Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SDSEEEMKAL EADFLTNMHT SKISKAHVPS WKMTLLNVCS LVNNLNSPAE ETGEVHEEEL VARRKLPTAL DGFSLEAMLT IYQLHKICHS RAFQHWELIQ EDILDTGNDK NGKEEVIKRK IPYIL; Positive Samples: Mouse brain, Mouse kidney; Cellular Location: Cytoplasmic vesicle, secretory vesicle
NTS is a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
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Protein Aliases: neuromedin N; Neurotensin/neuromedin N; NmN
Gene Aliases: 5033428E16Rik; NMN-125; NN; NT; NT/N; Nts; NTS1
UniProt ID: (Mouse) Q9D3P9
Entrez Gene ID: (Mouse) 67405, (Rat) 299757
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