qi J,Yang Y,Chen W,Yao Y,Cai X,Liu Z,Hao M,Li L,Deng Z,Sun M,Lu Y,Chen K,Hou P
Fri Oct 07 00:00:00 EDT 2022
Fibroblast growth factor 9 attenuates sepsis-induced fulminant hepatitis in mice.
Amino acids
Li A,Li XM,Song CG,Xiao X,Yao WM,Tian HS
Fri Jul 01 00:00:00 EDT 2022
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Bioengineered
Zhou S,Li J,Zhang X,Xiong W
Sun May 01 00:00:00 EDT 2022
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Biological trace element research
Qin S,Wang R,Tang D,Qin S,Guo Y,Shi Z
Sun May 01 00:00:00 EDT 2022
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Journal of agricultural and food chemistry
Ding XQ,Jian TY,Gai YN,Niu GT,Liu Y,Meng XH,Li J,Lyu H,Ren BR,Chen J
Wed Mar 09 00:00:00 EST 2022
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Human & experimental toxicology
Du P,Zhang X,Luo K,Li Y,Fu C,Xiao J,Xiao Q
Mon Apr 04 00:00:00 EDT 2022
Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma.
Molecular therapy oncolytics
Tran PX,Inoue J,Harada H,Inazawa J
Thu Mar 17 00:00:00 EDT 2022
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
European journal of pharmacology
Zheng LY,Zou X,Wang YL,Zou M,Ma F,Wang N,Li JW,Wang MS,Hung HY,Wang Q
Wed Jan 05 00:00:00 EST 2022
Rhein regulates redox-mediated activation of NLRP3 inflammasomes in intestinal inflammation through macrophage-activated crosstalk.
British journal of pharmacology
Zhou Y,Gao C,Vong CT,Tao H,Li H,Wang S,Wang Y
Sun May 01 00:00:00 EDT 2022
Rhein regulates redox-mediated activation of NLRP3 inflammasomes in intestinal inflammation through macrophage-activated crosstalk.
British journal of pharmacology
Zhou Y,Gao C,Vong CT,Tao H,Li H,Wang S,Wang Y
Sun May 01 00:00:00 EDT 2022
Gankyrin and TIGAR cooperatively accelerate glucose metabolism toward the PPP and TCA cycle in hepatocellular carcinoma.
Cancer science
Yang C,Cui XW,Ding ZW,Jiang TY,Feng XF,Pan YF,Lin YK,Shang TY,Wang Q,Pan J,Wang J,Wang HY,Dong LW
Thu Dec 01 00:00:00 EST 2022
Gankyrin and TIGAR cooperatively accelerate glucose metabolism toward the PPP and TCA cycle in hepatocellular carcinoma.
Cancer science
Yang C,Cui XW,Ding ZW,Jiang TY,Feng XF,Pan YF,Lin YK,Shang TY,Wang Q,Pan J,Wang J,Wang HY,Dong LW
Thu Dec 01 00:00:00 EST 2022
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
ACS nano
Shen S,Cheng X,Zhou L,Zhao Y,Wang H,Zhang J,Sun X,Wang Y,Shu Y,Xu Y,Tao Y,Li M,Lu Z,Cai W,Nie G,Qiu W
Tue Nov 22 00:00:00 EST 2022
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
ACS nano
Shen S,Cheng X,Zhou L,Zhao Y,Wang H,Zhang J,Sun X,Wang Y,Shu Y,Xu Y,Tao Y,Li M,Lu Z,Cai W,Nie G,Qiu W
Tue Nov 22 00:00:00 EST 2022
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
ACS nano
Shen S,Cheng X,Zhou L,Zhao Y,Wang H,Zhang J,Sun X,Wang Y,Shu Y,Xu Y,Tao Y,Li M,Lu Z,Cai W,Nie G,Qiu W
Tue Nov 22 00:00:00 EST 2022
Chaperone-mediated autophagy degrades Keap1 and promotes Nrf2-mediated antioxidative response.
Aging cell
Zhu L,He S,Huang L,Ren D,Nie T,Tao K,Xia L,Lu F,Mao Z,Yang Q
Wed Jun 01 00:00:00 EDT 2022
Curcumin reduces oxidative stress and fat deposition in longissimus dorsi muscle of intrauterine growth-retarded finishing pigs.
Animal science journal = Nihon chikusan Gakkaiho
Zhang J,Yan E,Zhang L,Wang T,Wang C
Fri Jun 17 00:00:00 EDT 2022
Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy.
Antioxidants (Basel, Switzerland)
Ramos H,Bogdanov P,Huerta J,Deàs-Just A,Hernández C,Simó R
Thu Jul 21 00:00:00 EDT 2022
NMN ameliorated radiation induced damage in NRF2-deficient cell and mice via regulating SIRT6 and SIRT7.
Free radical biology & medicine
Zhao X,Zhang M,Wang J,Ji K,Wang Y,Sun X,Xu C,Wang Q,He N,Song H,Du L,Wang F,Huang H,Liu Y,Liu Q
Sun Nov 20 00:00:00 EST 2022
The Protective Effects of Apigenin Against Radiation-Induced Intestinal Injury.
Dose-response : a publication of International Hormesis Society
Liu D,Peng R,Chen Z,Yu H,Wang S,Dong S,Li W,Shao W,Dai J,Li F,Jiang Q,Sun W
Fri Jul 22 00:00:00 EDT 2022
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Cellular and molecular gastroenterology and hepatology
Huang S,Wang Y,Xie S,Lai Y,Mo C,Zeng T,Kuang S,Deng G,Zhou C,Chen Y,Huang S,Gao L,Lv Z
Thu May 19 00:00:00 EDT 2022
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Cellular and molecular gastroenterology and hepatology
Huang S,Wang Y,Xie S,Lai Y,Mo C,Zeng T,Kuang S,Deng G,Zhou C,Chen Y,Huang S,Gao L,Lv Z
Thu May 19 00:00:00 EDT 2022
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Frontiers in pharmacology
Li D,Zhao H,Xu P,Lin Q,Zhao T,Li C,Cui ZK,Tian G
Tue Aug 23 00:00:00 EDT 2022
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Frontiers in pharmacology
Li D,Zhao H,Xu P,Lin Q,Zhao T,Li C,Cui ZK,Tian G
Tue Aug 23 00:00:00 EDT 2022
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang D,He WJ,Zhang ZT,Shi JJ,Wang X,Gu WT,Chen ZQ,Xu YH,Chen YB,Wang SM
Sat Jan 01 00:00:00 EST 2022
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang D,He WJ,Zhang ZT,Shi JJ,Wang X,Gu WT,Chen ZQ,Xu YH,Chen YB,Wang SM
Sat Jan 01 00:00:00 EST 2022
G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes.
Genome biology
Li C,Yin Z,Xiao R,Huang B,Cui Y,Wang H,Xiang Y,Wang L,Lei L,Ye J,Li T,Zhong Y,Guo F,Xia Y,Fang P,Liang K
Thu Dec 15 00:00:00 EST 2022
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Journal of ethnopharmacology
Xu LT,Wang T,Fang KL,Zhao Y,Wang XN,Ren DM,Shen T
Sun Jan 30 00:00:00 EST 2022
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Nature communications
Zhou W,Wu WH,Si ZL,Liu HL,Wang H,Jiang H,Liu YF,Alolga RN,Chen C,Liu SJ,Bian XY,Shan JJ,Li J,Tan NH,Zhang ZH
Fri Oct 14 00:00:00 EDT 2022
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Cells
He D,Liu Y,Li J,Wang H,Ye B,He Y,Li Z,Gao X,Fu S,Liu D
Mon Sep 19 00:00:00 EDT 2022
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension.
Bioengineered
Sun Y,Wan W,Zhao X,Han X,Ye T,Chen X,Ran Q,Wang X,Liu X,Qu C,Shi S,Zhang C,Yang B
Fri Apr 01 00:00:00 EDT 2022
Plasma-activated medium induces ferroptosis by depleting FSP1 in human lung cancer cells.
Cell death & disease
Jo A,Bae JH,Yoon YJ,Chung TH,Lee EW,Kim YH,Joh HM,Chung JW
Mon Mar 07 00:00:00 EST 2022
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
ChemMedChem
Ye H,Ma Z,Liu L,Zhang T,Han Q,Xiang Z,Xia Y,Ke Y,Guan X,Shi Q,Ataullakhanov FI,Panteleev M
Fri Dec 16 00:00:00 EST 2022
Glucose Increases Hepatic Mitochondrial Antioxidant Enzyme Activities in Insulin Resistant Rats Following Chronic Angiotensin Receptor Blockade.
International journal of molecular sciences
Godoy-Lugo JA,Thorwald MA,Mendez DA,Rodriguez R,Nakano D,Nishiyama A,Ortiz RM
Sat Sep 17 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.
International journal of molecular sciences
Shi K,Xiao Y,Dong Y,Wang D,Xie Y,Tu J,Xu K,Zhou Z,Cao G,Liu Y
Sat Dec 17 00:00:00 EST 2022
Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.
International journal of molecular sciences
Shi K,Xiao Y,Dong Y,Wang D,Xie Y,Tu J,Xu K,Zhou Z,Cao G,Liu Y
Sat Dec 17 00:00:00 EST 2022
Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.
International journal of molecular sciences
Shi K,Xiao Y,Dong Y,Wang D,Xie Y,Tu J,Xu K,Zhou Z,Cao G,Liu Y
Sat Dec 17 00:00:00 EST 2022
Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.
International journal of molecular sciences
Shi K,Xiao Y,Dong Y,Wang D,Xie Y,Tu J,Xu K,Zhou Z,Cao G,Liu Y
Sat Dec 17 00:00:00 EST 2022
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
The Journal of toxicological sciences
Lyu Y,Ren XK,Guo CC,Li ZF,Zheng JP
Fri Dec 02 00:00:00 EST 2022
Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization.
Cell death & disease
Liu H,Zhao D,Li H,Zhang W,Lin Q,Wang X,Zheng S,Zhang L,Li L,Hu S,Hu Y
Mon Feb 21 00:00:00 EST 2022
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Antioxidants & redox signaling
Xun Y,Zhou P,Yang Y,Li C,Zhang J,Hu H,Qin B,Zhang Z,Wang Q,Lu Y,Wang S
Sat Jan 01 00:00:00 EST 2022
Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway.
Acta pharmacologica Sinica
Wu YX,Wang YY,Gao ZQ,Chen D,Liu G,Wan BB,Jiang FJ,Wei MX,Zuo J,Zhu J,Chen YQ,Qian F,Pang QF
Wed Dec 01 00:00:00 EST 2021
Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway.
Acta pharmacologica Sinica
Wu YX,Wang YY,Gao ZQ,Chen D,Liu G,Wan BB,Jiang FJ,Wei MX,Zuo J,Zhu J,Chen YQ,Qian F,Pang QF
Wed Dec 01 00:00:00 EST 2021
Protective effects of gastrodin pretreatment on mouse hepatic ischemia-reperfusion occurring through antioxidant and anti-apoptotic mechanisms.
Experimental and therapeutic medicine
Sun B,Jiang J,Zhu X,Yang D,Cui Z,Zhang Y,Zhang M,Qian Y,Liu R,Yang W
Sat May 01 00:00:00 EDT 2021
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Theranostics
Luo Q,Xian P,Wang T,Wu S,Sun T,Wang W,Wang B,Yang H,Yang Y,Wang H,Liu W,Long Q
Fri Jul 30 00:00:00 EDT 2021
Downregulated MicroRNA-327 Attenuates Oxidative Stress-Mediated Myocardial Ischemia Reperfusion Injury Through Regulating the FGF10/Akt/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Zheng T,Yang J,Zhang J,Yang C,Fan Z,Li Q,Zhai Y,Liu H,Yang J
Wed May 26 00:00:00 EDT 2021
Acupuncture Relieves Stress-Induced Depressive Behavior by Reducing Oxidative Stress and Neuroapoptosis in Rats.
Frontiers in behavioral neuroscience
Cheng WJ,Li P,Huang WY,Huang Y,Chen WJ,Chen YP,Shen JL,Chen JK,Long NS,Meng XJ
Sat Jan 22 00:00:00 EST 2022
Protective Effects of Fisetin on Hepatic Ischemia-reperfusion Injury Through Alleviation of Apoptosis and Oxidative Stress.
Archives of medical research
Li Z,Wang Y,Zhang Y,Wang X,Gao B,Li Y,Li R,Wang J
Mon Feb 01 00:00:00 EST 2021
Protective Effects of Fisetin on Hepatic Ischemia-reperfusion Injury Through Alleviation of Apoptosis and Oxidative Stress.
Archives of medical research
Li Z,Wang Y,Zhang Y,Wang X,Gao B,Li Y,Li R,Wang J
Mon Feb 01 00:00:00 EST 2021
Protective Effects of Fisetin on Hepatic Ischemia-reperfusion Injury Through Alleviation of Apoptosis and Oxidative Stress.
Archives of medical research
Li Z,Wang Y,Zhang Y,Wang X,Gao B,Li Y,Li R,Wang J
Mon Feb 01 00:00:00 EST 2021
Resveratrol sustains intestinal barrier integrity, improves antioxidant capacity, and alleviates inflammation in the jejunum of ducks exposed to acute heat stress.
Poultry science
Yang C,Luo P,Chen SJ,Deng ZC,Fu XL,Xu DN,Tian YB,Huang YM,Liu WJ
Mon Nov 01 00:00:00 EDT 2021
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
PPAR research
Zhang J,Cheng P,Dai W,Ji J,Wu L,Feng J,Wu J,Yu Q,Li J,Guo C
Sat Feb 20 00:00:00 EST 2021
The Potential Protective Effect and Possible Mechanism of Peptides from Oyster (Crassostrea hongkongensis) Hydrolysate on Triptolide-Induced Testis Injury in Male Mice.
Marine drugs
Zhang X,Peng Z,Zheng H,Zhang C,Lin H,Qin X
Sat Oct 09 00:00:00 EDT 2021
Induction of Mitosis Delay and Apoptosis by CDDO-TFEA in Glioblastoma Multiforme.
Frontiers in pharmacology
Tsai TH,Lieu AS,Huang TY,Kwan AL,Lin CL,Hsu YC
Sat Dec 04 00:00:00 EST 2021
Glutaredoxin 1 protects neurons from oxygen-glucose deprivation/reoxygenation (OGD/R)-induced apoptosis and oxidative stress via the modulation of GSK-3β/Nrf2 signaling.
Journal of bioenergetics and biomembranes
Qiu Z,Li X,Duan C,Li R,Han L
Sun Aug 01 00:00:00 EDT 2021
Regulatory effects of flavonoids luteolin on BDE-209-induced intestinal epithelial barrier damage in Caco-2 cell monolayer model.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yuan J,Che S,Ruan Z,Song L,Tang R,Zhang L
Thu Apr 01 00:00:00 EDT 2021
Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways.
Journal of ethnopharmacology
Sun S,Zhang J,Li H,Du Y,Li S,Li A,Suo X,Wang Y,Sun Q
Mon May 10 00:00:00 EDT 2021
Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway.
Current drug metabolism
Pang X,Tang C,Cao P,Zhou L,Chen X
Tue Mar 15 00:00:00 EDT 2022
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
Journal of cellular and molecular medicine
Dai JM,Guo WN,Tan YZ,Niu KW,Zhang JJ,Liu CL,Yang XM,Tao KS,Chen ZN,Dai JY
Tue Jun 01 00:00:00 EDT 2021
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
Journal of cellular and molecular medicine
Dai JM,Guo WN,Tan YZ,Niu KW,Zhang JJ,Liu CL,Yang XM,Tao KS,Chen ZN,Dai JY
Tue Jun 01 00:00:00 EDT 2021
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 EST 2021
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 EST 2021
Marine algal polysaccharides alleviate aflatoxin B1-induced bursa of Fabricius injury by regulating redox and apoptotic signaling pathway in broilers.
Poultry science
Guo Y,Balasubramanian B,Zhao ZH,Liu WC
Mon Feb 01 00:00:00 EST 2021
Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves renal fibrosis depending on Sirt1 in HG-induced GMCs and STZ-induced diabetic rats.
European journal of pharmacology
Yang G,Li Q,Peng J,Jin L,Zhu X,Zheng D,Zhang Y,Wang R,Song Y,Hu W,Xie X
Wed Dec 15 00:00:00 EST 2021
Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves renal fibrosis depending on Sirt1 in HG-induced GMCs and STZ-induced diabetic rats.
European journal of pharmacology
Yang G,Li Q,Peng J,Jin L,Zhu X,Zheng D,Zhang Y,Wang R,Song Y,Hu W,Xie X
Wed Dec 15 00:00:00 EST 2021
Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves renal fibrosis depending on Sirt1 in HG-induced GMCs and STZ-induced diabetic rats.
European journal of pharmacology
Yang G,Li Q,Peng J,Jin L,Zhu X,Zheng D,Zhang Y,Wang R,Song Y,Hu W,Xie X
Wed Dec 15 00:00:00 EST 2021
Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves renal fibrosis depending on Sirt1 in HG-induced GMCs and STZ-induced diabetic rats.
European journal of pharmacology
Yang G,Li Q,Peng J,Jin L,Zhu X,Zheng D,Zhang Y,Wang R,Song Y,Hu W,Xie X
Wed Dec 15 00:00:00 EST 2021
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Pharmaceutical biology
Feng Z,Wang C,Meng Q,Wu J,Sun H
Wed Dec 01 00:00:00 EST 2021
Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway.
Molecular medicine reports
Yang S,Zhang X,Zhang H,Lin X,Chen X,Zhang Y,Lin X,Huang L,Zhuge Q
Wed Sep 01 00:00:00 EDT 2021
PLK2 protects retinal ganglion cells from oxidative stress by potentiating Nrf2 signaling via GSK-3β.
Journal of biochemical and molecular toxicology
Fan Y,Wang J,He N,Feng H
Sun Aug 01 00:00:00 EDT 2021
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Cell biochemistry and biophysics
Lu D,Le Y,Ding J,Dou X,Mao W,Zhu J
Tue Jun 01 00:00:00 EDT 2021
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Cell biochemistry and biophysics
Lu D,Le Y,Ding J,Dou X,Mao W,Zhu J
Tue Jun 01 00:00:00 EDT 2021
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
American journal of cancer research
Lu J,Liu SY,Zhang J,Yang GM,Gao GB,Yu NN,Li YP,Li YX,Ma ZQ,Wang Y,Lu CH
Sat Aug 07 00:00:00 EDT 2021
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
American journal of cancer research
Lu J,Liu SY,Zhang J,Yang GM,Gao GB,Yu NN,Li YP,Li YX,Ma ZQ,Wang Y,Lu CH
Sat Aug 07 00:00:00 EDT 2021
CSNK2B contributes to colorectal cancer cell proliferation by activating the mTOR signaling.
Journal of cell communication and signaling
Yu S,Hu Q,Fan K,Yang C,Gao Y
Wed Sep 01 00:00:00 EDT 2021
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Molecular immunology
Yang M,Kuang M,Wang G,Ali I,Tang Y,Yang C,Li Y,Li L
Thu Jul 01 00:00:00 EDT 2021
Analysis by Metabolomics and Transcriptomics for the Energy Metabolism Disorder and the Aryl Hydrocarbon Receptor Activation in Male Reproduction of Mice and GC-2spd Cells Exposed to PM2.5.
Frontiers in endocrinology
Shi F,Zhang Z,Wang J,Wang Y,Deng J,Zeng Y,Zou P,Ling X,Han F,Liu J,Ao L,Cao J
Fri Mar 18 00:00:00 EDT 2022
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Journal of biochemical and molecular toxicology
Zhang Y,Sun J,Dong Y,Shen X,Zhang Z
Mon Mar 01 00:00:00 EST 2021
Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway.
Frontiers in cardiovascular medicine
Liao ZQ,Jiang YN,Su ZL,Bi HL,Li JT,Li CL,Yang XL,Zhang Y,Xie X
Tue Jan 25 00:00:00 EST 2022
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Journal of agricultural and food chemistry
Hu S,Chen Y,Zhao S,Sun K,Luo L,Zeng L
Wed Nov 17 00:00:00 EST 2021
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Journal of agricultural and food chemistry
Hu S,Chen Y,Zhao S,Sun K,Luo L,Zeng L
Wed Nov 17 00:00:00 EST 2021
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway.
Cell death & disease
Lv Z,Xu X,Sun Z,Yang YX,Guo H,Li J,Sun K,Wu R,Xu J,Jiang Q,Ikegawa S,Shi D
Tue May 18 00:00:00 EDT 2021
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway.
Cell death & disease
Lv Z,Xu X,Sun Z,Yang YX,Guo H,Li J,Sun K,Wu R,Xu J,Jiang Q,Ikegawa S,Shi D
Tue May 18 00:00:00 EDT 2021
Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2.5-induced oxidative stress via miR-155/FOXO3a pathway.
Ecotoxicology and environmental safety
Li J,Wang J,Li Y,Zhao P,Tian Y,Liu X,He H,Jia R
Wed Nov 10 00:00:00 EST 2021
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Human & experimental toxicology
Yang F,Chen R
Mon Nov 01 00:00:00 EDT 2021
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Phytochemistry
Song Z,Gao C,Jiang Q,Xu J,Xiong L,Liu K,Sun D,Li H,Chen L
Wed Dec 01 00:00:00 EST 2021
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Phytochemistry
Song Z,Gao C,Jiang Q,Xu J,Xiong L,Liu K,Sun D,Li H,Chen L
Wed Dec 01 00:00:00 EST 2021
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1.
Redox biology
Zhang J,Cui J,Zhao F,Yang L,Xu X,Shi Y,Wei B
Fri Oct 01 00:00:00 EDT 2021
Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs.
Redox biology
Senyuk V,Eskandari N,Jiang Y,Garcia-Varela R,Sundstrom R,Leanza L,Peruzzo R,Burkard M,Minshall RD,Gentile S
Wed Sep 01 00:00:00 EDT 2021
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
FEBS open bio
Huang Q,Ouyang DS,Liu Q
Sun Aug 01 00:00:00 EDT 2021
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
FEBS open bio
Huang Q,Ouyang DS,Liu Q
Sun Aug 01 00:00:00 EDT 2021
Ginkgo biloba delays light-induced photoreceptor degeneration through antioxidant and antiapoptotic properties.
Experimental and therapeutic medicine
Chudhary M,Zhang C,Song S,Ren X,Kong L
Tue Jun 01 00:00:00 EDT 2021
Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis.
Life sciences
Zhang J,Jiang D,Lin S,Cheng Y,Pan J,Ding W,Chen Y,Fan J
Thu Apr 01 00:00:00 EDT 2021
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Ecotoxicology and environmental safety
Hong Y,Zhou Y,Shen L,Wei Y,Long C,Fu Y,Wu H,Wang J,Wu Y,Wu S,Wei G
Mon Dec 20 00:00:00 EST 2021
Methylcobalamin Protects Melanocytes from H2O2-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway.
Drug design, development and therapy
An R,Li D,Dong Y,She Q,Zhou T,Nie X,Pan R,Deng Y
Wed Mar 02 00:00:00 EST 2022
Methylcobalamin Protects Melanocytes from H2O2-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway.
Drug design, development and therapy
An R,Li D,Dong Y,She Q,Zhou T,Nie X,Pan R,Deng Y
Wed Mar 02 00:00:00 EST 2022
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Journal of cellular and molecular medicine
Li X,Wang X,Miao L,Liu Y,Lin X,Guo Y,Yuan R,Tian H
Tue Jun 01 00:00:00 EDT 2021
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Journal of cellular and molecular medicine
Li X,Wang X,Miao L,Liu Y,Lin X,Guo Y,Yuan R,Tian H
Tue Jun 01 00:00:00 EDT 2021
ATF3 regulates oxidative stress and extracellular matrix degradation via p38/Nrf2 signaling pathway in pelvic organ prolapse.
Tissue & cell
Feng J,Li Y,Jin X,Gong R,Xia Z
Wed Dec 01 00:00:00 EST 2021
ATF3 regulates oxidative stress and extracellular matrix degradation via p38/Nrf2 signaling pathway in pelvic organ prolapse.
Tissue & cell
Feng J,Li Y,Jin X,Gong R,Xia Z
Wed Dec 01 00:00:00 EST 2021
Tanshinone I Inhibits Oxidative Stress-Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling.
Frontiers in pharmacology
Wu YT,Xie LP,Hua Y,Xu HL,Chen GH,Han X,Tan ZB,Fan HJ,Chen HM,Li J,Liu B,Zhou YC
Sat Jun 05 00:00:00 EDT 2021
Tanshinone I Inhibits Oxidative Stress-Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling.
Frontiers in pharmacology
Wu YT,Xie LP,Hua Y,Xu HL,Chen GH,Han X,Tan ZB,Fan HJ,Chen HM,Li J,Liu B,Zhou YC
Sat Jun 05 00:00:00 EDT 2021
Tanshinone I Inhibits Oxidative Stress-Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling.
Frontiers in pharmacology
Wu YT,Xie LP,Hua Y,Xu HL,Chen GH,Han X,Tan ZB,Fan HJ,Chen HM,Li J,Liu B,Zhou YC
Sat Jun 05 00:00:00 EDT 2021
Myricetin protects against H2 O2 -induced oxidative damage and apoptosis in bovine mammary epithelial cells.
Journal of cellular physiology
Kan X,Liu J,Chen Y,Guo W,Xu D,Cheng J,Cao Y,Yang Z,Fu S
Thu Apr 01 00:00:00 EDT 2021
Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters.
Theriogenology
Ye N,Lv Z,Dai H,Huang Z,Shi F
Fri Jan 01 00:00:00 EST 2021
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Experimental and therapeutic medicine
Qian C,Yang Q,Guo L,Zhu H,You X,Liu H,Sun Y
Mon Feb 01 00:00:00 EST 2021
Nicotinamide improves NAD+ levels to protect against acetaminophen-induced acute liver injury in mice.
