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FIGURE: 1 / 3
NSDHL Antibody (H00050814-D01P) in WB
Western Blot analysis of NSDHL expression in transfected 293T cell line (H00050814-T02) by NSDHL MaxPab polyclonal antibody.
Lane 1: NSDHL transfected lysate(41.90 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NSDHL transfected lysate(41.90 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00050814-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NSDHL (NP_057006.1, 1 a.a. approximately 373 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MEPAVSEPMR DQVARTHLTE DTPKVNADIE KVNQNQAKRC TVIGGSGFLG QHMVEQLLAR GYAVNVFDIQ QGFDNPQVRF FLGDLCSRQD LYPALKGVNT VFHCASPPPS SNNKELFYRV NYIGTKNVIE TCKEAGVQKL ILTSSASVIF EGVDIKNGTE DLPYAMKPID YYTETKILQE RAVLGANDPE KNFLTTAIRP HGIFGPRDPQ LVPILIEAAR NGKMKFVIGN GKNLVDFTFV ENVVHGHILA AEQLSRDSTL GGKAFHITND EPIPFWTFLS RILTGLNYEA PKYHIPYWVA YYLALLLSLL VMVISPVIQL QPTFTPMRVA LAGTFHYYSC ERAKKAMGYQ PLVTMDDAME RTVQSFRHLR RVK
Target Information
The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bare patches; NAD(P)-dependent steroid dehydrogenase-like protein; Protein H105e3; short chain dehydrogenase/reductase family 31E, member 1; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; striated
Gene Aliases: AI747449; Bpa; H105E3; NSDHL; SDR31E1; Str; XAP104
UniProt ID: (Human) Q15738, (Mouse) Q9R1J0
Entrez Gene ID: (Human) 50814, (Mouse) 18194
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
3-beta-hydroxy-delta5-steroid dehydrogenase activity
sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
dehydratase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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