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In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse Netrin-4 is observed, 15% cross-reactivity with recombinant chicken (rch) Netrin-1 is observed and less than 5% cross-reactivity with recombinant mouse (rm) Netrin-G1a, Netrin-G2a, and rchNetrin-2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
NTN4 contains 3 laminin EGF-like domains, 1 laminin N-terminal domain and 1 NTR domain. NTN4 may play an important role in neural, kidney and vascular development. It promotes neurite elongation from olfactory bulb explants. NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. (2000) [PubMed 11038171].[supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-netrin; CDY; CDY1A; FLJ23180; FLJ77185; Hepar-derived netrin-like protein; Netrin-4
Gene Aliases: NTN4; PRO3091
UniProt ID: (Human) Q9HB63
Entrez Gene ID: (Human) 59277
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