Human & experimental toxicology
Xu J,Zhang L,Jiang R,Hu K,Hu D,Liao C,Jiang S,Yang Y,Huang J,Tang L,Li L
Mon Nov 01 00:00:00 EDT 2021
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
FEBS open bio
Wei N,Lu T,Yang L,Dong Y,Liu X
Sun Aug 01 00:00:00 EDT 2021
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Journal of experimental & clinical cancer research : CR
Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C
Tue Aug 24 00:00:00 EDT 2021
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Journal of experimental & clinical cancer research : CR
Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C
Tue Aug 24 00:00:00 EDT 2021
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Journal of experimental & clinical cancer research : CR
Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C
Tue Aug 24 00:00:00 EDT 2021
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Food & function
Xu Q,Fan Y,Loor JJ,Liang Y,Lv H,Sun X,Jia H,Xu C
Thu Jan 21 00:00:00 EST 2021
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
International journal of biological macromolecules
Liu C,Hua H,Zhu H,Cheng Y,Guo Y,Yao W,Qian H
Tue Aug 31 00:00:00 EDT 2021
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon May 17 00:00:00 EDT 2021
Sodium Propionate Enhances Nrf2-Mediated Protective Defense Against Oxidative Stress and Inflammation in Lipopolysaccharide-Induced Neonatal Mice.
Journal of inflammation research
Chen D,Gao ZQ,Wang YY,Wan BB,Liu G,Chen JL,Wu YX,Zhou Q,Jiang SY,Yu RQ,Pang QF
Thu Apr 21 00:00:00 EDT 2022
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis.
Journal of ethnopharmacology
Zhang M,Zhang T,Song C,Qu J,Gu Y,Liu S,Li H,Xiao W,Kong L,Sun Y,Lv W
Mon Jun 28 00:00:00 EDT 2021
The Protective Effects of Shengmai Formula Against Myocardial Injury Induced by Ultrafine Particulate Matter Exposure and Myocardial Ischemia are Mediated by the PI3K/AKT/p38 MAPK/Nrf2 Pathway.
Frontiers in pharmacology
Chen L,Guo Y,Qu S,Li K,Yang T,Yang Y,Zheng Z,Liu H,Wang X,Deng S,Zhang Y,Zhu X,Li Y
Fri Mar 26 00:00:00 EDT 2021
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cong L,Lei MY,Liu ZQ,Liu ZF,Ma Z,Liu K,Li J,Deng Y,Liu W,Xu B
Thu Jul 01 00:00:00 EDT 2021
Cordyceps acid alleviates lung cancer in nude mice.
Journal of biochemical and molecular toxicology
Wang J,Chen H,Li W,Shan L
Mon Mar 01 00:00:00 EST 2021
Cordyceps acid alleviates lung cancer in nude mice.
Journal of biochemical and molecular toxicology
Wang J,Chen H,Li W,Shan L
Mon Mar 01 00:00:00 EST 2021
MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.
Physiological research
Guo H,Wang Y,Jia W,Liu L
Wed Mar 17 00:00:00 EDT 2021
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
Ecotoxicology and environmental safety
Li S,Wang X,Xiao Y,Wang Y,Wan Y,Li X,Li Q,Tang X,Cai D,Ran B,Wu C
Fri Jan 15 00:00:00 EST 2021
Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice.
Frontiers in pharmacology
Jia Y,Li J,Liu P,Si M,Jin Y,Wang H,Ma D,Chu L
Tue Nov 02 00:00:00 EDT 2021
Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
Cartilage
Shen PC,Chou SH,Lu CC,Huang HT,Chien SH,Huang PJ,Liu ZM,Shih CL,Su SJ,Chen LM,Tien YC
Wed Dec 01 00:00:00 EST 2021
Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
Cartilage
Shen PC,Chou SH,Lu CC,Huang HT,Chien SH,Huang PJ,Liu ZM,Shih CL,Su SJ,Chen LM,Tien YC
Wed Dec 01 00:00:00 EST 2021
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Ecotoxicology and environmental safety
Zhang Y,Guo S,Wang S,Li X,Hou D,Li H,Wang L,Xu Y,Ma B,Wang H,Jiang X
Wed Sep 01 00:00:00 EDT 2021
The piperine derivative HJ105 inhibits Aβ1-42-induced neuroinflammation and oxidative damage via the Keap1-Nrf2-TXNIP axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang X,Zhi J,Leng H,Chen Y,Gao H,Ma J,Ji J,Hu Q
Thu Jul 01 00:00:00 EDT 2021
Melatonin Analogues Potently Inhibit MAO-B and Protect PC12 Cells against Oxidative Stress.
Antioxidants (Basel, Switzerland)
Elkamhawy A,Woo J,Gouda NA,Kim J,Nada H,Roh EJ,Park KD,Cho J,Lee K
Tue Oct 12 00:00:00 EDT 2021
Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.
Neuroreport
Liang J,Zhou X,Wang J,Fei ZY,Qin GC,Zhang DK,Zhou JY,Chen LX
Wed Jan 13 00:00:00 EST 2021
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang W,Chen H,Ding L,Gong J,Zhang M,Guo W,Xu P,Li S,Zhang Y
Sat May 01 00:00:00 EDT 2021
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Frontiers in nutrition
Zhang P,Han X,Zhang X,Zhu X
Sun May 30 00:00:00 EDT 2021
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Human & experimental toxicology
Liu X,Li M,Zhu J,Huang W,Song J
Thu Jul 01 00:00:00 EDT 2021
Melatonin Promotes In Vitro Maturation of Vitrified-Warmed Mouse Germinal Vesicle Oocytes, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway.
Animals : an open access journal from MDPI
Guo S,Yang J,Qin J,Qazi IH,Pan B,Zang S,Lv T,Deng S,Fang Y,Zhou G
Fri Aug 06 00:00:00 EDT 2021
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Oxidative medicine and cellular longevity
Lv D,Luo M,Cheng Z,Wang R,Yang X,Guo Y,Huang L,Li X,Huang B,Shen J,Luo S,Yan J
Mon Feb 07 00:00:00 EST 2022
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
International journal of molecular sciences
Zou Y,Chen Z,Sun C,Yang D,Zhou Z,Peng X,Zheng L,Tang C
Sun Oct 10 00:00:00 EDT 2021
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Drug design, development and therapy
Ma L,Wu F,Shao Q,Chen G,Xu L,Lu F
Mon Jan 10 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells.
Journal of pharmacological sciences
Tong J,Fang J,Zhu T,Xiang P,Shang J,Chen L,Zhao J,Wang Y,Tong L,Sun M
Wed Dec 01 00:00:00 EST 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease.
European journal of medicinal chemistry
Qu L,Ji L,Wang C,Luo H,Li S,Peng W,Yin F,Lu D,Liu X,Kong L,Wang X
Mon Jul 05 00:00:00 EDT 2021
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Experimental and therapeutic medicine
Zhang Z,Qin X,Wang Z,Li Y,Chen F,Chen R,Li C,Zhang W,Zhang M
Tue Jun 01 00:00:00 EDT 2021
Black raspberry (Rubus occidentalis) attenuates inflammatory markers and vascular endothelial dysfunction in Wistar rats fed a high-fat diet with fructose solution.
Journal of food biochemistry
Park SY,Jung H,Lin Z,Hwang KT,Kwak HK
Fri Oct 01 00:00:00 EDT 2021
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Ecotoxicology and environmental safety
Zhao G,Qi L,Wang Y,Li X,Li Q,Tang X,Wang X,Wu C
Fri Oct 01 00:00:00 EDT 2021
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Biochemical and biophysical research communications
Feng J,Xie L,Yu X,Liu C,Dong H,Lu W,Kong R
Fri Mar 12 00:00:00 EST 2021
Peptides Isolated from Yak Milk Residue Exert Antioxidant Effects through Nrf2 Signal Pathway.
Oxidative medicine and cellular longevity
Yang F,He X,Chen T,Liu J,Luo Z,Sun S,Qin D,Huang W,Tang Y,Liu C,Luo F
Fri Mar 04 00:00:00 EST 2022
Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Liu X,Xu Y,Cheng S,Zhou X,Zhou F,He P,Hu F,Zhang L,Chen Y,Jia Y
Tue Jul 27 00:00:00 EDT 2021
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Frontiers in pharmacology
Liu Y,Fu X,Chen Z,Luo T,Zhu C,Ji Y,Bian Z
Tue May 18 00:00:00 EDT 2021
Salvinorin A protects against methicillin resistant staphylococcus aureus-induced acute lung injury via Nrf2 pathway.
International immunopharmacology
Zeng S,Chen D,Liu G,Wu YX,Gao ZQ,Su Y,Yuan JN,Liu L,Shan JC,Pang QF,Zhu T
Fri Jan 01 00:00:00 EST 2021
Adenosine 5'-monophosphate-activated protein kinase ameliorates bovine adipocyte oxidative stress by inducing antioxidant responses and autophagy.
Journal of dairy science
Xu Q,Fan Y,Loor JJ,Liang Y,Sun X,Jia H,Zhao C,Xu C
Thu Apr 01 00:00:00 EDT 2021
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
Oxidative medicine and cellular longevity
Li X,Wang X,Miao L,Guo Y,Yuan R,Ren J,Huang Y,Tian H
Fri Jan 28 00:00:00 EST 2022
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
Oxidative medicine and cellular longevity
Li X,Wang X,Miao L,Guo Y,Yuan R,Ren J,Huang Y,Tian H
Fri Jan 28 00:00:00 EST 2022
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Toxicology and applied pharmacology
Wang Y,Wang HL,Xing GD,Qian Y,Zhong JF,Chen KL
Thu Apr 01 00:00:00 EDT 2021
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Toxicology and applied pharmacology
Wang Y,Wang HL,Xing GD,Qian Y,Zhong JF,Chen KL
Thu Apr 01 00:00:00 EDT 2021
Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ding B,Geng S,Hou X,Ma X,Xu H,Yang F,Liu K,Liang W,Ma G
Thu Aug 18 00:00:00 EDT 2022
Upregulation of Chemoresistance by Mg2+ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells.
Cells
Onuma S,Manabe A,Yoshino Y,Matsunaga T,Asai T,Ikari A
Wed May 12 00:00:00 EDT 2021
Protective effects of Nrf2 against sepsis-induced hepatic injury.
Life sciences
Li L,Zhang Q,Zhang X,Xu X,Wang X,Huang X,Wang T,Jiang Z,Xiao L,Zhang L,Sun L
Fri Oct 01 00:00:00 EDT 2021
Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell.
Frontiers in immunology
Xiong H,Chen Z,Lin B,Xie B,Liu X,Chen C,Li Z,Jia Y,Wu Z,Yang M,Jia Y,Wang L,Zhou J,Meng X
Mon Feb 21 00:00:00 EST 2022
Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage.
Acta pharmaceutica Sinica. B
Bakalarz D,Surmiak M,Yang X,Wójcik D,Korbut E,Śliwowski Z,Ginter G,Buszewicz G,Brzozowski T,Cieszkowski J,Głowacka U,Magierowska K,Pan Z,Wang B,Magierowski M
Mon Feb 01 00:00:00 EST 2021
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.
Cell reports. Medicine
Huang D,Chowdhury S,Wang H,Savage SR,Ivey RG,Kennedy JJ,Whiteaker JR,Lin C,Hou X,Oberg AL,Larson MC,Eskandari N,Delisi DA,Gentile S,Huntoon CJ,Voytovich UJ,Shire ZJ,Yu Q,Gygi SP,Hoofnagle AN,Herbert ZT,Lorentzen TD,Calinawan A,Karnitz LM,Weroha SJ,Kaufmann SH,Zhang B,Wang P,Birrer MJ,Paulovich AG
Tue Dec 21 00:00:00 EST 2021
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Free radical biology & medicine
Tocmo R,Le B,Heun A,van Pijkeren JP,Parkin K,Johnson JJ
Mon Feb 01 00:00:00 EST 2021
20-HETE synthesis inhibition attenuates traumatic brain injury-induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC-1α pathway: A translational study.
Cell proliferation
Cui W,Wu X,Shi Y,Guo W,Luo J,Liu H,Zheng L,Du Y,Wang P,Wang Q,Feng D,Ge S,Qu Y
Mon Feb 01 00:00:00 EST 2021
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Cell death discovery
Wang W,Zhai D,Bai Y,Xue K,Deng L,Ma L,Du T,Ye Z,Qu D,Xiang A,Chen G,Zhao Y,Wang L,Lu Z
Tue Mar 23 00:00:00 EDT 2021
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Cell death discovery
Wang W,Zhai D,Bai Y,Xue K,Deng L,Ma L,Du T,Ye Z,Qu D,Xiang A,Chen G,Zhao Y,Wang L,Lu Z
Tue Mar 23 00:00:00 EDT 2021
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Cellular & molecular biology letters
Deng S,Wu D,Li L,Li J,Xu Y
Thu Nov 18 00:00:00 EST 2021
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway.
Experimental & molecular medicine
Yu HF,Zheng LW,Yang ZQ,Wang YS,Wang TT,Yue ZP,Guo B
Wed Sep 01 00:00:00 EDT 2021
Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice.
Clinical and experimental hypertension (New York, N.Y. : 1993)
Farooqui Z,Mohammad RS,Lokhandwala MF,Banday AA
Wed Feb 17 00:00:00 EST 2021
Astragaloside IV inhibits adriamycin-induced cardiac ferroptosis by enhancing Nrf2 signaling.
Molecular and cellular biochemistry
Luo LF,Guan P,Qin LY,Wang JX,Wang N,Ji ES
Thu Jul 01 00:00:00 EDT 2021
Astragaloside IV inhibits adriamycin-induced cardiac ferroptosis by enhancing Nrf2 signaling.
Molecular and cellular biochemistry
Luo LF,Guan P,Qin LY,Wang JX,Wang N,Ji ES
Thu Jul 01 00:00:00 EDT 2021
SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production.
Frontiers in cell and developmental biology
Zhao X,Gao M,Liang J,Chen Y,Wang Y,Wang Y,Xiao Y,Zhao Z,Wan X,Jiang M,Luo X,Wang F,Sun X
Wed Mar 10 00:00:00 EST 2021
Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism.
Aging
Yin D,Jin G,He H,Zhou W,Fan Z,Gong C,Zhao J,Xiong H
Wed Sep 08 00:00:00 EDT 2021
Exosomal miR-27 negatively regulates ROS production and promotes granulosa cells apoptosis by targeting SPRY2 in OHSS.
Journal of cellular and molecular medicine
Liu K,Yang W,Hu M,Xie W,Huang J,Cui M,He X,Nie X
Thu Apr 01 00:00:00 EDT 2021
Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease.
Journal of advanced research
Bian Y,Chen Y,Wang X,Cui G,Ung COL,Lu JH,Cong W,Tang B,Lee SM
Wed Dec 01 00:00:00 EST 2021
Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase 1 Signaling Pathway in vitro Studies.
International journal of nanomedicine
Zou L,Cheng G,Xu C,Liu H,Wang Y,Li N,Fan X,Zhu C,Xia W
Fri Mar 26 00:00:00 EDT 2021
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Food chemistry
Wang Y,Jin R,Chen J,Cao J,Xiao J,Li X,Sun C
Wed Dec 15 00:00:00 EST 2021
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Journal of agricultural and food chemistry
Xing Y,Ren X,Li X,Sui L,Shi X,Sun Y,Quan C,Xiu Z,Dong Y
Wed Sep 01 00:00:00 EDT 2021
Temozolomide Drives Ferroptosis via a DMT1-Dependent Pathway in Glioblastoma Cells.
Yonsei medical journal
Song Q,Peng S,Sun Z,Heng X,Zhu X
Wed Sep 01 00:00:00 EDT 2021
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fan S,Liu X,Wang Y,Ren X,Liu Y,Dong Y,Fan Q,Wei J,Ma J,Yu A,Song R,Sui H,Shen M,Fang F,Xia Q,She G
Fri Oct 01 00:00:00 EDT 2021
Notoginsenoside R1 Protects Against High Glucose-Induced Cell Injury Through AMPK/Nrf2 and Downstream HO-1 Signaling.
Frontiers in cell and developmental biology
Du F,Huang H,Cao Y,Ran Y,Wu Q,Chen B
Tue Dec 21 00:00:00 EST 2021
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
Journal of agricultural and food chemistry
Zhang Q,Su G,Yang Q,Wei Z,Wang J,Zheng L,Zhao M
Wed Sep 15 00:00:00 EDT 2021
Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy.
Frontiers in pharmacology
Luo LF,Qin LY,Wang JX,Guan P,Wang N,Ji ES
Sat Jun 12 00:00:00 EDT 2021
Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy.
Frontiers in pharmacology
Luo LF,Qin LY,Wang JX,Guan P,Wang N,Ji ES
Sat Jun 12 00:00:00 EDT 2021
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer.
Cell death & disease
Yang J,Mo J,Dai J,Ye C,Cen W,Zheng X,Jiang L,Ye L
Sat Nov 13 00:00:00 EST 2021
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer.
Cell death & disease
Yang J,Mo J,Dai J,Ye C,Cen W,Zheng X,Jiang L,Ye L
Sat Nov 13 00:00:00 EST 2021
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer.
Cell death & disease
Yang J,Mo J,Dai J,Ye C,Cen W,Zheng X,Jiang L,Ye L
Sat Nov 13 00:00:00 EST 2021
Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer.
Cell death & disease
Yang J,Mo J,Dai J,Ye C,Cen W,Zheng X,Jiang L,Ye L
Sat Nov 13 00:00:00 EST 2021
Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction.
European journal of medicinal chemistry
Zhou W,Xu C,Dong G,Qiao H,Yang J,Liu H,Ding L,Sun K,Zhao W
Wed May 05 00:00:00 EDT 2021
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Frontiers in pharmacology
Zhang X,Zhang Y,Zhou M,Xie Y,Dong X,Bai F,Zhang J
Fri Feb 04 00:00:00 EST 2022
The role of Nrf2 pathway in alleviating fluorine-induced apoptosis by different selenium sources in the chicken duodenum and jejunum.
Ecotoxicology and environmental safety
Ju H,Chen S,Xue Y,Zhang X,Wang Y
Fri Aug 27 00:00:00 EDT 2021
Dimethyl fumarate ameliorates endotoxin-induced acute kidney injury against macrophage oxidative stress.
Renal failure
Zhou K,Xie M,Yi S,Tang Y,Luo H,Xiao Q,Xiao J,Li Y
Wed Dec 01 00:00:00 EST 2021
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Journal of orthopaedic translation
Yao X,Sun K,Yu S,Luo J,Guo J,Lin J,Wang G,Guo Z,Ye Y,Guo F
Mon Mar 01 00:00:00 EST 2021
GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway.
Oxidative medicine and cellular longevity
Zhu L,Chen D,Zhu Y,Pan T,Xia D,Cai T,Lin H,Lin J,Jin X,Wu F,Yu S,Zhu K,Xu L,Chen Y
Thu Mar 03 00:00:00 EST 2022
The novel nanocomplexes containing deoxycholic acid-grafted chitosan and oleanolic acid displays the hepatoprotective effect against CCl4-induced liver injury in vivo.
International journal of biological macromolecules
Xin C,Liu S,Qu H,Wang Z
Tue Aug 31 00:00:00 EDT 2021
Cynaropicrin Induces Cell Cycle Arrest and Apoptosis by Inhibiting PKM2 to Cause DNA Damage and Mitochondrial Fission in A549 Cells.
Journal of agricultural and food chemistry
Ding Z,Xi J,Zhong M,Chen F,Zhao H,Zhang B,Fang J
Wed Nov 17 00:00:00 EST 2021
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Molecules (Basel, Switzerland)
Bai Y,Wang W,Wang L,Ma L,Zhai D,Wang F,Shi R,Liu C,Xu Q,Chen G,Lu Z
Sat Jan 09 00:00:00 EST 2021
PSMD12 promotes glioma progression by upregulating the expression of Nrf2.
Annals of translational medicine
Wang Z,Li Z,Xu H,Liao Y,Sun C,Chen Y,Sheng M,Lan Q,Wang Z
Thu Apr 01 00:00:00 EDT 2021
PSMD12 promotes glioma progression by upregulating the expression of Nrf2.
Annals of translational medicine
Wang Z,Li Z,Xu H,Liao Y,Sun C,Chen Y,Sheng M,Lan Q,Wang Z
Thu Apr 01 00:00:00 EDT 2021
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Immunity, inflammation and disease
Chen G,Yang Z,Wen D,Guo J,Xiong Q,Li P,Zhao L,Wang J,Wu C,Dong L
Wed Sep 01 00:00:00 EDT 2021
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.
International immunopharmacology
Wu B,Wu Y,Fan C,Feng C,Wang H,Bai F,Zuo J,Tang W
Sat May 01 00:00:00 EDT 2021
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon Sep 13 00:00:00 EDT 2021
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Medical science monitor : international medical journal of experimental and clinical research
Pan H,Xu Y,Cai Q,Wu M,Ding M
Fri Jun 04 00:00:00 EDT 2021
Gambogic acid ameliorates high glucose- and palmitic acid-induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo.
Cell stress & chaperones
Chen J,Li L,Zhou Y,Zhang J,Chen L
Mon Mar 01 00:00:00 EST 2021
Betanin Prevents Experimental Abdominal Aortic Aneurysm Progression by Modulating the TLR4/NF-κB and Nrf2/HO-1 Pathways.
Biological & pharmaceutical bulletin
Qiu R,Chen S,Hua F,Bian S,Chen J,Li G,Wu X
Mon Jan 17 00:00:00 EST 2022
Betanin Prevents Experimental Abdominal Aortic Aneurysm Progression by Modulating the TLR4/NF-κB and Nrf2/HO-1 Pathways.
Biological & pharmaceutical bulletin
Qiu R,Chen S,Hua F,Bian S,Chen J,Li G,Wu X
Mon Jan 17 00:00:00 EST 2022
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
International immunopharmacology
Wen L,Yang QH,Ma XL,Li T,Xiao S,Sun CF
Fri Oct 01 00:00:00 EDT 2021
Caveolin-1 Alleviates Acetaminophen-Induced Fat Accumulation in Non-Alcoholic Fatty Liver Disease by Enhancing Hepatic Antioxidant Ability via Activating AMPK Pathway.
Frontiers in pharmacology
Wang J,Jiang W,Xin J,Xue W,Shi C,Wen J,Huang Y,Hu C
Tue Jul 27 00:00:00 EDT 2021
Oxidative stress in retrotrapezoid nucleus/parafacial respiratory group and impairment of central chemoreception in rat offspring exposed to maternal cigarette smoke.
Reproductive toxicology (Elmsford, N.Y.)
Lei F,Wang W,Fu Y,Wang J,Zheng Y
Mon Mar 01 00:00:00 EST 2021
Lack of Type I Interferon Signaling Ameliorates Respiratory Syncytial Virus-Induced Lung Inflammation and Restores Antioxidant Defenses.
Antioxidants (Basel, Switzerland)
Ansar M,Qu Y,Ivanciuc T,Garofalo RP,Casola A
Tue Dec 28 00:00:00 EST 2021
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Neurobiology of aging
Guo C,Zhang Y,Nie Q,Cao D,Wang X,Wan X,Liu M,Cui J,Sun J,Bai Y,Li L
Mon Feb 01 00:00:00 EST 2021
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Neurobiology of aging
Guo C,Zhang Y,Nie Q,Cao D,Wang X,Wan X,Liu M,Cui J,Sun J,Bai Y,Li L
Mon Feb 01 00:00:00 EST 2021
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Neurobiology of aging
Guo C,Zhang Y,Nie Q,Cao D,Wang X,Wan X,Liu M,Cui J,Sun J,Bai Y,Li L
Mon Feb 01 00:00:00 EST 2021
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Neurobiology of aging
Guo C,Zhang Y,Nie Q,Cao D,Wang X,Wan X,Liu M,Cui J,Sun J,Bai Y,Li L
Mon Feb 01 00:00:00 EST 2021
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Journal of agricultural and food chemistry
Hu S,Li S,Liu Y,Sun K,Luo L,Zeng L
Wed Sep 15 00:00:00 EDT 2021
Lupeol ameliorates LPS/D-GalN induced acute hepatic damage by suppressing inflammation and oxidative stress through TGFβ1-Nrf2 signal pathway.
Aging
Huang S,Mo C,Zeng T,Lai Y,Zhou C,Xie S,Chen L,Wang Y,Chen Y,Huang S,Gao L,Lv Z
Thu Mar 11 00:00:00 EST 2021
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sun K,Luo J,Jing X,Xiang W,Guo J,Yao X,Liang S,Guo F,Xu T
Fri Jan 01 00:00:00 EST 2021
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sun K,Luo J,Jing X,Xiang W,Guo J,Yao X,Liang S,Guo F,Xu T
Fri Jan 01 00:00:00 EST 2021
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sun K,Luo J,Jing X,Xiang W,Guo J,Yao X,Liang S,Guo F,Xu T
Fri Jan 01 00:00:00 EST 2021
Nicotinic Acid against Acetaminophen-Induced Hepatotoxicity via Sirt1/Nrf2 Antioxidative Pathway in Mice.
Journal of nutritional science and vitaminology
Hu D,Zhang L,Jiang R,Liao C,Xu J,Jiang S,Yang Y,Lin L,Huang J,Shen Y,Tang L,Li L
Tue Aug 31 00:00:00 EDT 2021
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Oxidative medicine and cellular longevity
Peng W,Wan L,Luo Z,Xie Y,Liu Y,Huang T,Lu H,Hu J
Mon Jan 31 00:00:00 EST 2022
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Oxidative medicine and cellular longevity
Peng W,Wan L,Luo Z,Xie Y,Liu Y,Huang T,Lu H,Hu J
Mon Jan 31 00:00:00 EST 2022
Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities.
Cells
Hori Y,Tsutsumi R,Nasu K,Boateng A,Ashikari Y,Sugiura M,Nakajima M,Kurauchi Y,Hisatsune A,Katsuki H,Seki T
Mon May 03 00:00:00 EDT 2021
Protective effect of cynaroside on sepsis-induced multiple organ injury through Nrf2/HO-1-dependent macrophage polarization.
European journal of pharmacology
Feng J,Liu Z,Chen H,Zhang M,Ma X,Han Q,Lu D,Wang C
Mon Nov 15 00:00:00 EST 2021
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2.
Oncogene
Meng C,Zhan J,Chen D,Shao G,Zhang H,Gu W,Luo J
Mon Mar 01 00:00:00 EST 2021
Improving protection effects of eucalyptol via carboxymethyl chitosan-coated lipid nanoparticles on hyperglycaemia-induced vascular endothelial injury in rats.
Journal of drug targeting
Peng J,Jiang Z,Wu G,Cai Z,Du Q,Tao L,Zhang Y,Chen Y,Shen X
Tue Jun 01 00:00:00 EDT 2021
Improving protection effects of eucalyptol via carboxymethyl chitosan-coated lipid nanoparticles on hyperglycaemia-induced vascular endothelial injury in rats.
