Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: PQEVSLQDVR KEINFCRKVK LPIIGVVENM SGFICPKCKK ESQIFPPTTG GAELMCQDLE VPLLGRVPLD PLIGKNCDKG QSFFIDAPDS PATLAYRSII QRIQEFCNLH QSKEENLISS
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytosolic Fe-S cluster assembly factor NUBP1; cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000255|HAMAP-Rule:MF_03038}; NBP 1; NBP 1 {ECO:0000255|HAMAP-Rule:MF_03038}; NUBP1; nubp1 {ECO:0000312|EMBL:AAH88221.1}; nucleotide binding protein (e.coli MinD like); nucleotide binding protein 1 (E.coli MinD like); nucleotide binding protein 1 (MinD homolog, E. coli); Nucleotide-binding protein 1; nucleotide-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03038}
Gene Aliases: NBP; NBP1; NBP35; NUBP1
UniProt ID: (Human) P53384, (Mouse) Q9R060, (Rat) Q5I0L4
Entrez Gene ID: (Human) 4682, (Mouse) 26425, (Rat) 287042
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