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NUDT6 Antibody (PA5-102309) in IHC (P)
Immunohistochemistry analysis of NUDT6 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with NUDT6 polyclonal antibody (Product # PA5-102309) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102309
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NUDT6(Accession P53370), corresponding to amino acid residues V144-E194.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851718
Product Specific Information
Antibody detects endogenous levels of total NUDT6.
Target Information
NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6), also known as Antisense basic fibroblast growth factor or GFG-1, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. The gene encoding NUDT6 is a FGF-2 gene antisense transcript, and NUDT6 is believed to regulate FGF-2 expression. FGF-2 is a mutifunctional heparin-binding growth factor important to angiogenesis, neuroectoderm development and wound healing. NUDT6 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anti-sense basic fibroblast growth factor B; Antisense basic fibroblast growth factor; Antisense basic fibroblast growth factor B; Nucleoside diphosphate-linked moiety X motif 6; nudix (nucleoside diphosphate linked moiety X)-type motif 6; Nudix motif 6; Protein GFG
Gene Aliases: ASFGF2; Asfgf2b; FGF-AS; FGF2AS; Gfg; GFG-1; GFG1; NUDT6
UniProt ID: (Human) P53370, (Rat) P70563, (Mouse) Q8CH40
Entrez Gene ID: (Human) 11162, (Rat) 207120, (Mouse) 229228
growth factor activity
hydrolase activity
thiamine-pyrophosphatase activity
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
UDP-2,3-diacylglucosamine hydrolase activity
bis(5'-nucleosyl)-tetraphosphatase activity
dATP pyrophosphohydrolase activity
pyrophosphatase activity
dihydroneopterin monophosphate phosphatase activity
dihydroneopterin triphosphate pyrophosphohydrolase activity
dITP diphosphatase activity
dTTP diphosphatase activity
XTP diphosphatase activity
ATP-dependent 5'-3' DNA helicase activity
phosphocholine hydrolase activity
nucleotide phosphatase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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