Journal of drug targeting
Peng J,Jiang Z,Wu G,Cai Z,Du Q,Tao L,Zhang Y,Chen Y,Shen X
Tue Jun 01 00:00:00 EDT 2021
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Cell death & disease
Zhang C,Nie P,Zhou C,Hu Y,Duan S,Gu M,Jiang D,Wang Y,Deng Z,Chen J,Chen S,Wang L
Wed Feb 24 00:00:00 EST 2021
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Cell death & disease
Zhang C,Nie P,Zhou C,Hu Y,Duan S,Gu M,Jiang D,Wang Y,Deng Z,Chen J,Chen S,Wang L
Wed Feb 24 00:00:00 EST 2021
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
Cell and tissue research
Cui Q,Yan L
Mon Nov 01 00:00:00 EDT 2021
PKM2 Is a Potential Diagnostic and Therapeutic Target for Retinitis Pigmentosa.
Disease markers
Zhu P,Yang Q,Li G,Chang Q
Tue Mar 01 00:00:00 EST 2022
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.
Molecular medicine reports
Liu M,Zheng B,Liu P,Zhang J,Chu X,Dong C,Shi J,Liang Y,Chu L,Liu Y,Han X
Tue Jun 01 00:00:00 EDT 2021
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Frontiers in pharmacology
Zhang Y,Fu Y,Jiang T,Liu B,Sun H,Zhang Y,Fan B,Li X,Qin X,Zheng Q
Wed Dec 15 00:00:00 EST 2021
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Frontiers in pharmacology
Zhang Y,Fu Y,Jiang T,Liu B,Sun H,Zhang Y,Fan B,Li X,Qin X,Zheng Q
Wed Dec 15 00:00:00 EST 2021
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Nanotoxicology
Zhang L,Zou L,Jiang X,Cheng S,Zhang J,Qin X,Qin Z,Chen C,Zou Z
Sun Aug 01 00:00:00 EDT 2021
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death.
Nanotoxicology
Zhang L,Zou L,Jiang X,Cheng S,Zhang J,Qin X,Qin Z,Chen C,Zou Z
Sun Aug 01 00:00:00 EDT 2021
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
International immunopharmacology
Zhang L,Zhu T,He F,Li X
Wed Dec 01 00:00:00 EST 2021
Nrf2 Activation Attenuates Chronic Constriction Injury-Induced Neuropathic Pain via Induction of PGC-1α-Mediated Mitochondrial Biogenesis in the Spinal Cord.
Oxidative medicine and cellular longevity
Sun J,Li JY,Zhang LQ,Li DY,Wu JY,Gao SJ,Liu DQ,Zhou YQ,Mei W
Mon Feb 07 00:00:00 EST 2022
Nrf2 Activation Attenuates Chronic Constriction Injury-Induced Neuropathic Pain via Induction of PGC-1α-Mediated Mitochondrial Biogenesis in the Spinal Cord.
Oxidative medicine and cellular longevity
Sun J,Li JY,Zhang LQ,Li DY,Wu JY,Gao SJ,Liu DQ,Zhou YQ,Mei W
Mon Feb 07 00:00:00 EST 2022
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Cell death & disease
Kong L,Deng J,Zhou X,Cai B,Zhang B,Chen X,Chen Z,Wang W
Mon Oct 11 00:00:00 EDT 2021
The Time-Course of Antioxidant Irisin Activity: Role of the Nrf2/HO-1/HMGB1 Axis.
Antioxidants (Basel, Switzerland)
Mazur-Bialy AI,Pocheć E
Mon Jan 11 00:00:00 EST 2021
Zisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Han J,Shi G,Li W,Wang S,Bai J,Sun X,Xie Y,Sui F,Chen F,Jiang D
Sat Jan 30 00:00:00 EST 2021
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Frontiers in immunology
Liu S,Guo W,Jia Y,Ye B,Liu S,Fu S,Liu J,Hu G
Mon Feb 14 00:00:00 EST 2022
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Frontiers in immunology
Liu S,Guo W,Jia Y,Ye B,Liu S,Fu S,Liu J,Hu G
Mon Feb 14 00:00:00 EST 2022
Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Journal of agricultural and food chemistry
Wang X,Gao Y,Wang L,Yang D,Bu W,Gou L,Huang J,Duan X,Pan Y,Cao S,Gao Z,Cheng C,Feng Z,Xie J,Yao R
Wed Mar 10 00:00:00 EST 2021
Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Journal of agricultural and food chemistry
Wang X,Gao Y,Wang L,Yang D,Bu W,Gou L,Huang J,Duan X,Pan Y,Cao S,Gao Z,Cheng C,Feng Z,Xie J,Yao R
Wed Mar 10 00:00:00 EST 2021
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Journal of cell science
Li W,Liu C,Huang Z,Shi L,Zhong C,Zhou W,Meng P,Li Z,Wang S,Luo F,Yan J,Wu T
Thu Apr 15 00:00:00 EDT 2021
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Journal of cellular and molecular medicine
Li L,Cheng SQ,Guo W,Cai ZY,Sun YQ,Huang XX,Yang J,Ji J,Chen YY,Dong YF,Cheng H,Sun XL
Fri Oct 01 00:00:00 EDT 2021
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Journal of cellular and molecular medicine
Li L,Cheng SQ,Guo W,Cai ZY,Sun YQ,Huang XX,Yang J,Ji J,Chen YY,Dong YF,Cheng H,Sun XL
Fri Oct 01 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
H2S probe CPC inhibits autophagy and promotes apoptosis by inhibiting glutathionylation of Keap1 at Cys434.
Apoptosis : an international journal on programmed cell death
Li N,Wang J,Zang X,Wang Z,Zhang T,Zhao B,Miao J,Lin Z
Mon Feb 01 00:00:00 EST 2021
H2S probe CPC inhibits autophagy and promotes apoptosis by inhibiting glutathionylation of Keap1 at Cys434.
Apoptosis : an international journal on programmed cell death
Li N,Wang J,Zang X,Wang Z,Zhang T,Zhao B,Miao J,Lin Z
Mon Feb 01 00:00:00 EST 2021
Polyphenols from Penthorum chinense Pursh. Attenuates high glucose-induced vascular inflammation through directly interacting with Keap1 protein.
Journal of ethnopharmacology
Sun Y,He L,Wang W,Wang T,Hua W,Li T,Wang L,Gao T,Chen F,Tang L
Thu Mar 25 00:00:00 EDT 2021
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
International immunopharmacology
Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q
Mon Nov 01 00:00:00 EDT 2021
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.
Food & function
Luo M,Zheng LW,Wang YS,Huang JC,Yang ZQ,Yue ZP,Guo B
Mon Sep 20 00:00:00 EDT 2021
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation.
Redox biology
Sun J,Zhou C,Zhao Y,Zhang X,Chen W,Zhou Q,Hu B,Gao D,Raatz L,Wang Z,Nelson PJ,Jiang Y,Ren N,Bruns CJ,Zhou H
Sat May 01 00:00:00 EDT 2021
Increased lipid peroxidation by graphene quantum dots induces ferroptosis in macrophages.
NanoImpact
Shao Y,Wang L,Chen J,Hunag Y,Huang Y,Wang X,Zhou D,Zhang J,Wu W,Zhang Q,Li F,Xia X,Huang Y
Thu Jul 01 00:00:00 EDT 2021
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Cell proliferation
Xu Y,Sang W,Zhong Y,Xue S,Yang M,Wang C,Lu H,Huan R,Mao X,Zhu L,He C,Ma J
Wed Dec 01 00:00:00 EST 2021
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Cell proliferation
Xu Y,Sang W,Zhong Y,Xue S,Yang M,Wang C,Lu H,Huan R,Mao X,Zhu L,He C,Ma J
Wed Dec 01 00:00:00 EST 2021
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
BioMed research international
Wu R,Zuo W,Xu X,Bi L,Zhang C,Chen H,Liu H
Mon Oct 25 00:00:00 EDT 2021
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
BioMed research international
Wu R,Zuo W,Xu X,Bi L,Zhang C,Chen H,Liu H
Mon Oct 25 00:00:00 EDT 2021
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
BioMed research international
Wu R,Zuo W,Xu X,Bi L,Zhang C,Chen H,Liu H
Mon Oct 25 00:00:00 EDT 2021
Heme-Mediated Activation of the Nrf2/HO-1 Axis Attenuates Calcification of Valve Interstitial Cells.
Biomedicines
Balogh E,Chowdhury A,Ababneh H,Csiki DM,Tóth A,Jeney V
Thu Apr 15 00:00:00 EDT 2021
Exosomes are involved in total body irradiation-induced intestinal injury in mice.
Acta pharmacologica Sinica
Li H,Jiang M,Zhao SY,Zhang SQ,Lu L,He X,Feng GX,Wu X,Fan SJ
Thu Jul 01 00:00:00 EDT 2021
Lactoferrin Alleviates Acute Alcoholic Liver Injury by Improving Redox-Stress Response Capacity in Female C57BL/6J Mice.
Journal of agricultural and food chemistry
Li D,Hu Z,He Q,Guo Y,Chong Y,Xu J,Qin L
Wed Dec 15 00:00:00 EST 2021
Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways.
Journal of agricultural and food chemistry
Yuan J,Che S,Zhang L,Ruan Z
Wed Apr 14 00:00:00 EDT 2021
Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways.
Journal of agricultural and food chemistry
Yuan J,Che S,Zhang L,Ruan Z
Wed Apr 14 00:00:00 EDT 2021
A new ferroptosis inhibitor, isolated from Ajuga nipponensis, protects neuronal cells via activating NRF2-antioxidant response elements (AREs) pathway.
Bioorganic chemistry
Tan Q,Fang Y,Peng X,Zhou H,Xu J,Gu Q
Fri Oct 01 00:00:00 EDT 2021
Tolerable upper intake level of iron damages the liver of weaned piglets.
Journal of animal physiology and animal nutrition
Ding H,Zhao Y,Yu X,Chen L,Han J,Feng J
Thu Jul 01 00:00:00 EDT 2021
Daphnetin inhibits spinal glial activation via Nrf2/HO-1/NF-κB signaling pathway and attenuates CFA-induced inflammatory pain.
International immunopharmacology
Yang Y,Sheng Q,Nie Z,Liu L,Zhang W,Chen G,Ye F,Shi L,Lv Z,Xie J,Wang D
Wed Sep 01 00:00:00 EDT 2021
Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma.
Frontiers in oncology
Liu Q,Zhao S,Meng F,Wang H,Sun L,Li G,Gao F,Chen F
Tue Jun 29 00:00:00 EDT 2021
Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma.
Frontiers in oncology
Liu Q,Zhao S,Meng F,Wang H,Sun L,Li G,Gao F,Chen F
Tue Jun 29 00:00:00 EDT 2021
Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma.
Frontiers in oncology
Liu Q,Zhao S,Meng F,Wang H,Sun L,Li G,Gao F,Chen F
Tue Jun 29 00:00:00 EDT 2021
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis.
International immunopharmacology
Zhu Z,Hu R,Li J,Xing X,Chen J,Zhou Q,Sun J
Thu Jul 01 00:00:00 EDT 2021
RTA404, an Activator of Nrf2, Activates the Checkpoint Kinases and Induces Apoptosis through Intrinsic Apoptotic Pathway in Malignant Glioma.
Journal of clinical medicine
Tsai TH,Lieu AS,Huang TY,Kwan AL,Lin CL,Hsu YC
Wed Oct 20 00:00:00 EDT 2021
Baicalin-loaded macrophage-derived exosomes ameliorate ischemic brain injury via the antioxidative pathway.
Materials science & engineering. C, Materials for biological applications
Huang Z,Guo L,Huang L,Shi Y,Liang J,Zhao L
Thu Jul 01 00:00:00 EDT 2021
Sophoricoside attenuates lipopolysaccharide-induced acute lung injury by activating the AMPK/Nrf2 signaling axis.
International immunopharmacology
Wu YX,Zeng S,Wan BB,Wang YY,Sun HX,Liu G,Gao ZQ,Chen D,Chen YQ,Lu MD,Pang QF
Fri Jan 01 00:00:00 EST 2021
Sophoricoside attenuates lipopolysaccharide-induced acute lung injury by activating the AMPK/Nrf2 signaling axis.
International immunopharmacology
Wu YX,Zeng S,Wan BB,Wang YY,Sun HX,Liu G,Gao ZQ,Chen D,Chen YQ,Lu MD,Pang QF
Fri Jan 01 00:00:00 EST 2021
A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus.
Journal of neuroinflammation
Iwasa K,Yamamoto S,Yamashina K,Yagishita-Kyo N,Maruyama K,Awaji T,Takei Y,Hirasawa A,Yoshikawa K
Mon Dec 27 00:00:00 EST 2021
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
European journal of pharmacology
Chen Y,Wang J,Li J,Zhu J,Wang R,Xi Q,Wu H,Shi T,Chen W
Mon Nov 15 00:00:00 EST 2021
Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu P,Li J,Liu M,Zhang M,Xue Y,Zhang Y,Han X,Jing X,Chu L
Thu Jul 01 00:00:00 EDT 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 EDT 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 EDT 2021
RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
Molecular carcinogenesis
Hahm ER,Kim SH,Singh KB,Singh SV
Fri Jan 01 00:00:00 EST 2021
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Food & function
Liu XL,Zhao YC,Zhu HY,Wu M,Zheng YN,Yang M,Cheng ZQ,Ding CB,Liu WC
Mon Nov 29 00:00:00 EST 2021
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2.
Toxicology and applied pharmacology
Sun M,Guo M,Ma G,Zhang N,Pan F,Fan X,Wang R
Wed Sep 01 00:00:00 EDT 2021
Herbal Extract Mixture Modulates Intestinal Antioxidative Capacity and Microbiota in Weaning Piglets.
Frontiers in microbiology
Wang M,Huang H,Wang L,Yang H,He S,Liu F,Tu Q,He S
Fri Nov 03 00:00:00 EDT 2023
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Frontiers in nutrition
Li X,Gao M,Zhu S,Yin L,Zhang B,Qi Y,Zhao Y,Yu Y,Xu L
Tue Jun 15 00:00:00 EDT 2021
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Nature cell biology
Shi M,Huang XY,Ren XY,Wei XY,Ma Y,Lin ZZ,Liu DT,Song L,Zhao TJ,Li G,Yao L,Zhu M,Zhang C,Xie C,Wu Y,Wu HM,Fan LP,Ou J,Zhan YH,Lin SY,Lin SC
Mon Mar 01 00:00:00 EST 2021
Tert-Butylhydroquinone Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in Rat Chondrocytes.
Evidence-based complementary and alternative medicine : eCAM
Yang B,Huang H,He Q,Lu W,Zheng L,Cui L
Tue Dec 21 00:00:00 EST 2021
Sodium arsenite induces spatial learning and memory impairment associated with oxidative stress and activates the Nrf2/PPARγ pathway against oxidative injury in mice hippocampus.
Toxicology research
Xiong L,Huang J,Gao Y,Gao Y,Wu C,He S,Zou L,Yang D,Han Y,Yuan Q,Zheng Z,Hu G
Mon Mar 01 00:00:00 EST 2021
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Free radical biology & medicine
Zhang MH,Li J,Zhu XY,Zhang YQ,Ye ST,Leng YR,Yang T,Zhang H,Kong LY
Sat Feb 20 00:00:00 EST 2021
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Free radical biology & medicine
Zhang MH,Li J,Zhu XY,Zhang YQ,Ye ST,Leng YR,Yang T,Zhang H,Kong LY
Sat Feb 20 00:00:00 EST 2021
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Free radical biology & medicine
Zhang MH,Li J,Zhu XY,Zhang YQ,Ye ST,Leng YR,Yang T,Zhang H,Kong LY
Sat Feb 20 00:00:00 EST 2021
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress.
Free radical biology & medicine
Zhang MH,Li J,Zhu XY,Zhang YQ,Ye ST,Leng YR,Yang T,Zhang H,Kong LY
Sat Feb 20 00:00:00 EST 2021
MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway.
Bioengineered
Zhou X,Chen Z,Pei L,Sun J
Wed Dec 01 00:00:00 EST 2021
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
Journal of ethnopharmacology
Zhang H,Li L,Hao M,Chen K,Lu Y,Qi J,Chen W,Ren L,Cai X,Chen C,Liu Z,Zhao B,Li Z,Hou P
Wed Sep 15 00:00:00 EDT 2021
Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway.
BioMed research international
Liu H,Xu X,Wu R,Bi L,Zhang C,Chen H,Yang Y
Mon Oct 25 00:00:00 EDT 2021
Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway.
BioMed research international
Liu H,Xu X,Wu R,Bi L,Zhang C,Chen H,Yang Y
Mon Oct 25 00:00:00 EDT 2021
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia.
Bioorganic & medicinal chemistry
Yang GX,Sun JM,Zheng LL,Zhang L,Li J,Gan HX,Huang Y,Huang J,Diao XX,Tang Y,Wang R,Ma L
Sat May 01 00:00:00 EDT 2021
CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes.
Pharmacological research
Yang Y,Li J,Zhang L,Lin Z,Xiao H,Sun X,Zhang M,Liu P,Huang H
Fri Jan 01 00:00:00 EST 2021
CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes.
Pharmacological research
Yang Y,Li J,Zhang L,Lin Z,Xiao H,Sun X,Zhang M,Liu P,Huang H
Fri Jan 01 00:00:00 EST 2021
CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes.
Pharmacological research
Yang Y,Li J,Zhang L,Lin Z,Xiao H,Sun X,Zhang M,Liu P,Huang H
Fri Jan 01 00:00:00 EST 2021
Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo.
Chinese medicine
Liu Y,Zhou J,Luo Y,Li J,Shang L,Zhou F,Yang S
Mon Nov 29 00:00:00 EST 2021
A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH.
Life sciences
Zhou J,Zhao Y,Guo YJ,Zhao YS,Liu H,Ren J,Li JR,Ji ES
Thu Jul 01 00:00:00 EDT 2021
Klotho ameliorates diabetic nephropathy by activating Nrf2 signaling pathway in podocytes.
Biochemical and biophysical research communications
Xing L,Guo H,Meng S,Zhu B,Fang J,Huang J,Chen J,Wang Y,Wang L,Yao X,Wang H
Fri Jan 01 00:00:00 EST 2021
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Cell death & disease
Feng X,Jiang T,Yang C,Pang S,Ding Z,Hu H,Wang H,Dong L,Yang N
Fri Dec 17 00:00:00 EST 2021
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Cell death & disease
Feng X,Jiang T,Yang C,Pang S,Ding Z,Hu H,Wang H,Dong L,Yang N
Fri Dec 17 00:00:00 EST 2021
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Cell death & disease
Feng X,Jiang T,Yang C,Pang S,Ding Z,Hu H,Wang H,Dong L,Yang N
Fri Dec 17 00:00:00 EST 2021
Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse.
Archives of gynecology and obstetrics
Lin T,Ji Y,Zhao Y,Xia Z
Sat May 01 00:00:00 EDT 2021
Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse.
Archives of gynecology and obstetrics
Lin T,Ji Y,Zhao Y,Xia Z
Sat May 01 00:00:00 EDT 2021
Inhibition of Oxidative Stress and ALOX12 and NF-κB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury.
Antioxidants (Basel, Switzerland)
Dai C,Li H,Wang Y,Tang S,Velkov T,Shen J
Fri Jun 18 00:00:00 EDT 2021
Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
Proceedings of the National Academy of Sciences of the United States of America
Kawasaki T,Sugihara F,Fukushima K,Matsuki T,Nabeshima H,Machida T,Mitsui Y,Fujimura S,Sagawa R,Gaheun L,Kuniyoshi K,Tanaka H,Narazaki M,Kumanogoh A,Akira S,Satoh T
Tue Jun 29 00:00:00 EDT 2021
Gastric Electrical Pacing Reduces Apoptosis of Interstitial Cells of Cajal via Antioxidative Stress Effect Attributing to Phenotypic Polarization of M2 Macrophages in Diabetic Rats.
Oxidative medicine and cellular longevity
Wang H,Zhao K,Ba Y,Gao T,Shi N,Niu Q,Liu C,Chen Y
Thu May 20 00:00:00 EDT 2021
HIV-Tat and Cocaine Impact Brain Energy Metabolism: Redox Modification and Mitochondrial Biogenesis Influence NRF Transcription-Mediated Neurodegeneration.
Molecular neurobiology
Sivalingam K,Cirino TJ,McLaughlin JP,Samikkannu T
Mon Feb 01 00:00:00 EST 2021
Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing.
JBMR plus
do Monte FA,Ahuja N,Awad KR,Pan Z,Young S,Kim HK,Aswath P,Brotto M,Varanasi VG
Thu Apr 01 00:00:00 EDT 2021
Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.
Chemistry & biodiversity
Zhang K,Fang KL,Wang T,Xu LT,Zhao Y,Wang XN,Xiang L,Shen T
Mon Nov 01 00:00:00 EDT 2021
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Weng WT,Kuo PC,Brown DA,Scofield BA,Furnas D,Paraiso HC,Wang PY,Yu IC,Yen JH
Tue May 11 00:00:00 EDT 2021
(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.
Toxicology and applied pharmacology
Tian X,Xue Y,Xie G,Zhou Y,Xiao H,Ding F,Zhang M
Fri Oct 15 00:00:00 EDT 2021
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway.
Ecotoxicology and environmental safety
Ma Y,Li S,Ye S,Tang S,Hu D,Wei L,Xiao F
Fri Oct 15 00:00:00 EDT 2021
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway.
Ecotoxicology and environmental safety
Ma Y,Li S,Ye S,Tang S,Hu D,Wei L,Xiao F
Fri Oct 15 00:00:00 EDT 2021
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Aging
Yang RZ,Zheng HL,Xu WN,Zheng XF,Li B,Jiang LS,Jiang SD
Mon Feb 01 00:00:00 EST 2021
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
Environmental toxicology
Meng X,Zhang L,Han B,Zhang Z
Mon Nov 01 00:00:00 EDT 2021
The in vitro and in vivo study of oleanolic acid indole derivatives as novel anti-inflammatory agents: Synthesis, biological evaluation, and mechanistic analysis.
Bioorganic chemistry
Jin J,He H,Zhang X,Wu R,Gan L,Li D,Lu Y,Wu P,Wong WL,Zhang K
Sun Aug 01 00:00:00 EDT 2021
Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis.
Journal of inflammation research
Zhou W,Sha Y,Zeng J,Zhang X,Zhang A,Ge X
Fri Apr 29 00:00:00 EDT 2022
Effect of Chronic Stress Present in Fibroblasts Derived from Patients with a Sporadic Form of AD on Mitochondrial Function and Mitochondrial Turnover.
Antioxidants (Basel, Switzerland)
Drabik K,Malińska D,Piecyk K,Dębska-Vielhaber G,Vielhaber S,Duszyński J,Szczepanowska J
Thu Jun 10 00:00:00 EDT 2021
Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.
Poultry science
Dai H,Lv Z,Huang Z,Ye N,Li S,Jiang J,Cheng Y,Shi F
Wed Dec 01 00:00:00 EST 2021
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Free radical biology & medicine
Ma WQ,Sun XJ,Zhu Y,Liu NF
Mon Mar 01 00:00:00 EST 2021
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
International immunopharmacology
Zhu F,Shao J,Tian Y,Xu Z
Wed Dec 01 00:00:00 EST 2021
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Technology and health care : official journal of the European Society for Engineering and Medicine
Li Y,Chandra TP,Song X,Nie L,Liu M,Yi J,Zheng X,Chu C,Yang J
Wed Aug 18 00:00:00 EDT 2021
Knockdown of RREB1 inhibits cell proliferation via enhanced p16 expression in gastric cancer.
Cell cycle (Georgetown, Tex.)
Gao Q,Wu Y,Lu C,Kai W,Xie W,Wang Q,Wang L,Liu S,Pan Y
Wed Dec 01 00:00:00 EST 2021
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway.
Life sciences
Shu M,Lei W,Su S,Wen Y,Luo F,Zhao L,Chen L,Lu C,Zhou Z,Li Z
Thu Jul 15 00:00:00 EDT 2021
The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.
Ecotoxicology and environmental safety
Li S,Ma Y,Liang Y,Liang N,Ye S,Xiao F
Fri May 07 00:00:00 EDT 2021
Curcumin hinders PBDE-47-induced neutrophil extracellular traps release via Nrf2-associated ROS inhibition.
Ecotoxicology and environmental safety
Ye S,Li S,Ma Y,Hu D,Xiao F
Wed Dec 01 00:00:00 EST 2021
The role of transcription factor Ap1 in the activation of the Nrf2/ARE pathway through TET1 in diabetic nephropathy.
Cell biology international
Tan Y,Cao H,Li Q,Sun J
Sun Aug 01 00:00:00 EDT 2021
Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells.
Cancers
Kwok HH,Gao B,Chan KH,Ip MS,Minna JD,Lam DC
Mon Oct 25 00:00:00 EDT 2021
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Journal of agricultural and food chemistry
Jin M,Wei Y,Yu H,Ma X,Yan S,Zhao L,Ding L,Cheng J,Feng H
Wed Nov 10 00:00:00 EST 2021
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Journal of agricultural and food chemistry
Jin M,Wei Y,Yu H,Ma X,Yan S,Zhao L,Ding L,Cheng J,Feng H
Wed Nov 10 00:00:00 EST 2021
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Journal of agricultural and food chemistry
Jin M,Wei Y,Yu H,Ma X,Yan S,Zhao L,Ding L,Cheng J,Feng H
Wed Nov 10 00:00:00 EST 2021
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Journal of agricultural and food chemistry
Jin M,Wei Y,Yu H,Ma X,Yan S,Zhao L,Ding L,Cheng J,Feng H
Wed Nov 10 00:00:00 EST 2021
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
Oxidative medicine and cellular longevity
Pei Z,Wang X,Yang C,Dong M,Wang F
Mon Feb 28 00:00:00 EST 2022
Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway.
Ecotoxicology and environmental safety
Cao L,Zhao J,Ma L,Chen J,Xu J,Rahman SU,Feng S,Li Y,Wu J,Wang X
Wed Dec 01 00:00:00 EST 2021
Limonin Alleviates Non-alcoholic Fatty Liver Disease by Reducing Lipid Accumulation, Suppressing Inflammation and Oxidative Stress.
Frontiers in pharmacology
Li Y,Yang M,Lin H,Yan W,Deng G,Ye H,Shi H,Wu C,Ma G,Xu S,Tan Q,Gao Z,Gao L
Fri Jan 21 00:00:00 EST 2022
Limonin Alleviates Non-alcoholic Fatty Liver Disease by Reducing Lipid Accumulation, Suppressing Inflammation and Oxidative Stress.
