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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NEDD8 ultimate buster 1; NEDD8 ultimate buster-1; Negative regulator of ubiquitin-like proteins 1; NY-REN-18 antigen; Renal carcinoma antigen NY-REN-18
Gene Aliases: BS4; NUB1; NUB1L; NYREN18
UniProt ID: (Human) Q9Y5A7
Entrez Gene ID: (Dog) 475542, (Human) 51667, (Rat) 296731
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