Frontiers in pharmacology
Li Y,Yang M,Lin H,Yan W,Deng G,Ye H,Shi H,Wu C,Ma G,Xu S,Tan Q,Gao Z,Gao L
Fri Jan 21 00:00:00 EST 2022
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Toxicology
Liu Z,He Q,Liu Y,Zhang Y,Cui M,Peng H,Wang Y,Chen S,Li D,Chen L,Xiao Y,Chen W,Wang Q
Wed Jun 30 00:00:00 EDT 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Biochemical and biophysical research communications
Li X,Wang X,Miao L,Guo Y,Yuan R,Tian H
Fri Jun 04 00:00:00 EDT 2021
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Biochemical and biophysical research communications
Li X,Wang X,Miao L,Guo Y,Yuan R,Tian H
Fri Jun 04 00:00:00 EDT 2021
Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway.
Life sciences
Zhang H,Zhou L,Zhou Y,Wang L,Jiang W,Liu L,Yue S,Zheng P,Liu H
Mon Nov 15 00:00:00 EST 2021
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Free radical biology & medicine
Hong J,Shi Z,Li C,Ji X,Li S,Chen Y,Jiang G,Shi M,Wang W,Zhang Y,Hu B,Yan S
Sun Aug 01 00:00:00 EDT 2021
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Free radical biology & medicine
Hong J,Shi Z,Li C,Ji X,Li S,Chen Y,Jiang G,Shi M,Wang W,Zhang Y,Hu B,Yan S
Sun Aug 01 00:00:00 EDT 2021
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Free radical biology & medicine
Hong J,Shi Z,Li C,Ji X,Li S,Chen Y,Jiang G,Shi M,Wang W,Zhang Y,Hu B,Yan S
Sun Aug 01 00:00:00 EDT 2021
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
Toxicology
Xue H,Cao H,Xing C,Feng J,Zhang L,Zhang C,Hu G,Yang F
Thu Jul 01 00:00:00 EDT 2021
Carnosic acid protects against ferroptosis in PC12 cells exposed to erastin through activation of Nrf2 pathway.
Life sciences
Cheng J,Xu T,Xun C,Guo H,Cao R,Gao S,Sheng W
Mon Feb 01 00:00:00 EST 2021
Carnosic acid protects against ferroptosis in PC12 cells exposed to erastin through activation of Nrf2 pathway.
Life sciences
Cheng J,Xu T,Xun C,Guo H,Cao R,Gao S,Sheng W
Mon Feb 01 00:00:00 EST 2021
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells.
Brain research bulletin
Peng W,Zhu Z,Yang Y,Hou J,Lu J,Chen C,Liu F,Pi R
Wed Sep 01 00:00:00 EDT 2021
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells.
Brain research bulletin
Peng W,Zhu Z,Yang Y,Hou J,Lu J,Chen C,Liu F,Pi R
Wed Sep 01 00:00:00 EDT 2021
Nox2 Inhibition Regulates Stress Response and Mitigates Skeletal Muscle Fiber Atrophy during Simulated Microgravity.
International journal of molecular sciences
Lawler JM,Hord JM,Ryan P,Holly D,Janini Gomes M,Rodriguez D,Guzzoni V,Garcia-Villatoro E,Green C,Lee Y,Little S,Garcia M,Hill L,Brooks MC,Lawler MS,Keys N,Mohajeri A,Kamal KY
Tue Mar 23 00:00:00 EDT 2021
Immunomodulation effects of polyphenols from thinned peach treated by different drying methods on RAW264.7 cells through the NF-κB and Nrf2 pathways.
Food chemistry
Guo C,Bi J,Li X,Lyu J,Liu X,Wu X,Liu J
Mon Mar 15 00:00:00 EDT 2021
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Aging
Pei Z,Yang C,Guo Y,Dong M,Wang F
Tue Sep 14 00:00:00 EDT 2021
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Aging
Pei Z,Yang C,Guo Y,Dong M,Wang F
Tue Sep 14 00:00:00 EDT 2021
Protection of the enhanced Nrf2 deacetylation and its downstream transcriptional activity by SIRT1 in myocardial ischemia/reperfusion injury.
International journal of cardiology
Xu JJ,Cui J,Lin Q,Chen XY,Zhang J,Gao EH,Wei B,Zhao W
Mon Nov 01 00:00:00 EDT 2021
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Huang M,Wang Q,Long F,Di Y,Wang J,Zhun Zhu Y,Liu X
Sun Mar 01 00:00:00 EST 2020
p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation.
Journal of nanobiotechnology
Wu Y,Jin Y,Sun T,Zhu P,Li J,Zhang Q,Wang X,Jiang J,Chen G,Zhao X
Tue May 19 00:00:00 EDT 2020
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Cell death & disease
Liu H,Zhu Y,Gao Y,Qi D,Zhao L,Zhao L,Liu C,Tao T,Zhou C,Sun X,Guo F,Xiao J
Tue Feb 18 00:00:00 EST 2020
Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability.
Journal of medicinal chemistry
Lazzara PR,David BP,Ankireddy A,Richardson BG,Dye K,Ratia KM,Reddy SP,Moore TW
Thu Jun 25 00:00:00 EDT 2020
Effects of Launaea sarmentosa Extract on Lipopolysaccharide-Induced Inflammation via Suppression of NF-κB/MAPK Signaling and Nrf2 Activation.
Nutrients
Nguyen TQC,Binh TD,Kusunoki R,Pham TLA,Nguyen YDH,Nguyen TT,Kanaori K,Kamei K
Wed Aug 26 00:00:00 EDT 2020
Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.
Meat science
Cheng K,Yu C,Li Z,Li S,Yan E,Song Z,Zhang H,Zhang L,Wang T
Tue Dec 01 00:00:00 EST 2020
HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2.
International immunopharmacology
Yang X,Ji J,Liu C,Zhou M,Li H,Ye S,Hu Q
Mon Jun 01 00:00:00 EDT 2020
Codonopsis lanceolata polysaccharide CLPS alleviates high fat/high sucrose diet-induced insulin resistance via anti-oxidative stress.
International journal of biological macromolecules
Zhang Y,Wang H,Zhang L,Yuan Y,Yu D
Sat Feb 15 00:00:00 EST 2020
A novel danshensu derivative ameliorates experimental colitis by modulating NADPH oxidase 4-dependent NLRP3 inflammasome activation.
Journal of cellular and molecular medicine
Pan LL,Ren Z,Liu Y,Zhao Y,Li H,Pan X,Fang X,Liang W,Wang Y,Yang J,Sun J
Sun Nov 01 00:00:00 EDT 2020
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Drug design, development and therapy
Gao Z,Sui J,Fan R,Qu W,Dong X,Sun D
Mon Mar 29 00:00:00 EDT 2021
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Drug design, development and therapy
Gao Z,Sui J,Fan R,Qu W,Dong X,Sun D
Mon Mar 29 00:00:00 EDT 2021
Long noncoding RNA TUG1 regulates prostate cancer cell proliferation, invasion and migration via the Nrf2 signaling axis.
Pathology, research and practice
Yang G,Yin H,Lin F,Gao S,Zhan K,Tong H,Tang X,Pan Q,Gou X
Wed Apr 01 00:00:00 EDT 2020
Hydrogen gas protects against delayed encephalopathy after acute carbon monoxide poisoning in a rat model.
Neurological research
Shen M,Zheng Y,Zhu K,Cai Z,Liu W,Sun X,Liu J,Zhu D
Wed Jan 01 00:00:00 EST 2020
Curcumin-cyclodextrin/cellulose nanocrystals improve the phenotype of Charcot-Marie-Tooth-1A transgenic rats through the reduction of oxidative stress.
Free radical biology & medicine
Caillaud M,Msheik Z,Ndong-Ntoutoume GM,Vignaud L,Richard L,Favreau F,Faye PA,Sturtz F,Granet R,Vallat JM,Sol V,Desmoulière A,Billet F
Tue Dec 01 00:00:00 EST 2020
Astragalus polysaccharide alleviates cognitive impairment and β-amyloid accumulation in APP/PS1 mice via Nrf2 pathway.
Biochemical and biophysical research communications
Qin X,Hua J,Lin SJ,Zheng HT,Wang JJ,Li W,Ke JJ,Cai HB
Tue Oct 20 00:00:00 EDT 2020
Astragalus polysaccharide alleviates cognitive impairment and β-amyloid accumulation in APP/PS1 mice via Nrf2 pathway.
Biochemical and biophysical research communications
Qin X,Hua J,Lin SJ,Zheng HT,Wang JJ,Li W,Ke JJ,Cai HB
Tue Oct 20 00:00:00 EDT 2020
Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway.
Brain research bulletin
Gou Z,Su X,Hu X,Zhou Y,Huang L,Fan Y,Li J,Lu L
Thu Oct 01 00:00:00 EDT 2020
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
Nature communications
Castiglione GM,Xu Z,Zhou L,Duh EJ
Mon May 18 00:00:00 EDT 2020
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
Nature communications
Castiglione GM,Xu Z,Zhou L,Duh EJ
Mon May 18 00:00:00 EDT 2020
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
Nature communications
Castiglione GM,Xu Z,Zhou L,Duh EJ
Mon May 18 00:00:00 EDT 2020
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
Nature communications
Castiglione GM,Xu Z,Zhou L,Duh EJ
Mon May 18 00:00:00 EDT 2020
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
Nature communications
Castiglione GM,Xu Z,Zhou L,Duh EJ
Mon May 18 00:00:00 EDT 2020
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
Nature communications
Castiglione GM,Xu Z,Zhou L,Duh EJ
Mon May 18 00:00:00 EDT 2020
Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats.
Oncology reports
Li M,Liu P,Xue Y,Liang Y,Shi J,Han X,Zhang J,Chu X,Chu L
Sun Nov 01 00:00:00 EDT 2020
Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway.
Frontiers in pharmacology
Li C,Zhang S,Li L,Hu Q,Ji S
Fri Nov 13 00:00:00 EST 2020
Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway.
Frontiers in pharmacology
Li C,Zhang S,Li L,Hu Q,Ji S
Fri Nov 13 00:00:00 EST 2020
Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway.
Frontiers in pharmacology
Li C,Zhang S,Li L,Hu Q,Ji S
Fri Nov 13 00:00:00 EST 2020
Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway.
Frontiers in pharmacology
Li C,Zhang S,Li L,Hu Q,Ji S
Fri Nov 13 00:00:00 EST 2020
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
Nucleic acids research
Sun X,Wang Y,Ji K,Liu Y,Kong Y,Nie S,Li N,Hao J,Xie Y,Xu C,Du L,Liu Q
Fri Sep 18 00:00:00 EDT 2020
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest.
Nucleic acids research
Sun X,Wang Y,Ji K,Liu Y,Kong Y,Nie S,Li N,Hao J,Xie Y,Xu C,Du L,Liu Q
Fri Sep 18 00:00:00 EDT 2020
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Cell death & disease
Zhang W,Gong J,Ding L,Zhang Z,Pan X,Chen X,Guo W,Zhang X,Yang X,Peng G,Lin Y,Gao F,Li Y,Zhu X,Xuan A,Wang S,Sun X,Zhang Y,Xu P
Thu Oct 22 00:00:00 EDT 2020
Resveratrol protects against CIH-induced myocardial injury by targeting Nrf2 and blocking NLRP3 inflammasome activation.
Life sciences
Sun ZM,Guan P,Luo LF,Qin LY,Wang N,Zhao YS,Ji ES
Sun Mar 15 00:00:00 EDT 2020
Resveratrol protects against CIH-induced myocardial injury by targeting Nrf2 and blocking NLRP3 inflammasome activation.
Life sciences
Sun ZM,Guan P,Luo LF,Qin LY,Wang N,Zhao YS,Ji ES
Sun Mar 15 00:00:00 EDT 2020
Sestrin2 overexpression alleviates hydrogen peroxide-induced apoptosis and oxidative stress in retinal ganglion cells by enhancing Nrf2 activation via Keap1 downregulation.
Chemico-biological interactions
Fan Y,Xing Y,Xiong L,Wang J
Mon Jun 01 00:00:00 EDT 2020
Mechanisms and therapeutic implications of RTA 408, an activator of Nrf2, in subarachnoid hemorrhage-induced delayed cerebral vasospasm and secondary brain injury.
PloS one
Tsai TH,Lin SH,Wu CH,Tsai YC,Yang SF,Lin CL
Fri Dec 11 00:00:00 EST 2020
Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice.
Scientific reports
Tamatam CM,Reddy NM,Potteti HR,Ankireddy A,Noone PM,Yamamoto M,Kensler TW,Reddy SP
Wed Nov 04 00:00:00 EST 2020
Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Yi J,Zhu J,Wu J,Thompson CB,Jiang X
Tue Dec 08 00:00:00 EST 2020
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Frontiers in pharmacology
Hu J,Zhu Z,Ying H,Yao J,Ma H,Li L,Zhao Y
Sat Feb 06 00:00:00 EST 2021
Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis.
Frontiers in pharmacology
Ren S,Wei Y,Wang R,Wei S,Wen J,Yang T,Chen X,Wu S,Jing M,Li H,Wang M,Zhao Y
Thu Dec 17 00:00:00 EST 2020
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Food & function
Chen Z,Xiao J,Liu H,Yao K,Hou X,Cao Y,Liu X
Wed Sep 23 00:00:00 EDT 2020
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Cancer science
Yu YP,Cai LC,Wang XY,Cheng SY,Zhang DM,Jian WG,Wang TD,Yang JK,Yang KB,Zhang C
Fri May 01 00:00:00 EDT 2020
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Toxicology in vitro : an international journal published in association with BIBRA
Liang LY,Wang MM,Liu M,Zhao W,Wang X,Shi L,Zhu MJ,Zhao YL,Liu L,Maurya P,Wang Y
Sat Feb 01 00:00:00 EST 2020
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Toxicology in vitro : an international journal published in association with BIBRA
Liang LY,Wang MM,Liu M,Zhao W,Wang X,Shi L,Zhu MJ,Zhao YL,Liu L,Maurya P,Wang Y
Sat Feb 01 00:00:00 EST 2020
Sp4 controls constitutive expression of neuronal serine racemase and NF-E2-related factor-2 mediates its induction by valproic acid.
Biochimica et biophysica acta. Gene regulatory mechanisms
Zhang H,Lu J,Wu S
Tue Sep 01 00:00:00 EDT 2020
NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes.
Glia
Oksanen M,Hyötyläinen I,Trontti K,Rolova T,Wojciechowski S,Koskuvi M,Viitanen M,Levonen AL,Hovatta I,Roybon L,Lehtonen Š,Kanninen KM,Hämäläinen RH,Koistinaho J
Sun Mar 01 00:00:00 EST 2020
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jin W,Xue Y,Xue Y,Han X,Song Q,Zhang J,Li Z,Cheng J,Guan S,Sun S,Chu L
Mon Jun 01 00:00:00 EDT 2020
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Qi D,Liu H,Sun X,Luo D,Zhu M,Tao T,Gao C,Zhou C,Zhou W,Xiao J
Fri Feb 26 00:00:00 EST 2021
α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2.
Frontiers in pharmacology
Huang B,Liu J,Fu S,Zhang Y,Li Y,He D,Ran X,Yan X,Du J,Meng T,Gao X,Liu D
Mon Sep 28 00:00:00 EDT 2020
α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2.
Frontiers in pharmacology
Huang B,Liu J,Fu S,Zhang Y,Li Y,He D,Ran X,Yan X,Du J,Meng T,Gao X,Liu D
Mon Sep 28 00:00:00 EDT 2020
Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang X,Wang T,Yang Y,Li R,Chen Y,Li R,Jiang X,Wang L
Thu Oct 01 00:00:00 EDT 2020
Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang X,Wang T,Yang Y,Li R,Chen Y,Li R,Jiang X,Wang L
Thu Oct 01 00:00:00 EDT 2020
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Cell communication and signaling : CCS
Xu A,Yang Y,Shao Y,Wu M,Sun Y
Wed Jan 15 00:00:00 EST 2020
Protective effect of Liraglutide on diabetic retinal neurodegeneration via inhibiting oxidative stress and endoplasmic reticulum stress.
Neurochemistry international
Liu J,Wei L,Wang Z,Song S,Lin Z,Zhu J,Ren X,Kong L
Sat Feb 01 00:00:00 EST 2020
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Kuo PC,Weng WT,Scofield BA,Paraiso HC,Brown DA,Wang PY,Yu IC,Yen JH
Wed Apr 29 00:00:00 EDT 2020
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Journal of experimental & clinical cancer research : CR
Liu JZ,Hu YL,Feng Y,Jiang Y,Guo YB,Liu YF,Chen X,Yang JL,Chen YY,Mao QS,Xue WJ
Tue Jun 30 00:00:00 EDT 2020
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Journal of experimental & clinical cancer research : CR
Liu JZ,Hu YL,Feng Y,Jiang Y,Guo YB,Liu YF,Chen X,Yang JL,Chen YY,Mao QS,Xue WJ
Tue Jun 30 00:00:00 EDT 2020
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Journal of experimental & clinical cancer research : CR
Liu JZ,Hu YL,Feng Y,Jiang Y,Guo YB,Liu YF,Chen X,Yang JL,Chen YY,Mao QS,Xue WJ
Tue Jun 30 00:00:00 EDT 2020
Hylocereus polyrhizus Peel Extract Retards Alcoholic Liver Disease Progression by Modulating Oxidative Stress and Inflammatory Responses in C57BL/6 Mice.
Nutrients
Yeh WJ,Tsai CC,Ko J,Yang HY
Fri Dec 18 00:00:00 EST 2020
Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy.
British journal of pharmacology
Chen L,Liao F,Jiang Z,Zhang C,Wang Z,Luo P,Jiang Q,Wu J,Wang Q,Luo M,Li X,Leng Y,Ma L,Shen G,Chen Z,Wang Y,Tan X,Gan Y,Liu D,Liu Y,Shi C
Tue Sep 01 00:00:00 EDT 2020
Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy.
British journal of pharmacology
Chen L,Liao F,Jiang Z,Zhang C,Wang Z,Luo P,Jiang Q,Wu J,Wang Q,Luo M,Li X,Leng Y,Ma L,Shen G,Chen Z,Wang Y,Tan X,Gan Y,Liu D,Liu Y,Shi C
Tue Sep 01 00:00:00 EDT 2020
Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy.
British journal of pharmacology
Chen L,Liao F,Jiang Z,Zhang C,Wang Z,Luo P,Jiang Q,Wu J,Wang Q,Luo M,Li X,Leng Y,Ma L,Shen G,Chen Z,Wang Y,Tan X,Gan Y,Liu D,Liu Y,Shi C
Tue Sep 01 00:00:00 EDT 2020
Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy.
British journal of pharmacology
Chen L,Liao F,Jiang Z,Zhang C,Wang Z,Luo P,Jiang Q,Wu J,Wang Q,Luo M,Li X,Leng Y,Ma L,Shen G,Chen Z,Wang Y,Tan X,Gan Y,Liu D,Liu Y,Shi C
Tue Sep 01 00:00:00 EDT 2020
Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells.
Antioxidants (Basel, Switzerland)
Jasek-Gajda E,Jurkowska H,Jasińska M,Lis GJ
Fri Jul 17 00:00:00 EDT 2020
Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress.
European journal of pharmacology
Yu Z,Yang L,Deng S,Liang M
Thu Oct 15 00:00:00 EDT 2020
Effects of Compound Centella on Oxidative Stress and Keap1-Nrf2-ARE Pathway Expression in Diabetic Kidney Disease Rats.
Evidence-based complementary and alternative medicine : eCAM
Zhu Q,Zeng J,Li J,Chen X,Miao J,Jin Q,Chen H
Mon Sep 28 00:00:00 EDT 2020
Effects of Compound Centella on Oxidative Stress and Keap1-Nrf2-ARE Pathway Expression in Diabetic Kidney Disease Rats.
Evidence-based complementary and alternative medicine : eCAM
Zhu Q,Zeng J,Li J,Chen X,Miao J,Jin Q,Chen H
Mon Sep 28 00:00:00 EDT 2020
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Redox biology
Wang Y,Chen J,Li S,Zhang X,Guo Z,Hu J,Shao X,Song N,Zhao Y,Li H,Yang G,Xu C,Wei C
Fri May 01 00:00:00 EDT 2020
Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy.
Cell death & disease
Xu Q,Shi W,Lv P,Meng W,Mao G,Gong C,Chen Y,Wei Y,He X,Zhao J,Han H,Sun M,Xiao K
Thu Jan 02 00:00:00 EST 2020
Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy.
Cell death & disease
Xu Q,Shi W,Lv P,Meng W,Mao G,Gong C,Chen Y,Wei Y,He X,Zhao J,Han H,Sun M,Xiao K
Thu Jan 02 00:00:00 EST 2020
6-Gingerol ameliorates sepsis-induced liver injury through the Nrf2 pathway.
International immunopharmacology
Hong MK,Hu LL,Zhang YX,Xu YL,Liu XY,He PK,Jia YH
Sun Mar 01 00:00:00 EST 2020
MicroRNA-214-3p enhances erastin-induced ferroptosis by targeting ATF4 in hepatoma cells.
Journal of cellular physiology
Bai T,Liang R,Zhu R,Wang W,Zhou L,Sun Y
Wed Jul 01 00:00:00 EDT 2020
Cucurbitacin I induces apoptosis in ovarian cancer cells through oxidative stress and the p190B‑Rac1 signaling axis.
Molecular medicine reports
Li R,Xiao J,Tang S,Lin X,Xu H,Han B,Yang M,Liu F
Tue Sep 01 00:00:00 EDT 2020
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Oxidative medicine and cellular longevity
Qi J,Chen X,Wu Q,Wang J,Zhang H,Mao A,Zhu M,Miao C
Tue Nov 17 00:00:00 EST 2020
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Oxidative medicine and cellular longevity
Qi J,Chen X,Wu Q,Wang J,Zhang H,Mao A,Zhu M,Miao C
Tue Nov 17 00:00:00 EST 2020
MiR-23a-5p exacerbates intestinal ischemia-reperfusion injury by promoting oxidative stress via targeting PPAR alpha.
Biochemical pharmacology
Li LX,Yin LH,Gao M,Xu LN,Qi Y,Peng JY
Thu Oct 01 00:00:00 EDT 2020
Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Yao H,Sun J,Wei J,Zhang X,Chen B,Lin Y
Mon Sep 28 00:00:00 EDT 2020
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Andrologia
Zhou J,Xi Y,Zhang J,Tang J,Zhou X,Chen J,Nie C,Zhu Z,Ma B
Wed Apr 01 00:00:00 EDT 2020
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Andrologia
Zhou J,Xi Y,Zhang J,Tang J,Zhou X,Chen J,Nie C,Zhu Z,Ma B
Wed Apr 01 00:00:00 EDT 2020
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liang Y,Zheng B,Li J,Shi J,Chu L,Han X,Chu X,Zhang X,Zhang J
Sun Nov 01 00:00:00 EDT 2020
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
European journal of pharmacology
Wang J,Zhang X,Zhang L,Yan T,Wu B,Xu F,Jia Y
Sat Aug 15 00:00:00 EDT 2020
Polychlorinated biphenyl quinone induces hepatocytes iron overload through up-regulating hepcidin expression.
Environment international
Liu J,Tan Y,Yang B,Wu Y,Fan B,Zhu S,Song E,Song Y
Mon Jun 01 00:00:00 EDT 2020
Silibinin ameliorats H2O2-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells.
Acta histochemica
Guo H,Wang Y,Liu D
Tue Dec 01 00:00:00 EST 2020
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Stem cell research & therapy
Yao X,Yu S,Jing X,Guo J,Sun K,Guo F,Ye Y
Mon Mar 30 00:00:00 EDT 2020
Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.
Biochemical pharmacology
Cheng P,Liu H,Li Y,Pi P,Jiang Y,Zang S,Li X,Fu A,Ren X,Xu J,Holmgren A,Lu J
Fri May 01 00:00:00 EDT 2020
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.
Laboratory investigation; a journal of technical methods and pathology
Kong H,Wang H,Zhuo Z,Li Z,Tian P,Wu J,Liu J,Chen Z,Zhang J,Luo Q
Tue Sep 01 00:00:00 EDT 2020
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Pharmaceutical biology
Zhang X,Feng J,Su S,Huang L
Tue Dec 01 00:00:00 EST 2020
Dandelion Extract Alleviated Lipopolysaccharide-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
Toxins
Sun Y,Wu Y,Wang Z,Chen J,Yang Y,Dong G
Sat Aug 01 00:00:00 EDT 2020
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
Current eye research
Ren X,Sun L,Wei L,Liu J,Zhu J,Yu Q,Kong H,Kong L
Thu Oct 01 00:00:00 EDT 2020
Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway.
Animals : an open access journal from MDPI
Zhang L,Zhang J,Yan E,He J,Zhong X,Zhang L,Wang C,Wang T
Tue Mar 24 00:00:00 EDT 2020
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Wang Y,Li C,Li J,Wang G,Li L
Sun Jun 14 00:00:00 EDT 2020
Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway.
Biomolecules & therapeutics
Zhang X,Wang J,Gong G,Ma R,Xu F,Yan T,Wu B,Jia Y
Fri May 01 00:00:00 EDT 2020
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Cell death & disease
Ma WQ,Sun XJ,Zhu Y,Liu NF
Tue Nov 17 00:00:00 EST 2020
Sulforaphane reduces intracellular survival of Staphylococcus aureus in macrophages through inhibition of JNK and p38 MAPK‑induced inflammation.
International journal of molecular medicine
Deramaudt TB,Ali M,Vinit S,Bonay M
Mon Jun 01 00:00:00 EDT 2020
Metformin attenuates cardiac remodeling in mice through the Nrf2/Keap1 signaling pathway.
Experimental and therapeutic medicine
Du J,Zhu M,Li H,Liang G,Li Y,Feng S
Sat Aug 01 00:00:00 EDT 2020
Metformin attenuates cardiac remodeling in mice through the Nrf2/Keap1 signaling pathway.
Experimental and therapeutic medicine
Du J,Zhu M,Li H,Liang G,Li Y,Feng S
Sat Aug 01 00:00:00 EDT 2020
Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis.
Toxicology and applied pharmacology
Liu Z,Lv X,Song E,Song Y
Sun Nov 15 00:00:00 EST 2020
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Aging
Wang J,Li S,Wang J,Wu F,Chen Y,Zhang H,Guo Y,Lin Y,Li L,Yu X,Liu T,Zhao Y
Mon Jan 06 00:00:00 EST 2020
Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis.
Oncogene
Sun Q,Ye Z,Qin Y,Fan G,Ji S,Zhuo Q,Xu W,Liu W,Hu Q,Liu M,Zhang Z,Xu X,Yu X
Thu Oct 01 00:00:00 EDT 2020
Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis.
Oncogene
Sun Q,Ye Z,Qin Y,Fan G,Ji S,Zhuo Q,Xu W,Liu W,Hu Q,Liu M,Zhang Z,Xu X,Yu X
Thu Oct 01 00:00:00 EDT 2020
Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis.
Oncogene
Sun Q,Ye Z,Qin Y,Fan G,Ji S,Zhuo Q,Xu W,Liu W,Hu Q,Liu M,Zhang Z,Xu X,Yu X
Thu Oct 01 00:00:00 EDT 2020
Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes.
Cell metabolism
Carter CS,Huang SC,Searby CC,Cassaidy B,Miller MJ,Grzesik WJ,Piorczynski TB,Pak TK,Walsh SA,Acevedo M,Zhang Q,Mapuskar KA,Milne GL,Hinton AO,Guo DF,Weiss R,Bradberry K,Taylor EB,Rauckhorst AJ,Dick DW,Akurathi V,Falls-Hubert KC,Wagner BA,Carter WA,Wang K,Norris AW,Rahmouni K,Buettner GR,Hansen JM,Spitz DR,Abel ED,Sheffield VC
Tue Oct 06 00:00:00 EDT 2020
Luteolin alleviates ochratoxin A induced oxidative stress by regulating Nrf2 and HIF-1α pathways in NRK-52E rat kidney cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liu M,Cheng C,Li X,Zhou S,Hua J,Huang J,Li Y,Yang K,Zhang P,Zhang Y,Tian J
Wed Jul 01 00:00:00 EDT 2020
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Journal of medicinal food
Li H,Liang M,Wang Z,Zhang Y,Wu Q,Yang L
Mon Jun 01 00:00:00 EDT 2020
Exogenous Hydrogen Sulfide Regulates Mycoplasma pneumoniae Lipid-Associated Membrane Proteins to Induce Expression of Heme Oxygenase-1 and Proinflammatory Cytokines.
Inflammation
Hu X,Zeng W,You X,Ding W,Liu P,Chen L,Zeng Y,Zhu C
Mon Jun 01 00:00:00 EDT 2020
Piceatannol Ameliorates Hepatic Oxidative Damage and Mitochondrial Dysfunction of Weaned Piglets Challenged with Diquat.
Animals : an open access journal from MDPI
Jia P,Ji S,Zhang H,Chen Y,Wang T
Tue Jul 21 00:00:00 EDT 2020
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
Frontiers in immunology
Chen S,Ding R,Hu Z,Yin X,Xiao F,Zhang W,Yan S,Lv C
Mon Apr 12 00:00:00 EDT 2021
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Cell death & disease
Zhang Y,Zhao S,Fu Y,Yan L,Feng Y,Chen Y,Wu Y,Deng Y,Zhang G,Chen Z,Chen Y,Liu T
Tue Aug 18 00:00:00 EDT 2020
Polydatin ameliorates chemotherapy-induced cognitive impairment (chemobrain) by inhibiting oxidative stress, inflammatory response, and apoptosis in rats.
Bioscience, biotechnology, and biochemistry
Tong Y,Wang K,Sheng S,Cui J
Mon Jun 01 00:00:00 EDT 2020
Activating PPARγ Increases NQO1 and γ-GCS Expression via Nrf2 in Thrombin-activated Microglia.
Current medical science
Hang H,Wang LK,Ren SY,Song AJ,Wu GF
Sat Feb 01 00:00:00 EST 2020
Formononetin Attenuates Airway Inflammation and Oxidative Stress in Murine Allergic Asthma.
Frontiers in pharmacology
Yi L,Cui J,Wang W,Tang W,Teng F,Zhu X,Qin J,Wuniqiemu T,Sun J,Wei Y,Dong J
Tue Oct 06 00:00:00 EDT 2020
Cholestasis Differentially Affects Liver Connexins.
International journal of molecular sciences
Cooreman A,Van Campenhout R,Crespo Yanguas S,Gijbels E,Leroy K,Pieters A,Tabernilla A,Van Brantegem P,Annaert P,Cogliati B,Vinken M
Mon Sep 07 00:00:00 EDT 2020
NRF2 regulates the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via FOCAD-FAK signaling pathway.
Redox biology
Liu P,Wu D,Duan J,Xiao H,Zhou Y,Zhao L,Feng Y
Thu Oct 01 00:00:00 EDT 2020
NRF2 regulates the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via FOCAD-FAK signaling pathway.
Redox biology
Liu P,Wu D,Duan J,Xiao H,Zhou Y,Zhao L,Feng Y
Thu Oct 01 00:00:00 EDT 2020
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
Chemistry & biodiversity
Hao J,Ding Y,Shi W,Zhang C,Li R
Tue Dec 01 00:00:00 EST 2020
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
Chemistry & biodiversity
Hao J,Ding Y,Shi W,Zhang C,Li R
Tue Dec 01 00:00:00 EST 2020
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
Chemistry & biodiversity
Hao J,Ding Y,Shi W,Zhang C,Li R
Tue Dec 01 00:00:00 EST 2020
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
Chemistry & biodiversity
Hao J,Ding Y,Shi W,Zhang C,Li R
Tue Dec 01 00:00:00 EST 2020
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhang B,Yu D,Luo N,Yang C,Zhu Y
Tue Sep 01 00:00:00 EDT 2020
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhang B,Yu D,Luo N,Yang C,Zhu Y
Tue Sep 01 00:00:00 EDT 2020
Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2.
Journal of animal physiology and animal nutrition
Xu B,Zang SC,Lang LM,Lian S,Lu J,Li SZ,Yang HM,Zhen L
Sun Nov 01 00:00:00 EDT 2020
Autophagy Inhibition Enables Nrf2 to Exaggerate the Progression of Diabetic Cardiomyopathy in Mice.
Diabetes
Zang H,Wu W,Qi L,Tan W,Nagarkatti P,Nagarkatti M,Wang X,Cui T
Tue Dec 01 00:00:00 EST 2020
Syringin protects against colitis by ameliorating inflammation.
Archives of biochemistry and biophysics
Zhang H,Gu H,Jia Q,Zhao Y,Li H,Shen S,Liu X,Wang G,Shi Q
Sat Feb 15 00:00:00 EST 2020
Syringin protects against colitis by ameliorating inflammation.
Archives of biochemistry and biophysics
Zhang H,Gu H,Jia Q,Zhao Y,Li H,Shen S,Liu X,Wang G,Shi Q
Sat Feb 15 00:00:00 EST 2020
Syringin protects against colitis by ameliorating inflammation.
Archives of biochemistry and biophysics
Zhang H,Gu H,Jia Q,Zhao Y,Li H,Shen S,Liu X,Wang G,Shi Q
Sat Feb 15 00:00:00 EST 2020
Syringin protects against colitis by ameliorating inflammation.
Archives of biochemistry and biophysics
Zhang H,Gu H,Jia Q,Zhao Y,Li H,Shen S,Liu X,Wang G,Shi Q
Sat Feb 15 00:00:00 EST 2020
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
Drug design, development and therapy
Wang H,Jiang Z,Pang Z,Zhou T,Gu Y
Mon Aug 23 00:00:00 EDT 2021
Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling.
Frontiers in immunology
Lin Y,Luo T,Weng A,Huang X,Yao Y,Fu Z,Li Y,Liu A,Li X,Chen D,Pan H
Mon Jun 21 00:00:00 EDT 2021
Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling.
Frontiers in immunology
Lin Y,Luo T,Weng A,Huang X,Yao Y,Fu Z,Li Y,Liu A,Li X,Chen D,Pan H
Mon Jun 21 00:00:00 EDT 2021
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhu M,Liu H,Sun K,Liu J,Mou Y,Qi D,Zhou C,Abudunaibi M,Tasiken B,Li J,Cheng H,Huang H
Sun Mar 01 00:00:00 EST 2020
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Acta biochimica et biophysica Sinica
Chen X,Qi J,Wu Q,Jiang H,Wang J,Chen W,Mao A,Zhu M
Tue May 26 00:00:00 EDT 2020
TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway.
Nature communications
Liu Y,Tao S,Liao L,Li Y,Li H,Li Z,Lin L,Wan X,Yang X,Chen L
Fri Jan 17 00:00:00 EST 2020
TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway.
Nature communications
Liu Y,Tao S,Liao L,Li Y,Li H,Li Z,Lin L,Wan X,Yang X,Chen L
Fri Jan 17 00:00:00 EST 2020
Hesperidin ameliorates hypobaric hypoxia-induced retinal impairment through activation of Nrf2/HO-1 pathway and inhibition of apoptosis.
Scientific reports
Xin X,Li Y,Liu H
Tue Nov 10 00:00:00 EST 2020
Evaluation and Exploration of Potentially Bioactive Peptides in Casein Hydrolysates against Liver Oxidative Damage in STZ/HFD-Induced Diabetic Rats.
Journal of agricultural and food chemistry
Wang C,Zheng L,Su G,Zeng XA,Sun B,Zhao M
Wed Feb 26 00:00:00 EST 2020
Anti-Inflammatory Effects of Lasia spinosa Leaf Extract in Lipopolysaccharide-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
Nguyen TQC,Duy Binh T,Pham TLA,Nguyen YDH,Thi Xuan Trang D,Nguyen TT,Kanaori K,Kamei K
Wed May 13 00:00:00 EDT 2020
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-B Pathway.
The American journal of Chinese medicine
Wu J,Yang CL,Sha YK,Wu Y,Liu ZY,Yuan ZH,Sun ZL
Fri Sep 04 00:00:00 EDT 2020
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Oxidative medicine and cellular longevity
Feng LX,Zhao F,Liu Q,Peng JC,Duan XJ,Yan P,Wu X,Wang HS,Deng YH,Duan SB
Fri May 14 00:00:00 EDT 2021
Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.
Biology of reproduction
Qi L,Jiang J,Zhang J,Zhang L,Wang T
Fri Apr 24 00:00:00 EDT 2020
Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice.
BioMed research international
Du J,He W,Zhang C,Wu J,Li Z,Wang M,Feng S,Liang G
Mon Nov 23 00:00:00 EST 2020
The expression of p-p62 and nuclear Nrf2 in esophageal squamous cell carcinoma and association with radioresistance.
Thoracic cancer
Wang Z,Zhang J,Li M,Kong L,Yu J
Wed Jan 01 00:00:00 EST 2020
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Journal of natural products
Yang WJ,Chen XM,Wang SQ,Hu HX,Cheng XP,Xu LT,Ren DM,Wang XN,Zhao BB,Lou HX,Shen T
Fri Apr 24 00:00:00 EDT 2020
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Journal of natural products
Yang WJ,Chen XM,Wang SQ,Hu HX,Cheng XP,Xu LT,Ren DM,Wang XN,Zhao BB,Lou HX,Shen T
Fri Apr 24 00:00:00 EDT 2020
Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responses.
Scientific reports
Jiang Z,Fu L,Xu Y,Hu X,Yang H,Zhang Y,Luo H,Gan S,Tao L,Liang G,Shen X
Tue Apr 14 00:00:00 EDT 2020
Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responses.
Scientific reports
Jiang Z,Fu L,Xu Y,Hu X,Yang H,Zhang Y,Luo H,Gan S,Tao L,Liang G,Shen X
Tue Apr 14 00:00:00 EDT 2020
MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.
Cell biology international
Xiao T,Sun J,Xing Z,Xie F,Yang L,Ding W
Sun Mar 01 00:00:00 EST 2020
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
Oxidative medicine and cellular longevity
Jin M,Feng H,Wang Y,Yan S,Shen B,Li Z,Qin H,Wang Q,Li J,Liu G
Wed May 05 00:00:00 EDT 2021
TRIM16 protects human periodontal ligament stem cells from oxidative stress-induced damage via activation of PICOT.
Experimental cell research
Zhao Y,Liu H,Xi X,Chen S,Liu D
Tue Dec 01 00:00:00 EST 2020
Mesenchymal stromal cells ameliorate acute lung injury induced by LPS mainly through stanniocalcin-2 mediating macrophage polarization.
Annals of translational medicine
Lv H,Liu Q,Sun Y,Yi X,Wei X,Liu W,Zhang Q,Yi H,Chen G
Sun Mar 01 00:00:00 EST 2020
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Journal of food biochemistry
Wang Z,Cai L,Li H,Liang M,Zhang Y,Wu Q,Yang L
Fri May 01 00:00:00 EDT 2020
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine.
Antioxidants (Basel, Switzerland)
Liou SF,Nguyen TTN,Hsu JH,Sulistyowati E,Huang SE,Wu BN,Lin MC,Yeh JL
Tue Oct 06 00:00:00 EDT 2020
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Food & function
Gu M,Jin J,Ren C,Chen X,Gao W,Wang X,Wu Y,Tian N,Pan Z,Wu A,Zhou Y,Zhang X
Tue Dec 01 00:00:00 EST 2020
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Food & function
Gu M,Jin J,Ren C,Chen X,Gao W,Wang X,Wu Y,Tian N,Pan Z,Wu A,Zhou Y,Zhang X
Tue Dec 01 00:00:00 EST 2020
Nardosinanone N suppresses LPS-induced macrophage activation by modulating the Nrf2 pathway and mPGES-1.
Biochemical pharmacology
Lio CK,Luo JF,Shen XY,Dai Y,Machado J,Xie Y,Yao YD,Yu Y,Liu JX,Yao XS,Luo P,Zhou H
Sun Mar 01 00:00:00 EST 2020
Nardosinanone N suppresses LPS-induced macrophage activation by modulating the Nrf2 pathway and mPGES-1.
Biochemical pharmacology
Lio CK,Luo JF,Shen XY,Dai Y,Machado J,Xie Y,Yao YD,Yu Y,Liu JX,Yao XS,Luo P,Zhou H
Sun Mar 01 00:00:00 EST 2020
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Biomaterials
Wang T,Jian Z,Baskys A,Yang J,Li J,Guo H,Hei Y,Xian P,He Z,Li Z,Li N,Long Q
Thu Oct 01 00:00:00 EDT 2020
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Qi L,Jiang J,Zhang J,Zhang L,Wang T
Sat Feb 01 00:00:00 EST 2020
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Qi L,Jiang J,Zhang J,Zhang L,Wang T
Sat Feb 01 00:00:00 EST 2020
Antioxidant activity of selenium-enriched Chrysomyia megacephala (Fabricius) larvae powder and its impact on intestinal microflora in D-galactose induced aging mice.
BMC complementary medicine and therapies
Xie D,Jiang L,Lin Y,Liu Z
Thu Aug 27 00:00:00 EDT 2020
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Science translational medicine
Jiang TY,Pan YF,Wan ZH,Lin YK,Zhu B,Yuan ZG,Ma YH,Shi YY,Zeng TM,Dong LW,Tan YX,Wang HY
Wed Sep 23 00:00:00 EDT 2020
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Science translational medicine
Jiang TY,Pan YF,Wan ZH,Lin YK,Zhu B,Yuan ZG,Ma YH,Shi YY,Zeng TM,Dong LW,Tan YX,Wang HY
Wed Sep 23 00:00:00 EDT 2020
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Pharmaceutical biology
Sun S,Wang Y,Du Y,Sun Q,He L,Zhu E,Li J
Tue Dec 01 00:00:00 EST 2020
Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p.
Cell death & disease
Huang W,Shi G,Yong Z,Li J,Qiu J,Cao Y,Zhao Y,Yuan L
Mon Jul 06 00:00:00 EDT 2020
Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p.
Cell death & disease
Huang W,Shi G,Yong Z,Li J,Qiu J,Cao Y,Zhao Y,Yuan L
Mon Jul 06 00:00:00 EDT 2020
Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.
Journal of drug targeting
Wang M,Li C,Shi W
Wed Jul 01 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
Life sciences
Li Z,Lian Y,Wei R,Jin L,Cao H,Zhao T,Ma X,Zhong M,Gao Y,Zhang K
Tue Dec 01 00:00:00 EST 2020
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.
Cells
Magierowska K,Bakalarz D,Wójcik D,Korbut E,Danielak A,Głowacka U,Pajdo R,Buszewicz G,Ginter G,Surmiak M,Kwiecień S,Chmura A,Magierowski M,Brzozowski T
Tue May 12 00:00:00 EDT 2020
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.
Cells
Magierowska K,Bakalarz D,Wójcik D,Korbut E,Danielak A,Głowacka U,Pajdo R,Buszewicz G,Ginter G,Surmiak M,Kwiecień S,Chmura A,Magierowski M,Brzozowski T
Tue May 12 00:00:00 EDT 2020
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
Brain research
Wen J,Li X,Zheng S,Xiao Y
Thu Oct 15 00:00:00 EDT 2020
Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2.
Molecular neurobiology
Wang Y,Lian M,Zhou J,Wu S
Sun Nov 01 00:00:00 EDT 2020
Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2.
Molecular neurobiology
Wang Y,Lian M,Zhou J,Wu S
Sun Nov 01 00:00:00 EDT 2020
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Neural regeneration research
Xiong Y,Xin DQ,Hu Q,Wang LX,Qiu J,Yuan HT,Chu XL,Liu DX,Li G,Wang Z
Thu Oct 01 00:00:00 EDT 2020
PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhou YQ,Liu DQ,Chen SP,Chen N,Sun J,Wang XM,Li DY,Tian YK,Ye DW
Tue Sep 01 00:00:00 EDT 2020
Protective effect of apigenin on d-galactosamine/LPS-induced hepatocellular injury by increment of Nrf-2 nucleus translocation.
Naunyn-Schmiedeberg's archives of pharmacology
Zhou RJ,Zhao Y,Fan K,Xie ML
Mon Jun 01 00:00:00 EDT 2020
Neuroprotective Effect of Salvianolic Acid A against Diabetic Peripheral Neuropathy through Modulation of Nrf2.
Oxidative medicine and cellular longevity
Xu C,Hou B,He P,Ma P,Yang X,Yang X,Zhang L,Qiang G,Li W,Du G
Tue Nov 10 00:00:00 EST 2020
Neuroprotective Effect of Salvianolic Acid A against Diabetic Peripheral Neuropathy through Modulation of Nrf2.
Oxidative medicine and cellular longevity
Xu C,Hou B,He P,Ma P,Yang X,Yang X,Zhang L,Qiang G,Li W,Du G
Tue Nov 10 00:00:00 EST 2020
Anthocyanins decrease the internalization of TiO2 nanoparticles into 3D Caco-2 spheroids.
Food chemistry
Wang J,Zhang J,Li S,Huang C,Xie Y,Cao Y
Mon Nov 30 00:00:00 EST 2020
HIPK2 overexpression relieves hypoxia/reoxygenation-induced apoptosis and oxidative damage of cardiomyocytes through enhancement of the Nrf2/ARE signaling pathway.
Chemico-biological interactions
Dang X,Zhang R,Peng Z,Qin Y,Sun J,Niu Z,Pei H
Sat Jan 25 00:00:00 EST 2020
TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways.
Oxidative medicine and cellular longevity
Meng X,Zhang C,Guo Y,Han Y,Wang C,Chu H,Kong L,Ma H
Thu Feb 04 00:00:00 EST 2021
Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway.
Molecules (Basel, Switzerland)
Dong Y,Xing Y,Sun J,Sun W,Xu Y,Quan C
Thu Jan 30 00:00:00 EST 2020
Protective effect of astaxanthin against La2O3 nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yuan L,Qu Y,Li Q,An T,Chen Z,Chen Y,Deng X,Bai D
Thu Oct 01 00:00:00 EDT 2020
La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
International journal of nanomedicine
Yuan L,Li Q,Bai D,Shang X,Hu F,Chen Z,An T,Chen Y,Zhang X
Thu Jul 23 00:00:00 EDT 2020
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
Evidence-based complementary and alternative medicine : eCAM
Tian TT,Li QR,Gan SQ,Chang CR,Shen XC
Mon Sep 28 00:00:00 EDT 2020
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Oxidative medicine and cellular longevity
Deng X,Lin N,Fu J,Xu L,Luo H,Jin Y,Liu Y,Sun L,Su J
Tue Jun 08 00:00:00 EDT 2021
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Oxidative medicine and cellular longevity
Deng X,Lin N,Fu J,Xu L,Luo H,Jin Y,Liu Y,Sun L,Su J
Tue Jun 08 00:00:00 EDT 2021
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Oxidative medicine and cellular longevity
Deng X,Lin N,Fu J,Xu L,Luo H,Jin Y,Liu Y,Sun L,Su J
Tue Jun 08 00:00:00 EDT 2021
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
Free radical biology & medicine
Mo C,Xie S,Zhong W,Zeng T,Huang S,Lai Y,Deng G,Zhou C,Yan W,Chen Y,Huang S,Gao L,Lv Z
Fri Nov 20 00:00:00 EST 2020
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
Free radical biology & medicine
Mo C,Xie S,Zhong W,Zeng T,Huang S,Lai Y,Deng G,Zhou C,Yan W,Chen Y,Huang S,Gao L,Lv Z
Fri Nov 20 00:00:00 EST 2020
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
Free radical biology & medicine
Mo C,Xie S,Zhong W,Zeng T,Huang S,Lai Y,Deng G,Zhou C,Yan W,Chen Y,Huang S,Gao L,Lv Z
Fri Nov 20 00:00:00 EST 2020
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
Free radical biology & medicine
Mo C,Xie S,Zhong W,Zeng T,Huang S,Lai Y,Deng G,Zhou C,Yan W,Chen Y,Huang S,Gao L,Lv Z
Fri Nov 20 00:00:00 EST 2020
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Aging
Ding S,Ma N,Liu H,Tang M,Mei J
Tue Nov 24 00:00:00 EST 2020
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Aging
Ding S,Ma N,Liu H,Tang M,Mei J
Tue Nov 24 00:00:00 EST 2020
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Wang J,Fang Z,Song C,Kang H,Guo Q,Dong Y,Zhang Y,Peng R,Guan H,Li F
Mon Sep 28 00:00:00 EDT 2020
Effect of Quercetin on PC12 Alzheimer's Disease Cell Model Induced by Aβ 25-35 and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway.
BioMed research international
Yu X,Li Y,Mu X
Wed Feb 10 00:00:00 EST 2021
l-Arginine Inhibits Apoptosis of Ovine Intestinal Epithelial Cells through the l-Arginine-Nitric Oxide Pathway.
The Journal of nutrition
Zhang H,Zhao F,Peng A,Guo S,Wang M,Elsabagh M,Loor JJ,Wang H
Sat Aug 01 00:00:00 EDT 2020
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine
Shen B,Feng H,Cheng J,Li Z,Jin M,Zhao L,Wang Q,Qin H,Liu G
Fri May 01 00:00:00 EDT 2020
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine
Shen B,Feng H,Cheng J,Li Z,Jin M,Zhao L,Wang Q,Qin H,Liu G
Fri May 01 00:00:00 EDT 2020
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine
Shen B,Feng H,Cheng J,Li Z,Jin M,Zhao L,Wang Q,Qin H,Liu G
Fri May 01 00:00:00 EDT 2020
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine
Shen B,Feng H,Cheng J,Li Z,Jin M,Zhao L,Wang Q,Qin H,Liu G
Fri May 01 00:00:00 EDT 2020
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine
Shen B,Feng H,Cheng J,Li Z,Jin M,Zhao L,Wang Q,Qin H,Liu G
Fri May 01 00:00:00 EDT 2020
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine
Shen B,Feng H,Cheng J,Li Z,Jin M,Zhao L,Wang Q,Qin H,Liu G
Fri May 01 00:00:00 EDT 2020
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Journal of hazardous materials
Xie C,Ge M,Jin J,Xu H,Mao L,Geng S,Wu J,Zhu J,Li X,Zhong C
Wed Jul 15 00:00:00 EDT 2020
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Journal of hazardous materials
Xie C,Ge M,Jin J,Xu H,Mao L,Geng S,Wu J,Zhu J,Li X,Zhong C
Wed Jul 15 00:00:00 EDT 2020
Inhibition of the Keap1-Nrf2 protein-protein interaction protects retinal cells and ameliorates retinal ischemia-reperfusion injury.
Free radical biology & medicine
Hui Q,Karlstetter M,Xu Z,Yang J,Zhou L,Eilken HM,Terjung C,Cho H,Gong J,Lai MJ,Nassar K,Duh EJ
Wed Jan 01 00:00:00 EST 2020
Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling.
Frontiers in pharmacology
Liu D,Bai X,Ma W,Xin D,Chu X,Yuan H,Qiu J,Ke H,Yin S,Chen W,Wang Z
Mon Sep 28 00:00:00 EDT 2020
Comparative effectiveness of 4 natural and chemical activators of Nrf2 on inflammation, oxidative stress, macrophage polarization, and bactericidal activity in an in vitro macrophage infection model.
PloS one
Ali M,Bonay M,Vanhee V,Vinit S,Deramaudt TB
Mon Aug 31 00:00:00 EDT 2020
Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells.
Clinical science (London, England : 1979)
You R,Zhou W,Li Y,Zhang Y,Huang S,Jia Z,Zhang A
Fri Jun 26 00:00:00 EDT 2020
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Food & function
Lin Z,Fu C,Yan Z,Wu Y,Zhan J,Lou Z,Liao X,Pan J
Thu Mar 26 00:00:00 EDT 2020
Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.
Bioorganic chemistry
Wang CN,Sang MM,Gong SN,Yang JF,Cheng CY,Sun F
Sun Nov 01 00:00:00 EDT 2020
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Life sciences
Shopit A,Niu M,Wang H,Tang Z,Li X,Tesfaldet T,Ai J,Ahmad N,Al-Azab M,Tang Z
Sat Feb 01 00:00:00 EST 2020
Inhibition of ferroptosis attenuates busulfan-induced oligospermia in mice.
Toxicology
Zhao X,Liu Z,Gao J,Li H,Wang X,Li Y,Sun F
Wed Jul 01 00:00:00 EDT 2020
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer.
Molecular therapy. Nucleic acids
Yang Q,Li K,Huang X,Zhao C,Mei Y,Li X,Jiao L,Yang H
Fri Mar 06 00:00:00 EST 2020
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Virulence
You L,Chen J,Liu W,Xiang Q,Luo Z,Wang W,Xu W,Wu K,Zhang Q,Liu Y,Wu J
Tue Dec 01 00:00:00 EST 2020
Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study.
Molecules (Basel, Switzerland)
Terada K,Murata A,Toki E,Goto S,Yamakawa H,Setoguchi S,Watase D,Koga M,Takata J,Matsunaga K,Karube Y
Mon Sep 14 00:00:00 EDT 2020
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons.
Pharmacological research
Wang GQ,Zhang B,He XM,Li DD,Shi JS,Zhang F
Tue Jan 01 00:00:00 EST 2019
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons.
Pharmacological research
Wang GQ,Zhang B,He XM,Li DD,Shi JS,Zhang F
Tue Jan 01 00:00:00 EST 2019
Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Song Q,Zhang Y,Han X,Zhang Y,Zhang X,Gao Y,Zhang J,Chu L,Zhao S
Tue Jan 01 00:00:00 EST 2019
Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Song Q,Zhang Y,Han X,Zhang Y,Zhang X,Gao Y,Zhang J,Chu L,Zhao S
Tue Jan 01 00:00:00 EST 2019
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Molecular nutrition & food research
Lei P,Tian S,Teng C,Huang L,Liu X,Wang J,Zhang Y,Li B,Shan Y
Fri Feb 01 00:00:00 EST 2019
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Molecular nutrition & food research
Lei P,Tian S,Teng C,Huang L,Liu X,Wang J,Zhang Y,Li B,Shan Y
Fri Feb 01 00:00:00 EST 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2-like 2 (NFE2L2) protein and the Smad2/3 pathway.
Journal of cellular physiology
Zhong L,Hao H,Chen D,Hou Q,Zhu Z,He W,Sun S,Sun M,Li M,Fu X
Fri Mar 01 00:00:00 EST 2019
Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2-like 2 (NFE2L2) protein and the Smad2/3 pathway.
Journal of cellular physiology
Zhong L,Hao H,Chen D,Hou Q,Zhu Z,He W,Sun S,Sun M,Li M,Fu X
Fri Mar 01 00:00:00 EST 2019
Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem Cells.
Stem cells (Dayton, Ohio)
Zuo R,Wang Y,Li J,Wu J,Wang W,Li B,Sun C,Wang Z,Shi C,Zhou Y,Liu M,Zhang C
Sat Jun 01 00:00:00 EDT 2019
Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem Cells.
Stem cells (Dayton, Ohio)
Zuo R,Wang Y,Li J,Wu J,Wang W,Li B,Sun C,Wang Z,Shi C,Zhou Y,Liu M,Zhang C
Sat Jun 01 00:00:00 EDT 2019
Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem Cells.
Stem cells (Dayton, Ohio)
Zuo R,Wang Y,Li J,Wu J,Wang W,Li B,Sun C,Wang Z,Shi C,Zhou Y,Liu M,Zhang C
Sat Jun 01 00:00:00 EDT 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Toxicology
Huang J,Lu Y,Zhang B,Yang S,Zhang Q,Cui H,Lu X,Zhao Y,Yang X,Li R
Tue Jan 15 00:00:00 EST 2019
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Toxicology
Huang J,Lu Y,Zhang B,Yang S,Zhang Q,Cui H,Lu X,Zhao Y,Yang X,Li R
Tue Jan 15 00:00:00 EST 2019
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Journal of cellular biochemistry
Li Y,Chen Y,Qiu C,Ma X,Lei K,Cai G,Liang X,Liu J
Fri Feb 01 00:00:00 EST 2019
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Journal of cellular biochemistry
Li Y,Chen Y,Qiu C,Ma X,Lei K,Cai G,Liang X,Liu J
Fri Feb 01 00:00:00 EST 2019
Differential response to lead toxicity in rat primary microglia and astrocytes.
Toxicology and applied pharmacology
Peng J,Zhou F,Wang Y,Xu Y,Zhang H,Zou F,Meng X
Tue Jan 15 00:00:00 EST 2019
Differential response to lead toxicity in rat primary microglia and astrocytes.
Toxicology and applied pharmacology
Peng J,Zhou F,Wang Y,Xu Y,Zhang H,Zou F,Meng X
Tue Jan 15 00:00:00 EST 2019
Differential response to lead toxicity in rat primary microglia and astrocytes.
Toxicology and applied pharmacology
Peng J,Zhou F,Wang Y,Xu Y,Zhang H,Zou F,Meng X
Tue Jan 15 00:00:00 EST 2019
Differential response to lead toxicity in rat primary microglia and astrocytes.
Toxicology and applied pharmacology
Peng J,Zhou F,Wang Y,Xu Y,Zhang H,Zou F,Meng X
Tue Jan 15 00:00:00 EST 2019
Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor.
Toxicology and applied pharmacology
Sha J,Zhang H,Zhao Y,Feng X,Hu X,Wang C,Song M,Fan H
Fri Feb 01 00:00:00 EST 2019
Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor.
Toxicology and applied pharmacology
Sha J,Zhang H,Zhao Y,Feng X,Hu X,Wang C,Song M,Fan H
Fri Feb 01 00:00:00 EST 2019
Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor.
Toxicology and applied pharmacology
Sha J,Zhang H,Zhao Y,Feng X,Hu X,Wang C,Song M,Fan H
Fri Feb 01 00:00:00 EST 2019
Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor.
Toxicology and applied pharmacology
Sha J,Zhang H,Zhao Y,Feng X,Hu X,Wang C,Song M,Fan H
Fri Feb 01 00:00:00 EST 2019
Electroacupuncture at ST-36 ameliorates DSS-induced acute colitis via regulating macrophage polarization induced by suppressing NLRP3/IL-1β and promoting Nrf2/HO-1.
Molecular immunology
Song S,An J,Li Y,Liu S
Fri Feb 01 00:00:00 EST 2019
Electroacupuncture at ST-36 ameliorates DSS-induced acute colitis via regulating macrophage polarization induced by suppressing NLRP3/IL-1β and promoting Nrf2/HO-1.
Molecular immunology
Song S,An J,Li Y,Liu S
Fri Feb 01 00:00:00 EST 2019
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Metabolic brain disease
Gao W,Wang W,Liu G,Zhang J,Yang J,Deng Z
Fri Feb 01 00:00:00 EST 2019
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Metabolic brain disease
Gao W,Wang W,Liu G,Zhang J,Yang J,Deng Z
Fri Feb 01 00:00:00 EST 2019
N-acetylcysteine alleviates fluoride-induced testicular apoptosis by modulating IRE1α/JNK signaling and nuclear Nrf2 activation.
Reproductive toxicology (Elmsford, N.Y.)
Hu Y,Wang Y,Yan T,Feng D,Ba Y,Zhang H,Zhu J,Cheng X,Cui L,Huang H
Fri Mar 01 00:00:00 EST 2019
N-acetylcysteine alleviates fluoride-induced testicular apoptosis by modulating IRE1α/JNK signaling and nuclear Nrf2 activation.
Reproductive toxicology (Elmsford, N.Y.)
Hu Y,Wang Y,Yan T,Feng D,Ba Y,Zhang H,Zhu J,Cheng X,Cui L,Huang H
Fri Mar 01 00:00:00 EST 2019
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Journal of molecular neuroscience : MN
Yang Q,Lin J,Zhang H,Liu Y,Kan M,Xiu Z,Chen X,Lan X,Li X,Shi X,Li N,Qu X
Tue Jan 01 00:00:00 EST 2019
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Journal of molecular neuroscience : MN
Yang Q,Lin J,Zhang H,Liu Y,Kan M,Xiu Z,Chen X,Lan X,Li X,Shi X,Li N,Qu X
Tue Jan 01 00:00:00 EST 2019
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Journal of molecular neuroscience : MN
Yang Q,Lin J,Zhang H,Liu Y,Kan M,Xiu Z,Chen X,Lan X,Li X,Shi X,Li N,Qu X
Tue Jan 01 00:00:00 EST 2019
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Journal of molecular neuroscience : MN
Yang Q,Lin J,Zhang H,Liu Y,Kan M,Xiu Z,Chen X,Lan X,Li X,Shi X,Li N,Qu X
Tue Jan 01 00:00:00 EST 2019
Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos.
The Journal of reproduction and development
Ullah O,Li Z,Ali I,Xu L,Liu H,Shah SZA,Fang N
Fri Feb 08 00:00:00 EST 2019
Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos.
The Journal of reproduction and development
Ullah O,Li Z,Ali I,Xu L,Liu H,Shah SZA,Fang N
Fri Feb 08 00:00:00 EST 2019
Oxidative gastric mucosal damage induced by ischemia/reperfusion and the mechanisms of its prevention by carbon monoxide-releasing tricarbonyldichlororuthenium (II) dimer.
Free radical biology & medicine
Magierowska K,Korbut E,Hubalewska-Mazgaj M,Surmiak M,Chmura A,Bakalarz D,Buszewicz G,Wójcik D,Śliwowski Z,Ginter G,Gromowski T,Kwiecień S,Brzozowski T,Magierowski M
Sun Dec 01 00:00:00 EST 2019
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Biological & pharmaceutical bulletin
Yang P,Zhou Y,Xia Q,Yao L,Chang X
Wed May 01 00:00:00 EDT 2019
Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors.
International journal of molecular sciences
Sparaneo A,Fabrizio FP,la Torre A,Graziano P,Di Maio M,Fontana A,Bisceglia M,Rossi A,Pizzolitto S,De Maglio G,Tancredi A,Grimaldi F,Balsamo T,Centra F,Manzorra MC,Trombetta D,Pantalone A,Bonfitto A,Maiello E,Fazio VM,Muscarella LA
Thu May 23 00:00:00 EDT 2019
Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors.
International journal of molecular sciences
Sparaneo A,Fabrizio FP,la Torre A,Graziano P,Di Maio M,Fontana A,Bisceglia M,Rossi A,Pizzolitto S,De Maglio G,Tancredi A,Grimaldi F,Balsamo T,Centra F,Manzorra MC,Trombetta D,Pantalone A,Bonfitto A,Maiello E,Fazio VM,Muscarella LA
Thu May 23 00:00:00 EDT 2019
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
BioMed research international
Zhao K,Li Y,Wang Z,Han N,Wang Y
Thu Dec 12 00:00:00 EST 2019
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
BioMed research international
Zhao K,Li Y,Wang Z,Han N,Wang Y
Thu Dec 12 00:00:00 EST 2019
Torularhodin Ameliorates Oxidative Activity in Vitro and d-Galactose-Induced Liver Injury via the Nrf2/HO-1 Signaling Pathway in Vivo.
Journal of agricultural and food chemistry
Liu C,Cui Y,Pi F,Guo Y,Cheng Y,Qian H
Wed Sep 11 00:00:00 EDT 2019
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Free radical biology & medicine
Qin M,Long F,Wu W,Yang D,Huang M,Xiao C,Chen X,Liu X,Zhu YZ
Sat Jun 01 00:00:00 EDT 2019
p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yamada M,Iwata M,Warabi E,Oishi H,Lira VA,Okutsu M
Mon Jul 01 00:00:00 EDT 2019
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Oxidative medicine and cellular longevity
Yan X,Fu X,Jia Y,Ma X,Tao J,Yang T,Ma H,Liang X,Liu X,Yang J,Wei J
Fri Dec 13 00:00:00 EST 2019
Polysaccharide from Okra (Abelmoschus esculentus (L.) Moench) Improves Antioxidant Capacity via PI3K/AKT Pathways and Nrf2 Translocation in a Type 2 Diabetes Model.
Molecules (Basel, Switzerland)
Liao Z,Zhang J,Liu B,Yan T,Xu F,Xiao F,Wu B,Bi K,Jia Y
Fri May 17 00:00:00 EDT 2019
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Cells
Xu B,Lang LM,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Tue Jun 18 00:00:00 EDT 2019
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Cells
Xu B,Lang LM,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Tue Jun 18 00:00:00 EDT 2019
Astragaloside IV Protects Against Oxidative Stress in Calf Small Intestine Epithelial Cells via NFE2L2-Antioxidant Response Element Signaling.
International journal of molecular sciences
Wang Y,Jiang F,Cheng H,Tan X,Liu Y,Wei C,Song E
Thu Dec 05 00:00:00 EST 2019
Astragaloside IV Protects Against Oxidative Stress in Calf Small Intestine Epithelial Cells via NFE2L2-Antioxidant Response Element Signaling.
International journal of molecular sciences
Wang Y,Jiang F,Cheng H,Tan X,Liu Y,Wei C,Song E
Thu Dec 05 00:00:00 EST 2019
(-)-Epicatechin mitigates radiation-induced intestinal injury and promotes intestinal regeneration via suppressing oxidative stress.
Free radical research
Li Y,Ma S,Zhang Y,Yao M,Zhu X,Guan F
Thu Aug 01 00:00:00 EDT 2019
Hydrogen sulfide ameliorates disorders in the parafacial respiratory group region of neonatal rats caused by prenatal cigarette smoke exposure via an antioxidative effect.
Environmental toxicology and pharmacology
Yan X,Zhao F,Zhang S,Lei F,Wang W,Zheng Y
Wed May 01 00:00:00 EDT 2019
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Gao X,Jiang S,Du Z,Ke A,Liang Q,Li X
Mon May 04 00:00:00 EDT 2020
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Gao X,Jiang S,Du Z,Ke A,Liang Q,Li X
Mon May 04 00:00:00 EDT 2020
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Aging
Sun K,Luo J,Jing X,Guo J,Yao X,Hao X,Ye Y,Liang S,Lin J,Wang G,Guo F
Tue Nov 26 00:00:00 EST 2019
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Free radical biology & medicine
Li AL,Shen T,Wang T,Zhou MX,Wang B,Song JT,Zhang PL,Wang XL,Ren DM,Lou HX,Wang XN
Sun Sep 01 00:00:00 EDT 2019
Selenepezil, a Selenium-Containing Compound, Exerts Neuroprotective Effect via Modulation of the Keap1-Nrf2-ARE Pathway and Attenuates Aβ-Induced Cognitive Impairment in Vivo.
ACS chemical neuroscience
Yan J,Pang Y,Zhuang J,Lin H,Zhang Q,Han L,Ke P,Zhuang J,Huang X
Wed Jun 19 00:00:00 EDT 2019
KLF15 regulates endobiotic and xenobiotic metabolism.
Nature metabolism
Han S,Ray JW,Pathak P,Sweet DR,Zhang R,Gao H,Jain N,Koritzinsky EH,Matoba K,Xu W,Chan ER,Simon DI,Jain MK
Mon Apr 01 00:00:00 EDT 2019
KLF15 regulates endobiotic and xenobiotic metabolism.
Nature metabolism
Han S,Ray JW,Pathak P,Sweet DR,Zhang R,Gao H,Jain N,Koritzinsky EH,Matoba K,Xu W,Chan ER,Simon DI,Jain MK
Mon Apr 01 00:00:00 EDT 2019
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Neurochemical research
Betharia S,Rondόn-Ortiz AN,Brown DA
Thu Aug 01 00:00:00 EDT 2019
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Neurochemical research
Betharia S,Rondόn-Ortiz AN,Brown DA
Thu Aug 01 00:00:00 EDT 2019
HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress.
Aging
Wang Y,Yang C,Elsheikh NAH,Li C,Yang F,Wang G,Li L
Mon Aug 12 00:00:00 EDT 2019
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 EDT 2019
An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signalling pathway and prevents oxidative insults in human lung epithelial cells.
Free radical research
Yang WJ,He JX,Zhou MX,Huang M,Wang SQ,Wang XN,Lou HX,Ren DM,Shen T
Fri Mar 01 00:00:00 EST 2019
An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signalling pathway and prevents oxidative insults in human lung epithelial cells.
Free radical research
Yang WJ,He JX,Zhou MX,Huang M,Wang SQ,Wang XN,Lou HX,Ren DM,Shen T
Fri Mar 01 00:00:00 EST 2019
An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signalling pathway and prevents oxidative insults in human lung epithelial cells.
Free radical research
Yang WJ,He JX,Zhou MX,Huang M,Wang SQ,Wang XN,Lou HX,Ren DM,Shen T
Fri Mar 01 00:00:00 EST 2019
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Oxidative medicine and cellular longevity
Zhang HF,Wang JH,Wang YL,Gao C,Gu YT,Huang J,Wang JH,Zhang Z
Thu Aug 08 00:00:00 EDT 2019
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Journal of neuroinflammation
Zhang B,Wang G,He J,Yang Q,Li D,Li J,Zhang F
Mon Apr 22 00:00:00 EDT 2019
MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway.
Atherosclerosis
Zhang J,Cai W,Fan Z,Yang C,Wang W,Xiong M,Ma C,Yang J
Fri Nov 01 00:00:00 EDT 2019
Spinosin and 6'''‑Feruloylspinosin protect the heart against acute myocardial ischemia and reperfusion in rats.
Molecular medicine reports
Gu M,He P,Lyu C,Liu X,Xu Y,Cheng S,Gu Y,Jia Y
Fri Nov 01 00:00:00 EDT 2019
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
International journal of molecular sciences
Shah SZA,Zhao D,Taglialatela G,Hussain T,Dong H,Sabir N,Mangi MH,Wu W,Lai M,Zhang X,Duan Y,Wang L,Zhou X,Yang L
Wed Mar 06 00:00:00 EST 2019
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
International journal of molecular sciences
Shah SZA,Zhao D,Taglialatela G,Hussain T,Dong H,Sabir N,Mangi MH,Wu W,Lai M,Zhang X,Duan Y,Wang L,Zhou X,Yang L
Wed Mar 06 00:00:00 EST 2019
Ellagic acid supports neuron by regulating astroglia Nrf2.
Biotechnology and applied biochemistry
Wang GQ,He XM,Zhu GF,Li DD,Shi JS,Zhang F
Sun Sep 01 00:00:00 EDT 2019
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Molecules (Basel, Switzerland)
Jing L,Jiang JR,Liu DM,Sheng JW,Zhang WF,Li ZJ,Wei LY
Mon Sep 16 00:00:00 EDT 2019
Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents.
European journal of medicinal chemistry
Wei B,Zhou J,Xu JJ,Cui J,Ping FF,Ling JJ,Chen YJ
Sun Dec 15 00:00:00 EST 2019
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Biomedical and environmental sciences : BES
Chen ZJ,Chen JX,Wu LK,Li BY,Tian YF,Xian M,Huang ZP,Yu RA
Tue Jan 01 00:00:00 EST 2019
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Neurotoxicology
Zhang C,Zhan J,Zhao M,Dai H,Deng Y,Zhou W,Zhao L
Sun Sep 01 00:00:00 EDT 2019
Xanthohumol inhibits PRRSV proliferation and alleviates oxidative stress induced by PRRSV via the Nrf2-HMOX1 axis.
Veterinary research
Liu X,Song Z,Bai J,Nauwynck H,Zhao Y,Jiang P
Wed Sep 11 00:00:00 EDT 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
Botrysphin D attenuates arsenic-induced oxidative stress in human lung epithelial cells via activating Nrf2/ARE signaling pathways.
Biochemical and biophysical research communications
Wang T,Sun XY,Li AL,Zhou MX,Han Y,Zhang JZ,Ren DM,Lou HX,Wang XN,Shen T
Sun Oct 20 00:00:00 EDT 2019
Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary.
Reproductive biology and endocrinology : RB&E
Akino N,Wada-Hiraike O,Isono W,Terao H,Honjo H,Miyamoto Y,Tanikawa M,Sone K,Hirano M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Fujii T,Osuga Y
Wed Feb 13 00:00:00 EST 2019
Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary.
Reproductive biology and endocrinology : RB&E
Akino N,Wada-Hiraike O,Isono W,Terao H,Honjo H,Miyamoto Y,Tanikawa M,Sone K,Hirano M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Fujii T,Osuga Y
Wed Feb 13 00:00:00 EST 2019
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
Marine drugs
Lin F,Yang D,Huang Y,Zhao Y,Ye J,Xiao M
Fri Sep 20 00:00:00 EDT 2019
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Aging
Wang Y,Zuo R,Wang Z,Luo L,Wu J,Zhang C,Liu M,Shi C,Zhou Y
Mon Sep 23 00:00:00 EDT 2019
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Aging
Wang Y,Zuo R,Wang Z,Luo L,Wu J,Zhang C,Liu M,Shi C,Zhou Y
Mon Sep 23 00:00:00 EDT 2019
Dietary Curcumin Supplementation Increases Antioxidant Capacity, Upregulates Nrf2 and Hmox1 Levels in the Liver of Piglet Model with Intrauterine Growth Retardation.
Nutrients
Niu Y,He J,Ahmad H,Shen M,Zhao Y,Gan Z,Zhang L,Zhong X,Wang C,Wang T
Thu Dec 05 00:00:00 EST 2019
Involvement of the PI3K/Akt/Nrf2 Signaling Pathway in Resveratrol-Mediated Reversal of Drug Resistance in HL-60/ADR Cells.
Nutrition and cancer
Li Y,Guo Y,Feng Z,Bergan R,Li B,Qin Y,Zhao L,Zhang Z,Shi M
Mon Jun 01 00:00:00 EDT 2020
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Frontiers in pharmacology
Song S,Chu L,Liang H,Chen J,Liang J,Huang Z,Zhang B,Chen X
Thu Oct 01 00:00:00 EDT 2020
Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditions.
Biochemical and biophysical research communications
Ren L,Zhan P,Wang Q,Wang C,Liu Y,Yu Z,Zhang S
Sun Jun 30 00:00:00 EDT 2019
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
BMC complementary and alternative medicine
Sun S,Du Y,Yin C,Suo X,Wang R,Xia R,Zhang X
Mon Dec 02 00:00:00 EST 2019
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Toxicology letters
Yao B,He J,Yin X,Shi Y,Wan J,Tian Z
Fri Nov 01 00:00:00 EDT 2019
The anti-nephritic activity of a polysaccharide from okra (Abelmoschus esculentus (L.) Moench) via modulation of AMPK-Sirt1-PGC-1α signaling axis mediated anti-oxidative in type 2 diabetes model mice.
International journal of biological macromolecules
Liao Z,Zhang J,Wang J,Yan T,Xu F,Wu B,Xiao F,Bi K,Niu J,Jia Y
Fri Nov 01 00:00:00 EDT 2019
S-1-propenylmercaptocysteine protects murine hepatocytes against oxidative stress via persulfidation of Keap1 and activation of Nrf2.
Free radical biology & medicine
Tocmo R,Parkin K
Fri Nov 01 00:00:00 EDT 2019
Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation.
Life sciences
Liu L,Chen H,Jin J,Tang Z,Yin P,Zhong D,Li G
Sun Dec 15 00:00:00 EST 2019
Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway.
Life sciences
Lan H,Su Y,Liu Y,Deng C,Wang J,Chen T,Jules KED,Masau JF,Li H,Wei X
Mon Jul 01 00:00:00 EDT 2019
Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.
American journal of cancer research
Liu Y,Zhang J,Liu H,Guan G,Zhang T,Wang L,Qi X,Zheng H,Chen CC,Liu J,Cao D,Lu F,Chen X
Wed Sep 30 00:00:00 EDT 2020
Protective effect of dihydroartemisinin in inhibiting senescence of myeloid-derived suppressor cells from lupus mice via Nrf2/HO-1 pathway.
Free radical biology & medicine
Li D,Qi J,Wang J,Pan Y,Li J,Xia X,Dou H,Hou Y
Fri Nov 01 00:00:00 EDT 2019
Absence of Dipeptidyl Peptidase 3 Increases Oxidative Stress and Causes Bone Loss.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Menale C,Robinson LJ,Palagano E,Rigoni R,Erreni M,Almarza AJ,Strina D,Mantero S,Lizier M,Forlino A,Besio R,Monari M,Vezzoni P,Cassani B,Blair HC,Villa A,Sobacchi C
Fri Nov 01 00:00:00 EDT 2019
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Yang Y,Chen S,Tao L,Gan S,Luo H,Xu Y,Shen X
Sat Jul 20 00:00:00 EDT 2019
Potent 5-Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1-UBE2M Interaction.
Journal of medicinal chemistry
Zhou W,Ma L,Ding L,Guo Q,He Z,Yang J,Qiao H,Li L,Yang J,Yu S,Zhao L,Wang S,Liu HM,Suo Z,Zhao W
Thu Jun 13 00:00:00 EDT 2019
Dietary Dihydroartemisinin Supplementation Attenuates Hepatic Oxidative Damage of Weaned Piglets with Intrauterine Growth Retardation through the Nrf2/ARE Signaling Pathway.
Animals : an open access journal from MDPI
Zhao Y,Niu Y,He J,Zhang L,Wang C,Wang T
Fri Dec 13 00:00:00 EST 2019
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Marine drugs
Tao W,Sun W,Liu L,Wang G,Xiao Z,Pei X,Wang M
Sat Nov 16 00:00:00 EST 2019
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
Cell metabolism
Zhu J,Berisa M,Schwörer S,Qin W,Cross JR,Thompson CB
Tue Nov 05 00:00:00 EST 2019
Costunolide inhibits pulmonary fibrosis via regulating NF-kB and TGF-β1/Smad2/Nrf2-NOX4 signaling pathways.
Biochemical and biophysical research communications
Liu B,Rong Y,Sun D,Li W,Chen H,Cao B,Wang T
Tue Mar 05 00:00:00 EST 2019
Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure.
Brain sciences
Xu B,Lang LM,Lian S,Guo JR,Wang JF,Yang HM,Li SZ
Sat Oct 12 00:00:00 EDT 2019
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Pharmacological research
Zhao X,Jin Y,Li L,Xu L,Tang Z,Qi Y,Yin L,Peng J
Thu Aug 01 00:00:00 EDT 2019
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Neurochemical research
Xu Y,Tang D,Wang J,Wei H,Gao J
Fri Nov 01 00:00:00 EDT 2019
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Neural regeneration research
Xie YK,Zhou X,Yuan HT,Qiu J,Xin DQ,Chu XL,Wang DC,Wang Z
Tue Oct 01 00:00:00 EDT 2019
Effects of Ethyl Pyruvate on Bile Duct Ligation-Induced Liver Fibrosis by Regulating Nrf2 Pathway and Proinflammatory Cytokines in Rats.
Gastroenterology research and practice
Zong Y,Zhang M,Li S,Qi W,Li J,Liu T,Yang H,Lu C,Hu X
Tue Apr 12 00:00:00 EDT 2022
CCl4-Induced Liver Injury Was Ameliorated by Qi-Ge Decoction through the Antioxidant Pathway.
Evidence-based complementary and alternative medicine : eCAM
Peng C,Zhou ZM,Li J,Luo Y,Zhou YS,Ke XH,Huang KE
Wed Sep 30 00:00:00 EDT 2020
CCl4-Induced Liver Injury Was Ameliorated by Qi-Ge Decoction through the Antioxidant Pathway.
Evidence-based complementary and alternative medicine : eCAM
Peng C,Zhou ZM,Li J,Luo Y,Zhou YS,Ke XH,Huang KE
Wed Sep 30 00:00:00 EDT 2020
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Thu Aug 01 00:00:00 EDT 2019
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
International immunopharmacology
Zheng Y,Zhu G,He J,Wang G,Li D,Zhang F
Thu Aug 01 00:00:00 EDT 2019
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
International immunopharmacology
Zheng Y,Zhu G,He J,Wang G,Li D,Zhang F
Thu Aug 01 00:00:00 EDT 2019
Synthesis and biological activities of petrosiols B and D.
RSC advances
Geng J,Ren Q,Chang C,Xie X,Liu J,Du Y
Thu Mar 28 00:00:00 EDT 2019
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Food & function
Shu G,Qiu Y,Hao J,Fu Q,Deng X
Wed Oct 16 00:00:00 EDT 2019
SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway.
Frontiers in oncology
Sun X,Wang S,Gai J,Guan J,Li J,Li Y,Zhao J,Zhao C,Fu L,Li Q
Tue Sep 29 00:00:00 EDT 2020
Lysosomal dysfunction is associated with persistent lung injury in dams caused by pregnancy exposure to carbon black nanoparticles.
Life sciences
Liu X,Tu B,Jiang X,Xu G,Bai L,Zhang L,Meng P,Qin X,Chen C,Zou Z
Sun Sep 15 00:00:00 EDT 2019
Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway.
Oxidative medicine and cellular longevity
Liao HH,Zhang N,Meng YY,Feng H,Yang JJ,Li WJ,Chen S,Wu HM,Deng W,Tang QZ
Thu Jun 25 00:00:00 EDT 2020
Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer.
Redox biology
Wang M,Xue Y,Shen L,Qin P,Sang X,Tao Z,Yi J,Wang J,Liu P,Cheng H
Sat Jun 01 00:00:00 EDT 2019
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1.
Aging
Cheng FY,Lee YH,Hsu YH,Chiu IJ,Chiu YJ,Lin YF,Chiu HW
Tue Nov 12 00:00:00 EST 2019
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1.
Aging
Cheng FY,Lee YH,Hsu YH,Chiu IJ,Chiu YJ,Lin YF,Chiu HW
Tue Nov 12 00:00:00 EST 2019
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Journal of bioenergetics and biomembranes
Li L,Liu T,Liu L,Li S,Zhang Z,Zhang R,Zhou Y,Liu F
Sun Dec 01 00:00:00 EST 2019
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Journal of bioenergetics and biomembranes
Li L,Liu T,Liu L,Li S,Zhang Z,Zhang R,Zhou Y,Liu F
Sun Dec 01 00:00:00 EST 2019
Betaine protects against heat exposure-induced oxidative stress and apoptosis in bovine mammary epithelial cells via regulation of ROS production.
Cell stress & chaperones
Li C,Wang Y,Li L,Han Z,Mao S,Wang G
Fri Mar 01 00:00:00 EST 2019
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Journal of ethnopharmacology
Lu Q,Tan S,Gu W,Li F,Hua W,Zhang S,Chen F,Tang L
Mon Oct 28 00:00:00 EDT 2019
Protective Effects of Fucoidan against Hydrogen Peroxide-Induced Oxidative Damage in Porcine Intestinal Epithelial Cells.
Animals : an open access journal from MDPI
Li Y,Zhao W,Wang L,Chen Y,Zhang H,Wang T,Yang X,Xing F,Yan J,Fang X
Tue Dec 10 00:00:00 EST 2019
CGRP Reduces Apoptosis of DRG Cells Induced by High-Glucose Oxidative Stress Injury through PI3K/AKT Induction of Heme Oxygenase-1 and Nrf-2 Expression.
Oxidative medicine and cellular longevity
Liu Y,Zhang S,Xue J,Wei Z,Ao P,Shen B,Ding L
Fri May 01 00:00:00 EDT 2020
Neuroprotective Effect of Dioscin on the Aging Brain.
Molecules (Basel, Switzerland)
Qi Y,Li R,Xu L,Yin L,Xu Y,Han X,Peng J
Sat Mar 30 00:00:00 EDT 2019
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Journal of the science of food and agriculture
Wang Z,Liang M,Li H,Cai L,He H,Wu Q,Yang L
Thu Aug 15 00:00:00 EDT 2019
The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM2.5).
Chemosphere
Dai P,Shen D,Shen J,Tang Q,Xi M,Li Y,Li C
Fri Nov 01 00:00:00 EDT 2019
Curcumin Alleviates IUGR Jejunum Damage by Increasing Antioxidant Capacity through Nrf2/Keap1 Pathway in Growing Pigs.
Animals : an open access journal from MDPI
Yan E,Zhang J,Han H,Wu J,Gan Z,Wei C,Zhang L,Wang C,Wang T
Tue Dec 24 00:00:00 EST 2019
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Journal of medicinal food
Luo J,Long Y,Ren G,Zhang Y,Chen J,Huang R,Yang L
Sun Dec 01 00:00:00 EST 2019
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Chemico-biological interactions
Wu XY,Chen XM,Zhou MX,Hu HX,Zhang JZ,Wang XN,Ren DM,Lou HX,Shen T
Sun Sep 01 00:00:00 EDT 2019
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
Metabolic brain disease
Gao W,Wang W,Zhang J,Deng P,Hu J,Yang J,Deng Z
Tue Oct 01 00:00:00 EDT 2019
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
Metabolic brain disease
Gao W,Wang W,Zhang J,Deng P,Hu J,Yang J,Deng Z
Tue Oct 01 00:00:00 EDT 2019
Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats.
Journal of the science of food and agriculture
Liang M,Li H,Wang Z,Cai L,Yang L
Tue Oct 01 00:00:00 EDT 2019
Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditis.
Free radical biology & medicine
Meng N,Tang H,Zhang H,Jiang C,Su L,Min X,Zhang W,Zhang H,Miao Z,Zhang W,Zhuang C
Thu Mar 01 00:00:00 EST 2018
Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditis.
Free radical biology & medicine
Meng N,Tang H,Zhang H,Jiang C,Su L,Min X,Zhang W,Zhang H,Miao Z,Zhang W,Zhuang C
Thu Mar 01 00:00:00 EST 2018
Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditis.
Free radical biology & medicine
Meng N,Tang H,Zhang H,Jiang C,Su L,Min X,Zhang W,Zhang H,Miao Z,Zhang W,Zhuang C
Thu Mar 01 00:00:00 EST 2018
Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditis.
Free radical biology & medicine
Meng N,Tang H,Zhang H,Jiang C,Su L,Min X,Zhang W,Zhang H,Miao Z,Zhang W,Zhuang C
Thu Mar 01 00:00:00 EST 2018
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.
Free radical biology & medicine
Li H,Tang Z,Chu P,Song Y,Yang Y,Sun B,Niu M,Qaed E,Shopit A,Han G,Ma X,Peng J,Hu M,Tang Z
Sun May 20 00:00:00 EDT 2018
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.
Free radical biology & medicine
Li H,Tang Z,Chu P,Song Y,Yang Y,Sun B,Niu M,Qaed E,Shopit A,Han G,Ma X,Peng J,Hu M,Tang Z
Sun May 20 00:00:00 EDT 2018
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.
Free radical biology & medicine
Li H,Tang Z,Chu P,Song Y,Yang Y,Sun B,Niu M,Qaed E,Shopit A,Han G,Ma X,Peng J,Hu M,Tang Z
Sun May 20 00:00:00 EDT 2018
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 EST 2018
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 EST 2018
Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gao W,Xiao C,Hu J,Chen B,Wang C,Cui B,Deng P,Yang J,Deng Z
Sun Jul 01 00:00:00 EDT 2018
Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gao W,Xiao C,Hu J,Chen B,Wang C,Cui B,Deng P,Yang J,Deng Z
Sun Jul 01 00:00:00 EDT 2018
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Oxidative medicine and cellular longevity
Li YR,Li GH,Sun L,Li L,Liu Y,Kong DG,Wang SQ,Ren DM,Wang XN,Lou HX,Shen T
Mon Oct 22 00:00:00 EDT 2018
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Oxidative medicine and cellular longevity
Li YR,Li GH,Sun L,Li L,Liu Y,Kong DG,Wang SQ,Ren DM,Wang XN,Lou HX,Shen T
Mon Oct 22 00:00:00 EDT 2018
Exposure to formaldehyde and diisononyl phthalate exacerbate neuroinflammation through NF-κB activation in a mouse asthma model.
Ecotoxicology and environmental safety
Duan J,Kang J,Qin W,Deng T,Liu H,Li B,Yu W,Gong S,Yang X,Chen M
Thu Nov 15 00:00:00 EST 2018
Exposure to formaldehyde and diisononyl phthalate exacerbate neuroinflammation through NF-κB activation in a mouse asthma model.
Ecotoxicology and environmental safety
Duan J,Kang J,Qin W,Deng T,Liu H,Li B,Yu W,Gong S,Yang X,Chen M
Thu Nov 15 00:00:00 EST 2018
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Phytotherapy research : PTR
Li Y,Fu S,Li E,Sun X,Xu H,Meng Y,Wang X,Chen Y,Xie C,Geng S,Wu J,Zhong C,Xu P
Sat Dec 01 00:00:00 EST 2018
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Phytotherapy research : PTR
Li Y,Fu S,Li E,Sun X,Xu H,Meng Y,Wang X,Chen Y,Xie C,Geng S,Wu J,Zhong C,Xu P
Sat Dec 01 00:00:00 EST 2018
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Food & function
Zhai X,Lin D,Zhao Y,Li W,Yang X
Wed Oct 17 00:00:00 EDT 2018
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Food & function
Zhai X,Lin D,Zhao Y,Li W,Yang X
Wed Oct 17 00:00:00 EDT 2018
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Biochemical pharmacology
Wang Z,Yuan S,Li Y,Zhang Z,Xiao W,Tang D,Ye K,Liu Z,Wang C,Zheng Y,Nie H,Chen H
Sun Apr 01 00:00:00 EDT 2018
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Biochemical pharmacology
Wang Z,Yuan S,Li Y,Zhang Z,Xiao W,Tang D,Ye K,Liu Z,Wang C,Zheng Y,Nie H,Chen H
Sun Apr 01 00:00:00 EDT 2018
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.
International journal of oncology
Zhang TT,Qu N,Sun GH,Zhang L,Wang YJ,Mu XM,Wei WJ,Wang YL,Wang Y,Ji QH,Zhu YX,Shi RL
Wed Aug 01 00:00:00 EDT 2018
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.
International journal of oncology
Zhang TT,Qu N,Sun GH,Zhang L,Wang YJ,Mu XM,Wei WJ,Wang YL,Wang Y,Ji QH,Zhu YX,Shi RL
Wed Aug 01 00:00:00 EDT 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 EST 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 EST 2018
A novel Gallic acid derivative attenuates BLM-induced pulmonary fibrosis in mice.
International immunopharmacology
Rong Y,Cao B,Liu B,Li W,Chen Y,Chen H,Liu Y,Liu T
Thu Nov 01 00:00:00 EDT 2018
A novel Gallic acid derivative attenuates BLM-induced pulmonary fibrosis in mice.
International immunopharmacology
Rong Y,Cao B,Liu B,Li W,Chen Y,Chen H,Liu Y,Liu T
Thu Nov 01 00:00:00 EDT 2018
A novel Gallic acid derivative attenuates BLM-induced pulmonary fibrosis in mice.
International immunopharmacology
Rong Y,Cao B,Liu B,Li W,Chen Y,Chen H,Liu Y,Liu T
Thu Nov 01 00:00:00 EDT 2018
A novel Gallic acid derivative attenuates BLM-induced pulmonary fibrosis in mice.
International immunopharmacology
Rong Y,Cao B,Liu B,Li W,Chen Y,Chen H,Liu Y,Liu T
Thu Nov 01 00:00:00 EDT 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 EST 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 EST 2018
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Molecular neurobiology
Dai C,Ciccotosto GD,Cappai R,Tang S,Li D,Xie S,Xiao X,Velkov T
Mon Jan 01 00:00:00 EST 2018
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Molecular neurobiology
Dai C,Ciccotosto GD,Cappai R,Tang S,Li D,Xie S,Xiao X,Velkov T
Mon Jan 01 00:00:00 EST 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 EDT 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 EDT 2018
T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhang X,Wang Y,Velkov T,Tang S,Dai C
Sun Apr 01 00:00:00 EDT 2018
T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhang X,Wang Y,Velkov T,Tang S,Dai C
Sun Apr 01 00:00:00 EDT 2018
T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhang X,Wang Y,Velkov T,Tang S,Dai C
Sun Apr 01 00:00:00 EDT 2018
T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhang X,Wang Y,Velkov T,Tang S,Dai C
Sun Apr 01 00:00:00 EDT 2018
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice.
Journal of ethnopharmacology
Yang WJ,Li YR,Gao H,Wu XY,Wang XL,Wang XN,Xiang L,Ren DM,Lou HX,Shen T
Wed Dec 05 00:00:00 EST 2018
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice.
Journal of ethnopharmacology
Yang WJ,Li YR,Gao H,Wu XY,Wang XL,Wang XN,Xiang L,Ren DM,Lou HX,Shen T
Wed Dec 05 00:00:00 EST 2018
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice.
Journal of ethnopharmacology
Yang WJ,Li YR,Gao H,Wu XY,Wang XL,Wang XN,Xiang L,Ren DM,Lou HX,Shen T
Wed Dec 05 00:00:00 EST 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
Activation of Nrf2 might reduce oxidative stress in human granulosa cells.
Molecular and cellular endocrinology
Akino N,Wada-Hiraike O,Terao H,Honjoh H,Isono W,Fu H,Hirano M,Miyamoto Y,Tanikawa M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Kawana K,Fujii T,Osuga Y
Sun Jul 15 00:00:00 EDT 2018
Activation of Nrf2 might reduce oxidative stress in human granulosa cells.
Molecular and cellular endocrinology
Akino N,Wada-Hiraike O,Terao H,Honjoh H,Isono W,Fu H,Hirano M,Miyamoto Y,Tanikawa M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Kawana K,Fujii T,Osuga Y
Sun Jul 15 00:00:00 EDT 2018
Activation of Nrf2 might reduce oxidative stress in human granulosa cells.
Molecular and cellular endocrinology
Akino N,Wada-Hiraike O,Terao H,Honjoh H,Isono W,Fu H,Hirano M,Miyamoto Y,Tanikawa M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Kawana K,Fujii T,Osuga Y
Sun Jul 15 00:00:00 EDT 2018
Activation of Nrf2 might reduce oxidative stress in human granulosa cells.
Molecular and cellular endocrinology
Akino N,Wada-Hiraike O,Terao H,Honjoh H,Isono W,Fu H,Hirano M,Miyamoto Y,Tanikawa M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Kawana K,Fujii T,Osuga Y
Sun Jul 15 00:00:00 EDT 2018
Activation of Nrf2 might reduce oxidative stress in human granulosa cells.
Molecular and cellular endocrinology
Akino N,Wada-Hiraike O,Terao H,Honjoh H,Isono W,Fu H,Hirano M,Miyamoto Y,Tanikawa M,Harada M,Hirata T,Hirota Y,Koga K,Oda K,Kawana K,Fujii T,Osuga Y
Sun Jul 15 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Toxicology letters
Qiao Y,Xu L,Tao X,Yin L,Qi Y,Xu Y,Han X,Tang Z,Ma X,Liu K,Peng J
Thu Mar 01 00:00:00 EST 2018
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Toxicology letters
Qiao Y,Xu L,Tao X,Yin L,Qi Y,Xu Y,Han X,Tang Z,Ma X,Liu K,Peng J
Thu Mar 01 00:00:00 EST 2018
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
Environmental toxicology
Lin EY,Bayarsengee U,Wang CC,Chiang YH,Cheng CW
Mon Jan 01 00:00:00 EST 2018
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
Environmental toxicology
Lin EY,Bayarsengee U,Wang CC,Chiang YH,Cheng CW
Mon Jan 01 00:00:00 EST 2018
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
Environmental toxicology
Lin EY,Bayarsengee U,Wang CC,Chiang YH,Cheng CW
Mon Jan 01 00:00:00 EST 2018
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
Environmental toxicology
Lin EY,Bayarsengee U,Wang CC,Chiang YH,Cheng CW
Mon Jan 01 00:00:00 EST 2018
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks.
Biological trace element research
Khaliq H,Jing W,Ke X,Ke-Li Y,Peng-Peng S,Cui L,Wei-Wei Q,Zhixin L,Hua-Zhen L,Hui S,Ju-Ming Z,Ke-Mei P
Thu Nov 01 00:00:00 EDT 2018
Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks.
Biological trace element research
Khaliq H,Jing W,Ke X,Ke-Li Y,Peng-Peng S,Cui L,Wei-Wei Q,Zhixin L,Hua-Zhen L,Hui S,Ju-Ming Z,Ke-Mei P
Thu Nov 01 00:00:00 EDT 2018
Anti-neovascularization effects of DMBT in age-related macular degeneration by inhibition of VEGF secretion through ROS-dependent signaling pathway.
Molecular and cellular biochemistry
Chen S,Zhou Y,Zhou L,Guan Y,Zhang Y,Han X
Thu Nov 01 00:00:00 EDT 2018
Anti-neovascularization effects of DMBT in age-related macular degeneration by inhibition of VEGF secretion through ROS-dependent signaling pathway.
Molecular and cellular biochemistry
Chen S,Zhou Y,Zhou L,Guan Y,Zhang Y,Han X
Thu Nov 01 00:00:00 EDT 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 EDT 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2‑ARE signaling pathway.
Molecular medicine reports
Xue S,He W,Zeng X,Tang Z,Feng S,Zhong Z,Xiong Y,Wang Y,Ye Q
Sun Jul 01 00:00:00 EDT 2018
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2‑ARE signaling pathway.
Molecular medicine reports
Xue S,He W,Zeng X,Tang Z,Feng S,Zhong Z,Xiong Y,Wang Y,Ye Q
Sun Jul 01 00:00:00 EDT 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Biochemical and biophysical research communications
Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y
Mon Jan 01 00:00:00 EST 2018
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Biochemical and biophysical research communications
Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y
Mon Jan 01 00:00:00 EST 2018
Hepatoprotective Activity of the Ethanolic Extract of Polygonum multiflorum Thunb. against Oxidative Stress-Induced Liver Injury.
Evidence-based complementary and alternative medicine : eCAM
Lin EY,Chagnaadorj A,Huang SJ,Wang CC,Chiang YH,Cheng CW
Wed Sep 30 00:00:00 EDT 2020
Hepatoprotective Activity of the Ethanolic Extract of Polygonum multiflorum Thunb. against Oxidative Stress-Induced Liver Injury.
Evidence-based complementary and alternative medicine : eCAM
Lin EY,Chagnaadorj A,Huang SJ,Wang CC,Chiang YH,Cheng CW
Wed Sep 30 00:00:00 EDT 2020
Hepatoprotective Activity of the Ethanolic Extract of Polygonum multiflorum Thunb. against Oxidative Stress-Induced Liver Injury.
Evidence-based complementary and alternative medicine : eCAM
Lin EY,Chagnaadorj A,Huang SJ,Wang CC,Chiang YH,Cheng CW
Wed Sep 30 00:00:00 EDT 2020
Hepatoprotective Activity of the Ethanolic Extract of Polygonum multiflorum Thunb. against Oxidative Stress-Induced Liver Injury.
Evidence-based complementary and alternative medicine : eCAM
Lin EY,Chagnaadorj A,Huang SJ,Wang CC,Chiang YH,Cheng CW
Wed Sep 30 00:00:00 EDT 2020
Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis.
Experimental animals
Akiyama K,Warabi E,Okada K,Yanagawa T,Ishii T,Kose K,Tokushige K,Ishige K,Mizokami Y,Yamagata K,Onizawa K,Ariizumi SI,Yamamoto M,Shoda J
Thu May 10 00:00:00 EDT 2018
Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis.
Experimental animals
Akiyama K,Warabi E,Okada K,Yanagawa T,Ishii T,Kose K,Tokushige K,Ishige K,Mizokami Y,Yamagata K,Onizawa K,Ariizumi SI,Yamamoto M,Shoda J
Thu May 10 00:00:00 EDT 2018
Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea.
Respiratory research
Li L,Ren F,Qi C,Xu L,Fang Y,Liang M,Feng J,Chen B,Ning W,Cao J
Mon Feb 12 00:00:00 EST 2018
Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea.
Respiratory research
Li L,Ren F,Qi C,Xu L,Fang Y,Liang M,Feng J,Chen B,Ning W,Cao J
Mon Feb 12 00:00:00 EST 2018
Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases in Vitro and in Vivo: Regulation of Redox Biology and Mitochondrial Function.
Frontiers in aging neuroscience
Li X,Cui XX,Chen YJ,Wu TT,Xu H,Yin H,Wu YC
Thu Oct 01 00:00:00 EDT 2020
β-glucan Salecan Improves Exercise Performance and Displays Anti-Fatigue Effects through Regulating Energy Metabolism and Oxidative Stress in Mice.
Nutrients
Xu X,Ding Y,Yang Y,Gao Y,Sun Q,Liu J,Yang X,Wang J,Zhang J
Tue Jul 03 00:00:00 EDT 2018
β-glucan Salecan Improves Exercise Performance and Displays Anti-Fatigue Effects through Regulating Energy Metabolism and Oxidative Stress in Mice.
Nutrients
Xu X,Ding Y,Yang Y,Gao Y,Sun Q,Liu J,Yang X,Wang J,Zhang J
Tue Jul 03 00:00:00 EDT 2018
Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1.
Frontiers in pharmacology
Zhang L,Chen Z,Gong W,Zou Y,Xu F,Chen L,Huang H
Thu Oct 01 00:00:00 EDT 2020
Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1.
Frontiers in pharmacology
Zhang L,Chen Z,Gong W,Zou Y,Xu F,Chen L,Huang H
Thu Oct 01 00:00:00 EDT 2020
Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1.
Frontiers in pharmacology
Zhang L,Chen Z,Gong W,Zou Y,Xu F,Chen L,Huang H
Thu Oct 01 00:00:00 EDT 2020
Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1.
Frontiers in pharmacology
Zhang L,Chen Z,Gong W,Zou Y,Xu F,Chen L,Huang H
Thu Oct 01 00:00:00 EDT 2020
Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.
PloS one
Belcher JD,Gomperts E,Nguyen J,Chen C,Abdulla F,Kiser ZM,Gallo D,Levy H,Otterbein LE,Vercellotti GM
Wed Mar 20 00:00:00 EDT 2019
Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.
PloS one
Belcher JD,Gomperts E,Nguyen J,Chen C,Abdulla F,Kiser ZM,Gallo D,Levy H,Otterbein LE,Vercellotti GM
Wed Mar 20 00:00:00 EDT 2019
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Translational neuroscience
Daicheng H,Shiwen X,Huaping Z,Yong L,Qianqian Z,Changxia H
Thu Mar 31 00:00:00 EDT 2022
Renoprotective Effects of Antroquinonol in Rats with Nω-Nitro-l-Arginine Methyl Ester-Induced Hypertension.
Nutrients
Chen JR,Ko J,Yeh WJ,Huang WC,Yang HY
Wed Oct 17 00:00:00 EDT 2018
Renoprotective Effects of Antroquinonol in Rats with Nω-Nitro-l-Arginine Methyl Ester-Induced Hypertension.
Nutrients
Chen JR,Ko J,Yeh WJ,Huang WC,Yang HY
Wed Oct 17 00:00:00 EDT 2018
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
ACS chemical neuroscience
Dai C,Ciccotosto GD,Cappai R,Wang Y,Tang S,Hoyer D,Schneider EK,Velkov T,Xiao X
Wed Apr 18 00:00:00 EDT 2018
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
ACS chemical neuroscience
Dai C,Ciccotosto GD,Cappai R,Wang Y,Tang S,Hoyer D,Schneider EK,Velkov T,Xiao X
Wed Apr 18 00:00:00 EDT 2018
NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.
eLife
Wible RS,Ramanathan C,Sutter CH,Olesen KM,Kensler TW,Liu AC,Sutter TR
Mon Feb 26 00:00:00 EST 2018
NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.
eLife
Wible RS,Ramanathan C,Sutter CH,Olesen KM,Kensler TW,Liu AC,Sutter TR
Mon Feb 26 00:00:00 EST 2018
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Medicine and science in sports and exercise
Wu C,Yang L,Tucker D,Dong Y,Zhu L,Duan R,Liu TC,Zhang Q
Tue May 01 00:00:00 EDT 2018
Nrf2 protects stellate cells from Smad-dependent cell activation.
PloS one
Prestigiacomo V,Suter-Dick L
Mon Jan 14 00:00:00 EST 2019
Nrf2 protects stellate cells from Smad-dependent cell activation.
PloS one
Prestigiacomo V,Suter-Dick L
Mon Jan 14 00:00:00 EST 2019
Nrf2 protects stellate cells from Smad-dependent cell activation.
PloS one
Prestigiacomo V,Suter-Dick L
Mon Jan 14 00:00:00 EST 2019
Nrf2 protects stellate cells from Smad-dependent cell activation.
PloS one
Prestigiacomo V,Suter-Dick L
Mon Jan 14 00:00:00 EST 2019
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao M,Li C,Xu M,Liu Y,Cong M,Liu S
Sun Jul 01 00:00:00 EDT 2018
LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao M,Li C,Xu M,Liu Y,Cong M,Liu S
Sun Jul 01 00:00:00 EDT 2018
Local low dose curcumin treatment improves functional recovery and remyelination in a rat model of sciatic nerve crush through inhibition of oxidative stress.
Neuropharmacology
Caillaud M,Chantemargue B,Richard L,Vignaud L,Favreau F,Faye PA,Vignoles P,Sturtz F,Trouillas P,Vallat JM,Desmoulière A,Billet F
Sat Sep 01 00:00:00 EDT 2018
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge.
Journal of neuroinflammation
Paraiso HC,Kuo PC,Curfman ET,Moon HJ,Sweazey RD,Yen JH,Chang FL,Yu IC
Thu Mar 29 00:00:00 EDT 2018
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge.
Journal of neuroinflammation
Paraiso HC,Kuo PC,Curfman ET,Moon HJ,Sweazey RD,Yen JH,Chang FL,Yu IC
Thu Mar 29 00:00:00 EDT 2018
A small molecule targeting glutathione activates Nrf2 and inhibits cancer cell growth through promoting Keap-1 S-glutathionylation and inducing apoptosis.
RSC advances
Wang L,Qu G,Gao Y,Su L,Ye Q,Jiang F,Zhao B,Miao J
Tue Jan 02 00:00:00 EST 2018
A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis.
Frontiers in immunology
Ren Z,Li H,Zhang M,Zhao Y,Fang X,Li X,Chen W,Zhang H,Wang Y,Pan LL,Sun J
Thu Oct 03 00:00:00 EDT 2019
A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis.
Frontiers in immunology
Ren Z,Li H,Zhang M,Zhao Y,Fang X,Li X,Chen W,Zhang H,Wang Y,Pan LL,Sun J
Thu Oct 03 00:00:00 EDT 2019
The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer.
Oncotarget
Evans JP,Winiarski BK,Sutton PA,Jones RP,Ressel L,Duckworth CA,Pritchard DM,Lin ZX,Fretwell VL,Tweedle EM,Costello E,Goldring CE,Copple IM,Park BK,Palmer DH,Kitteringham NR
Tue Jun 05 00:00:00 EDT 2018
The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer.
Oncotarget
Evans JP,Winiarski BK,Sutton PA,Jones RP,Ressel L,Duckworth CA,Pritchard DM,Lin ZX,Fretwell VL,Tweedle EM,Costello E,Goldring CE,Copple IM,Park BK,Palmer DH,Kitteringham NR
Tue Jun 05 00:00:00 EDT 2018
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Redox biology
Li D,Wang X,Huang Q,Li S,Zhou Y,Li Z
Tue May 01 00:00:00 EDT 2018
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Redox biology
Li D,Wang X,Huang Q,Li S,Zhou Y,Li Z
Tue May 01 00:00:00 EDT 2018
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
International journal of molecular sciences
Tang X,Liu B,Wang X,Yu Q,Fang R
Wed Mar 14 00:00:00 EDT 2018
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
International journal of molecular sciences
Tang X,Liu B,Wang X,Yu Q,Fang R
Wed Mar 14 00:00:00 EDT 2018
Protective Effects of Hydrogen Sulfide Against Cigarette Smoke Exposure-Induced Placental Oxidative Damage by Alleviating Redox Imbalance via Nrf2 Pathway in Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhao F,Lei F,Yan X,Zhang S,Wang W,Zheng Y
Mon Sep 10 00:00:00 EDT 2018
Protective Effects of Hydrogen Sulfide Against Cigarette Smoke Exposure-Induced Placental Oxidative Damage by Alleviating Redox Imbalance via Nrf2 Pathway in Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhao F,Lei F,Yan X,Zhang S,Wang W,Zheng Y
Mon Sep 10 00:00:00 EDT 2018
Protective Effects of Hydrogen Sulfide Against Cigarette Smoke Exposure-Induced Placental Oxidative Damage by Alleviating Redox Imbalance via Nrf2 Pathway in Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhao F,Lei F,Yan X,Zhang S,Wang W,Zheng Y
Mon Sep 10 00:00:00 EDT 2018
Protective Effects of Hydrogen Sulfide Against Cigarette Smoke Exposure-Induced Placental Oxidative Damage by Alleviating Redox Imbalance via Nrf2 Pathway in Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhao F,Lei F,Yan X,Zhang S,Wang W,Zheng Y
Mon Sep 10 00:00:00 EDT 2018
Curcumin Attenuates on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Modulation of the Nrf2/HO-1 and TGF-β1/Smad3 Pathway.
Molecules (Basel, Switzerland)
Peng X,Dai C,Liu Q,Li J,Qiu J
Fri Jan 19 00:00:00 EST 2018
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Cancer cell
Ge W,Zhao K,Wang X,Li H,Yu M,He M,Xue X,Zhu Y,Zhang C,Cheng Y,Jiang S,Hu Y
Mon Nov 13 00:00:00 EST 2017
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Cancer cell
Ge W,Zhao K,Wang X,Li H,Yu M,He M,Xue X,Zhu Y,Zhang C,Cheng Y,Jiang S,Hu Y
Mon Nov 13 00:00:00 EST 2017
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Cancer cell
Ge W,Zhao K,Wang X,Li H,Yu M,He M,Xue X,Zhu Y,Zhang C,Cheng Y,Jiang S,Hu Y
Mon Nov 13 00:00:00 EST 2017
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding.
Cancer cell
Ge W,Zhao K,Wang X,Li H,Yu M,He M,Xue X,Zhu Y,Zhang C,Cheng Y,Jiang S,Hu Y
Mon Nov 13 00:00:00 EST 2017
3H-1,2-Dithiole-3-thione as a novel therapeutic agent for the treatment of ischemic stroke through Nrf2 defense pathway.
Brain, behavior, and immunity
Kuo PC,Yu IC,Scofield BA,Brown DA,Curfman ET,Paraiso HC,Chang FL,Yen JH
Mon May 01 00:00:00 EDT 2017
3H-1,2-Dithiole-3-thione as a novel therapeutic agent for the treatment of ischemic stroke through Nrf2 defense pathway.
Brain, behavior, and immunity
Kuo PC,Yu IC,Scofield BA,Brown DA,Curfman ET,Paraiso HC,Chang FL,Yen JH
Mon May 01 00:00:00 EDT 2017
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.
Biomaterials
Gao M,Zhao B,Chen M,Liu Y,Xu M,Wang Z,Liu S,Zhang C
Thu Jun 01 00:00:00 EDT 2017
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.
Biomaterials
Gao M,Zhao B,Chen M,Liu Y,Xu M,Wang Z,Liu S,Zhang C
Thu Jun 01 00:00:00 EDT 2017
Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers.
British journal of pharmacology
Magierowski M,Magierowska K,Hubalewska-Mazgaj M,Sliwowski Z,Ginter G,Pajdo R,Chmura A,Kwiecien S,Brzozowski T
Sun Oct 01 00:00:00 EDT 2017
Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers.
British journal of pharmacology
Magierowski M,Magierowska K,Hubalewska-Mazgaj M,Sliwowski Z,Ginter G,Pajdo R,Chmura A,Kwiecien S,Brzozowski T
Sun Oct 01 00:00:00 EDT 2017
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.
PLoS pathogens
Basu M,Courtney SC,Brinton MA
Wed Feb 01 00:00:00 EST 2017
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.
PLoS pathogens
Basu M,Courtney SC,Brinton MA
Wed Feb 01 00:00:00 EST 2017
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.
PLoS pathogens
Basu M,Courtney SC,Brinton MA
Wed Feb 01 00:00:00 EST 2017
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.
PLoS pathogens
Basu M,Courtney SC,Brinton MA
Wed Feb 01 00:00:00 EST 2017
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu YR,Ma H,Zou ZY,He K,Xiao YB,Wang Y,Feng M,Ye XL,Li XG
Sun Jan 01 00:00:00 EST 2017
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu YR,Ma H,Zou ZY,He K,Xiao YB,Wang Y,Feng M,Ye XL,Li XG
Sun Jan 01 00:00:00 EST 2017
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Oxidative medicine and cellular longevity
Wang Y,Gu YH,Liu M,Bai Y,Liang LY,Wang HL
Mon Mar 27 00:00:00 EDT 2017
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Oxidative medicine and cellular longevity
Wang Y,Gu YH,Liu M,Bai Y,Liang LY,Wang HL
Mon Mar 27 00:00:00 EDT 2017
Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1.
Oxidative medicine and cellular longevity
Liao HH,Zhu JX,Feng H,Ni J,Zhang N,Chen S,Liu HJ,Yang Z,Deng W,Tang QZ
Mon Jul 09 00:00:00 EDT 2018
Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1.
Oxidative medicine and cellular longevity
Liao HH,Zhu JX,Feng H,Ni J,Zhang N,Chen S,Liu HJ,Yang Z,Deng W,Tang QZ
Mon Jul 09 00:00:00 EDT 2018
Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1.
Oxidative medicine and cellular longevity
Liao HH,Zhu JX,Feng H,Ni J,Zhang N,Chen S,Liu HJ,Yang Z,Deng W,Tang QZ
Mon Jul 09 00:00:00 EDT 2018
Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1.
Oxidative medicine and cellular longevity
Liao HH,Zhu JX,Feng H,Ni J,Zhang N,Chen S,Liu HJ,Yang Z,Deng W,Tang QZ
Mon Jul 09 00:00:00 EDT 2018
Vitamin E antagonizes ozone-induced asthma exacerbation in Balb/c mice through the Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Duan L,Li J,Ma P,Yang X,Xu S
Fri Sep 01 00:00:00 EDT 2017
Vitamin E antagonizes ozone-induced asthma exacerbation in Balb/c mice through the Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Duan L,Li J,Ma P,Yang X,Xu S
Fri Sep 01 00:00:00 EDT 2017
Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen S,Li J,You H,Wu Z,Wu Y,Zhao Y,Zhu Y,Guo Q,Li X,Li R,Ma P,Yang X,Chen M
Sun Jan 01 00:00:00 EST 2017
Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen S,Li J,You H,Wu Z,Wu Y,Zhao Y,Zhu Y,Guo Q,Li X,Li R,Ma P,Yang X,Chen M
Sun Jan 01 00:00:00 EST 2017
Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li D,Dai C,Yang X,Wang F,Yu X,Xiao X,Tang S
Sun Oct 01 00:00:00 EDT 2017
Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li D,Dai C,Yang X,Wang F,Yu X,Xiao X,Tang S
Sun Oct 01 00:00:00 EDT 2017
Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6 via an Nrf2-mediated mitogen activated protein kinases pathway.
World journal of gastroenterology
Yang N,Shi JJ,Wu FP,Li M,Zhang X,Li YP,Zhai S,Jia XL,Dang SS
Tue Feb 21 00:00:00 EST 2017
Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6 via an Nrf2-mediated mitogen activated protein kinases pathway.
World journal of gastroenterology
Yang N,Shi JJ,Wu FP,Li M,Zhang X,Li YP,Zhai S,Jia XL,Dang SS
Tue Feb 21 00:00:00 EST 2017
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
World journal of gastroenterology
Sang L,Wang XM,Xu DY,Sang LX,Han Y,Jiang LY
Thu Dec 21 00:00:00 EST 2017
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
World journal of gastroenterology
Sang L,Wang XM,Xu DY,Sang LX,Han Y,Jiang LY
Thu Dec 21 00:00:00 EST 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
PPAR research
Wang Y,Zhao W,Li G,Chen J,Guan X,Chen X,Guan Z
Thu Oct 01 00:00:00 EDT 2020
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
PPAR research
Wang Y,Zhao W,Li G,Chen J,Guan X,Chen X,Guan Z
Thu Oct 01 00:00:00 EDT 2020
Nrf2-mediated neuroprotection by MANF against 6-OHDA-induced cell damage via PI3K/AKT/GSK3β pathway.
Experimental gerontology
Zhang J,Tong W,Sun H,Jiang M,Shen Y,Liu Y,Gu H,Guo J,Fang J,Jin L
Fri Dec 15 00:00:00 EST 2017
Nrf2-mediated neuroprotection by MANF against 6-OHDA-induced cell damage via PI3K/AKT/GSK3β pathway.
Experimental gerontology
Zhang J,Tong W,Sun H,Jiang M,Shen Y,Liu Y,Gu H,Guo J,Fang J,Jin L
Fri Dec 15 00:00:00 EST 2017
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Toxicology mechanisms and methods
Dai C,Lei L,Li B,Lin Y,Xiao X,Tang S
Wed Mar 01 00:00:00 EST 2017
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Toxicology mechanisms and methods
Dai C,Lei L,Li B,Lin Y,Xiao X,Tang S
Wed Mar 01 00:00:00 EST 2017
An inducible form of Nrf2 confers enhanced protection against acute oxidative stresses in RPE cells.
Experimental eye research
Vu KT,Hulleman JD
Wed Nov 01 00:00:00 EDT 2017
An inducible form of Nrf2 confers enhanced protection against acute oxidative stresses in RPE cells.
Experimental eye research
Vu KT,Hulleman JD
Wed Nov 01 00:00:00 EDT 2017
Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.
Molecular medicine reports
Wang Y,Gu YH,Liu M,Bai Y,Wang HL
Wed Feb 01 00:00:00 EST 2017
Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.
Molecular medicine reports
Wang Y,Gu YH,Liu M,Bai Y,Wang HL
Wed Feb 01 00:00:00 EST 2017
The therapeutic effect of zerumbone on chronic gastritis via antioxidant mechanisms.
Experimental and therapeutic medicine
Li L,Kong L,Song H
Fri Sep 01 00:00:00 EDT 2017
The therapeutic effect of zerumbone on chronic gastritis via antioxidant mechanisms.
Experimental and therapeutic medicine
Li L,Kong L,Song H
Fri Sep 01 00:00:00 EDT 2017
The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Magierowski M,Magierowska K,Surmiak M,Hubalewska-Mazgaj M,Kwiecien S,Wallace JL,Brzozowski T
Sun Oct 01 00:00:00 EDT 2017
The effect of hydrogen sulfide-releasing naproxen (ATB-346) versus naproxen on formation of stress-induced gastric lesions, the regulation of systemic inflammation, hypoxia and alterations in gastric microcirculation.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Magierowski M,Magierowska K,Surmiak M,Hubalewska-Mazgaj M,Kwiecien S,Wallace JL,Brzozowski T
Sun Oct 01 00:00:00 EDT 2017
NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway.
The Journal of biological chemistry
Bernard K,Logsdon NJ,Miguel V,Benavides GA,Zhang J,Carter AB,Darley-Usmar VM,Thannickal VJ
Fri Feb 17 00:00:00 EST 2017
NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway.
The Journal of biological chemistry
Bernard K,Logsdon NJ,Miguel V,Benavides GA,Zhang J,Carter AB,Darley-Usmar VM,Thannickal VJ
Fri Feb 17 00:00:00 EST 2017
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Redox biology
Liu S,Xin D,Wang L,Zhang T,Bai X,Li T,Xie Y,Xue H,Bo S,Liu D,Wang Z
Sun Oct 01 00:00:00 EDT 2017
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Redox biology
Liu S,Xin D,Wang L,Zhang T,Bai X,Li T,Xie Y,Xue H,Bo S,Liu D,Wang Z
Sun Oct 01 00:00:00 EDT 2017
Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia.
Theranostics
Feng L,Li J,Yang L,Zhu L,Huang X,Zhang S,Luo L,Jiang Z,Jiang T,Xu W,Wang X,Jin H
Tue Mar 06 00:00:00 EST 2018
Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia.
Theranostics
Feng L,Li J,Yang L,Zhu L,Huang X,Zhang S,Luo L,Jiang Z,Jiang T,Xu W,Wang X,Jin H
Tue Mar 06 00:00:00 EST 2018
Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia.
Theranostics
Feng L,Li J,Yang L,Zhu L,Huang X,Zhang S,Luo L,Jiang Z,Jiang T,Xu W,Wang X,Jin H
Tue Mar 06 00:00:00 EST 2018
Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia.
Theranostics
Feng L,Li J,Yang L,Zhu L,Huang X,Zhang S,Luo L,Jiang Z,Jiang T,Xu W,Wang X,Jin H
Tue Mar 06 00:00:00 EST 2018
Novel indolyl-chalcone derivatives inhibit A549 lung cancer cell growth through activating Nrf-2/HO-1 and inducing apoptosis in vitro and in vivo.
Scientific reports
Zhao X,Dong W,Gao Y,Shin DS,Ye Q,Su L,Jiang F,Zhao B,Miao J
Tue Jun 20 00:00:00 EDT 2017
Novel indolyl-chalcone derivatives inhibit A549 lung cancer cell growth through activating Nrf-2/HO-1 and inducing apoptosis in vitro and in vivo.
Scientific reports
Zhao X,Dong W,Gao Y,Shin DS,Ye Q,Su L,Jiang F,Zhao B,Miao J
Tue Jun 20 00:00:00 EDT 2017
Suppression of nuclear factor erythroid‑2‑related factor 2‑mediated antioxidative defense in the lung injury induced by chronic exposure to methamphetamine in rats.
Molecular medicine reports
Bai Y,Wang Y,Liu M,Gu YH,Jiang B,Wu X,Wang HL
Mon May 01 00:00:00 EDT 2017
Discovery of a novel Nrf2 inhibitor that induces apoptosis of human acute myeloid leukemia cells.
Oncotarget
Zhang J,Su L,Ye Q,Zhang S,Kung H,Jiang F,Jiang G,Miao J,Zhao B
Tue Jan 31 00:00:00 EST 2017
Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).
Scientific reports
Kemter E,Fröhlich T,Arnold GJ,Wolf E,Wanke R
Tue Feb 21 00:00:00 EST 2017
Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).
Scientific reports
Kemter E,Fröhlich T,Arnold GJ,Wolf E,Wanke R
Tue Feb 21 00:00:00 EST 2017
(-)-7(S)-hydroxymatairesinol protects against tumor necrosis factor-α-mediated inflammation response in endothelial cells by blocking the MAPK/NF-κB and activating Nrf2/HO-1.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang D,Xiao CX,Su ZH,Huang MW,Qin M,Wu WJ,Jia WW,Zhu YZ,Hu JF,Liu XH
Tue Aug 15 00:00:00 EDT 2017
SETD7 is a prognosis predicting factor of breast cancer and regulates redox homeostasis.
Oncotarget
Huang R,Li X,Yu Y,Ma L,Liu S,Zong X,Zheng Q
Tue Nov 07 00:00:00 EST 2017
SETD7 is a prognosis predicting factor of breast cancer and regulates redox homeostasis.
Oncotarget
Huang R,Li X,Yu Y,Ma L,Liu S,Zong X,Zheng Q
Tue Nov 07 00:00:00 EST 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways.
Redox biology
Zhang C,Li C,Chen S,Li Z,Jia X,Wang K,Bao J,Liang Y,Wang X,Chen M,Li P,Su H,Wan JB,Lee SMY,Liu K,He C
Sat Apr 01 00:00:00 EDT 2017
Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways.
Redox biology
Zhang C,Li C,Chen S,Li Z,Jia X,Wang K,Bao J,Liang Y,Wang X,Chen M,Li P,Su H,Wan JB,Lee SMY,Liu K,He C
Sat Apr 01 00:00:00 EDT 2017
Potential Ameliorative Effects of Qing Ye Dan Against Cadmium Induced Prostatic Deficits via Regulating Nrf-2/HO-1 and TGF-β1/Smad Pathways.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Du L,Lei Y,Chen J,Song H,Wu X
Mon Dec 18 00:00:00 EST 2017
Potential Ameliorative Effects of Qing Ye Dan Against Cadmium Induced Prostatic Deficits via Regulating Nrf-2/HO-1 and TGF-β1/Smad Pathways.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Du L,Lei Y,Chen J,Song H,Wu X
Mon Dec 18 00:00:00 EST 2017
Fibroblast growth factor-2-mediated protection of cardiomyocytes from the toxic effects of doxorubicin requires the mTOR/Nrf-2/HO-1 pathway.
Oncotarget
Koleini N,Nickel BE,Wang J,Roveimiab Z,Fandrich RR,Kirshenbaum LA,Cattini PA,Kardami E
Fri Oct 20 00:00:00 EDT 2017
3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice.
Free radical biology & medicine
Lu L,Dong J,Li D,Zhang J,Fan S
Sat Oct 01 00:00:00 EDT 2016
3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice.
Free radical biology & medicine
Lu L,Dong J,Li D,Zhang J,Fan S
Sat Oct 01 00:00:00 EDT 2016
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Clinical nutrition (Edinburgh, Scotland)
Shi H,Shi A,Dong L,Lu X,Wang Y,Zhao J,Dai F,Guo X
Thu Dec 01 00:00:00 EST 2016
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Clinical nutrition (Edinburgh, Scotland)
Shi H,Shi A,Dong L,Lu X,Wang Y,Zhao J,Dai F,Guo X
Thu Dec 01 00:00:00 EST 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
Protective Effects of Hydrogen Sulfide in the Ageing Kidney.
Oxidative medicine and cellular longevity
Hou CL,Wang MJ,Sun C,Huang Y,Jin S,Mu XP,Chen Y,Zhu YC
Mon Mar 13 00:00:00 EDT 2017
Protective Effects of Hydrogen Sulfide in the Ageing Kidney.
Oxidative medicine and cellular longevity
Hou CL,Wang MJ,Sun C,Huang Y,Jin S,Mu XP,Chen Y,Zhu YC
Mon Mar 13 00:00:00 EDT 2017
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
P21(Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng S,Tang S,Dai C,Zhou Y,Yang X,Li D,Xiao X
Mon Feb 01 00:00:00 EST 2016
P21(Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng S,Tang S,Dai C,Zhou Y,Yang X,Li D,Xiao X
Mon Feb 01 00:00:00 EST 2016
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Chemico-biological interactions
Han X,Li W,Huang D,Yang X
Sun Sep 25 00:00:00 EDT 2016
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Chemico-biological interactions
Han X,Li W,Huang D,Yang X
Sun Sep 25 00:00:00 EDT 2016
Taurine protects against As2O3-induced autophagy in pancreas of rat offsprings through Nrf2/Trx pathway.
Biochimie
Bai J,Yao X,Jiang L,Qiu T,Liu S,Qi B,Zheng Y,Kong Y,Yang G,Chen M,Liu X,Sun X
Fri Apr 01 00:00:00 EDT 2016
Taurine protects against As2O3-induced autophagy in pancreas of rat offsprings through Nrf2/Trx pathway.
Biochimie
Bai J,Yao X,Jiang L,Qiu T,Liu S,Qi B,Zheng Y,Kong Y,Yang G,Chen M,Liu X,Sun X
Fri Apr 01 00:00:00 EDT 2016
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Renal failure
Zhang W,Li Y,Ding H,Du Y,Wang L
Mon Aug 01 00:00:00 EDT 2016
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Renal failure
Zhang W,Li Y,Ding H,Du Y,Wang L
Mon Aug 01 00:00:00 EDT 2016
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Transplantation proceedings
Zhang P,Li Y,Du Y,Li G,Wang L,Zhou F
Thu Dec 01 00:00:00 EST 2016
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Transplantation proceedings
Zhang P,Li Y,Du Y,Li G,Wang L,Zhou F
Thu Dec 01 00:00:00 EST 2016
Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma.
The Journal of experimental medicine
Yang C,Tan YX,Yang GZ,Zhang J,Pan YF,Liu C,Fu J,Chen Y,Ding ZW,Dong LW,Wang HY
Mon May 02 00:00:00 EDT 2016
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Molecules (Basel, Switzerland)
Zhao L,Xu L,Tao X,Han X,Yin L,Qi Y,Peng J
Thu Jul 21 00:00:00 EDT 2016
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Molecules (Basel, Switzerland)
Zhao L,Xu L,Tao X,Han X,Yin L,Qi Y,Peng J
Thu Jul 21 00:00:00 EDT 2016
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Cell & bioscience
Liu J,Wu J,Sun A,Sun Y,Yu X,Liu N,Dong S,Yang F,Zhang L,Zhong X,Xu C,Lu F,Zhang W
Wed May 25 00:00:00 EDT 2016
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Cell & bioscience
Liu J,Wu J,Sun A,Sun Y,Yu X,Liu N,Dong S,Yang F,Zhang L,Zhong X,Xu C,Lu F,Zhang W
Wed May 25 00:00:00 EDT 2016
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Cell & bioscience
Liu J,Wu J,Sun A,Sun Y,Yu X,Liu N,Dong S,Yang F,Zhang L,Zhong X,Xu C,Lu F,Zhang W
Wed May 25 00:00:00 EDT 2016
Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats.
Frontiers in cellular neuroscience
Hu Q,Li T,Wang L,Xie Y,Liu S,Bai X,Zhang T,Bo S,Xin D,Xue H,Li G,Wang Z
Thu Oct 01 00:00:00 EDT 2020
Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats.
Frontiers in cellular neuroscience
Hu Q,Li T,Wang L,Xie Y,Liu S,Bai X,Zhang T,Bo S,Xin D,Xue H,Li G,Wang Z
Thu Oct 01 00:00:00 EDT 2020
Taurine protects against As2O3-induced autophagy in livers of rat offsprings through PPARγ pathway.
Scientific reports
Bai J,Yao X,Jiang L,Zhang Q,Guan H,Liu S,Wu W,Qiu T,Gao N,Yang L,Yang G,Sun X
Mon Jun 13 00:00:00 EDT 2016
Taurine protects against As2O3-induced autophagy in livers of rat offsprings through PPARγ pathway.
Scientific reports
Bai J,Yao X,Jiang L,Zhang Q,Guan H,Liu S,Wu W,Qiu T,Gao N,Yang L,Yang G,Sun X
Mon Jun 13 00:00:00 EDT 2016
Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways.
PloS one
Gao Z,Han Y,Hu Y,Wu X,Wang Y,Zhang X,Fu J,Zou X,Zhang J,Chen X,Jose PA,Lu X,Zeng C
Mon Jul 25 00:00:00 EDT 2016
Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways.
PloS one
Gao Z,Han Y,Hu Y,Wu X,Wang Y,Zhang X,Fu J,Zou X,Zhang J,Chen X,Jose PA,Lu X,Zeng C
Mon Jul 25 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice.
Toxicology research
Zhu Y,Li J,Wu Z,Lu Y,You H,Li R,Li B,Yang X,Duan L
Fri Jan 01 00:00:00 EST 2016
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Transcriptional upregulation centra of HO-1 by EGB via the MAPKs/Nrf2 pathway in mouse C2C12 myoblasts.
Toxicology in vitro : an international journal published in association with BIBRA
Wang J,Zhang L,Zhang Y,Luo M,Wu Q,Yu L,Chu H
Sun Mar 01 00:00:00 EST 2015
Transcriptional upregulation centra of HO-1 by EGB via the MAPKs/Nrf2 pathway in mouse C2C12 myoblasts.
Toxicology in vitro : an international journal published in association with BIBRA
Wang J,Zhang L,Zhang Y,Luo M,Wu Q,Yu L,Chu H
Sun Mar 01 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 EDT 2015
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 EDT 2015
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 EDT 2015
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 EDT 2015
